Yini i-Peanut Allergen DNFP (Indlela yomlomo): Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Peanut allergen DNFP iyimithi kadokotela eyenzelwe ukusiza ukunciphisa ukusabela okukhulu komzimba kuma-peanut ezinganeni nakubantu abasha. Lokhu kwelashwa okusha kusebenza ngokwembula kancane kancane amasosha omzimba akho ezingxenyeni ezincane, ezilawulwayo ze-peanut protein, okusiza umzimba wakho ukuthi ungabe usasabela ngokuhamba kwesikhathi.

Uma ungumzali wengane enokungezwani komzimba kuma-peanut, cishe ube neminyaka eminingi ufunda amalebula ezithako futhi uphethe imithi ephuthumayo. Le ndlela entsha inikeza ithemba lokunciphisa ukwesaba nokukhathazeka okuvame ukuhambisana nokuphatha ukungezwani komzimba okukhulu kokudla ekuphileni kwansuku zonke.

Yini i-Peanut Allergen DNFP?

I-Peanut allergen DNFP yindlela yokwelapha ngomlomo equkethe ufulawa we-peanut protein ojwayelekile. Umuthi uza ngama-capsule angavulwa futhi axutshwe nokudla, okwenza kube lula ezinganeni ukuwuthatha ngokuphepha.

Lokhu kwelashwa kumelela ukwelashwa kokuqala okuvunywe yi-FDA okwenzelwe ngqo ukunciphisa ubukhulu bokungezwani komzimba kuma-peanut. Cabanga ngakho njengendlela elawulwa ngokucophelela yokuqeqesha amasosha omzimba wakho ukuthi angabi nolaka lapho ehlangana nama-peanut proteins.

Umuthi awelaphi ukungezwani komzimba kuma-peanut, kodwa ungalinciphisa kakhulu ingozi yokusabela okukhulu ekuvezweni ngengozi. Imindeni eminingi ithola ukuthi lokhu kudala inethiwekhi yokuphepha enengqondo evumela ukuphila kwansuku zonke okungakhawulelwe kakhulu.

Yini i-Peanut Allergen DNFP Esetshenziselwa Yona?

Lo muthi uvunyelwe ngokuqondile izingane nentsha eneminyaka yobudala engu-4 kuya ku-17 abane-peanut allergies eqinisekisiwe. Umgomo oyinhloko ukunciphisa ubukhulu bokungezwani komzimba okungenzeka ngenxa yokuvezwa ngengozi kuma-peanut.

Uchwepheshe wezingane zakho we-allergy ngokuvamile uzoncoma lokhu kwelashwa uma benomlando wokuphendula okukhulu kwamantongomane kanye nokuhlolwa kwe-allergy okuhle. Ukwelashwa kusebenza kahle kakhulu uma kuqala ezindaweni zomtholampilo ezilawulwayo lapho ochwepheshe bezokwelapha bengaqapha kahle impendulo yengane yakho.

Kubalulekile ukuqonda ukuthi lokhu kwelashwa akuthathi indawo yezidakamizwa eziphuthumayo njenge-epinephrine auto-injectors. Kunalokho, kusebenza kanye nohlelo lwakho olukhona lokuphatha i-allergy ukuhlinzeka ngesendlalelo esengeziwe sokuvikela.

Isebenza Kanjani I-Peanut Allergen DNFP?

Lo muthi usebenza ngenqubo ebizwa ngokuthi i-oral immunotherapy, ebuyisela kancane kancane impendulo yamasosha omzimba wakho kumaprotheni amantongomane. Ukwelashwa kuqala ngemithamo emincane kakhulu eyanda kancane kancane ezinyangeni eziningi.

Amasosha omzimba wakho ngokuvamile aphendula ngokweqile kumaprotheni amantongomane ngokukhipha amakhemikhali abangela izimpawu ze-allergy. Ngokwembula umzimba wakho ezingxenyeni ezincane, ezilawulwayo njalo, umuthi usiza ukunciphisa lokhu kuphendula ngokweqile kancane kancane nangokuphepha.

