Yini i-Perphenazine ne-Amitriptyline: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Perphenazine ne-amitriptyline iyinhlanganisela yemithi ehlanganisa imithi emibili enamandla yezifo zengqondo epilini elilodwa. Le mithi ihlanganisa i-perphenazine (i-antipsychotic) ne-amitriptyline (i-tricyclic antidepressant) ukusiza ukwelapha izimo ezithile zempilo yengqondo ngempumelelo enkulu kunomuthi ngamunye uwedwa.

Udkt wakho angase akubhalele le nhlanganisela uma ubhekene nezimo ezihilela zombili izimpawu zemizwa kanye nezinye izinkinga zengqondo. Ilusizo ikakhulukazi kubantu abadinga izinzuzo zemithi yomibili kodwa abafuna ukuthatha iphilisi elilodwa esikhundleni sezimbili ezihlukene.

Isetshenziselwani i-Perphenazine ne-Amitriptyline?

Le nhlanganisela yemithi ikakhulukazi ibhalelwe ukwelapha ukucindezeleka okwenzeka kanye nezimpawu ze-psychotic. Lezi zimpawu zingase zihlanganise ukuzwa amazwi, ukubona izinto ezingekho, noma ukuba nemicabango ezizwa ingaxhunyiwe eqinisweni.

Udkt wakho angase futhi acabangele le mithi uma unokucindezeleka okukhulu okungazange kuphendule kahle kwezinye izindlela zokwelapha. Ngezinye izikhathi, lapho ukucindezeleka kuyinselele ekhethekile ukuphatha, inhlanganisela yale mithi emibili inganikeza impumuzo lapho imithi eyodwa ingasebenzi.

Kwezinye izimo, abahlinzeki bezempilo basebenzisa le nhlanganisela ekwelapheni izifo zokukhathazeka ezinzima eziza nezimpawu zokucindezeleka. Ingxenye ye-perphenazine isiza ukuthulisa imicabango ekhulu, kuyilapho i-amitriptyline ibhekana nezinkinga zemizwa eziyisisekelo.

Isebenza kanjani i-Perphenazine ne-Amitriptyline?

Le mithi isebenza ngokugxila ezinhlelweni ezimbili ezihlukene ebuchosheni bakho ezithinta imizwa nokucabanga. Ingxenye ye-perphenazine ivimba ama-receptor athile e-dopamine, okusiza ukunciphisa izimpawu ze-psychotic njengokucabanga okungahlelekile noma ukucabanga okungahlelekile.

Ngesikhathi esifanayo, ingxenye ye-amitriptyline yandisa amazinga e-serotonin kanye ne-norepinephrine ebuchosheni bakho. Lawa amakhemikhali emvelo asiza ukulawula imizwa yakho, ukulala, kanye nomuzwa wakho wokuzinza.

Lokhu kuthathwa njengomuthi oqinile ophakathi nendawo wezengqondo ngoba uthinta amasistimu amaningi obuchopho ngesikhathi esisodwa. Indlela yokuhlanganisa ingasebenza kahle kakhulu kunokusebenzisa noma yimuphi umuthi ngawodwa, kodwa futhi idinga ukuqashwa ngokucophelela ngumhlinzeki wakho wezempilo.

Kufanele Ngiyithathe Kanjani I-Perphenazine kanye ne-Amitriptyline?

Thatha lo muthi njengoba nje udokotela wakho ekuyala, ngokuvamile kanye noma kabili ngosuku ngokudla. Ukuwuthatha ngokudla kusiza ukunciphisa isisu esibuhlungu futhi kusiza umzimba wakho ukuba umunce umuthi ngokulinganayo.

Ungawuthatha lo muthi ngamanzi, ubisi, noma ijusi. Ukuwuthatha ngobisi kungase kube mnene esiswini sakho uma uzwela emithini. Gwema utshwala ngokuphelele ngenkathi uthatha lo muthi, njengoba kungandisa ukozela neminye imiphumela emibi kakhulu.

Zama ukuthatha imithamo yakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqinile ohlelweni lwakho. Abantu abaningi bakuthola kuwusizo ukuthatha umthamo wabo kusihlwa ngoba lo muthi ungabangela ukozela, okungase empeleni kusize ngokulala.

Uma usanda kuqala lo muthi, udokotela wakho cishe uzoqala ngomthamo ophansi bese uwunyusa kancane kancane. Le ndlela isiza umzimba wakho ukuba uzivumelanise futhi inciphisa ithuba lokuba nemiphumela emibi ekhathazayo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Perphenazine kanye ne-Amitriptyline?

