Yini i-Phenelzine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Phenelzine iyikhambi elibhalwe ngudokotela elingelokwelapha ukucindezeleka elingelohlobo lwemithi ebizwa ngokuthi ama-monoamine oxidase inhibitors (MAOIs). Ngokuvamile ibhalwa lapho ezinye izidambisi zokucindezeleka zinganikezanga usizo olwanele ezimpawini zokucindezeleka. Nakuba ngokuvamile kungewona umuthi wokuqala odokotela abawusebenzisayo, i-phenelzine ingasebenza ngempumelelo kubantu abathile, ikakhulukazi labo abanokucindezeleka okungajwayelekile noma ukucindezeleka okungamelani nokwelashwa.

Yini i-Phenelzine?

I-Phenelzine iyisidambisi sokucindezeleka esinamandla esisebenza ngendlela ehlukile kunemithi eminingi yesimanje yokucindezeleka. Yilokho odokotela abakubiza ngokuthi i-monoamine oxidase inhibitor, okusho ukuthi ivimba ama-enzyme athile ebuchosheni bakho aqeda amakhemikhali alawula imizwa afana ne-serotonin, i-norepinephrine, ne-dopamine.

Lo muthi ukhona kusukela ngeminyaka yawo-1960 futhi usaqhubeka uyithuluzi elibalulekile ekwelapheni ukucindezeleka, ikakhulukazi lapho eminye imithi ingasebenzanga. Udokotela wakho angase acabangele i-phenelzine uma uzamile ezinye izidambisi zokucindezeleka eziningana ngaphandle kwempumelelo, noma uma unezimpawu ezithile ezisabela kahle kuma-MAOI.

I-Phenelzine idinga ukuqapha ngokucophelela kanye nemikhawulo yokudla, kodwa kubantu abaningi, inganikeza usizo olukhulu ezimpawini zokucindezeleka ezingathintwanga eminye imithi.

Yini i-Phenelzine Esetshenziselwa Yona?

I-Phenelzine isetshenziselwa ikakhulukazi ukwelapha i-major depressive disorder, ikakhulukazi lapho ezinye izidambisi zokucindezeleka zingasebenzanga. Ilusizo ikakhulukazi kubantu abanokucindezeleka okungajwayelekile, okuhlanganisa izimpawu ezinjengokwanda kwesifiso sokudla, ukulala ngokweqile, nokuzwela okukhulu ekuphikweni.

Odokotela bangase futhi babhale i-phenelzine ngezifo ezithile zokukhathazeka, okuhlanganisa i-social anxiety disorder ne-panic disorder. Abanye abantu abane-bulimia nervosa noma ezinye izifo zokudla nabo bangazuza kulo muthi.

Umhlinzeki wakho wezempilo angase ancome i-phenelzine uma uhlangabezana nezimpawu zokucindezeleka njengokudabuka okuqhubekayo, ukulahlekelwa intshisekelo emisebenzini, ukukhathala, noma ubunzima bokugxilisa ingqondo. Isebenza ikakhulu lapho lezi zimpawu zihlanganisa lokho odokotela abakubiza ngokuthi “izici ezingajwayelekile” njengokuphendula kwemizwa, lapho imizwa yakho ingathuthuka okwesikhashana ngokuqondene nezehlakalo ezinhle.

Isebenza Kanjani I-Phenelzine?

I-Phenelzine isebenza ngokuvimba ama-enzyme abizwa ngokuthi ama-monoamine oxidases ebuchosheni bakho. Lawa ma-enzyme ngokuvamile aqeda amakhemikhali abalulekile emizweni afana ne-serotonin, i-norepinephrine, kanye ne-dopamine. Lapho i-phenelzine ivimba lawa ma-enzyme, amakhemikhali amaningi azizwa kahle ahlala etholakala ebuchosheni bakho.

Cabanga ngayo njengokuvimba umsele kubhavu. Esikhundleni sokuthi amakhemikhali emizwa yobuchopho bakho ageleze ngokushesha, ahlala isikhathi eside ukuze asize ukuthuthukisa imizwa yakho futhi anciphise izimpawu zokucindezeleka. Le nqubo ithatha isikhathi, yingakho ungase ungazizwa izinzuzo ezigcwele amasonto amaningana.

