Yini i-Pimozide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Pimozide iyimithi kadokotela eyingxenye yeqembu lezidakamizwa ezibizwa ngokuthi ama-antipsychotics. Isetshenziswa ikakhulukazi ukwelapha i-Tourette's syndrome, isimo sezinzwa esibangela ama-tics angazithandeli kanye nokukhuluma. Cabanga nge-pimozide njengendlela yokuthulisa izimpawu zobuchopho eziqeda lezi zinyakazo nemisindo engathandeki.

Le mithi isebenza ngokuvimba amakhemikhali athile obuchopho abizwa ngokuthi ama-dopamine receptors. Ngenkathi iyithuluzi elinamandla lokuphatha izimpawu, idinga ukuqashwa ngokucophelela ngumhlinzeki wakho wezempilo ngenxa yemiphumela yayo engaba khona ekushayeni kwenhliziyo nakwezinye izinhlelo zomzimba.

Yini i-Pimozide Esetshenziselwa Yona?

I-Pimozide ivunyelwe ngokuqondile ukwelapha i-Tourette's syndrome lapho ezinye izindlela zokwelapha zingasebenzi ngempumelelo. Udokotela wakho ngokuvamile uzozama eminye imithi kuqala ngoba i-pimozide ithathwa njengenketho enamandla enemiphumela emibi engaba khona.

I-Tourette's syndrome ibangela kokubili ama-motor tics (ukuhamba okungazelelwe) nama-vocal tics (imisindo noma amagama). Lokhu kungahluka kusuka ekukhanyeni kwamehlo okulula noma ukukhwehlela kuya ekuziphatheni okuyinkimbinkimbi. I-Pimozide isiza ukunciphisa imvamisa nobukhulu balezi zimpawu ngokuthulisa amasekhethi obuchopho abangela zona.

Ngezinye izikhathi odokotela bangase babhale i-pimozide ezinye izimo, kodwa lokhu kwenziwa ngokucophelela kakhulu. Imithi ayivamisile ukusetshenziselwa ukukhathazeka okujwayelekile, ukucindezeleka, noma izinkinga zokuziphatha ezinganeni ngaphandle uma kunesizathu esithile sezokwelapha.

Isebenza Kanjani i-Pimozide?

I-Pimozide isebenza ngokuvimba ama-dopamine receptors ebuchosheni bakho. I-Dopamine iyisithunywa samakhemikhali esisiza ukulawula ukunyakaza nokuziphatha. Kubantu abane-Tourette's syndrome, izindlela ezithile ze-dopamine zisebenza ngokweqile, okuholela kuma-tics.

Lo muthi ubhekwa njenge-antipsychotic enamandla, okusho ukuthi unomthelela omkhulu kumakhemikhali obuchopho. Ihloselwe ngqo uhlelo lwe-dopamine ngokukhethekile kuneminye imithi, yingakho ingasebenza kahle kuma-tics. Kodwa-ke, lawa mandla asho nokuthi ingabangela imiphumela emibi ebalulekile.

Lo muthi awelaphi i-Tourette's syndrome, kodwa unganciphisa kakhulu izimpawu. Ungase uqaphele ukuthuthuka ekuvamekeni nasekubeni nzima kwama-tic emasontweni ambalwa ngemuva kokuqala ukwelashwa, nakuba kungathatha isikhathi eside ukuthola umthamo ofanele wena.

Kufanele Ngiyithathe Kanjani I-Pimozide?

Thatha i-pimozide ngendlela udokotela wakho ayala ngayo, ngokuvamile kanye ngosuku ngesikhathi sokulala. Ungayithatha ngokudla noma ngaphandle kokudla, kodwa ukuyithatha ngokudla kungasiza ukunciphisa ukuphazamiseka kwesisu uma uhlangabezana nanoma yikuphi.

Gwinya ithebhulethi yonke ngengilazi yamanzi egcwele. Ungayichobozi, uhlafune, noma uyiphule ithebhulethi, ngoba lokhu kungathinta indlela umuthi okhululwa ngayo emzimbeni wakho. Uma unenkinga yokugwinya amaphilisi, khuluma nomthengisi wakho wamaphilisi ngezinketho.

Kungcono ukuthatha i-pimozide ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo ohlelweni lwakho. Abantu abaningi bathola ukuthi isikhathi sokulala sisebenza kahle ngoba singabangela ukozela. Ukusetha isikhumbuzi sansuku zonke ocingweni lwakho kungakusiza ukuthi ukhumbule.