Ubude bokwelashwa buhluka kakhulu kumuntu nomuntu, kuye ngesimo sakho esithile nokuthi usabela kahle kangakanani emuthini. Abanye abantu bangase badinge le nhlanganisela izinyanga eziningana, kanti abanye bangazuza ekwelashweni kwesikhathi eside.

Udktora wakho uzohlola njalo ukuthi wenza kanjani futhi angase ashintshe uhlelo lwakho lokwelashwa ngokufanele. Kubalulekile ukuqhubeka nokuthatha imithi ngisho noma uqala ukuzizwa ungcono, ngoba ukuyeka ngaphambi kwesikhathi kungabangela ukuthi izimpawu zibuye.

Ungalokothi uyeke ukuthatha lo muthi kungazelelwe ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa futhi kungenza izimpawu zakho zokuqala zibe zimbi kakhulu. Umhlinzeki wakho wezempilo uzokwenza isimiso sokunciphisa kancane kancane uma udinga ukuyeka imithi.

Yiziphi Izimo Ezingezinhle Zomuthi i-Perphenazine ne-Amitriptyline?

Njengayo yonke imithi, le nhlanganisela ingabangela imiphumela engemihle, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi uzizwe ulungiseleleke kakhulu futhi wazi ukuthi ungangena nini kumhlinzeki wakho wezempilo.

Imiphumela engemihle ejwayelekile ongase uyibone ihlanganisa ukozela, isiyezi, umlomo owomile, nokuqunjelwa. Le miphumela ivame ukuba mncane futhi ivame ukuthuthuka njengoba umzimba wakho uzivumela emuthini emasontweni ambalwa okuqala.

Nansi imiphumela engemihle evame kakhulu abantu abayitholayo:

• Ukozela noma ukuzizwa ulele emini
• Isiyezi, ikakhulukazi lapho usukuma ngokushesha
• Umlomo owomile nokwanda komzwelo wokoma
• Ukuqunjelwa noma izinguquko ekuhambeni kwamathumbu
• Ukubona okungacacile noma ubunzima bokugxila
• Ukukhuluphala ngokuhamba kwesikhathi
• Ukukhuphuka kwesifiso sokudla

Le miphumela engemihle evamile ivame ukulawuleka futhi ivame ukungabonakali njengoba umzimba wakho uzivumela emuthini.

Abanye abantu bangase bathole imiphumela engemihle ekhathazayo edinga ukunakekelwa kwezempilo ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukwazi ukuze ukwazi ukufuna usizo uma kudingeka.

Xhumana nodokotela wakho ngokushesha uma uthola noma yimiphi yale miphumela engathi sína:

• Isiyezi esikhulu noma ukuquleka
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ukuqina kwemisipha okukhulu noma ukuthuthumela
• Umkhuhlane omkhulu nokujuluka
• Ukudideka okukhulu noma ukucasuka
• Ukungakwazi ukugwinya noma ukuphefumula
• Ukuphuzi kwesikhumba noma amehlo

Lezi zimpawu, nakuba zingavamile, zingabonisa ukusabela okungathi sína okudinga ukuhlolwa nokwelashwa ngokushesha.

Kukhona nemiphumela emibi engavamile kodwa engase ibe yingozi eyenzeka kubantu abangaphansi kuka-1% abathatha lo muthi. Lokhu kuhlanganisa i-tardive dyskinesia (ukuhamba kwemisipha okungazithandeli), i-neuroleptic malignant syndrome (ukusabela okusongela impilo), nokusabela okukhulu komzimba.

Ubani Ongafanele Athathe i-Perphenazine ne-Amitriptyline?

Lo muthi awulungele wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuwunika. Izimo nezimo ezithile zenza le nhlanganisela ibe yingozi noma ingasebenzi kahle.

Akufanele uthathe lo muthi uma njengamanje uthatha noma usanda kuthatha ama-MAO inhibitors (uhlobo lwe-antidepressant). Le nhlanganisela ingabangela umfutho wegazi ophezulu ngokuyingozi nezinye izinkinga ezingathi sína.

Abantu abanezimo ezithile zenhliziyo badinga ukugwema lo muthi ngokuphelele. Uma ube nesifo senhliziyo esisanda kwenzeka, izinkinga ezinkulu zokushaya kwenhliziyo, noma ukuvinjelwa kwenhliziyo, le nhlanganisela ingase iqhubekisele phambili isimo sakho senhliziyo.