Lo muthi ubhekwa njengonamandla futhi usebenza kahle, kodwa udinga ukuphathwa ngokucophelela kunezinto ezintsha zokucindezeleka. Izindaba ezinhle ukuthi kubantu abasabela kahle ku-phenelzine, inganikeza ukukhululeka okuhle ezimpawini zokucindezeleka ukuthi eminye imithi ayikwazanga ukusiza.

Kufanele Ngiyithathe Kanjani I-Phenelzine?

Thatha i-phenelzine ngendlela enembile njengoba udokotela wakho ekunqumele ngayo, ngokuvamile izikhathi ezi-2-3 ngosuku ngaphandle noma ngaphandle kokudla. Ungayithatha ngobisi noma ngamanzi, futhi akukhathazi ukuthi uyadla ngaphambi noma ngemva kokuyithatha. Nokho, ukuhlela izilinganiso zakho ngokuqhubekayo usuku lonke kusiza ukugcina amazinga aqinile ohlelweni lwakho.

Qala ngomthamo ophansi osebenzayo odokotela bakho abawuncomayo, ngokuvamile cishe i-15mg ethathwa izikhathi ezi-2-3 nsuku zonke. Udokotela wakho angase andise kancane umthamo wakho ngokusekelwe endleleni osabela ngayo futhi ubekezelele umuthi. Abantu abaningi bathatha phakathi kuka-45-90mg ngosuku, ehlukaniswe izilinganiso eziningi.

Into into okubaluleke kakhulu mayelana nokuthatha i-phenelzine ukulandela imikhawulo yokudla eqinile. Uzodinga ukugwema ukudla okunothile nge-tyramine, okuhlanganisa ushizi omdala, inyama elashwe, ukudla okubilisiwe, neziphuzo ezithile ezinotshwala. Udokotela wakho noma usokhemisi uzokunikeza uhlu oluningiliziwe lokudla okufanele ukugweme.

Ungayeki ukuthatha i-phenelzine ngokuzumayo, ngoba lokhu kungadala izimpawu zokuhoxisa ezingakhululeki. Uma udinga ukuyeka, udokotela wakho uzokusiza ukuthi unciphise kancane kancane emavikini amaningana.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Phenelzine?

Abantu abaningi badinga ukuthatha i-phenelzine okungenani izinyanga eziyi-6-12 ukuze bagcine ukuthuthuka kwabo ezimpawini zokucindezeleka. Udokotela wakho ngokuvamile uzoncoma ukuqhubeka nomuthi izinyanga eziningana ngemuva kokuqala ukuzizwa ungcono ukuvimbela ukucindezeleka ukuthi kubuye.

Abanye abantu bangase badinge ukuthatha i-phenelzine iminyaka, ikakhulukazi uma benokucindezeleka okuphindaphindayo noma uma eminye imithi yokucindezeleka ingasebenzi kahle kubo. Lokhu kuvamile ngokuphelele futhi kuphephile uma kuqashwe kahle ngumhlinzeki wakho wezempilo.

Isinqumo sokuthi uzoqhubeka isikhathi esingakanani i-phenelzine sincike ezintweni eziningana, okuhlanganisa ukuthi usabela kahle kangakanani emuthini, ukuthi ngabe uhlangabezana nemiphumela emibi, nomlando wakho wokucindezeleka. Udokotela wakho uzosebenza nawe ukunquma ubude bokwelashwa obungcono kakhulu esimweni sakho esithile.

Yiziphi Imiphumela Emibi ye-Phenelzine?

Njengayo yonke imithi, i-phenelzine ingadala imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi okulindelekile kungakusiza ukuthi uzizwe ulungiseleleke kakhulu futhi wazi ukuthi ungaxhumana nini nodokotela wakho.

