Palbociclib (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Ibrance
Mayelana naleli khambi
IPalbociclib isetshenziswa ekwelapheni lomdlavuza wamabele oqhubekayo noma ophazamisekile (umdlavuza osuke usakazeke) ophethwe yi-hormone receptor (HR)-positive, HER-2 negative. Lena imithi isetshenziswa ndawonye ne-aromatase inhibitor (isib. i-letrozole) njengonyango lokuqala olusekelwe kwi-hormone noma ne-fulvestrant kubantu abanesifo esiphuphumayo ngemuva kokwelashwa kwe-hormone. Iyingxenye yeqembu lemithi ebizwa ngokuthi yi-antineoplastics. I-Palbociclib iphazamisa ukukhula kwamaseli omdlavuza, aqothulwa ekugcineni. Njengoba ukukhula kwamaseli avamile kungase kuthonyeke nalo muthi, kuzovela nezinye izingozi. Ezinye zazo zingaba nzima futhi kufanele zibikwe kudokotela wakho. Lo muthi utholakala kuphela ngomyalo wodokotela. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoyiletha. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqondile noma oluhambelanayo lwe-allergic kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo ze-allergies, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela ye-palbociclib kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingakhawulela ukusetshenziswa kwe-palbociclib kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungadingeka. Uma uthatha le mithi, kubaluleke kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile akuyona into enconywayo, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyisebenzisa kangakanani enye noma zombili imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla ngoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungase futhi kubangele ukusebenzisana. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile akuyona into enconywayo, kodwa kungase kungakugwemeki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi ebizwa ngokuthi i-cancer inamandla kakhulu futhi ingaba nemiphumela eminingi emibi. Ngaphambi kokusebenzisa le mithi, qiniseka ukuthi uyayiqonda yonke imingcipheko nezinzuzo. Kubalulekile ukuthi usebenzisane eduze nodokotela wakho ngesikhathi sokwelashwa kwakho. Thatha le mithi ngokuqondile njengoba uqondiswe yidokotela wakho. Ungayithathi ngaphezulu, ungayithathi kaningi, futhi ungayithathi isikhathi eside kunalokho oqondiswe yidokotela wakho. Le mithi iza ne-insert yolwazi lwabaguli. Funda bese ulandela imiyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. I-Palbociclib inikezwa kanye ne-letrozole noma i-fulvestrant. Kubalulekile ukuthi uthathe imithi ngayinye ngesikhathi esifanele. Landela imiyalo yodokotela wakho mayelana nokuthi nini kufanele uthathe le mithi. Udokotela wakho angakunika neminye imithi (eg, i-luteinizing hormone-releasing hormone agonists) ngokuhlanganyela ne-palbociclib kanye ne-letrozole noma i-fulvestrant uma ungowesifazane ongaphambi/ngesikhathi sokuqala kwesikhathi sakho noma indoda. Gwinya ikhaphsuli noma ithebulethi yonke. Ungayivuli, ungayicwili, ungayaphula, noma ungayikhinye. Thatha amakhaphsuli omhlathi ngokudla. Thatha amathebulethi omhlathi ngokudla noma ngaphandle kokudla. Ungadli i-grapefruit noma uphuze ijusi le-grapefruit ngesikhathi usebenzisa le mithi. Inani lemithi le mithi lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi ale mithi. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lemithi oyithatha lixhomeke emandleni emithi. Futhi, inani lezinye uzithatha nsuku zonke, isikhathi esivunyelwe phakathi kwezinye, nobude besikhathi othatha imithi kuya ngenkinga yezokwelapha oyisebenzisela imithi. Uma uphuthelwa yisilinganiso sale mithi, susa isilinganiso esiphuthelwe bese ubuyela esikhathini sakho sokuthatha imithi. Ungawandisi ama-doses. Uma uphuthelwa yisilinganiso noma uhlanza ngemuva kokuthatha le mithi, ungayithathi enye isilinganiso ngosuku olufanayo. Linda kuze kube yisilinganiso sakho esilandelayo bese uyithatha uma ubungayithatha ngokujwayelekile. Gcina imithi esitsheni esivalekile ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungayivumeli ukuba iqhube. Gcina ingafinyeleleki kubantwana. Ungagcini imithi esele iphelile noma imithi engasasetshenziswa. Buza ochwepheshe bezempilo ukuthi kufanele uyilahla kanjani imithi oyisebenzisayo.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.