Yini i-Paliperidone: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Paliperidone iyimithi elwa nokucindezeleka engasiza ekuphatheni izimpawu ze-schizophrenia kanye ne-schizoaffective disorder. Isebenza ngokulinganisela amakhemikhali athile ebuchosheni abizwa ngokuthi ama-neurotransmitters, ikakhulukazi i-dopamine ne-serotonin, angase angalingani kulezi zimo. Le mithi iyindlela esebenzayo ye-risperidone, okusho ukuthi umzimba wakho uguqula i-risperidone ibe yi-paliperidone ngokwemvelo.

Uma wena noma othile omkhathalelayo enikwe i-paliperidone, cishe ufuna ulwazi olucacile, oluqotho mayelana nokuthi yini ongayilindela. Ake sihambe kukho konke okudingeka ukwazi ngale mithi ngendlela ezizwa ilawuleka futhi iqinisekisa.

Yini i-Paliperidone?

I-Paliperidone ingeyeqembu lemithi ebizwa ngokuthi ama-antipsychotics angajwayelekile noma ama-antipsychotics esizukulwane sesibili. Le mithi isiza ukubuyisela ukulinganisela kwezinto zemvelo ebuchosheni bakho ezithinta imizwa, ukucabanga, nokuziphatha. Cabanga ngayo njengokusiza uhlelo lokuxhumana lobuchopho bakho ukuthi lusebenze kahle.

Le mithi iza ngamaphilisi akhishwe isikhathi eside, okusho ukuthi imithi ikhishwa kancane emzimbeni wakho usuku lonke. Lo mklamo usiza ukugcina amazinga aqinile emithi emzimbeni wakho, okungaholela ekulawuleni okungcono izimpawu ezinokwehla nokukhuphuka okuncane.

I-Paliperidone ithathwa njengemithi elwa nokucindezeleka enamandla amaphakathi. Isebenza ngempumelelo ekuphatheni izimpawu ngenkathi ngokuvamile inemiphumela emihle eceleni uma iqhathaniswa nemithi endala elwa nokucindezeleka.

Yini i-Paliperidone Esetshenziselwa Yona?

I-Paliperidone ikakhulukazi inikezwa ukwelapha i-schizophrenia kanye ne-schizoaffective disorder kubantu abadala nasebancane. Lezi zimo zingabangela izimpawu ezinjengokucabanga ngamanga, ukukhohlisa, ukucabanga okungahlelekile, kanye nezinguquko zemizwa ezinomthelela omkhulu empilweni yansuku zonke.

Ngesifo sengqondo, i-paliperidone isiza ukunciphisa lokho odokotela abakubiza ngokuthi "izimpawu ezinhle" njengokuzwa izwi noma ukubona izinto ezingekho, kanye "nezimpawu ezingezinhle" njengokuzihoxisa emisebenzini yomphakathi noma ukunciphisa ukubonakaliswa kwemizwa. Kungasiza futhi ngezimpawu zokuqonda ezithinta inkumbulo nokucabanga.

Ngesifo se-schizoaffective, umuthi ubhekana nezimpawu ze-psychotic kanye nezimpawu zemizwa njengokucindezeleka noma i-mania. Abanye odokotela bangase futhi banikeze i-paliperidone ngaphandle kwelebula kwezinye izimo, kodwa lokhu kufanele kuxoxwe ngokucophelela nodokotela wakho.

Isebenza Kanjani I-Paliperidone?

I-Paliperidone isebenza ngokuvimba ama-receptors athile ebuchosheni bakho, ikakhulukazi ama-dopamine kanye nama-serotonin receptors. Lapho lawa makhemikhali obuchopho engalingani, angabangela izimpawu ezihambisana nesifo sengqondo kanye nesifo se-schizoaffective.

Ngokuvimba lawa ma-receptors, i-paliperidone isiza ukubuyisela ukulinganisela okujwayelekile kwamakhemikhali obuchopho. Lokhu akwenzeki ngobusuku obubodwa - ngokuvamile kuthatha amasonto amaningana ukubona izinzuzo eziphelele zomuthi. Abanye abantu bangase babone ngcono ekulaleni nasekuthukutheleni ezinsukwini zokuqala, kanti ezinye izimpawu zingase zithathe isikhathi eside ukuthuthuka.

Ifomula yomuthi yokukhishwa isikhathi eside isho ukuthi isebenza ngokuqhubekayo usuku lonke. Lesi senzo esiqhubekayo sisiza ukugcina ukulawulwa kwezimpawu okuqhubekayo futhi singanciphisa amathuba ezimpawu zokuphuma.

Kufanele Ngiyithathe Kanjani I-Paliperidone?