Udokotela wakho uzoba nokuqapha okwengeziwe mayelana nokunika lo muthi uma unezimo ezilandelayo:

• I-Glaucoma noma ukwanda kwengcindezi yamehlo
• I-prostate enwetshiwe noma izinkinga zokugcinwa komchamo
• Isifo sesibindi esibi kakhulu
• Ukuphazamiseka kokuthuthumela noma isithuthwane
• Isifo sikaParkinson
• Izinkinga ze-thyroid
• Isifo sikashukela

Lezi zimo akudingeki zikuvimbele ekuthathweni komuthi, kodwa zidinga ukuqapha ngokucophelela futhi mhlawumbe kulungiswe umthamo.

Ukukhulelwa nokuncelisa kufuna ukucatshangelwa okukhethekile ngalo muthi. Nakuba kungavunyelwe ngokuzenzakalelayo, udokotela wakho uzoqaphela izinzuzo ezingaba khona uma ziqhathaniswa nezingozi ezingase zibe khona kuwe nomntwana wakho.

Amagama Omkhiqizo we-Perphenazine kanye ne-Amitriptyline

Igama elivame kakhulu lomkhiqizo ngalo muthi ohlanganisiwe yi-Triavil, nakuba itholakala njenge-Etrafon kwezinye izifunda. Lawa magama omkhiqizo aqukethe izithako ezisebenzayo ezifanayo ezingxenyeni ezifanayo njengoba kunjalo ezinguqulweni ezivamile.

I-pharmacy yakho ingase ikhiphe igama lomkhiqizo noma inguqulo evamile, kuye ngokuthi umshwalense wakho uhlanganisa ini nokutholakala. Zombili lezi zinguqulo zisebenza ngendlela efanayo futhi ziqukethe izithako ezisebenzayo ezifanayo.

Umuthi uza ngezinhlanganisela zamandla ahlukene, ngokuvamile eziqashelwa njengezilinganiso ze-perphenazine/amitriptyline njenge-2mg/10mg, 2mg/25mg, noma 4mg/25mg. Udokotela wakho uzoqaphela ukuthi yimaphi amandla alungele izidingo zakho ezithile.

Ezinye izindlela ze-Perphenazine kanye ne-Amitriptyline

Uma le nhlanganisela ingasebenzi kahle kuwe noma idala imiphumela engathandeki, udokotela wakho unezinye izindlela eziningana okufanele azicabangele. Ukukhetha kuncike ezimpawini zakho ezithile nokuthi usabele kanjani kweminye imithi.

Enye indlela ukuthatha i-perphenazine kanye ne-amitriptyline njengemithi ehlukene esikhundleni sepilisi ehlanganisiwe. Le ndlela ivumela udokotela wakho ukuthi alungise umuthi ngamunye ngokuzimela, okungasiza ekutholeni ibhalansi efanele.

Ezinye izinhlanganisela ze-antipsychotic kanye ne-antidepressant zingase zisebenze kangcono kwabanye abantu. Udokotela wakho angase acabange ukuhlanganisa i-antipsychotic ehlukile njenge-risperidone noma i-olanzapine ne-antidepressant ehlukile njenge-sertraline noma i-escitalopram.

Ezimweni ezithile, imithi emisha ye-antipsychotic yodwa ingase yanele. Imithi efana ne-aripiprazole noma i-quetiapine ngezinye izikhathi ingabhekana nezimpawu zokuziphatha ezingavamile nezokucindezeleka ngaphandle kokudinga i-antidepressant ehlukile.

Ingabe i-Perphenazine ne-Amitriptyline Ingcono Kunezithako Zokwelapha Ezihlukene?

Iphilisi elihlanganisiwe linikeza ukulula futhi mhlawumbe ukunamathela okungcono emithini ngoba udinga kuphela ukukhumbula umuthi owodwa esikhundleni semibili. Lokhu kungaba usizo ikakhulu uma ulawula izimo zempilo eziningi noma unzima ukulandela amaphilisi ahlukahlukene.

Nokho, ukuthatha imithi ngokuhlukana kunikeza udokotela wakho ukuguquguquka okwengeziwe ekulungiseni imithamo. Uma udinga okuningi kwesinye isithako kunomunye, amaphilisi ahlukene avumela ukulungiswa okuningi kwemithamo enembile.

Abanye abantu bathola ukuthi inhlanganisela ezinzile isebenza kahle ngezidingo zabo, kanti abanye benza ngcono ngemithamo eyodwa yesithako ngasinye. Udokotela wakho uzosiza ekunqumeni ukuthi iyiphi indlela engasebenza kahle esimweni sakho esithile.

Ukuphumelela kuncike kakhulu ekuphenduleni kwakho komuntu ngamunye emithini nasezimpawini zakho ezithile. Akukho ngisho nendlela eyodwa engcono ngokujwayelekile, futhi okusebenza kahle kakhulu kuyahlukahluka kumuntu nomuntu.