Imiphumela emibi evamile abantu abaningi abayitholayo ihlanganisa:

• Ukuphatheka kabi ikhanda noma ukuzizwa unovalo, ikakhulukazi uma usukuma
• Ukozela noma ukukhathala emini
• Umlomo owomile
• Ukuqunjelwa
• Ukukhuluphala
• Imiphumela engemihle yezocansi efana nokwehla kwesifiso sobulili noma ubunzima bokufinyelela i-orgasm
• Izinkinga zokulala noma ukuqwasha
• Isicanucanu noma isisu esibuhlungu

Le miphumela engemihle evamile ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala. Abantu abaningi bathola ukuthi ukuhlala unamanzi kahle, ukudla ukudla okunothile nge-fiber, nokuzivocavoca njalo kungasiza ekuphatheni le miphumela.

Imiphumela engemihle engavamile kodwa engathi sína idinga ukunakekelwa kwezokwelapha ngokushesha. Lezi zimpawu ezingavamile kodwa ezibalulekile zihlanganisa:

• Ikhanda elibuhlungu elinamandla nokuqina kwentamo
• Ubuhlungu besifuba noma ukushaya kwenhliziyo okusheshayo
• Isicanucanu esibuhlungu nokuhlanza
• Ukukhuphuka kwegazi okungazelelwe, okukhulu
• Ukudideka noma ukucasuka
• Ukuphuzi kwesikhumba noma amehlo
• Umchamo omnyama noma izitulo eziphuthukile

Uma uhlangabezana nanoma iyiphi yale miphumela emibi, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezimo eziphuthumayo. Lezi zimpawu azivamile kodwa zingabonisa izinkinga ezingathi sína ezidinga ukwelashwa ngokushesha.

Ubani Ongafanele Athatha i-Phenelzine?

I-Phenelzine ayiphephile kuwo wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Izimo ezithile zezokwelapha nemithi kungase kusebenzisane ngendlela eyingozi ne-phenelzine.

Akufanele uthathe i-phenelzine uma une:

• Isifo sesibindi esibi noma izinkinga zesibindi
• Isifo sezinso esibi
• Isifo senhliziyo noma umfutho wegazi ophezulu ongagadiwe
• Umlando wokushaywa unhlangothi noma ukuphuma kwegazi ebuchosheni
• I-Pheochromocytoma (ithumba elingavamile le-adrenal gland)
• Njengamanje uthatha ezinye izidambisi zokucindezeleka, ikakhulukazi ama-SSRI noma ama-SNRI

Ngaphezu kwalokho, i-phenelzine idinga ukucatshangelwa ngokucophelela uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa. Udokotela wakho uzohlola izinzuzo nezingozi ngokucophelela kulezi zimo.

Ubudala bungaba yinto ebalulekile, njengoba abadala bengase bazwe kalula imiphumela emibi ye-phenelzine, ikakhulukazi isiyezi kanye nezinguquko zomfutho wegazi. Udokotela wakho angase aqale ngomthamo omncane futhi akuqaphele eduze uma uneminyaka engaphezu kwengama-65.

Amagama Omkhiqizo we-Phenelzine

Igama lomkhiqizo le-phenelzine yi-Nardil, okuyindlela evame kakhulu yokunikezwa yalo muthi. Ungase futhi ukubone kubhekiselwa kulo ngegama lawo elivamile, i-phenelzine sulfate, ebhodleleni lakho lemithi.

Noma ngabe uthola igama lomkhiqizo i-Nardil noma i-phenelzine ejwayelekile, kokubili kuqukethe isithako esifanayo esisebenzayo futhi kusebenza ngendlela efanayo. Ikhemisi lakho lingashintsha phakathi kwezinhlobo zomkhiqizo nezivamile kuye ngokutholakala kanye nomshwalense wakho.

Uma unezinkinga ngokushintsha phakathi kwezinhlobo zomkhiqizo nezivamile, khuluma nodokotela wakho noma usokhemisi. Bangasiza ekuqinisekiseni ukuthi uthola imithi eqhubekayo futhi baphendule noma yimiphi imibuzo mayelana nokusebenza noma imiphumela emibi.