Thatha i-paliperidone ngendlela enembile njengoba udokotela wakho ekunqumele ngayo, ngokuvamile kanye ngosuku ekuseni. Amaphilisi kufanele agwinywe wonke ngamanzi - ungaqedi, uhlafune, noma uwaphule, ngoba lokhu kungaphazamisa indlela yokukhishwa isikhathi eside.

Ungathatha i-paliperidone ngaphandle noma ngaphandle kokudla, kodwa zama ukungaguquguquki ngokukhetha kwakho. Uma uthola ukuthi kubangela ukuphazamiseka kwesisu, ukuyithatha ngokudla kungase kusize. Abanye abantu bathola ukuthi ukuyithatha nge-breakfast kubasiza ukuthi bakhumbule umthamo wabo wansuku zonke.

Kubalulekile ukuthatha i-paliperidone ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo emzimbeni wakho. Ukusetha i-alamu yansuku zonke noma ukusebenzisa umhleli wamaphilisi kungakusiza ukuthi usungule le nqubo. Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho mayelana nezinye izindlela esikhundleni sokuzama ukuqhekeza umuthi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Paliperidone?

Ubude bokwelashwa nge-paliperidone buhluka kakhulu kumuntu nomuntu futhi kuncike esimweni sakho esithile nokuphendula emuthini. Abantu abaningi abane-schizophrenia noma i-schizoaffective disorder badinga ukwelashwa kwesikhathi eside ukuze bagcine ukulawulwa kwezimpawu futhi bavimbele ukuphindeka.

Udkt wakho ngokuvamile uzoqala ngomthamo ophansi osebenzayo futhi angawulungisa emasontweni amaningana noma izinyanga ezimbalwa. Uma usutholile umthamo okusebenzelayo kuwe, abantu abaningi baqhubeka nokuthatha i-paliperidone iminyaka eminingi ukuze bagcine ukuzinza. Lokhu akunjalo ngoba umuthi uyalutha, kodwa ngoba lezi zimo zivame ukudinga ukuphathwa okuqhubekayo.

Ungayeki ukuthatha i-paliperidone ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe kungaholela ezimpawini zokuhoxisa kanye nokubuyela kwezimpawu zakho zokuqala. Uma wena nodokotela wakho ninquma ukuyeka umuthi, bazokwenza uhlelo lokunciphisa kancane umthamo wakho ngokuhamba kwesikhathi.

Yiziphi Imiphumela Eceleni Ye-Paliperidone?

Njengayo yonke imithi, i-paliperidone ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi uzizwe ulungile futhi wazi ukuthi ungaxhumana nini nomhlinzeki wakho wezempilo.

Imiphumela emibi evame kakhulu abantu abayitholayo ngokuvamile iyaphathwa futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi:

• Ukozela noma ukuzwa ukhathele emini
• Isiyezi, ikakhulukazi uma usukuma ngokushesha
• Ukukhathwa yikhanda
• Isicanucanu noma ukungakhululeki kwesisu
• Ukuqunjelwa
• Umlomo owomile
• Ukukhuluphala
• Ukungazinzi noma ukuzizwa ungenakuzinza

Le miphumela evamile ngokuvamile imnene kuya kokulingene futhi ivame ukwehla ngokuhamba kwesikhathi. Ukuhlala unamanzi, ukudla ukudla okuvamile, nokusukuma kancane ezindaweni zokuhlala noma zokuqamba amanga kungasiza ekunciphiseni eminye yale miphumela.

Abanye abantu bangase babe nemiphumela emibi kakhulu edinga ukunakekelwa kwezempilo ngokushesha. Ngenkathi lokhu kungavamile, kubalulekile ukukwazi:

• Ukuqina kwemisipha okukhulu noma ama-spasms
• Umkhuhlane omkhulu nokujuluka nokudideka
• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Ubunzima bokugwinya noma ukuphefumula
• Ukunyakaza okungalawuleki kobuso, ulimi, noma izitho
• Isiyezi esikhulu noma ukuquleka
• Izimpawu zikashukela ophezulu njengokoma ngokweqile noma ukuchama

Le miphumela emibi kakhulu ayivamile, kodwa uma uhlangabezana nanoma iyiphi yayo, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezempilo eziphuthumayo. Ithimba lakho lezempilo lilapho ukukusiza ukuthi ulawule noma yimiphumela emibi eyenzekayo.

Ubani Ongafanele Athathwe I-Paliperidone?

I-Paliperidone ayifanele wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyibhala. Ezinye izimo nezimo zingenza lo muthi ungafaneleki noma zidinge ukuqapha okukhethekile.