Lokhu kuthathwa njengendlela yokwelapha enamandla aphakathi nendawo edinga ukugadwa ngokucophelela kwezokwelapha. Le nqubo ithatha ukubekezela nokuzibophezela, kodwa imindeni eminingi ibona ukuthuthuka okukhulu ekubekezeleleni kwengane yabo ukuchayeka ngengozi kwamantongomane ngemva kokuqeda iphrothokholi yokwelapha ephelele.

Kufanele Ngiyithathe Kanjani I-Peanut Allergen DNFP?

Lo muthi kufanele ngaso sonke isikhathi uthathwe ngendlela enqunywe ngayo nguchwepheshe wakho we-allergy, futhi imithamo yokuqala kufanele inikezwe endaweni yezokwelapha ehlomele ukubhekana nokuphendula kwe-allergy. Ukwelashwa ngokuvamile kuqala ngesigaba sokukhuphuka komthamo oqashwe ngokucophelela.

Amakhaphula angavulwa futhi okuqukethwe kuxutshwe nenani elincane lokudla okuthambile njenge-applesauce, iyogathi, noma i-pudding. Qiniseka ukuthi ukudla kusezingeni lokushisa legumbi noma kupholile, njengoba ukushisa kungathinta ukusebenza komuthi.

Ingane yakho kufanele ithathe imithi esiswini esingenalutho, bese ilinda okungenani amahora angu-2 ngaphambi kokudla. Lesi sikhathi sisiza ekuqinisekiseni ukumuncwa okufanele futhi sinciphisa ubungozi bemiphumela emibi. Njalo yiba nemithi ephuthumayo etholakalayo ngesikhathi sokwelashwa.

Ukuzivocavoca umzimba kufanele kugwenywe amahora amaningana ngemva kokuthatha umthamo ngamunye, njengoba ukuzivocavoca kungakhuphula ubungozi bokungezwani komzimba. Udokotela wakho uzohlinzeka ngemihlahlandlela ethile mayelana nemikhawulo yomsebenzi ngokusekelwe ezidingweni zomuntu ngamunye zengane yakho.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Peanut Allergen DNFP?

Ukwelashwa ngokuvamile kuhilela isigaba sokuqala sokukhuphuka komthamo esingathatha izinyanga eziningana, kulandelwe isigaba sokugcinwa lapho ingane yakho iqhubeka nokuthatha umthamo ozinzile nsuku zonke. Inqubo yonke ngokuvamile ithatha okungenani izinyanga eziyi-10-12 ukuze iqede.

Uchwepheshe wakho we-allergist uzoqapha ukuqhubeka kwengane yakho ngokuhlolwa okuvamile futhi angashintsha umugqa wesikhathi ngokusekelwe ekutheni bayakubekezelela kangakanani ukwelashwa. Ezinye izingane zingase zidinge izikhathi ezide ukuze zifinyelele umthamo wazo wokugcinwa okuhlosiwe ngokuphepha.

Ngemva kokuqeda inqubo yokwelashwa ephelele, imindeni eminingi iyaqhubeka nemithamo yokugcinwa eqhubekayo ukuze igcine izinzuzo zokuvikela. Udokotela wakho uzoxoxa ngokuhlela isikhathi eside ngokusekelwe ekuphenduleni okuthile kwengane yakho kanye nobukhulu bokungezwani komzimba.

Yiziphi Imiphumela Emibi ye-Peanut Allergen DNFP?

Njengoba le mithi ngamabomu yembula ingane yakho ku-allergen yayo, eminye imiphumela emibi ilindelekile futhi empeleni ikhombisa ukuthi ukwelashwa kuyasebenza. Imiphumela eminingi emibi imnene futhi ilawuleka ngesiqondiso esifanele sezokwelapha.

Imiphumela emibi evame kakhulu ongase uyibone ihlanganisa ukungakhululeki kwesisu okuncane, isicanucanu, noma ukucasuka komphimbo. Lezi zimpawu ngokuvamile zenzeka emahoreni ambalwa okuqala ngemva kokuthatha imithi futhi ngokuvamile zithuthuka njengoba umzimba wengane yakho uzivumela ekwelashweni.

