Yini i-Papaverine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Papaverine iyimithi ephumuzayo yemisipha ebushelelezi esiza imithambo yegazi ukuthi yande futhi ithuthukise ukuhamba kwegazi emzimbeni wakho wonke. Le mithi kadokotela isebenza ngokuvimba iziteshi ezithile ze-calcium emisipheni yakho, okwenza imithambo yakho yegazi yande futhi kunciphise imisipha. Odokotela bavame ukunikeza i-papaverine ngezimo ezihilela ukujikeleza kwegazi okungahambi kahle, ikakhulukazi lapho imithambo yegazi iba mncane kakhulu noma ivaleke.

Yini i-Papaverine?

I-Papaverine ingeyomndeni wemithi ebizwa ngokuthi ama-vasodilators, okusho ukuthi isiza ukwandisa imithambo yakho yegazi. Le mithi ivela esitshalweni se-opium poppy, kodwa ngokungafani neminye imithi ethathwe ku-opium, i-papaverine ayinayo izakhiwo eziluthayo noma imiphumela yokunciphisa ubuhlungu. Kunalokho, igxila ngokuqondile ekuphumuleni kwemisipha ebushelelezi etholakala ezindongeni zemithambo yakho yegazi.

Uma uthatha i-papaverine, ihamba ngegazi lakho futhi iqondise emisipheni ezungeze imithambo yakho nemithambo. Lesi senzo esiqondiwe sisiza ukubuyisela ukuhamba kwegazi okuvamile ezindaweni zomzimba wakho ezingase zingatholi ukujikeleza okwanele.

Isetshenziselwani i-Papaverine?

I-Papaverine iphatha izimo ezihlukahlukene ezihlobene nokujikeleza kwegazi okungahambi kahle kanye nemisipha. Udokotela wakho angase anikeze le mithi uma imithambo yakho yegazi ingahambisi umoya-mpilo kanye nezakhamzimba ezanele ezingxenyeni ezithile zomzimba wakho.

Izimo ezivamile i-papaverine esiza ngazo zihlanganisa isifo semithambo esingaphandle, lapho imithambo emilenzeni yakho noma ezingalweni iba mncane. Ingasiza futhi ekwelapheni izinkinga ezithile zesigqi senhliziyo futhi isize ngezinkinga zokuhamba kwegazi ebuchosheni bakho noma kwamanye amalunga omzimba.

Nawa amanye amazwi i-papaverine evame ukuwalapha:

• Isifo semithambo yegazi esithinta izingalo noma imilenze yakho
• Ukungasebenzi kahle kwemithambo yegazi ebuchosheni okubangela ukuncipha kokugeleza kwegazi ebuchosheni bakho
• Ukuqina kwemithambo yegazi emathanjeni akho
• Ukuqina kwemisipha ebushelelezi emathunjini akho
• Ezinye izinhlobo zokungasebenzi kahle kwesitho sokuzala esihlobene nokugeleza kwegazi

Kwezinye izimo, odokotela bangase banikeze i-papaverine ngezimo ezingavamile njengesifo sikaRaynaud noma izinhlobo ezithile zekhanda elibangelwa ukuqina kwemithambo yegazi. Umhlinzeki wakho wokunakekelwa kwezempilo uzonquma ukuthi i-papaverine ilungele yini isimo sakho esithile.

Isebenza Kanjani I-Papaverine?

I-Papaverine isebenza ngokuvimba iziteshi ze-calcium emangqamuzaneni emisipha ebushelelezi yemithambo yakho yegazi. Lapho i-calcium ingakwazi ukungena kula mangqamuzana ngendlela efanele, imisipha iyakhululeka futhi imithambo yakho yegazi iyanda, ivumela ukuhamba kwegazi okungcono.

Cabanga ngemithambo yakho yegazi njengamashubhu engadi angase aqine noma akhululeke. Lapho i-papaverine isebenza, kufana nokukhulula ukubamba kulawo mashubhu, okuvumela igazi eliningi ukuthi ligeleze ngokukhululeka kuwo. Lokhu kuthuthukiswa kokujikeleza kwegazi kuletha umoya-mpilo omningi kanye nezakhamzimba ezicutshini ezizidingayo.

