Yini i-Olanzapine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Olanzapine iyimithi kadokotela esiza ukulinganisa amakhemikhali athile ebuchosheni bakho ukuze kuthuthukiswe izimpawu zempilo yengqondo. Ingaphansi kweqembu lemithi ebizwa ngokuthi ama-antipsychotics angajwayelekile, asebenza ngendlela ehlukile kunemithi endala yezengqondo futhi ngokuvamile abangeli imiphumela eminingi emibi.

Le mithi isize izigidi zabantu ukuthi baphathe izimo ezinjengesifo sengqondo kanye nesifo se-bipolar. Ukuqonda ukuthi isebenza kanjani nokuthi yini ongayilindela kungakusiza ukuthi uzizwe uqiniseka kakhulu ngohambo lwakho lokwelashwa.

Yini i-Olanzapine?

I-Olanzapine iyimithi yezempilo yengqondo esiza ukubuyisela ibhalansi kumakhemikhali obuchopho abizwa ngokuthi ama-neurotransmitters. Lawa makhemikhali athwala imiyalezo phakathi kwamaseli obuchopho, futhi lapho engalingani, kungabangela izimpawu ezinjengokucabanga, ukuguquguquka kwemizwa, noma ubunzima bokucabanga ngokucacile.

Cabanga nge-olanzapine njengomsizi omnene osebenza ngemuva kwezigcawu ukuze uzinzise amakhemikhali obuchopho bakho. Ithathwa njenge-atypical antipsychotic, okusho ukuthi uhlobo olusha lomuthi oluvame ukubangela imiphumela emibi engahlobene nokunyakaza kancane kunezidakamizwa ezindala zengqondo.

Umuthi uza ngesimo samaphilisi futhi uthathwa ngomlomo. Ihlolwe ngokucophelela futhi yavunywa yi-FDA yokwelapha izimo ezithile zempilo yengqondo ngokuphepha nangempumelelo.

Isetshenziselwani i-Olanzapine?

I-Olanzapine ikakhulukazi inikezwa ukwelapha isifo sengqondo kanye nesifo se-bipolar. Lezi yizimo ezingathi sína zempilo yengqondo ezingathinta kakhulu impilo yansuku zonke, kodwa ngokwelashwa okufanele, abantu abaningi baphila impilo egcwele, ekhiqizayo.

Ngokuqondene nesifo sengqondo, i-olanzapine isiza ukunciphisa izimpawu ezinjengokuzwa amazwi, ukubona izinto ezingekho, noma ukuba nemibono engavamile noma izinkolelo. Kungasiza futhi ngesikhuthazo nokusebenza komphakathi okuvame ukuba yinselele ngalesi simo.

Ngesifo se-bipolar, i-olanzapine isiza ukuzinzisa ukuguquguquka kwemizwa, ikakhulukazi iziqephu ze-manic lapho umuntu engase azizwe enomdlandla omkhulu, edinga ukulala okuncane, noma enze izinqumo ezingaqondakali. Ingasetshenziswa yodwa noma ihlanganiswe nezinye izinzisi zemizwa.

Ngezinye izikhathi odokotela banikeza i-olanzapine ezinye izimo uma bekholelwa ukuthi izosiza ngokusekelwe esimweni sakho esithile. Lokhu kubizwa ngokuthi ukusetshenziswa okungahleliwe futhi kuyingxenye ejwayelekile yomkhuba wezokwelapha.

Isebenza Kanjani I-Olanzapine?

I-Olanzapine isebenza ngokulungisa kancane umsebenzi wamakhemikhali amaningana obuchopho, ikakhulukazi i-dopamine ne-serotonin. Lawa ma-neurotransmitters adlala indima ebalulekile emizweni, ekucabangeni, nasekuqondeni.

Lapho lawa makhemikhali engalingani, kungabangela izimpawu ozihlangabezana nazo ngezimo zempilo yengqondo. I-Olanzapine isebenza njengendlela yokulungisa, isiza ukubuyisela ibhalansi ejwayelekile ngaphandle kokuvimba ngokuphelele lawa makhemikhali obalulekile obuchopho.