Imiphumela emibi ekhathazayo ingabandakanya imihuzuko, ubunzima bokugwinya, noma izinkinga zokuphefumula. Nakuba lokhu kungavamile, kudinga ukunakekelwa kwezokwelapha ngokushesha futhi kungase kubonise isidingo sokulungiswa komthamo noma ukuguqulwa kokwelashwa.

Nawa imiphumela emibi okufanele uyibheke, uqala ngaleyo evame kakhulu:

• Ubuhlungu obuncane besisu noma ukuqaqamba
• Ukucanuzela kwenhliziyo noma ukuhlanza
• Ukulunywa komphimbo noma ukucasuka okuncane
• Ukuphendula kwesikhumba njengamathumba amancane noma ukuluma
• Ukukhwehlela noma ukukhwehlela
• Ikhanda elibuhlungu noma ukukhathala

Ukuphendula okungathi sína kodwa okungavamile kubandakanya ubuhlungu obukhulu besisu, ukuhlanza okuqhubekayo, noma izimpawu ze-anaphylaxis njengobunzima bokuphefumula, ukuvuvukala kobuso noma umphimbo, noma imihuzuko emibi yomzimba wonke. Lezi zimpawu zidinga ukunakekelwa kwezokwelapha eziphuthumayo ngokushesha.

Imiphumela emibi engavamile kodwa engathi sína ingabandakanya i-eosinophilic esophagitis, isimo lapho amaseli athile omzimba akha khona e-esophagus okubangela ubunzima bokugwinya. Udokotela wakho uzoqapha lesi simo ngokuhlolwa okuvamile nokulandela izimpawu.

Ubani Ongafanele Athathe I-Peanut Allergen DNFP?

Lokhu kwelashwa akulungelwe wonke umuntu onezinto ezingezwani namantongomane. Izingane ezinemibandela ethile yezokwelapha noma labo abathatha imithi ethile kungenzeka bangabi ngabazongenela ukwelashwa ngomlomo.

Ingane yakho akufanele isebenzise lo muthi uma inesifuba esingalawuleki kahle, njengoba ukwelashwa kungase kwenze izinkinga zokuphefumula zibe zimbi. I-eosinophilic esophagitis esebenzayo noma ezinye izifo ze-eosinophilic gastrointestinal nazo zenza lokhu kwelashwa kungafaneleki.

Izingane eziye zaba nokuphendula okukhulu, okusongela impilo ezintweni ezincane kakhulu zamantongomane kungenzeka zingabi ngabazongenela ekuqaleni. Udokotela wakho wezinto ezingezwani nezinto ezithile uzohlola ngokucophelela umlando wokungezwani kwengane yakho nezimo zempilo zamanje ngaphambi kokuncoma lokhu kwelashwa.

Lezi zimo ezilandelayo ngokuvamile zenza lokhu kwelashwa kungafaneleki:

• Isifuba esingalawuleki noma ukuhlaselwa kwe-asthma okuvamile
• I-eosinophilic esophagitis esebenzayo noma izimo ezifanayo
• Isifo senhliziyo esibi kakhulu
• Ukusetshenziswa kwamanje kwemithi ethile efana ne-ACE inhibitors
• Umlando we-anaphylaxis enkulu ezinanini ezincane kakhulu zamantongomane
• Ukungakwazi ukugwema umsebenzi womzimba ngemva kokuthatha umthamo

Uchwepheshe wakho we-allergist uzobuye acabangele izinto ezinjengokuthi umndeni wakho uyakwazi yini ukulandela inqubo yokwelapha eqinile nokufinyelela ekunakekelweni kwezempilo eziphuthumayo lapho enquma ukuthi le mithi ilungele ingane yakho.

Igama Lomkhiqizo Le-Peanut Allergen DNFP

Le mithi ithengiswa ngaphansi kwegama lomkhiqizo elithi Palforzia, elenziwa yi-Aimmune Therapeutics. Yiyona yokuqala futhi okwamanje kuphela ukwelashwa kwe-oral immunotherapy okuvunywe yi-FDA okwenzelwe ngqo ukungezwani komzimba namantongomane.