Ezinye Izindlela ze-Phenelzine

Uma i-phenelzine ingakulungele, imithi eminingi ehlukile ingelapha ukucindezeleka ngempumelelo. Udokotela wakho angase acabangele ezinye izinhlobo ze-MAOIs njenge-tranylcypromine (Parnate) noma i-isocarboxazid (Marplan), esebenza ngendlela efanayo kodwa ingase ibe nemiphumela emibi ehlukile.

Ngokuvamile, odokotela bangase bazame ama-antidepressants amasha afana nama-selective serotonin reuptake inhibitors (SSRIs) njenge-sertraline (Zoloft) noma i-escitalopram (Lexapro). Le mithi ngokuvamile inezithiyo zokudla ezimbalwa kanye nokusebenzisana kwemithi kuno-phenelzine.

Ezinye izinketho zihlanganisa izithiyo ze-serotonin-norepinephrine reuptake (SNRIs) njenge-venlafaxine (Effexor) noma i-duloxetine (Cymbalta). Kwabanye abantu, ama-antidepressants angajwayelekile njenge-bupropion (Wellbutrin) noma i-mirtazapine (Remeron) angase abe ezinye izindlela ezinhle.

Enye indlela engcono kakhulu incike ezimpawini zakho ezithile, umlando wezokwelapha, nokuthi usabele kanjani eminye imithi. Udokotela wakho uzosebenza nawe ukuthola inketho efanelekayo yezidingo zakho.

Ingabe i-Phenelzine ingcono kunezinye izidambisi zokucindezeleka?

I-Phenelzine akudingeki ukuthi ingcono kunezinye izidambisi zokucindezeleka, kodwa ingasebenza kahle kakhulu kwabanye abantu nezinhlobo ezithile zokucindezeleka. Isebenza ikakhulukazi ekwelapheni ukucindezeleka okumelana nokwelashwa lapho eminye imithi ingasebenzanga.

Kubantu abanokucindezeleka okungajwayelekile, i-phenelzine ivame ukusebenza kangcono kunezidambisi zokucindezeleka ezintsha njenge-SSRIs. Ukucindezeleka okungajwayelekile kufaka phakathi izimpawu ezinjengokuphendula kwemizwa, ukwanda kwesifiso sokudla, ukulala kakhulu, nokuzwela okukhulu ekwenqatshweni.

Nokho, i-phenelzine idinga ukuphathwa ngokucophelela kunezidambisi zokucindezeleka zesimanje. Uzodinga ukulandela imikhawulo yokudla eqinile futhi uqaphele ukuxhumana okuningi okungenzeka kwemithi. Odokotela abaningi bakhetha ukuzama izidambisi zokucindezeleka ezintsha kuqala ngoba ngokuvamile kulula ukuziphatha futhi zinezithiyo ezimbalwa.

I-

I-Phenelzine ingathinta umfutho wegazi nezinga lokushaya kwenhliziyo, ngakho idinga ukucatshangelwa ngokucophelela uma unesifo senhliziyo. Udokotela wakho uzohlola isimo sakho senhliziyo esiqondile futhi angase anqume ukuthi izinzuzo zidlula izingozi, ikakhulukazi uma ezinye izidambisi zokucindezeleka zingasebenzi.

Uma unesifo senhliziyo esingesibi kakhulu, udokotela wakho angase akubhalele i-phenelzine ngokuqapha okuseduze. Cishe bazohlola umfutho wakho wegazi njalo futhi bangase baqale ngomthamo ophansi. Kodwa-ke, uma unesifo senhliziyo esibi kakhulu, umfutho wegazi ophezulu ongagadiwe, noma ukuhlaselwa yinhliziyo kwakamuva, i-phenelzine ingase ingakuphepheli.

Kufanele Ngenzeni Uma Ngisebenzisa I-Phenelzine Engakanani Ngengozi?

Uma ngengozi uthatha i-phenelzine eningi kakhulu, xhumana nodokotela wakho noma ukulawulwa kwemithi enobuthi ngokushesha, ngisho noma ungezwa izimpawu ngokushesha. Ukweqisa kungabangela izinguquko eziyingozi kumfutho wegazi, izinga lokushaya kwenhliziyo, kanye nezinga lokushisa lomzimba.