Lo muthi uthathwa njengomuthi oqinile futhi osebenzayo. Akuyona imithi yengqondo ethambile etholakalayo, kodwa futhi akuyona enamandla kakhulu. Abantu abaningi bathola ukuthi inikeza ukukhululeka okuhle kwezimpawu ngenkathi ibekezeleleka kahle.

Imiphumela ephelele ye-olanzapine ivame ukuthuthuka kancane kancane emasontweni amaningana. Ungase uqaphele ukuthuthuka kokulala noma ukucasuka ezinsukwini ezimbalwa zokuqala, kodwa izinzuzo eziphelele zezimpawu ezinjenge-hallucinations noma ukuguquguquka kwemizwa ngokuvamile kuthatha isikhathi eside ukuthi zivele.

Kufanele Ngiyithathe Kanjani I-Olanzapine?

Thatha i-olanzapine ngendlela eqondile udokotela wakho ayinikezayo, ngokuvamile kanye ngosuku ngesikhathi esifanayo nsuku zonke. Abantu abaningi bayithatha kusihlwa ngoba ingabangela ukozela, okungasiza ngempela ekulaleni.

Ungayithatha i-olanzapine ngaphandle noma ngaphandle kokudla. Uma ikucasula isisu sakho, ukuyithatha ngesnakhi esincane noma ukudla kungasiza. Gwema ukuyithatha notshwala, njengoba lokhu kungakhuphula ukozela neminye imiphumela emibi.

Gwinya ithebhulethi yonke ngengilazi yamanzi. Ungayichobozi, uyihlafune, noma uyiphule ithebhulethi ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze njalo. Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho mayelana nezinye izinketho.

Zama ukuthatha imithi yakho ngesikhathi esifanayo nsuku zonke ukuze ikusize ukhumbule futhi ugcine amazinga aqhubekayo ohlelweni lwakho. Ukusetha isikhumbuzi sefoni noma ukugcina imithi yakho eduze kwento oyisebenzisa nsuku zonke kungasiza ukusungula le nqubo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Olanzapine?

Ubude bokwelashwa nge-olanzapine buhlukahluka kakhulu kuye ngesimo sakho nokuthi usabela kanjani emuthini. Abantu abaningi badinga ukuyithatha izinyanga noma iminyaka ukuze bagcine ukuzinza kwempilo yabo yengqondo.

Ngesifo sengqondo, ukwelashwa kwesikhathi eside kuvamile ukuthi kudingeke ngoba kuyisimo esingamahlalakhona. Abantu abaningi baqhubeka nokuthatha i-olanzapine iminyaka, futhi abanye bangayidinga impilo yonke ukuze bavimbele ukubuyela kwezimpawu.

Ngesifo se-bipolar, ubude buxhomeke ezintweni eziningana ezihlanganisa ukuthi iziqephu zakho zinzima kangakanani nokuthi usabela kahle kangakanani ekwelashweni. Abanye abantu bayithatha kuphela ngesikhathi seziqephu ezinzima, kanti abanye badinga ukwelashwa okuqhubekayo ukuze bavimbele.

Ungayeki ukuthatha i-olanzapine ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa noma ukubuyela kwezimpawu zakho zokuqala. Udokotela wakho uzokwenza uhlelo lokunciphisa kancane uma udinga ukuyeka imithi.

Ziyini Imiphumela Eceleni ye-Olanzapine?

Njengayo yonke imithi, i-olanzapine ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi iyaphathwa futhi ivame ukuthuthuka njengoba umzimba wakho uzivumela emuthini emasontweni ambalwa okuqala.

Nawa imiphumela emibi evame kakhulu ongase uyithole:

• Ukozela noma ukuzwa ubuthongo emini
• Ukwanda kwesisindo, okungaba kubalulekile kwabanye abantu
• Ukukhuphuka kwesifiso sokudla
• Isiyezi, ikakhulukazi uma usukuma ngokushesha
• Umlomo owomile
• Ukuqunjelwa
• Ukungazinzi noma ukuzwa sengathi udinga ukuhambahamba

Le miphumela evamile emibi ivamise ukuba milde noma ibephakathi nendawo futhi ivame ukungabonakali njengoba umzimba wakho ujwayela umuthi.

