Paclitaxel (indlela ye-intravenous)
Imikhiqizo etholakalayo
Nov-Onxol, Onxol, Paclitaxel Novaplus, Taxol
Mayelana naleli khambi
Ukuhlungwa kwePaclitaxel kusetshenziswa ekwelapheni umdlavuza ophambili wezibeletho, amabele, umdlavuza wephunga ongenayo i-cell encane, neKaposi sarcoma. I-Kaposi sarcoma yilomdlavuza wesikhumba nezinye izingqimba ezinobuthi ekutholwa njalo kubantu abane-acquired immunodeficiency syndrome (AIDS). I-Paclitaxel iyingxenye yemithi ebizwa ngokuthi yi-antineoplastics. Iphazamisa ukukhula kwamaseli omdlavuza, awohloka ekugcineni. Njengoba ukukhula kwamaseli omzimba ajwayelekile kungase kuthonyeke, eminye imiphumela engathandeki nayo izovele. Eminye yale miphumela ingaba nzima futhi kufanele uyibeke umbiko kudokotela wakho. Eminye imiphumela ingase ingabi nzima kodwa ingase ikhathaze. Eminye imiphumela ingase ingabonakali kuze kube ngeminyaka noma izinyanga ngemuva kokusetshenziswa kwale mithi. Ngaphambi kokuba uqale ukwelashwa nge-paclitaxel, wena nodokotela wakho kufanele nixoxe ngezinzuzo zalemithi kanye nezingozi zokuyisebenzisa. Lemithi kufanele inikezwe kuphela ngaphansi kokunakekelwa okusheshayo kudokotela wakho. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Umakuqondisa ekusebenziseni imithi, kufanele kuqhathaniswe ingozi yokusebenzisa imithi nezinzuzo ezizolethwa yiyo. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqondile noma oluhambelanayo lokuphazamiseka kule mithi noma kwezinye izidakamizwa. Tshela odokotela wakho uma unanoma yiluphi olunye uhlobo lokuphazamiseka, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenaso iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Akwenziwanga ucwaningo olufanele mayelana nobudlelwano phakathi kweminyaka nemiphumela yokubeka i-paclitaxel kubantwana. Ukuphepha nokuphumelela akukaqiniswa. Ucwaningo olufanele oluqediwe kuze kube manje alubonisi izinkinga ezikhethekile zabantu abadala ezingalawula ukusetshenziswa kwe-paclitaxel injection kubantu abadala. Kodwa-ke, abantu abadala banamathuba amaningi okuba nemiphumela emibi (isib. isifo senhliziyo, izinkinga ze-bone marrow, nezinkinga zezinzwa), okungadinga ukuqapha kubantu abamukela i-paclitaxel injection. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma wamukele le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma yimiphi imithi ehlaliswe ngezansi. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo ayikhuthazwa. Udokotela wakho angase anqume ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo ngokuvamile ayikhuthazwa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili izidakamizwa. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo kungabangela ukwanda kengozi yemiphumela emibi ethile, kodwa ukusebenzisa kokubili izidakamizwa kungaba ukwelashwa okuhle kuwe. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili izidakamizwa. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla ngoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba nanoma yimiphi imithi kungabangela ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi esetshenziswa ekwelapheni umdlavuza inamandla kakhulu futhi ingaba nemiphumela eminingi engathandeki. Ngaphambi kokuthola le mithi, wena nodokotela wakho kufanele nixoxe ngezinzuzo zalemi thi kanye nezingozi zokuyisebenzisa. . Udokotela noma omunye ochwepheshe bezempilo oqeqeshwe uzohlinzeka ngale mithi esibhedlela noma esikhungweni sokwelapha umdlavuza. Lemithi inikezwa ngenhlanzi ebekwe kwenye yezinzwa zakho. Lemithi ivame ukunikezwa njalo ngemva kwamasonto amathathu futhi isebenzisana neminye imithi yomdlavuza, efana ne cisplatin noma i doxorubicin. Ungase futhi uthole eminye imithi ezosiza ukuvimbela ukusabela okungafani nemizwa noma ukugabha okuvela ku paclitaxel.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.