Panitumumab (indlela ye-intravenous)
Imikhiqizo etholakalayo
Vectibix
Mayelana naleli khambi
Isikhubekiso sePanitumumab sisetshenziswa sodwa noma ngokubambisana nezinye izidakamizwa zokwelapha umdlavuza osakazekile (umdlavuza osakazekile ezingxenyeni zomzimba) wesisu noma umgudu kubantu abake bamukele ezinye izindlela zokwelapha umdlavuza. Isikhubekiso sePanitumumab kufanele sisetshenziswe kuphela kulabo abane-wild type RAS (ku-KRAS nase-NRAS) ukuhlolwa kwe-gene mutation. Lolu viwo lusiza udokotela ukuthi anqume ukuthi le mithi izowelapha yini umdlavuza wabo. I-Panitumumab iphazamisa ukukhula kwamaseli omdlavuza, awohloka ekugcineni ngumzimba. Njengoba ukukhula kwamaseli omzimba ajwayelekile kungase kuthonyeke yi-panitumumab, kuzoba nezinye iziphumo. Ezinye zalezi zingaba nzima futhi kufanele zibikwe kudokotela wakho. Ezinye iziphumo, njengokuqhuma kwesikhumba, kungenzeka zingabi nzima kodwa zingakhathaza. Ezinye iziphumo aziveli kuze kube ngeminyaka noma ngeminyaka ngemuva kokusetshenziswa kwale mithi. Ngaphambi kokuba uqale ukwelashwa nge-panitumumab, wena nodokotela wakho kufanele nixoxe ngezinzuzo zale mithi kanye nezingozi zokuyisebenzisa. Lolu dokotela uzonikezwa kuphela yi- noma ngaphansi kokunakekelwa okuqondile kudokotela wakho. Lo mkhiqizo uyatholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucatshangeni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqulu ozothatha wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluhlukile noma ukusabela okungokwe-allergy kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo ze-allergies, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele ezenziwe kuze kube yimanje azibonakalisi izinkinga ezikhethekile zezingane ezingalinda ukusetshenziswa kokubeka i-panitumumab kubantwana. Noma kunjalo, ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube yimanje azibonakalisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kokubeka i-panitumumab kubantu abadala. Noma kunjalo, abanye abantu abadala banesilinganiso esikhulu sokuba nemiphumela emibi engafunwa (isb., ukweluka), okungadinga ukuqapha kubantu abamukela le mithi. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungadingeka. Tshela ochwepheshe bakho bezempilo uma uthatha noma iyiphi enye imithi yokuqaphela noma engekho iresiphi (over-the-counter [OTC]). Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi noma eduze nesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka kube khona ukusebenzisana. Ukusebenzisa utshwala noma utshaba ngezinye izidakamizwa kungabangela ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Udokotela noma omunye umsebenzi wezempilo oqeqeshwe kahle uzokunika le miyekezo esibhedlela noma esikhungweni sokwelapha umdlavuza. Le miyekezo inikezwa ngenisipho elibekwe kwenye yezinsizi zakho. I-Panitumumab kufanele inikezwe kancane, ngakho-ke isipho kuzofanele sihlale sikhona okungenani isikhathi esingamahora. Le miyekezo ngezinye izikhathi ibangela ukuphefumula nokugabha. Noma kunjalo, kubalulekile kakhulu ukuthi uqhubeke uthola le miyekezo, ngisho noma uqala ukuzwa ubuhlungu. Buza udokotela wakho ngezindlela zokunciphisa le miphumela.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.