Imibuzo Evame Ukubuzwa Mayelana ne-Perphenazine ne-Amitriptyline

Ingabe i-Perphenazine ne-Amitriptyline Iphephile Ezinkingeni Zenhliziyo?

Lo muthi ungathinta ukushaya kwenhliziyo yakho nomfutho wegazi, ngakho-ke abantu abanezinkinga zenhliziyo badinga ukuhlolwa ngokucophelela ngaphambi kokuqala ukwelashwa. Udokotela wakho cishe uzo-oda i-EKG (ukuhlolwa kokushaya kwenhliziyo) futhi aqaphe ukusebenza kwenhliziyo yakho njalo uma unezinkinga zenhliziyo.

Uma unezinkinga zenhliziyo ezilula, udokotela wakho angase akwazi ukukuyalela lo muthi ngokuqapha okuseduze. Nokho, abantu abanezinkinga zenhliziyo ezinzima, ukuhlaselwa yinhliziyo kwamuva, noma iziyaluyalu ezithile zokushaya kwenhliziyo ngokuvamile badinga ezinye izindlela zokwelapha.

Njalo tshela udokotela wakho nganoma yiziphi izinkinga zenhliziyo, ngisho noma zibonakala zincane. Lolu lwazi lubasiza ukuthi benze izinqumo zokwelapha eziphephe kakhulu esimweni sakho esithile.

Ngingenzani Uma Ngisebenzisa Ngengozi i-Perphenazine ne-Amitriptyline eningi kakhulu?

Uma uthathe umthamo omkhulu kunalowo obekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma ungazizwa ugula okwamanje. Ukweqisa imithi kungabangela izimpawu ezinzima ezingase zingaveli ngokushesha.

Izimpawu zokweqisa imithi zingabandakanya ukozela okukhulu, ukudideka, ukushaya kwenhliziyo okungajwayelekile, ukuquleka, noma ubunzima bokuphefumula. Uma othile engazi lutho noma enobunzima bokuphefumula, shayela izinsiza eziphuthumayo ngokushesha.

Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo ngumhlinzeki wezempilo. Gcina ibhodlela lemithi nawe uma ufuna usizo lwezempilo ukuze abahlinzeki bezempilo bazi kahle ukuthi yini nokuthi kungakanani okuthathwe.

Kufanele Ngenzeni Uma Ngingaphuthelwa Umthamo We-Perphenazine kanye ne-Amitriptyline?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Esimweni esinjalo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi kakhulu. Uma uvame ukukhohlwa imithamo, cabanga ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi.

Uma uphuthelwa imithamo njalo, khuluma nodokotela wakho ngamasu okukusiza ukuthi ukhumbule. Ukulinganisa okuqhubekayo kubalulekile ukuthi le mithi isebenze ngempumelelo.

Ngingayeka Nini Ukuthatha I-Perphenazine kanye ne-Amitriptyline?

Yeka kuphela ukuthatha le mithi ngaphansi kokuqondisa kukadokotela wakho. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxiswa futhi kungase kubangele ukuthi izimpawu zakho zokuqala zibuye noma zibe zimbi kakhulu.

Udokotela wakho uzokwenza ishejuli yokunciphisa kancane kancane uma udinga ukuyeka imithi. Le nqubo ngokuvamile ithatha amasonto ambalwa kuya ezinyangeni, kuye ngokuthi usuyithathe isikhathi esingakanani futhi nokuthi umzimba wakho usabela kanjani.

Noma ngabe uzizwa ungcono ngokuphelele, ungayeki ukuthatha imithi ngokwakho. Abantu abaningi badinga ukuqhubeka nokwelashwa isikhathi eside ukuze bagcine ukuthuthuka kwabo.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Perphenazine ne-Amitriptyline?

Kufanele ukugweme utshwala ngokuphelele ngenkathi uthatha lo muthi. Utshwala bungakhuphula kakhulu imiphumela yokuthulisa futhi bungase bubangele ukwehla okuyingozi kwengcindezi yegazi noma izinkinga zokuphefumula.

Ngisho namanani amancane otshwala angabangela ukozela okwengeziwe, isiyezi, nokukhubazeka kokucabanga. Le nhlanganisela ingaba yingozi ikakhulukazi uma ushayela noma usebenzisa imishini.

Uma unezinkathazo mayelana nokusetshenziswa kotshwala noma ukuthola kunzima ukugwema ukuphuza, xoxa lokhu ngokusobala nodokotela wakho. Bangakunikeza izinsiza nokusekelwa ukukusiza ukuthi uphathe ukwelashwa kwakho ngemithi ngokuphepha.