Abanye abantu bangase babe nemiphumela emibi engathi sína edinga ukunakekelwa kwezempilo ngokushesha:

• Ukuqina kwemisipha okukhulu noma ama-spasms
• Umkhuhlane omkhulu onokujuluka nokudideka
• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Ubunzima bokugwinya noma ukuphefumula
• Isiyezi esikhulu noma ukuquleka
• Ukunyakaza okungajwayelekile ongakwazi ukukulawula
• Izimpawu zikashukela ophezulu njengokoma ngokweqile noma ukuchama

Ngenkathi le miphumela emibi engathi sína ingavamile, idinga ukunakekelwa kwezempilo ngokushesha uma kwenzeka. Udokotela wakho uzokuhlola njalo ukuze abambe noma yiziphi izinkinga ezingaba khona ekuqaleni.

Kukhona nokucatshangelwa kwesikhathi eside ngokusebenzisa i-olanzapine. Umuthi ungase uthinte imetabolism yakho, okungenzeka ukuthi kuholele ekuzuzeni isisindo, ukwanda kukashukela egazini, noma izinguquko emazingeni e-cholesterol. Udokotela wakho uzokuhlola lokhu ngezivivinyo zegazi ezivamile.

Ubani Ongafanele Athathwe I-Olanzapine?

I-Olanzapine ayifanele wonke umuntu, futhi izimo ezithile zezempilo noma izimo zingase zikwenze kungaphephile ukuthatha lo muthi. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuwubhala.

Akufanele uthathe i-olanzapine uma unokungezwani nayo noma uke waba nokusabela okukhulu emithini efanayo esikhathini esidlule. Izimpawu zokungezwani komzimba zihlanganisa ukuqubuka, ukuluma, ukuvuvukala, noma ubunzima bokuphefumula.

Abantu abanezimo ezithile zezempilo badinga ukucatshangelwa okukhethekile ngaphambi kokuthatha i-olanzapine:

• I-psychosis ehlobene ne-dementia (i-olanzapine ingakhuphula ingozi yokufa ezigulini ezindala ezinememori)
• Isifo sesibindi esibi kakhulu
• Izinkinga zesigqi senhliziyo noma ukuhlaselwa yinhliziyo kwakamuva
• Umlando wokuhlaselwa yisithuthwane
• Isifo sikashukela noma i-pre-diabetes
• Ukwehla kwesibalo samangqamuzana amhlophe egazi
• I-prostate enwetshiwe noma izinkinga zokuchama

Udokotela wakho uzoqaphela izinzuzo uma ziqhathaniswa nezingozi uma unesinye salezi zimo. Ngezinye izikhathi i-olanzapine isengasetshenziswa ngokuphepha ngokugadwa ngokucophelela.

Abantu abakhethekile nabo badinga ukucatshangelwa ngokucophelela. Abesifazane abakhulelwe kufanele bathathe i-olanzapine kuphela uma izinzuzo ziqeda izingozi enganeni esakhula. Uma uncelisa, umuthi ungangena obisini lwebele.

Iziguli ezindala, ikakhulukazi lezo ezinememori, zibhekene nezingozi ezengeziwe nge-olanzapine futhi zidinga ukuqashwa ngokucophelela kakhulu uma kunqunywe.

Amagama Omkhiqizo we-Olanzapine

I-Olanzapine itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Zyprexa iyona engaziwa kakhulu. Le yinguqulo eyathuthukiswa kuqala futhi yahlolwa kabanzi ezivivinyweni zomtholampilo.

Ungase futhi uhlangane nezinguqulo ze-generic ze-olanzapine, eziqulathe isithako esifanayo esisebenzayo kodwa zenziwe yizinkampani ezahlukene zemithi. Lezi zinguqulo ze-generic zisebenza kahle njengomuthi wegama lomkhiqizo kodwa zivame ukubiza kancane.

Ezinye izindlela zokwakheka zifaka i-Zyprexa Zydis, okuyithebhulethi encibilikayo encibilika olimini lwakho ngaphandle kwamanzi. Kukhona futhi uhlobo olujovwayo olubizwa nge-Zyprexa Relprevv kubantu abanobunzima bokuthatha imithi yomlomo yansuku zonke.