Gwema ama-grapefruit nejusi le-grapefruit ngenkathi uthatha i-pimozide, ngoba lokhu kungakhuphula ukugxila komuthi egazini lakho futhi kubangele imiphumela emibi eyingozi. Udokotela wakho uzophinda afune ukugwema eminye imithi ethile engasebenzisana ne-pimozide.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Pimozide?

Ubude bokwelashwa nge-pimozide buhluka kakhulu kumuntu nomuntu. Abanye abantu bangase bayidinge izinyanga, kanti abanye bangayithatha iminyaka. Udokotela wakho uzohlola njalo ukuthi usayidinga yini imithi nokuthi ngabe izinzuzo zisaqhubeka zidlula izingozi.

Umhlinzeki wakho wezempilo cishe uzofuna ukuzama ukunciphisa umthamo wakho ngezikhathi ezithile ukuze abone ukuthi izimpawu zakho zithuthuke ngokwanele yini ukusebenzisa imithi encane noma ukuyeka ngokuphelele. Lokhu kubaluleke kakhulu ezinganeni nakubantu abasha, njengoba izimpawu zabo zingashintsha njengoba bekhula.

Ungayeki ukuthatha i-pimozide ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa noma ukubuyela emuva kwama-tics okungenzeka abe mabi kakhulu kunakuqala. Uma udinga ukuyeka, udokotela wakho uzokwenza uhlelo lokunciphisa umthamo wakho kancane kancane.

Ukuqokwa okulandelayo njalo kubalulekile ngenkathi uthatha i-pimozide. Udokotela wakho uzoqapha isigqi senhliziyo yakho, ahlole imiphumela emibi, futhi ahlulele ukuthi imithi isebenza kahle kangakanani esimweni sakho esithile.

Yiziphi Imiphumela Emibi ye-Pimozide?

I-Pimozide ingabangela imiphumela eminingi emibi, kusukela kokulula kuya kokukhulu. Ezivamile kakhulu ongase uzithole zihlanganisa ukozela, isiyezi, nomlomo owomile. Lokhu kuvame ukuthuthuka njengoba umzimba wakho uzivumelanisa nemithi emasontweni ambalwa okuqala.

Nawa amanye imiphumela emibi ejwayelekile abantu abaningi abayitholayo lapho beqala i-pimozide:

• Ukozela noma ukukhathala
• Isiyezi, ikakhulukazi lapho usukuma
• Umlomo owomile
• Ukuqunjelwa
• Umbono ongacacile
• Ukukhuluphala
• Ukungazinzi noma ukuzwa ukuthuthumela

Le miphumela emibi ivamise ukulawuleka futhi ingancipha ngokuhamba kwesikhathi. Ukuphuza amanzi amaningi kungasiza ngomlomo owomile nokuqunjelwa, ngenkathi ukuvuka kancane ekuhlaliseni noma ekulaleni kunganciphisa isiyezi.

Noma kunjalo, kunemiphumela emibi ethile ekhulu edinga ukunakekelwa kwezempilo ngokushesha. Okukhathazayo kakhulu yinkinga yesigqi senhliziyo ebizwa ngokuthi i-QT prolongation, engaba yingozi empilweni. Udokotela wakho uzokwenza ukuqapha inhliziyo njalo ngenkathi uthatha i-pimozide.

Qaphela le miphumela emibi emibi futhi uthinte udokotela wakho ngokushesha uma uhlangabezana:

• Ukushaya kwenhliziyo okungajwayelekile noma ukushaya kwenhliziyo okusheshayo
• Ukuquleka noma ukusondela ekuqulekeni
• Isiyezi esinamandla
• Ukuqina kwemisipha noma ama-spasms
• Ukuthuthumela noma ukuzamazama
• Umkhuhlane omkhulu
• Ubunzima bokugwinya
• Ukunyakaza okungajwayelekile ongakwazi ukukulawula

Isimo esingavamile kodwa esibi esibizwa ngokuthi i-tardive dyskinesia singase sithuthuke ngokusebenzisa isikhathi eside. Lokhu kuhilela ukunyakaza okungazithandeli, ngokuvamile kobuso nolimi, okungase kuqhubeke ngisho nangemva kokuyeka umuthi. Udokotela wakho uzobheka izimpawu zakuqala zalesi simo.

