Yini i-Racepinephrine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Racepinephrine iyimithi ye-bronchodilator esiza ukuvula imigudu yakho yomoya uma unenkinga yokuphefumula. Ivame ukusetshenziswa njengomuthi wokwelapha ongatholakali ngaphandle kwemvume kadokotela wokuphefumula okuncane njenge-croup, i-bronchitis, nezimpawu ze-asthma.

Lo muthi usebenza ngokukhulula imisipha ezungeze imigudu yakho yomoya, okwenza kube lula ukuthi umoya ungene futhi uphume emaphashini akho. Ungase uyibone ngamagama omkhiqizo afana ne-Asthmanefrin noma i-S2, futhi ngokuvamile yilona ukwelashwa kokuqala abazali abakuthathayo lapho ingane yabo ithuthukisa lokho kukhohlokho okukhethekile kwe-croup.

Yini i-Racepinephrine?

I-Racepinephrine iyinguqulo yokwenziwa ye-epinephrine eyenzelwe ngqo ukuhogelwa. Ingowodwa ohlwini lwemithi olubizwa ngokuthi i-sympathomimetics, elingisa imiphumela yamahomoni akho okucindezeleka emzimbeni.

Ngokungafani nama-auto-injectors e-epinephrine anqunywe ngudokotela asetshenziselwa ukusabela okukhulu komzimba, i-racepinephrine ithambile futhi iyatholakala ngaphandle kwemvume kadokotela. Yenziwe njengesixazululo esiwuketshezi osiphefumulayo nge-nebulizer noma i-inhaler ephathwayo, okuvumela umuthi ukuthi usebenze ngqo ohlelweni lwakho lokuphefumula.

Igama elithi "race" ku-racepinephrine libhekisela esakhiweni sayo samakhemikhali, esiqukethe zombili izinguqulo ezingakwesobunxele nakwesokudla ze-molecule ye-epinephrine. Le nhlanganisela elinganiselayo inikeza i-bronchodilation esebenzayo ngenkathi kungenzeka ukuthi inciphisa eminye imiphumela engemihle uma iqhathaniswa ne-epinephrine emsulwa.

Isetshenziselwani i-Racepinephrine?

I-Racepinephrine isetshenziswa ikakhulukazi ukwelapha ubunzima bokuphefumula obuncane kuya kobujwayelekile obubangelwa ukuvuvukala noma ukuqina kwemigudu yomoya. Isebenza ikakhulukazi ezimweni ezibangela ukuthi imigudu yomoya engenhla inciphe.

Ukusetshenziswa okuvamile kakhulu kungokwe-croup ezinganeni, lokho kutheleleka ngegciwane elibangela ukukhwehlela okufana nophawu kanye nobunzima bokuphefumula. Abazali abaningi bakuthola kunikeza ukukhululeka okusheshayo lapho ingane yabo ivuka phakathi kwamabili ilwa nokuphefumula.

Nawa amakhambi amakhulu lapho i-racepinephrine ingasiza ukunikeza ukukhululeka:

• I-Croup (laryngotracheobronchitis) ezinganeni nakubantu abadala
• Izimpawu ze-asthma ezithambile kanye ne-bronchospasm
• I-bronchitis ebukhali enokuhlaselwa
• Ukungezwani komzimba okuthambile okuthinta imigudu yomoya
• I-Stridor ngemuva kokukhipha i-extubation (ukuqubuka komoya ngemuva kokususwa kweshubhu lokuphefumula)

Ngenkathi isebenza ngempumelelo kulezi zimo, i-racepinephrine ayifaneleki ekuhlaselweni kwe-asthma okukhulu noma ezimweni eziphuthumayo zokuphefumula ezisongela impilo. Lezo zimo zidinga ukunakekelwa kwezokwelapha ngokushesha kanye nemithi eqinile kadokotela.

Isebenza Kanjani I-Racepinephrine?

I-Racepinephrine isebenza ngokuvuselela ama-receptors athile emisipha yakho yomoya abizwa ngokuthi ama-beta-2 adrenergic receptors. Lapho la ma-receptors esebenza, abangela ukuthi imisipha ebushelelezi ezungeze imigudu yakho yomoya iphumule futhi yande.