I-Palforzia iza ngamandla ahlukene amaphilisi ahambisana nezigaba ezihlukene zokwelashwa. Ukupakishwa kwenzelwe ukukusiza wena nethimba lakho lezempilo ukuthi nilandelele ukuqhubeka emazingeni ahlukene omthamo ngokuphepha.

Ikhemisi lakho cishe lizodinga uku-oda ngokukhethekile le mithi, njengoba ingagcinwa ngokujwayelekile. Ukwelashwa kudinga inethiwekhi yekhemisi ekhethekile kanye nezimo ezithile zokugcina ukuze kugcinwe ukusebenza kahle komuthi.

Ezinye Izindlela Zokwelapha I-Peanut Allergen DNFP

Njengamanje, azikho ezinye izindlela zokwelapha ze-oral immunotherapy ezivunywe yi-FDA ezikhethekile zokungezwani komzimba namantongomane. Kodwa-ke, abanye ochwepheshe be-allergist bangase banikeze ukwelashwa okufanayo ngokusebenzisa izivivinyo zemitholampilo noma ukusetshenziswa ngaphandle kwelebula kwamalungiselelo amaprotheni amantongomane.

Izindlela zokulawula ukungezwani komzimba zendabuko zihlala ziyizindlela ezibalulekile, okuhlanganisa ukugwema ngokuqinile amantongomane, ukuthwala imithi ephuthumayo, nokusebenza nochwepheshe be-allergist ukuthuthukisa izinhlelo eziphelele zokwenza izinto ezingalindelekile.

Eminye imindeni ihlola ezinye izindlela zokwelapha ngomzimba ezifana ne-epicutaneous immunotherapy (i-patch therapy) ngokusebenzisa izivivinyo zomtholampilo. Ucwaningo luqhubeka ngezindlela ezihlukahlukene zokusiza amasosha omzimba ukuthi angasabela kakhulu kuma-allergen okudla.

Amanye amaqhinga okuphatha afaka ukusebenza nodokotela bezokudla abangochwepheshe ekuguleni okubangelwa ukudla, ukujoyina amaqembu okusekela imindeni ephethe ukungezwani okukhulu, nokuhlala unolwazi mayelana nokwelashwa okusha ngezinhlangano zokungezwani komzimba.

Ingabe i-Peanut Allergen DNFP ingcono kune-Traditional Avoidance?

Lo muthi unikeza indlela ehlukile kunokuba

Udokotela wakho wezifo zokungezwani komzimba uzohlola ngokucophelela ukulawulwa komoya wezingane zakho kanye nomsebenzi wamaphaphu ngaphambi kokuqala ukwelashwa. Bangase badinge ukuthuthukiswa kwemithi ye-asthma kanye nokubonisa amaphethini okuphefumula azinzile ezinyangeni eziningana ngaphambi kokuqala ukwelashwa ngomlomo.

Kuyo yonke inkathi yokwelashwa, i-asthma yengane yakho izoqashwa ngokucophelela, futhi ukwelashwa ngomlomo kungase kudingeke ukuthi kumiswe noma kumiswe uma izimpawu ze-asthma ziba zimbi. Ukuba nohlelo olusha lokusebenza lwe-asthma kubalulekile ekwelashweni okuphephile.

Kufanele Ngenzeni Uma Ngiphuthelwa Ngengozi Ukunikeza I-Peanut Allergen DNFP Eningi Kakhulu?

Uma ngengozi unikeza okungaphezu komthamo obekiwe, xhumana nodokotela wezingane zakho ngokushesha futhi uziqaphele ngokucophelela izimpawu zokungezwani komzimba. Ungalindi ukubona ukuthi izimpawu ziyavela ngaphambi kokufuna isiqondiso sezokwelapha.

Gcina imithi yakho ephuthumayo itholakala kalula futhi ulungele ukuyisebenzisa uma ingane yakho ithuthukisa izimpawu ezinjengobunzima bokuphefumula, ubuhlungu obukhulu besisu, noma izinduna ezisabalale kabanzi. Ngisho nokweqisa okuncane kungase kubangele ukusabela okukhulu kunokujwayelekile.