Abanye abantu bangase futhi bahlangabezane ne-neuroleptic malignant syndrome, okuyisimo esingavamile kodwa esingabulala. Lokhu kuhlanganisa umkhuhlane omkhulu, ukuqina kwemisipha, ukudideka, kanye nezinguquko ekushayeni kwenhliziyo nengcindezi yegazi. Lokhu kudinga ukunakekelwa kwezimo eziphuthumayo.

Ubani Ongafanele Athatha I-Pimozide?

I-Pimozide ayiphephile kuwo wonke umuntu. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela lo muthi. Izimo eziningana nezimo zenza i-pimozide ingafaneleki noma ibe yingozi.

Akufanele uthathe i-pimozide uma unezimo ezithile zenhliziyo, ikakhulukazi lezo ezithinta ukushaya kwenhliziyo yakho. Lokhu kuhlanganisa i-long QT syndrome, umlando wokushaya kwenhliziyo okungajwayelekile, noma uma uthatha eminye imithi ethinta ukushaya kwenhliziyo.

Nazi izimo eziyinhloko ezivame ukuvimbela ukusetshenziswa kwe-pimozide:

• Ukuphazamiseka kokushaya kwenhliziyo (arrhythmias)
• I-Long QT syndrome
• Isifo senhliziyo esibi kakhulu
• Izinkinga zesibindi ezinzima
• Umlando womdlavuza wamabele
• Amathumba ancike ku-Prolactin
• Ukucindezeleka okukhulu kwesistimu yezinzwa emaphakathi

Udokotela wakho uzophinda aqaphele kakhulu ngokuyala i-pimozide uma usumdala, unezinkinga zezinso, noma uthatha imithi eminingi. Ubudala nezinye izimo zempilo zingakhuphula ingozi yakho yemiphumela emibi emibi.

Ukukhulelwa nokuncelisa kufuna ukucatshangelwa okukhethekile. I-Pimozide ingawela i-placenta futhi idlulele e-breast milk, okungase kuthinte ingane yakho. Udokotela wakho uzohlola izingozi nezinzuzo ngokucophelela uma ukhulelwe noma uhlela ukukhulelwa.

Eminye imithi ingase ihlangane ngendlela eyingozi ne-pimozide, ikakhulukazi lezo ezithinta ukushaya kwenhliziyo noma ukusebenza kwesibindi. Hlala utshela udokotela wakho ngayo yonke imithi, izithasiselo, nemikhiqizo yezitshalo oyithathayo.

Amagama Omkhiqizo we-Pimozide

I-Pimozide itholakala ngaphansi kwegama lomkhiqizo elithi Orap e-United States. Lolu uhlobo oluvame kakhulu olubhalwe ngudokotela lomuthi futhi luza ngesimo samaphilisi.

Emazweni angaphandle, i-pimozide ingathengiswa ngaphansi kwamanye amagama omkhiqizo. Kodwa-ke, kungakhathaliseki igama lomkhiqizo, isithako esisebenzayo nemiphumela kuhlala kufana. Umuthi wakho ungakusiza ukuthi ubone ukuthi uthola umuthi olungile.

Izinhlobo ze-generic ze-pimozide nazo ziyatholakala, eziqukethe isithako esisebenzayo esifanayo kodwa zingase zibukeke zihlukile kunohlobo lwegama lomkhiqizo. Imithi ye-Generic isebenza kahle njengaleyo yegama lomkhiqizo futhi ivame ukubiza kancane.

Ezinye izindlela ze-Pimozide

Eminye imithi eminingi ingelapha i-Tourette's syndrome, futhi udokotela wakho uzovame ukuzama lezi ngaphambi kokucabangela i-pimozide. Ukukhetha kuncike ezimpawini zakho ezithile, umlando wezokwelapha, nokuthi uyikwazi kanjani ukubekezelela imithi ehlukene.

Ukwelashwa kokuqala kwe-Tourette's syndrome kuvame ukuhlanganisa imithi ethathwa njengephephile kune-pimozide. Lokhu kuhlanganisa i-clonidine, i-guanfacine, ne-topiramate. Le mithi inemiphumela emibi embalwa futhi ayidingi izinga elifanayo lokuqapha inhliziyo.

Eminye imithi ye-antipsychotic efana ne-risperidone, i-aripiprazole, noma i-haloperidol nayo ingase icatshangelwe. Ngamunye unohlu lwakhe lwemiphumela emibi nokusebenza kwabantu abahlukene. Udokotela wakho uzosiza ekunqumeni ukuthi iyiphi inketho engasebenza kangcono esimweni sakho.