Izimpawu zokweqisa i-phenelzine zingabandakanya ikhanda elibuhlungu kakhulu, ubuhlungu besifuba, ukushaya kwenhliziyo okusheshayo, ukudideka, ukucasuka, noma ukulahlekelwa ukwazi. Ungalindi ukuthi izimpawu zivele ngaphambi kokufuna usizo, njengoba imiphumela yokweqisa ingalibala kodwa ibe yingozi.

Gcina inombolo yocingo yokulawulwa kwemithi enobuthi (1-800-222-1222 e-US) iseduze, futhi unganqikazi ukushayela izinsiza eziphuthumayo uma uhlangabezana nezimpawu ezinzima noma ungakwazi ukufinyelela udokotela wakho ngokushesha.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Phenelzine?

Uma uphuthelwa umthamo we-phenelzine, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe.

Ukuphuthelwa umthamo ngezikhathi ezithile akuyona ingozi, kodwa zama ukuthatha imithi yakho ngokuqhubekayo ukuze uthole imiphumela engcono kakhulu. Uma uvame ukukhohlwa imithamo, cabangela ukusebenzisa umhleli wamaphilisi noma ukusetha izikhumbuzi zocingo ukukusiza ukuthi uhlale emgwaqeni.

Uma uphuthelwa imithamo kaningi noma unokukhathazeka mayelana neshejuli yakho yemithi, khuluma nodokotela wakho noma usokhemisi. Bangakusiza ukuthi uthuthukise amasu okukhumbula imithi yakho noma ulungise ishejuli yakho yokulinganisa uma kudingeka.

Ngingayeka nini ukuthatha i-Phenelzine?

Ungayeki ukuthatha i-phenelzine ngokuzumayo, ngoba lokhu kungabangela izimpawu zokuhoxiswa ezingakhululekile njengokuquleka, isicanucanu, ikhanda elibuhlungu, kanye nezinguquko zemizwa. Udokotela wakho uzokusiza ukuthi unciphise kancane kancane umthamo wakho emasontweni amaningana uma sekuyisikhathi sokuyeka.

Isinqumo sokuyeka i-phenelzine kufanele senziwe ngaso sonke isikhathi nodokotela wakho, ngisho noma uzizwa ungcono kakhulu. Abantu abaningi badinga ukuqhubeka nokuthatha umuthi wabo wokucindezeleka izinyanga noma iminyaka ukuze bavimbele ukubuya kokucindezeleka.

Uma uhlangabezana nemiphumela emibi ekhathazayo noma ufuna ukuzama omunye umuthi, xoxa ngalokhu nodokotela wakho. Bangakusiza ukuthi udlulele ngokuphephile kokunye ukwelashwa ngenkathi kunciphisa ubungozi bezimpawu zokuhoxiswa noma ukubuya kokucindezeleka.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Phenelzine?

Kufanele ugweme utshwala ngenkathi uthatha i-phenelzine, ikakhulukazi izinhlobo ezithile zeziphuzo ezinotshwala. Ubhiya, iwayini, nezinye iziphuzo ezinotshwala ezigayiwe zingasebenzisana ngendlela eyingozi ne-phenelzine futhi kubangele ukwanda okungazelelwe, okukhulu kwengcindezi yegazi.

Ngisho namanani amancane otshwala angaba yinkinga, futhi ukusebenzisana kungenzeka ngemva kwamahora okuphuza. Abanye abantu bangase bakwazi ukuba namanani amancane kakhulu emimoya ethile efana ne-vodka noma i-gin, kodwa lokhu kufanele kwenziwe kuphela ngesiqondiso esiqondile sikadokotela wakho.

Indlela ephephe kakhulu ukugwema utshwala ngokuphelele ngenkathi uthatha i-phenelzine. Uma ukujabulela ukuphuza emphakathini, khuluma nodokotela wakho mayelana nemithi yokucindezeleka enye engase iphephe ukuyisebenzisa notshwala.