Umuthi uthathwa njengomuthi oqinile ngokulinganisela, okusho ukuthi ukhiqiza imiphumela ebonakalayo ngaphandle kokuba namandla ngokweqile. Ngokuvamile uzoqala ukuzwa izinzuzo zawo phakathi nemizuzu engama-30 kuya emahoreni amabili ngemva kokuwuthatha, nemiphumela ehlala amahora amaningi.

Kufanele Ngiyithathe Kanjani I-Papaverine?

Thatha i-papaverine ngendlela eqondile udokotela wakho ayala ngayo, ngokuvamile ngenkomishi yamanzi egcwele. Ungawuthatha lo muthi ngaphandle kokudla noma ngemva kokudla, nakuba ukuwuthatha nokudla kungasiza ekunciphiseni ukuquleka kwesisu uma uhlangabezana nanoma yikuphi ukuphatheka kabi kokugaya ukudla.

Abantu abaningi bathatha i-papaverine izikhathi ezi-3 kuya kwezi-4 ngosuku, behlukanisa imithamo ngokulinganayo usuku lonke. Zama ukuthatha imithamo yakho ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo omuthi ohlelweni lwakho.

Nansi indlela yokuthatha i-papaverine ngendlela efanele:

1. Gwinya ithebhulethi noma ikhaphule ngokugcwele ngamanzi amaningi
2. Ungayichobozi, uhlafune, noma uyiphule amafomula akhishwa kancane kancane
3. Thatha imithamo ngesikhathi esinqunyiwe phakathi nosuku
4. Uma uzwa isisu singahambi kahle, thatha nokudla okulula noma ubisi
5. Gwema utshwala ngenkathi usebenzisa lo muthi

Uma usebenzisa ifomu elikhishwa kancane kancane, kubaluleke kakhulu ukuthi ungalichobozi noma ulilumule, njengoba lokhu kungakhipha umuthi omningi ngesikhathi esisodwa. Njalo landela imiyalelo ethile kadokotela wakho, njengoba umthamo wakho ungahluka ngokuya ngesimo sakho nokuphendula ekwelashweni.

Kufanele Ngithathe I-Papaverine Isikhathi Esingakanani?

Ubude bokwelashwa nge-papaverine buyahluka ngokuya ngesimo sakho esithile nokuthi uphendula kahle kangakanani emuthini. Abanye abantu badinga ukwelashwa kwesikhashana okuthatha amasonto ambalwa, kanti abanye bangadinga ukwelashwa kwesikhathi eside.

Udokotela wakho uzoqapha inqubekela phambili yakho futhi alungise uhlelo lwakho lokwelashwa ngokufanele. Ezimweni eziphuthumayo njengama-muscle spasms, ungase udinge i-papaverine izinsuku ezimbalwa kuya emavikini ambalwa. Ngezinkinga zokujikeleza kwegazi ezingapheli, ukwelashwa kungaqhubeka izinyanga noma isikhathi eside.

Ungayeki ukuthatha i-papaverine ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe kungabangela ukuthi izimpawu zakho zibuye noma zibe zimbi, ikakhulukazi uma ubezithatha isikhathi eside.

Yiziphi Izimo Ezingezinhle Ze-Papaverine?

Njengayo yonke imithi, i-papaverine ingabangela imiphumela emibi, nakuba kungathi akubona bonke abantu abayitholayo. Imiphumela eminingi emibi imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Imiphumela emibi evame kakhulu ongase uyithole ihlanganisa isiyezi, ikhanda elibuhlungu, noma isisu esingahambi kahle. Lokhu kuvame ukwenzeka uma uqala ukuthatha umuthi noma uma umthamo wakho ukhuphuka.

Imiphumela emibi ejwayelekile ethinta abantu abaningi ihlanganisa:

• Isiyezi noma ukukhathala, ikakhulukazi uma usukuma
• Ukuqaqamba kwekhanda noma ukucindezela okuncane ekhanda
• Isicanucanu noma ukuphatheka kabi kwesisu
• Ukubomvu noma ukuzwa ufudumele
• Ukukhathala noma ukozela

Imiphumela emibi engavamile kodwa ebucayi idinga ukunakekelwa kwezokwelapha ngokushesha. Lokhu kufaka phakathi isiyezi esikhulu, ukuquleka, ukushaya kwenhliziyo okungajwayelekile, noma ubuhlungu obukhulu besisu. Nakuba kungavamile, abanye abantu bangase babe nokusabela komzimba okunezimpawu ezinjengokuqubuka, ukuvuvukala, noma ubunzima bokuphefumula.

