Panobinostat (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Farydak
Mayelana naleli khambi
I-Panobinostat isetyenziswa ndawonye ne-bortezomib ne-dexamethasone ukuze ikwelaphe abantu abane-multiple myeloma (umdlavuza weeseli ze-plasma) abake bamukele okungenani ukwelashwa okunye okungu-2. Lolu lwelapha luyatholakala kuphela ngomyalelo wezokwelapha. Lo mkhiqizo uyatholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Uma ukukhetha ukusebenzisa imithi, kufanele kuqhathaniswe ingozi yokusebenzisa imithi nezinzuzo ezizoletha. Lo ngumqulu ozowenza wena nodokotela wakho. Kule mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo olukhulu noma oluhambelanayo lwe-allergic kule mithi noma kwezinye izidakamizwa. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo ze-allergies, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubudlelwano bobudala nemiphumela ye-panobinostat kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-panobinostat kubantu abadala. Noma kunjalo, abantu abadala banamathuba amaningi okuba nemiphumela engathandeki, okungadinga ukuqapha nokulungiswa komthamo kwabaguli abamukela le mithi. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokusebenzisa le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo izidakamizwa ezimbili ezahlukene zingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma yimiphi imithi ehlwini elingezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo ayikhuthazwa. Udokotela wakho anganquma ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo ngokuvamile akusikhuthazwa, kodwa kungadingeka kwezinye izimo. Uma zombili izidakamizwa ziyalelwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uzisebenzisa kangaki enye noma zombili izidakamizwa. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungabangela ukuhlangana. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile akusikhuthazwa, kodwa kungangaphepheki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uzisebenzisa kangaki le mithi, noma akunikeze imiyalo ekhethekile yokusebenzisa ukudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi ebizwa ngokuthi ukwelapha umdlavuza inamandla kakhulu futhi ingaba nemiphumela eminingi emibi. Ngaphambi kokuthola le mithi, qiniseka ukuthi uyayiqonda yonke imingcele nezinzuzo. Kubalulekile ukuthi usebenzisane eduze nodokotela wakho ngesikhathi sokwelashwa kwakho. Thatha le mithi ngokuqondile njengoba uqondiswe yidokotela wakho. Ungayithathi ngaphezulu, ungayithathi kaningi, futhi ungayithathi isikhathi eside kunalokho oqondiswe yidokotela wakho. Imithi kufanele ifike ne-Medication Guide. Funda futhi ulandele lezi zinkomba ngokucophelela. Buza udokotela wakho noma umthengisi wemithi uma unemibuzo. Thatha le mithi ngesikhathi esifanayo nsuku zonke, ngokudla noma ngaphandle kokudla. Gwinya ikhaphsuli yonke ngekomityi lamanzi. Ungayivuli, ungayiqhekeza, ungayaphula, noma ungayikhinya. Qaphela ukungayiphathi ikhaphsuli eqhekeziwe noma ephukile. Uma uthinta ikhaphsuli ephukile noma eqhekeziwe, geza isikhumba sakho ngesepu namanzi acacile. Uma imithi ingena emehlweni akho, geza ngamanzi. Gwema ukudla i-grapefruit, insimbi yase-star, noma i-pomegranate nokupha i-grapefruit noma ijusi le-pomegranate ngenkathi usebenzisa le mithi. Uma uphuka ngemuva kokuthatha umthamo, ungayithathi enye ikhaphsuli. Linda bese uthatha umthamo wakho olandelayo ngesikhathi sakho esivamile. Umthamo wale mithi uzobahlukile kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela imithamo yale mithi. Uma umthamo wakho uhlukile, ungawushintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lemithi oyithatha lixhomeke emandleni emithi. Futhi, inani lemithamo oyithatha nsuku zonke, isikhathi esivunyelwe phakathi kwemithamo, nobude besikhathi oyithatha imithi kuxhomeke enkingeni yezokwelapha oyisebenzisela imithi. Uma uphuthelwa umthamo wale mithi, uthathe ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi somthamo wakho olandelayo, skip umthamo ophuthelwe bese ubuyela esimweni sakho sokuthola imithamo. Ungawandisi imithamo. Ungayithathi le mithi uma sekudlule amahora angaphezu kwe-12 kusukela uphuthelwe umthamo wakho wokugcina. Gcina kubantu abangabantwana. Ungagcini imithi eliphelile noma imithi engasadingeki. Buza ochwepheshe bezempilo ukuthi kufanele uyilahule kanjani imithi oyisebenzisayo. Gcina imithi esitsheni esivalekile ekushiseni kweqembu, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungayifrizi. Gcina iphakheji le-blister ebhokisini lokuqala ukuze uvikele ekukhanyeni.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.