Izindlela ezingasebenzisi imithi nazo zingaba usizo olukhulu ekuphatheni i-Tourette's syndrome. Lokhu kufaka phakathi ukwelashwa ngokuziphatha, ikakhulukazi inqubo ebizwa ngokuthi i-Comprehensive Behavioral Intervention for Tics (CBIT). Lokhu kwelashwa kusiza abantu ukuthi bafunde ukuphatha ama-tics abo ngokuqwashisa nokuphendula okuncintisanayo.

Isinqumo sokusebenzisa i-pimozide ngokuvamile siza ngemva kokuzama ezinye izinketho kuqala, ngenxa yamandla ayo okuba nemiphumela emibi. Udokotela wakho uzocabangela izimpawu zakho ezithile, ukuthi ziphazamisa kangakanani impilo yakho yansuku zonke, kanye nesimo sakho sempilo esiphelele.

Ingabe i-Pimozide Ingcono Kune-Haloperidol?

Kokubili i-pimozide ne-haloperidol yimithi elwa nokugula kwengqondo esetshenziselwa ukwelapha i-Tourette's syndrome, kodwa inamandla nobuthakathaka obuhlukene. Akukho noyedwa ongcono ngokujwayelekile - ukukhetha kuncike ezidingweni zakho ngazinye nokuthi umzimba wakho usabela kanjani emithini ngayinye.

I-Pimozide ivame ukucatshangelwa njengeqondene kakhulu esenzweni sayo, okusho ukuthi ingase ibangele imiphumela emibi ehlobene nokunyakaza okuncane kune-haloperidol. Kodwa-ke, i-pimozide inengozi enkulu yezinkinga zesigqi senhliziyo, okudinga ukuqapha njalo nge-electrocardiograms (EKGs).

I-Haloperidol isetshenziswe isikhathi eside futhi ngokuvamile ayibizi kakhulu kune-pimozide. Ingasebenza kahle kakhulu kuma-tics, kodwa ingase ibangele imiphumela emibi ehlobene nokunyakaza okwengeziwe njengokuqina, ukuthuthumela, noma ukungazinzi. Le miphumela emibi ivame ukuhlobana nomthamo futhi ingathuthuka ngokulungiswa.

Udokotela wakho uzocabangela izici eziningana lapho ekhetha phakathi kwale mithi. Lokhu kufaka phakathi iminyaka yakho, ezinye izimo zempilo, eminye imithi oyithathayo, kanye nezimpendulo zakho zangaphambilini emithini efanayo. Abanye abantu benza ngcono ngomuthi owodwa kanti abanye basabela kangcono kwenye indlela.

Imibuzo Evame Ukubuzwa Nge-Pimozide

Ingabe i-Pimozide Iphephile Esimeni Senhliziyo?

I-Pimozide ngokuvamile ayinconyelwe abantu abanezifo zenhliziyo ezikhona, ikakhulukazi labo abanezinkinga zokushaya kwenhliziyo. Lo muthi ungabangela isimo esibizwa ngokuthi i-QT prolongation, esithinta uhlelo lukagesi lwenhliziyo futhi lungaholela ekuphazamisekeni okuyingozi kokushaya kwenhliziyo.

Uma unesifo senhliziyo, udokotela wakho cishe uzoqala ngokuhlola ezinye izindlela zokwelapha. Kodwa-ke, ezimweni ezingavamile lapho i-pimozide idingeka ngempela, uzodinga ukuqashwa okuseduze kakhulu kwenhliziyo. Lokhu kufaka phakathi ama-EKG avamile futhi mhlawumbe ukubonisana nochwepheshe wenhliziyo.

Ngisho nabantu abangenazo izinkinga zenhliziyo ezaziwayo badinga ukuqashwa kwenhliziyo njalo ngenkathi bethatha i-pimozide. Udokotela wakho uzoqala izivivinyo ngaphambi kokuqala umuthi futhi aqhubeke nokuqapha ngesikhathi sokwelashwa ukuze abambe noma yiziphi izinkinga ekuqaleni.

Kufanele Ngenzeni Uma Ngisebenzisa I-Pimozide Eningi Ngengozi?