Udokotela wakho angase ancome ukuletha ingane yakho esikhungweni sezokwelapha ukuze ibhekwe, ikakhulukazi uma ukweqisa kwakubalulekile noma uma ingane yakho inomlando wokungezwani okukhulu. Kuhlale kungcono ukuqapha uma ubhekene nokusabela okungenzeka kokungezwani komzimba.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Peanut Allergen DNFP?

Xhumana nodokotela wakho wezifo zokungezwani komzimba ngaphambi kokunikeza umthamo olandelayo uma uphuthelwa umthamo ohleliwe, ikakhulukazi uma sekudlule izinsuku ezimbalwa. Ukuphuthelwa imithamo kunganciphisa ukubekezelelana kwengane yakho futhi kungenzeka ukuthi kwandise ingozi yokusabela emithamini elandelayo.

Udokotela wakho angase ancome ukuqala kabusha ngomthamo ophansi noma ukwelula isikhathi phakathi kwemithamo ukuze kuqinisekiswe ukuphepha. Indlela ethile incike ekutheni sekudlule isikhathi esingakanani kusukela kumthamo wokugcina nokuthi ingane yakho ikuphi ohlelweni lwayo lokwelashwa.

Ungaphindi kabili imithamo ukuze ulungise leyo oyiphuthelwe, ngoba lokhu kungakhuphula kakhulu ingozi yokuba nezimpawu zokungezwani komzimba ezinzima. Ukuqina ekuthathweni kwemithi kubalulekile ekugcineni izinzuzo zokuvikela zokwelashwa ngokuphepha.

Ngingayeka nini ukuthatha i-Peanut Allergen DNFP?

Isinqumo sokuyeka ukwelashwa kufanele senziwe ngaso sonke isikhathi ngokubonisana nodokotela wakho we-allergist, ngokuvamile ngemva kokuqeda inqubo ephelele yokwelashwa futhi uzuze umthamo wokulondoloza ozinzile. Eminye imindeni ikhetha ukuqhubeka nemithamo yokulondoloza isikhathi eside ukuze igcine izinzuzo.

Udokotela wakho uzocabangela izinto ezinjengempendulo yengane yakho ekwelashweni, ikhono labo lokubekezelela ukuchayeka ngengozi, kanye nezintandokazi zomndeni wakho lapho kuxoxwa ngokuyeka. Akukho uhlu lwesikhathi olujwayelekile olusebenza kuyo yonke ingane.

Uma uyeka ukwelashwa, kubalulekile ukuqonda ukuthi ukubekezelela kwengane yakho okukhulu kungancipha kancane kancane ngokuhamba kwesikhathi. Uzodinga ukugcina imikhuba yokugwema ngokucophelela futhi uqhubeke nokuthwala imithi esheshayo njengoba kunconywe yi-allergist yakho.

Ingabe ingane yami ingadla ama-peanut ngokukhululeka ngemva kokuqeda ukwelashwa?

Cha, ukuqeda ukwelashwa ngomlomo akusho ukuthi ingane yakho ingadla ama-peanut ngokukhululeka noma ukuthi ukungezwani komzimba kwayo kuphulukisiwe. Ukwelashwa kuklanyelwe ukuhlinzeka ngokuqapha ngokumelene nokuchayeka ngengozi, hhayi ukuvumela ukusetshenziswa ngamabomu kwama-peanut.

Ingane yakho kufanele iqhubeke nokugwema ama-peanut ekudleni kwayo okuvamile futhi igcine zonke izinyathelo zokuphepha njengokufunda amalebula nokuthwala imithi esheshayo. Ukwelashwa kunikeza inethiwekhi yokuphepha, kodwa ukugwema ama-peanut kuhlala kuyisu eliyinhloko lokuvimbela ukusabela.

Ezinye izingane zingase zikwazi ukubekezelela ama-peanut amancane ngemva kokwelashwa, kodwa lokhu kufanele kunqunywe futhi kuqondiswe yi-allergist yakho ngokuhlola ngokucophelela. Ungalokothi ucabange ukuthi ingane yakho ingadla ama-peanut ngokuphepha ngaphandle kwesiqondiso sezokwelapha esiqondile.