Cabanga ngemigudu yakho yomoya njengamashubhu engadi angacindezela aqine noma aphumule avuleke. Uma unenkinga yokuphefumula, ukuvuvukala noma imisipha yemisipha yenza la ma-“hose” anciphise, okwenza kube nzima ukuthi umoya udlule. I-Racepinephrine isebenza njengesiginali etshela le misipha ukuthi ithukulule futhi ivuleke kakhulu.

Umuthi futhi unomphumela othambile wokulwa nokuvuvukala, okungasiza ukunciphisa ukuvuvukala ezicutshini zomoya. Lesi senzo esiphindwe kabili sokuphumula kwemisipha nokunciphisa ukuvuvukala yingakho sisebenza ikakhulukazi ezimweni ezinjenge-croup, lapho zombili lezi zinto zifaka isandla ebunzimeni bokuphefumula.

Njengoba kuyi-bronchodilator, i-racepinephrine ithathwa njengeqinile ngokulinganiselwe. Inamandla kakhulu kunezinye izinketho ezingathengiswa ngaphandle kwemvume kodwa ithambile kunezithako ezibhalwe ngudokotela njenge-albuterol. Lokhu kuyenza ibe yinketho emaphakathi enhle yokuphatha izimpawu ezilula kuya kweziphakathi ekhaya.

Kufanele Ngiyithathe Kanjani I-Racepinephrine?

I-Racepinephrine ithathwa ngokuphefumula kusetshenziswa umshini we-nebulizer noma idivayisi ye-inhaler ephathwayo. Umuthi uza njengesixazululo esiwuketshezi esiguqulwa sibe inkungu enhle ukuze uyiphefumule ngokujulile.

Ukuze isetshenziswe nge-nebulizer, ngokuvamile uzonciphisa isixazululo se-racepinephrine ngosawoti ohlanzekile njengoba kuqondiswe ephaketheni. Umthamo ojwayelekile wabantu abadala uvame ukuba ngu-0.5 mL we-racepinephrine oxutshwe no-2.5 mL kasawoti, ophefumulwa ngemizuzu engu-10-15.

Nansi indlela yokusebenzisa i-racepinephrine ngokuphepha nangempumelelo:

1. Geza izandla zakho kahle ngaphambi kokubamba umuthi
2. Linganisela umthamo ofanele usebenzisa idivayisi yokulinganisa enikeziwe
3. Faka umuthi enkomishini yakho ye-nebulizer noma i-inhaler njengoba kuqondiswe
4. Hlala uqonde futhi uphefumule ngokujwayelekile ngomlomo
5. Qhubeka kuze kube yilapho wonke umuthi usuphelile (ngokuvamile imizuzu engu-10-15)
6. Geza umlomo wakho ngamanzi ngemva kokwelashwa

Akudingeki ukuthi uthathe lo muthi nokudla, kodwa ukuba nesnakhi esilula ngaphambi kwesikhathi kungasiza ekuvikeleni isisu uma uzwela emithini. Gwema ukudla ukudla okukhulu ngaphambi kokwelashwa, njengoba lokhu kungase kukwenze uzizwe unesiyezi ngesikhathi sokuphefumula.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Racepinephrine?

I-Racepinephrine yenzelwe ukusetshenziswa kwesikhashana ngesikhathi seziqephu zokuphefumula eziqatha, hhayi njengomuthi wansuku zonke wesikhathi eside. Abantu abaningi bayayisebenzisa izinsuku ezimbalwa nje kuze kube yilapho izimpawu zabo zithuthuka.

Nge-croup, ungase uyisebenzise izikhathi ezi-2-3 phakathi nesikhathi esingamahora angu-24-48 njengoba izimpawu zivela. Ngezimpawu ze-bronchitis noma i-asthma elula, ukwelashwa kuvame ukuhlala izinsuku ezi-3-5 ubuningi. Imiphumela yomthamo ngamunye ivame ukuhlala amahora angu-1-3.

Uma uzithola udinga i-racepinephrine isikhathi esingaphezu kwesonto elilodwa, noma uma uyisebenzisa izikhathi ezingaphezu kwezi-3-4 ngosuku, sekuyisikhathi sokuxhumana nomhlinzeki wezempilo. Ukusetshenziswa isikhathi eside ngaphandle kokugadwa kwezokwelapha akukhuthazwa futhi kungase kubonise ukuthi udinga indlela ehlukile yokwelashwa.