Uma ngengozi uthatha i-pimozide eningi, xhumana nokulawulwa kwezinto ezinobuthi noma uye egumbini eliphuthumayo ngokushesha. Ukweqisa kungabangela izinkinga ezinkulu zokushaya kwenhliziyo, ukozela okukhulu, noma ukulahlekelwa ukwazi.

Ungalindi ukubona ukuthi uzizwa ulungile yini – ukweqisa i-pimozide kungaba yingozi empilweni. Letha ibhodlela lomuthi nawe ukuze usize abahlinzeki bezempilo baqonde kahle ukuthi uthathe ini nokuthi uthathe malini. Uma omunye umuntu ethatha umuthi ngengozi, thola usizo oluphuthumayo ngokushesha.

Izimpawu zokweqisa i-pimozide zifaka phakathi ukozela okukhulu, ukuquleka, ukushaya kwenhliziyo okungajwayelekile, ukuqina kwemisipha, nobunzima bokuphefumula. Lezi zimpawu zidinga ukunakekelwa kwezokwelapha ngokushesha, njengoba zingaba zimbi ngokushesha ngaphandle kokwelashwa.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Pimozide?

Uma uphuthelwa umthamo we-pimozide, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo. Uma sekuseduze nomthamo wakho olandelayo ohleliwe, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo owuphuthelwe. Lokhu kungakhuphula ingozi yakho yemiphumela emibi, ikakhulukazi izinkinga zesigqi senhliziyo. Ukuthatha imithamo emibili ye-pimozide kungaba yingozi futhi kufanele kugwenywe ngaso sonke isikhathi.

Uma uvame ukukhohlwa imithamo, cabangela ukusetha i-alamu yansuku zonke noma ukusebenzisa umhleli wamaphilisi. Ukuthatha imithamo ngokuqhubekayo kusiza ukugcina amazinga aqhubekayo omuthi emzimbeni wakho, okubalulekile kokubili ekusebenzeni nasekuvikelekeni.

Ngingayeka nini ukuthatha i-Pimozide?

Kufanele uyeke kuphela ukuthatha i-pimozide ngaphansi kokuqondisa kukadokotela wakho. Isinqumo sokuyeka sincike ekutheni izimpawu zakho zilawulwa kahle kangakanani, ukuthi usuthatha isikhathi esingakanani umuthi, nokuthi ngabe uhlangabezana nemiphumela emibi enezinkinga.

Udkt wakho cishe uzofuna ukunciphisa umthamo wakho kancane kancane kunokuyeka kungazelelwe. Lokhu kusiza ukuvimbela izimpawu zokuhoxiswa futhi kuvumela ukuqapha ukuthi ama-tics akho asabela kanjani ekunciphisweni komthamo. Abanye abantu bathola ukuthi izimpawu zabo zithuthuke ngokwanele ukusebenzisa umthamo ophansi noma bayeke ngokuphelele.

Isikhathi sokuyeka siyahlukahluka kakhulu phakathi kwabantu ngabanye. Abanye abantu bangazama ukunciphisa noma bayeke ngemuva kwezinyanga zokulawulwa okuhle kwezimpawu, kanti abanye bangadinga ukwelashwa kwesikhathi eside. Ukuqokwa okuvamile kokulandela ngemuva kusiza ukunquma isikhathi esifanele sakho.

Ngingashayela ngenkathi ngithatha i-Pimozide?

I-Pimozide ingabangela ukozela, isiyezi, nombono ongacacile, okungathinta ikhono lakho lokushayela ngokuphepha. Uma uqala ukuthatha umuthi noma lapho umthamo wakho ushintsha, kungcono ukugwema ukushayela uze wazi ukuthi kukuthinta kanjani.

Abantu abaningi bathola ukuthi le miphumela emibi iyathuthuka ngemuva kwamasonto ambalwa njengoba umzimba wabo ujwayela umuthi. Kodwa-ke, uma uqhubeka nokuzwa ukozela okukhulu noma isiyezi, akufanele ushayele noma usebenzise imishini.

Xoxa nodokotela wakho ngesimo sakho esiqondile. Bangakusiza ukuthi uqonde ukuthi kungaba nini kuphephile ukuqhubeka nokushayela nokuthi yiziphi izimpawu okufanele uziqaphele ezibonisa ukuthi akufanele ube ngemuva kwesondo. Ukuphepha kwakho nokuphepha kwabanye emgwaqeni kufanele ngaso sonke isikhathi kube yinto eza kuqala.