Ngokuvamile, i-papaverine ingabangela izinkinga zesibindi noma izinguquko ezinkulu zesigqi senhliziyo. Udokotela wakho uzokuqapha ngezinkinga ezingaba khona, ikakhulukazi uma uthatha umuthi isikhathi eside.

Ubani Ongafanele Athathwe I-Papaverine?

I-Papaverine ayiphephile kuwo wonke umuntu, futhi izimo ezithile zezokwelapha noma imithi ingakwenza kungafaneleki kuwe. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyala lo muthi.

Akufanele uthathe i-papaverine uma unesifo sesibindi esibi, njengoba isibindi sakho sisebenzisa lo muthi. Abantu abanezimo ezithile zenhliziyo, ikakhulukazi labo abanokuvinjwa okuphelele kwenhliziyo, kufanele futhi bagweme i-papaverine.

Izimo ezingase zikuvimbele ukuthatha i-papaverine zifaka:

• Isifo sesibindi esibi noma ukwehluleka kwesibindi
• Ukuvinjwa okuphelele kwe-atrioventricular heart
• Ukungezwani okwaziwayo ne-papaverine noma imithi efanayo
• Umfutho wegazi ophansi kakhulu
• Izinhlobo ezithile ze-glaucoma

Xhumana nodokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa imithi yomfutho wegazi, imithi yenhliziyo, kanye nanoma yiziphi izithasiselo. Ezinye izinhlanganisela zingaba yingozi, ikakhulukazi ngemithi ephinde yehlise umfutho wegazi noma ethinte isigqi senhliziyo.

Amagama Omkhiqizo we-Papaverine

I-Papaverine itholakala ngaphansi kwamagama amaningi omkhiqizo, nakuba ivame ukuyalelwa njengomuthi ojwayelekile. Ifomu elivamile livame ukuba ngentengo ephansi futhi lisebenza ngempumelelo njengoba kwenza izinguqulo zegama lomkhiqizo.

Amanye amagama ajwayelekile emakethe ahlanganisa i-Pavabid, i-Cerespan, ne-Genabid, nakuba ukutholakala kwazo kuhluka ngendawo nangemithi. Udokotela wakho noma usokhemisi angakutshela ukuthi yiluphi uhlobo oluqondile noma inguqulo ejwayelekile abakubhalela yona.

Noma ngabe uthola i-papaverine yegama lomkhiqizo noma ejwayelekile, isithako esisebenzayo nokusebenza kahle kuhlala kufana. Umehluko omkhulu uvame ukuba kumumo wethebhulethi, umbala, noma izithako ezingasebenzi ezisetshenziswa ekukhiqizeni.

Ezinye izindlela ze-Papaverine

Imithi eminingi ehlukile ingelapha izimo ezifanayo ne-papaverine, kuye ngezidingo zakho ezithile. Udokotela wakho angase acabangele lezi ezinye izindlela uma i-papaverine ingakulungele noma uma ungasabeli kahle kuyo.

Ezinye izinto ezandisa imithambo yegazi njenge-pentoxifylline noma i-cilostazol zingaba ezinye izinketho zesifo semithambo esingaphandle. Ngezinhlungu zemisipha, imithi efana ne-cyclobenzaprine noma i-baclofen ingaba ezinye izindlela.

Ezinye izindlela zemithi udokotela wakho angase azicabangele zihlanganisa:

• I-Pentoxifylline yokuthuthukisa ukuhamba kwegazi
• I-Cilostazol yesifo semithambo esingaphandle
• I-Nifedipine yezinhlungu zemithambo yegazi
• I-Cyclobenzaprine yezinhlungu zemisipha
• I-Isoxsuprine ngezinkinga zokujikeleza kwegazi

Izindlela ezingezona zemithi njengokuzivocavoca njalo, ukuyeka ukubhema, kanye nezinguquko ekudleni nazo zingasiza ekuthuthukiseni ukujikeleza kwegazi. Udokotela wakho uzosebenza nawe ukuthola indlela engcono kakhulu yokwelapha isimo sakho esithile.

Ingabe i-Papaverine ingcono kune-Pentoxifylline?