Akufanele uthathe i-paliperidone uma unokungezwani komzimba ne-paliperidone, i-risperidone, noma yiziphi izithako ezingasebenzi emaphilisi. Abantu abanezimo ezithile zenhliziyo, ikakhulukazi labo abanomlando wokushaya kwenhliziyo okungajwayelekile, bangase badinge ukwelashwa okuhlukile noma ukuqapha okucophelelayo kakhulu.

Udokotela wakho uzodinga ukwazi ngalezi zimo ezibalulekile zezempilo ngaphambi kokubhala i-paliperidone:

• Izinkinga zenhliziyo noma umlando womndeni wokuphazamiseka kwesigqi senhliziyo
• Isifo sikashukela noma umlando womndeni wesifo sikashukela
• Isifo sesibindi noma sezinso
• Umlando wokushaywa yisithuthwane noma isifo sokuwa
• Isifo sikaParkinson noma i-dementia
• Umlando wokushaywa unhlangothi noma ama-mini-strokes
• Ubunzima bokugwinya
• Ukwehla kwenani lamangqamuzana amhlophe egazi

Ukukhulelwa nokuncelisa ngamabele kudinga ukucatshangelwa okukhethekile. Ngenkathi i-paliperidone ingase idingeke kwabanye besifazane abakhulelwe, ingase ithinte ingane esakhula. Udokotela wakho uzohlola ngokucophelela izinzuzo nezingozi uma ukhulelwe noma uhlela ukukhulelwa.

Amagama Omkhiqizo we-Paliperidone

I-Paliperidone itholakala ngaphansi kwegama lomkhiqizo elithi Invega ngamaphilisi omlomo akhishwe isikhathi eside. Umuthi futhi uyatholakala njengenguqulo ejwayelekile, equkethe isithako esifanayo esisebenzayo futhi esebenza ngendlela efanayo nenguqulo yegama lomkhiqizo.

Kukhona futhi uhlobo olujovwayo olubizwa nge-Invega Sustenna, olunikezwa njengesijovo sanyanga zonke, kanye ne-Invega Trinza, enikezwa njalo ezinyangeni ezintathu. Lezi zinhlobo ezinjovwayo zingase zibe izinketho uma unobunzima bokukhumbula ukuthatha imithi yansuku zonke noma ukhetha ukulinganisa okungavamile.

Noma ngabe uthola igama lomkhiqizo noma inguqulo ejwayelekile, umuthi kufanele usebenze kahle ngokulinganayo. Ikhemisi lakho lingase lishintshe ngokuzenzakalelayo inguqulo ejwayelekile ngaphandle kokuthi udokotela wakho acele ngokuqondile igama lomkhiqizo.

Ezinye izindlela ze-Paliperidone

Uma i-paliperidone ingakulungele, kunemithi eminingi eyi-antipsychotic enye udokotela wakho angayicabangela. Umuntu ngamunye usabela ngendlela ehlukile emithini, ngakho-ke ukuthola okulungile ngezinye izikhathi kuthatha ukubekezela nokubambisana nethimba lakho lezempilo.

Ezinye izidakamizwa ezingavamile ze-antipsychotics ezisebenza ngendlela efanayo ne-paliperidone zihlanganisa i-risperidone (i-paliperidone ethathwe kuyo), i-aripiprazole, i-olanzapine, ne-quetiapine. Ngayinye yale mithi inezinzuzo zayo kanye nemiphumela engemihle engaba khona.

Udktora wakho angase futhi acabangele imithi endala ye-antipsychotic efana ne-haloperidol noma i-chlorpromazine, nakuba lezi zivame ukuba nemiphumela eminingi ehlobene nokunyakaza. Ukukhetha okunye kuncike ezimpawini zakho ezithile, umlando wezokwelapha, nokuthi usabele kanjani kwezinye izindlela zokwelapha.

Ingabe i-Paliperidone Ingcono Kune-Risperidone?

I-Paliperidone ne-risperidone ziyimithi ehlobene eduze - i-paliperidone empeleni iyi-metabolite esebenzayo ye-risperidone. Lokhu kusho ukuthi uma uthatha i-risperidone, umzimba wakho uyiguqula ibe yi-paliperidone ukuze ikhiqize imiphumela yayo yokwelapha.

Inzuzo enkulu ye-paliperidone ngaphezu kwe-risperidone ukuthi idlula inqubo yokuguqulwa kwesibindi, engahluka kumuntu nomuntu. Lokhu kusho ukuthi i-paliperidone ingahlinzeka ngamazinga egazi aqhubekayo futhi mhlawumbe ukuxhumana okumbalwa kwemithi njengoba inganciki kuma-enzyme esibindi ukuze isebenze.

