Quizartinib (indlela yokwelapha ngomlomo)
Imikhiqizo etholakalayo
Vanflyta
Mayelana naleli khambi
I-Quizartinib isetshenziswa ndawonye nezinye izidakamizwa (um., i-cytarabine, i-anthracycline) futhi iyodwa njengonyango lokuqhubeka ukuze ikwelase i-acute myeloid leukemia kubantu abanesifo se-FLT3-ITD mutation. Udokotela wakho uzohlola ukuba kukhona yini le mutation. Lena imithi itholakala kuphela ngaphansi kohlelo lokusabalalisa oluqediwe okuthiwa yi-Vanflyta® REMS (Risk Evaluation and Mitigation Strategy) Program. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucineni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqulu ozothatha wena nodokotela wakho. Kulo muthi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqondile noma oluhambisana nokwaleka kulo muthi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unanoma yiluphi olunye uhlobo lwezifo ezingalawuleki, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenaso iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela ka-quizartinib kubantwana. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-quizartinib kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayinconywa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangcono nini imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma ngesikhathi sokudla izinhlobo ezithile zokudla ngoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba ngezidakamizwa ezithile kungabangela ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi esetshenziswa ekwelapheni umdlavuza inamandla kakhulu futhi ingaba nemiphumela eminingi emibi. Ngaphambi kokusebenzisa le mithi, qiniseka ukuthi uyayiqonda yonke imingcele nezinzuzo. Kubalulekile ukuthi usebenzisane eduze nodokotela wakho phakathi nokwelashwa kwakho. Thatha le mithi kuphela njengoba uqondiswe udokotela wakho. Ungayithathi ngaphezulu, ungayithathi kaningi, futhi ungayithathi isikhathi eside kunalokho oqondiswe udokotela wakho. Kubaluleke kakhulu ukuthi uyiqonde imfuneko yohlelo lwe-Vanflyta® REMS kanye ne-Medication Guide. Funda futhi ulandele lezi zinkomba ngokucophelela. Buza udokotela wakho uma unemibuzo. Cela umthengisi wemithi i-medication guide uma ungenayo. Ungayithatha le mithi ngokudla noma ngaphandle kokudla. Thatha le mithi ngesikhathi esifanayo nsuku zonke. Gwinya ithebulethi yonke. Ungayisiqi, ungayicwili, noma ungayikunyathele. Inani lemithi elizothathwa lizohlukahluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemibhalweni. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi ale mithi. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lemithi osilithatha lixhomeke emandleni emithi. Futhi, inani lemithi oyiphuzayo nsuku zonke, isikhathi esivunyelwe phakathi kwamadosi, nobude besikhathi othatha imithi kuya ngenkinga yezokwelapha oyisebenzisela imithi. Uma uphuthelwa yidosi yale mithi, yithatha ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi sedosi yakho elandelayo, susa idosi oyiphuthelwe futhi ubuyele esimweni sakho sokuthatha imithi. Ungawandisi ama-dosi. Uma uhlanza ngemuva kokuthatha idosi yale mithi, ungayithathi idosi eyengeziwe. Thatha idosi elandelayo ngesikhathi esivamile. Gcina imithi esitsheni esivalekile ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungayivumeli ukuba iqhube. Gcina ingafinyeleleki kubantwana. Ungagcini imithi esephelile noma imithi engasasetshenziswa. Buza ochwepheshe bakho bezempilo ukuthi kufanele uyilahla kanjani noma iyiphi imithi ongayisebenzisi.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.