Njalo landela imiyalelo ethile ekupakisheni komkhiqizo wakho, njengoba amabhrendi ahlukene angase abe nezincomo zokulinganisa ezihlukile. Uma ungabaza, okuncane kuvame ukuba ngaphezulu ngemithi ye-bronchodilator.

Yiziphi Imiphumela Eceleni ye-Racepinephrine?

Abantu abaningi bayayibekezelela i-racepinephrine kahle, ikakhulukazi uma isetshenziswa njengoba kuqondiswe isikhathi esifushane. Imiphumela emibi ngokuvamile imnene futhi yesikhashana, ngokuvamile ihlala kuphela uma imithi isebenza ohlelweni lwakho.

Imiphumela emibi evame kakhulu ongase uyithole ihlobene nemiphumela efana ne-stimulant yomuthi ohlelweni lwakho lwezinzwa. Lokhu kwenzeka ngoba i-racepinephrine ithinta izamukeli emzimbeni wakho wonke, hhayi emaphashini akho kuphela.

Nansi imiphumela emibi ongase uyibone, iqala ngaleyo evame kakhulu:

• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile (ukushaya kwenhliziyo)
• Ukuthuthumela okuncane noma ukuzamazama ezandleni zakho
• Ukuzizwa unovalo, ukhathazekile, noma uqhaqhazela
• Ukwanda okuncane kwengcindezi yegazi
• Ikhanda noma isiyezi esincane
• Isicanucanu noma isisu esibuhlungu
• Ubunzima bokulala uma isetshenziswa ngasikhathi sokulala

Le miphumela evamile ivame ukunyamalala phakathi kwemizuzu engama-30-60 ngemuva kokuthi ukwelashwa kwakho kuphele. Ziphendula umzimba wakho ngendlela ejwayelekile emuthini futhi ngokuvamile akuyona imbangela yokukhathazeka ngaphandle kokuthi zinzima noma ziqhubeka.

Nakuba kungavamile, abanye abantu bangase babe nemiphumela emibi engathi sína edinga ukunakekelwa kwezokwelapha ngokushesha. Lokhu kuhlanganisa ubuhlungu obukhulu besifuba, ukushaya kwenhliziyo okusheshayo kakhulu (ngaphezu kokushaya okungu-120 ngomzuzu ngesikhathi sokuphumula), isiyezi esikhulu noma ukuquleka, noma izimpawu zokuphendula komzimba ngendlela engavamile njengokuqubuka, ukuvuvukala, noma ubunzima bokugwinya.

Uma unezinkinga zenhliziyo, umfutho wegazi ophezulu, noma isifo sikashukela, ungase uzwe kalula le miphumela. Hlala uxoxa ngomlando wakho wezokwelapha nomkhemisi noma udokotela ngaphambi kokuqala noma yimuphi umuthi omusha, ngisho nalowo ongawuthola ngaphandle kwemvume kadokotela.

Obani okungafanele basebenzise i-Racepinephrine?

Ngenkathi i-racepinephrine itholakala ngaphandle kwemvume kadokotela, ayifanele wonke umuntu. Izimo ezithile zezokwelapha nemithi kungayenza ingaphephile noma ingasebenzi kahle.

Kufanele ukugweme ukusebenzisa i-racepinephrine uma unezimo ezithile zenhliziyo, ikakhulukazi ukushaya kwenhliziyo okungajwayelekile, isifo esibi semithambo yenhliziyo, noma uma usanda kuba nesifo senhliziyo. Umuthi ungabeka ingcindezi eyengeziwe ohlelweni lwakho lwe-cardiovascular.

Nazi izimo eziyinhloko lapho i-racepinephrine kufanele igwenywe khona noma isetshenziswe ngokucophelela okukhulu:

• Ukungezwani okwaziwayo ne-epinephrine noma imithi efanayo
• Isifo senhliziyo esibi noma ukuhlaselwa yinhliziyo kwakamuva
• Umfutho wegazi ophezulu ongagadiwe
• I-Hyperthyroidism (ithoyidi elisebenza ngokweqile)
• I-Narrow-angle glaucoma
• Isifo sikashukela esibi esinokuguquguquka kweshukela eliningi
• Ukuphuza imithi ethile yokucindezeleka (MAOIs noma tricyclics)

Abesifazane abakhulelwe nabancelisa ibele kufanele baxoxe nomhlinzeki wabo wezempilo ngaphambi kokusebenzisa i-racepinephrine, nakuba ngokuvamile ithathwa njengephephile kunezinye izindlela ngesikhathi sokukhulelwa. Umuthi ungangena obisini lwebele ngamanani amancane.