Abanye abantu ababa nemiphumela emibi nge-risperidone bangase bayibekezelele kangcono i-paliperidone, kanti abanye bangase bakhethe i-risperidone. Ifomula yokukhishwa okwandisiwe ye-paliperidone futhi inikeza lula lokuthatha umthamo kanye ngosuku, kuyilapho i-risperidone ivame ukuthathwa kabili ngosuku. Udokotela wakho angasiza ekunqumeni ukuthi iyiphi imithi efaneleka kakhulu esimweni sakho esithile.

Imibuzo Evame Ukubuzwa Mayelana ne-Paliperidone

Ingabe i-Paliperidone Iphephile Kubantu Abanesifo Sikashukela?

I-Paliperidone ingasetshenziswa kubantu abanesifo sikashukela, kodwa idinga ukuqapha ngokucophelela. Umuthi ungase ukwazi ukunyusa amazinga kashukela egazini futhi ungase uqhubeke nokulawula isifo sikashukela kwabanye abantu. Udokotela wakho cishe uzofuna ukuhlola ushukela wakho wegazi kaningi lapho uqala i-paliperidone.

Uma unesifo sikashukela, qiniseka ukuthi uqhubeka nokuqapha ushukela wakho wegazi njengoba kunconywe yithimba lakho lezempilo. Abanye abantu bangase badinge ukulungiswa emithini yabo yesifo sikashukela lapho beqala i-paliperidone. Izinzuzo zokwelapha isimo sakho sengqondo zivame ukudlula lezi zingozi uma ziphathwa kahle.

Kumele Ngenzeni Uma Ngithathe I-Paliperidone Eningi Ngengozi?

Uma ngengozi uthatha i-paliperidone eningi kunaleyo oyinikiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, noma uye egumbini eliphuthumayo eliseduze. Ukuthatha i-paliperidone eningi kungabangela izimpawu ezinzima njengobuthongo obukhulu, ukushaya kwenhliziyo okusheshayo, ukuqina kwemisipha, noma ubunzima bokuphefumula.

Ungalindi ukubona ukuthi uzizwa ulungile yini - kungcono ukufuna usizo lwezokwelapha ngokushesha. Letha ibhodlela lomuthi nawe ukuze abahlinzeki bezempilo bazi kahle ukuthi yini nokuthi ungakanani okuthathile. Isikhathi sibalulekile ekweqiseni imithi, ngakho-ke unganqikazi ukuthola usizo.

Kumele Ngenzeni Uma Ngedlula Umthamo We-Paliperidone?

Uma udlula umthamo we-paliperidone, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo odlulisiwe bese uqhubeka neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo odlulisiwe.

Ukuphuthelwa imithamo ngezikhathi ezithile ngokuvamile akuyingozi, kodwa zama ukugcina ukuqina ukuze uthole ukulawulwa okungcono kakhulu kwezimpawu. Uma uvame ukukhohlwa imithamo, khuluma nodokotela wakho ngamasu okukusiza ukuthi ukhumbule, njengokusetha ama-alamu ocingo noma ukusebenzisa umhleli wamaphilisi.

Ngingayeka Nini Ukuthatha I-Paliperidone?

Isinqumo sokuyeka ukuthatha i-paliperidone kufanele senziwe ngaso sonke isikhathi ngokubambisana nodokotela wakho. Abantu abaningi abanesifo sengqondo noma isifo esihlobene nesifo sengqondo badinga ukwelashwa kwesikhathi eside ukuze bagcine ukuzinza futhi bavimbele ukuvela kabusha kwezimpawu.

Uma wena nodokotela wakho ninquma ukuthi kufanelekile ukuyeka i-paliperidone, bazokwakha uhlelo lokunciphisa kancane kancane ukunciphisa umthamo wakho kancane kancane ngokuhamba kwesikhathi. Lokhu kusiza ekuvikeleni izimpawu zokuhoxiswa futhi kunciphisa ingozi yokuphindeka kwezimpawu. Ungalokothi uyeke ukuthatha i-paliperidone ngokuzumayo wedwa.

Ngingakwazi Yini Ukuphuza Utshwala Ngenkathi Ngithatha I-Paliperidone?

Kungcono ukugwema utshwala ngenkathi uthatha i-paliperidone noma ukunciphise kakhulu. Utshwala bungakhuphula ukozela nesiyezi esibangelwa yi-paliperidone, okwenza kube yingozi ukuqhuba imoto noma ukusebenzisa imishini. Utshwala bungase futhi buqhubeke nezimpawu ze-schizophrenia kanye ne-schizoaffective disorder.

Uma ukhetha ukuphuza utshwala ngezikhathi ezithile, xoxa ngalokhu nodokotela wakho kuqala. Bangakunikeza isiqondiso semikhawulo ephephile futhi bakusize uqonde izingozi. Khumbula ukuthi utshwala bungaphazamisa nokulala kwakho nempilo yakho yonke yengqondo, okungase kuphikise izinzuzo zomuthi wakho.