Noma ngabe uthatha inguqulo yegama lomkhiqizo noma i-generic akubalulekile ngokwezokwelapha. Ikhemisi lakho lingashintsha ngokuzenzakalelayo izinguqulo ze-generic ngaphandle kokuthi udokotela wakho abhale ngokuqondile ukuthi "umkhiqizo udingeka ngokwezokwelapha" emiyalweni yakho.

Ezinye izindlela ze-Olanzapine

Uma i-olanzapine ingasebenzi kahle kuwe noma idala imiphumela engathandeki, imithi eminingi ehlukile ingase ibe yizinketho. Udokotela wakho angakusiza ukuthi uhlole lezi ngokusekelwe ezimpawini zakho ezithile kanye nomlando wakho wezokwelapha.

Ezinye izidakamizwa ezingavamile ze-antipsychotics ezisebenza ngendlela efana ne-olanzapine zihlanganisa i-risperidone, i-quetiapine, i-aripiprazole, kanye ne-ziprasidone. Ngayinye inohlu oluncane oluhlukile lwemiphumela futhi ingasebenza kangcono kwabanye abantu.

Ngokuqondile ngokuqondene nesifo se-bipolar, izithuthukisi zemizwa ezinjenge-lithium, i-valproic acid, noma i-lamotrigine zingase zibe ezinye izindlela noma izithasiselo ohlelweni lwakho lokwelashwa. Le mithi isebenza ngendlela ehlukile kune-antipsychotics kodwa ingasebenza kahle kakhulu ezigabeni zemizwa.

Ukukhetha okunye kuncike ezintweni eziningi ezihlanganisa izimpawu zakho ezithile, ezinye izimo zempilo, ukusebenzisana okungenzeka kwemithi, kanye nezintandokazi zakho zomuntu siqu mayelana nemiphumela emibi. Ukuthola umuthi ofanele ngezinye izikhathi kuthatha ukubekezela nokusebenza eduze nodokotela wakho.

Ingabe i-Olanzapine Ingcono Kune-Risperidone?

Kokubili i-olanzapine ne-risperidone ziyizidakamizwa eziphumelelayo ezingavamile ze-antipsychotics, kodwa zinamandla ahlukene kanye nohlu lwemiphumela. Akukho noyedwa ongcono kunomunye - ukukhetha okungcono kuncike ezidingweni zakho zomuntu ngamunye nokuthi usabela kanjani emithini ngayinye.

I-Olanzapine ivame ukuba ne-sedating futhi maningi amathuba okuthi idale ukukhuluphala kanye nezinguquko ze-metabolic. Kodwa-ke, ingasebenza kangcono ezimpawini ezithile ezinjengokucasuka noma i-psychosis enkulu, futhi abanye abantu bathola ukuthi idala imiphumela emibi ehlobene nokunyakaza okuncane.

I-Risperidone ngokuvamile idala ukukhuluphala okuncane nezinkinga ze-metabolic kune-olanzapine, kodwa maningi amathuba okuthi idale imiphumela emibi yokunyakaza futhi ingase ikhulise amazinga e-prolactin, angathinta ama-hormone.

Udktela wakho uzocabangela izinto ezinjengezimpawu zakho ezithile, ezinye izimo zempilo, indlela yokuphila, nezintandokazi zomuntu siqu lapho ekhetha phakathi kwalawo makhambi. Ngezikhathi ezithile bangase bancomise ukuzama elilodwa kuqala, bese beshintsha uma kudingeka.

Imibuzo Evame Ukubuzwa Mayelana ne-Olanzapine

Q1. Ingabe i-Olanzapine iphephile kubantu abanesifo sikashukela?

I-Olanzapine ingathinta amazinga kashukela egazini futhi ingase yenze isifo sikashukela sibe sibi kakhulu noma ikhulise ingozi yokuthuthukisa isifo sikashukela. Kodwa-ke, ingasetshenziswa ngokuphepha kubantu abanesifo sikashukela ngokubheka ngokucophelela.