Kokubili i-papaverine ne-pentoxifylline zisiza ekuthuthukiseni ukuhamba kwegazi, kodwa zisebenza ngezindlela ezehlukile kancane futhi zingase zifaneleke kangcono kubantu abahlukene. Akukho muthi owodwa ongcono kunomunye.

I-Papaverine iqondisa imisipha yemithambo yegazi, kuyilapho i-pentoxifylline ithuthukisa ukuhamba kwegazi ngokwenza amaseli abomvu egazi aguquguquke kakhulu. Udokotela wakho uzokhetha ngokusekelwe esimweni sakho esithile, eminye imithi oyithathayo, nokuthi ukubekezelela kahle kangakanani inketho ngayinye.

Abanye abantu basabela kangcono emuthini owodwa kunomunye, futhi ngezinye izikhathi odokotela bangase babhale kokubili ndawonye ukuze bathole inzuzo enkulu. Ukukhetha kuvame ukuncika emlandweni wakho wezokwelapha kanye nezinkinga ezithile zokujikeleza kwegazi ozibhekanayo.

Imibuzo Evame Ukubuzwa Mayelana ne-Papaverine

Q1. Ingabe i-Papaverine iphephile kubantu abanesifo sikashukela?

I-Papaverine ingaba iphephile kubantu abanesifo sikashukela, kodwa idinga ukuqashwa ngokucophelela. Isifo sikashukela sivame ukubangela izinkinga zokujikeleza kwegazi ukuthi i-papaverine ingasiza ukuzixazulula, kodwa umuthi ungase uhlangane neminye imithi yesifo sikashukela.

Udokotela wakho uzodinga ukuqapha amazinga akho kashukela egazini eduze lapho uqala i-papaverine, njengoba ngezinye izikhathi ingathinta i-glucose yegazi. Njalo yazisa umhlinzeki wakho wezempilo ngesifo sakho sikashukela nayo yonke imithi yesifo sikashukela oyithathayo.

Q2. Kufanele ngenzeni uma ngiphuzile i-Papaverine eningi ngengozi?

Uma ngengozi uthatha i-papaverine eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela ukwehla okuyingozi komfutho wegazi, isiyezi esikhulu, noma izinkinga zesigqi senhliziyo.

Ungazami ukuzelapha ngokweqile ngokuthatha umuthi omncane ngosuku olulandelayo. Funani ukunakekelwa kwezokwelapha ngokushesha, ikakhulukazi uma uhlangabezana nesiyezi esikhulu, ukuquleka, noma ubunzima bokuphefumula.

Q3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Papaverine?

Uma uphuthelwa umthamo we-papaverine, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe bese uqhubeka nohlelo lwakho lokulinganisa olujwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungabangela imiphumela emibi eyingozi. Uma uvame ukukhohlwa imithamo, cabanga ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi ukukusiza ukuthi uhlale emgwaqeni.

Q4. Ngingayeka nini ukuthatha i-Papaverine?

Misa ukuthatha i-papaverine kuphela uma udokotela wakho ekutshela ukuthi kuphephile ukwenza kanjalo. Ukuyeka kungazelelwe kungabangela ukuthi izimpawu zakho zibuye noma zibe zimbi kakhulu, ikakhulukazi uma ubuthatha amasonto amaningi noma izinyanga.

Udokotela wakho angase anciphise kancane kancane umthamo wakho ngokuhamba kwesikhathi kunokuyeka ngokuphazima kweso. Le ndlela yokunciphisa kancane kancane isiza ekuvimbeleni izimpawu zokuhoxisa futhi ivumela umzimba wakho ukuthi ujwayele kancane kancane.

Q5. Ngingayithatha i-Papaverine nemithi yokwehlisa umfutho wegazi?

I-Papaverine ingathathwa neminye imithi yokwehlisa umfutho wegazi, kodwa le nhlanganisela idinga ukuqapha okucophelelayo. Zombili izinhlobo zemithi zinganciphisa umfutho wegazi, ngakho ukuzithatha ndawonye kungase kubangele ukuthi umfutho wegazi lakho wehle kakhulu.

Udokotela wakho cishe uzoqala ngemithamo ephansi futhi aqaphe umfutho wegazi lakho eduze uma udinga yomibili imithi. Ungalokothi ulungise imithi yakho yomfutho wegazi ngokwakho lapho uqala noma uyeka i-papaverine.