Udktela wakho uzofuna ukuhlola amazinga kashukela egazini lakho njalo uma unesifo sikashukela futhi uthatha i-olanzapine. Ungase udinge ukulungisa imithi yakho yesifo sikashukela noma uqaphele ushukela wakho wegazi kaningi.

Uma ungenaso isifo sikashukela kodwa unezici eziyingozi ezinjengomlando womndeni noma ukukhuluphala ngokweqile, udktela wakho uzokuqapha ukuze uthole izimpawu zokuthuthukisa isifo sikashukela ngenkathi uthatha i-olanzapine. Ukutholwa kwasekuqaleni nokuphathwa kungavimbela izinkinga ezinzima.

Q2. Kufanele ngenzeni uma ngiphuzile i-Olanzapine eningi ngengozi?

Uma ngengozi uphuza i-olanzapine eningi kunaleyo ebekiwe, xhumana nodktela wakho noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma uzizwa ulungile. Ukuphuza okuningi kungabangela imiphumela emibi engathi sína efana nokulala ngokweqile, ukudideka, noma izinkinga zesigqi senhliziyo.

Ungalindi ukubona ukuthi izimpawu ziyavela yini. Imiphumela yokweqisa ingase ingaveli ngokushesha, futhi ukuthola iseluleko sezokwelapha kusenesikhathi kuhlale kuphephe.

Uma othile ethatha umthamo omkhulu futhi engazi lutho noma enobunzima bokuphefumula, shayela ku-911 ngokushesha. Letha ibhodlela lemithi nawe egumbini eliphuthumayo ukuze abahlinzeki bezempilo bazi kahle ukuthi yini nokuthi kungakanani okuthathiwe.

Q3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Olanzapine?

Uma uphuthelwa umthamo we-olanzapine, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Kulokho, weqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esijwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ubuyisele umthamo owuphuthelwe. Lokhu kungakhuphula ingozi yakho yemiphumela emibi ngaphandle kokuhlinzeka ngenzuzo eyengeziwe.

Uma uvame ukukhohlwa imithamo, khuluma nodokotela wakho mayelana namaqhinga okukusiza ukuthi ukhumbule. Ukusetha ama-alamu ocingweni, ukusebenzisa umhleli wamaphilisi, noma ukuxhuma imithi yakho emsebenzini wansuku zonke kungakusiza ukuthi uhlale uqotho.

Q4. Ngingayeka nini ukuthatha i-Olanzapine?

Isinqumo sokuyeka i-olanzapine kufanele senziwe ngaso sonke isikhathi ngesiqondiso sikadokotela wakho. Abantu abaningi badinga ukuqhubeka beyithatha isikhathi eside ukuze bavimbele izimpawu ukuthi zingabuyi.

Udokotela wakho uzocabangela izinto ezinjengokuthi usunesikhathi esingakanani uzinzile, ubunzima besimo sakho, kanye nezimo zakho zomuntu siqu lapho nixoxa ngokuthi kufanelekile yini ukuyeka imithi.

Uma uyeka i-olanzapine, kuzokwenziwa kancane kancane ngokunciphisa kancane umthamo emasontweni noma ezinyangeni. Lokhu kusiza ukuvimbela izimpawu zokuhoxisa futhi kunciphisa ingozi yokuthi izimpawu zakho zokuqala zibuye ngokuzumayo.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Olanzapine?

Kungcono ukugwema utshwala ngenkathi uthatha i-olanzapine noma uphuze amanani amancane kakhulu ngemvume kadokotela wakho. Utshwala bungakhuphula imiphumela yokuthulisa ye-olanzapine, okukwenza ubuthongo obukhulu noma isiyezi.

Inhlanganisela ingase futhi ithinte ukwahlulela kwakho nokuxhumana kwakho ngaphezu kwento eyodwa, okwandisa ingozi yezingozi noma ukuwa.

Uma ukhetha ukuphuza ngezikhathi ezithile, qala ngamanani amancane kakhulu ukuze ubone ukuthi umzimba wakho usabela kanjani, futhi ungalokothi uphuze bese ushayela. Yiba qotho nodokotela wakho mayelana nokusetshenziswa kwakho kotshwala ukuze bakunikeze isiqondiso esiphephe kakhulu sesimo sakho.