Ezinganeni ezingaphansi kweminyaka engu-4 ubudala, ukuqashwa kwezokwelapha kunconywa ngokuqinile. Ngenkathi i-racepinephrine ingasebenza kahle ku-croup yezingane, izingane ezincane zingase zizwe kalula imiphumela emibi futhi zidinga ukuqashwa ngokucophelela.

Amagama Omkhiqizo we-Racepinephrine

I-Racepinephrine itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Asthmanefrin iyona eyaziwa kakhulu. Uzoyithola esigabeni sokuphefumula samakhemisi amaningi, ngokuvamile eduze kweminye imithi yokukhwehlela nokubanda.

I-Asthmanefrin yigama lokuqala nelivame kakhulu, elitholakala njengesisombululo se-nebulizer kanye nakwamanye amafomethi e-inhaler aphathwayo. Sekuneminyaka eminingi emakethe futhi inerekhodi eliqinile lokwelapha izimpawu zokuphefumula ezithambile.

I-S2 elinye igama lomkhiqizo ongahlangana nalo, nakuba lingavamile njenge-Asthmanefrin. Ezinye izinhlobo ezivamile nazo ziyatholakala, ngokuvamile zibhalwe ngokuthi "isisombululo sokuphefumula se-racepinephrine."

Yonke le mikhiqizo iqukethe isithako esifanayo esisebenzayo futhi isebenza ngendlela efanayo. Umehluko omkhulu usekupakisheni, ukugxila, kanye nentengo. Izinhlobo ezivamile zivame ukuba ngentengo ephansi ngenkathi zinikeza ukusebenza okulinganayo.

Ezinye izindlela ze-Racepinephrine

Uma i-racepinephrine ingatholakali noma ingakulungele, ezinye izindlela ezingasiza ngezinkinga zokuphefumula ezifanayo. Ukukhetha okungcono kuncike esimweni sakho esithile nobukhulu bezimpawu.

Nge-croup ethambile kanye ne-bronchitis, ama-humidifier omoya opholile kanye nokwelashwa ngomusi kungahlinzeka ngokuphumula kwemvelo. Abazali abaningi bathola ukuthi ukuhlala endlini yokugezela enomusi noma ukukhipha ingane yabo ngaphandle emoyeni opholile wasebusuku kusiza cishe njengemithi.

Nazi ezinye izindlela okufanele zicatshangelwe, kusukela ezithambile kuye kwezinamandla:

• Umoya o-humidified kanye nokwelashwa ngomusi (okwemvelo, akukho miphumela emibi)
• Ukwelashwa nge-saline nebulizer (ethambile, kusiza ukususa amafinyila)
• I-Albuterol inhaler (incwadi kadokotela, i-bronchodilator enamandla)
• I-Levalbuterol (incwadi kadokotela, inguqulo ethuthukisiwe ye-albuterol)
• Ama-corticosteroids omlomo afana ne-prednisolone (incwadi kadokotela, ezimweni ezinzima)

Ukuze kulawulwe umfutho wokuphefumula oqhubekayo, udokotela wakho angase ancome imithi yokulawula yansuku zonke efana nama-corticosteroids aphefumulwayo esikhundleni sokuncika kuma-bronchodilators okusindisa. Lokhu kusebenza ngendlela ehlukile ngokuvimbela ukuvuvukala kunokumane kuphathe izimpawu ngemva kokuthi zenzeke.

Izindlela zemvelo ezinjengokuzivocavoca ukuphefumula, ukugwema izinto ezibangela ukugula, nokugcina impilo enhle iyonke nazo zinganciphisa isidingo sakho sanoma imaphi amakhambi e-bronchodilator ngokuhamba kwesikhathi.

Ingabe i-Racepinephrine ingcono kune-Albuterol?

I-Racepinephrine ne-albuterol zombili ziyizidakamizwa eziphumelelayo ze-bronchodilator, kodwa zakhelwe izimo ezihlukene. Akukho noyedwa ongcono kunomunye - kuncike ezidingweni zakho ezithile nesimo sezokwelapha.

I-Racepinephrine ithambile futhi iyatholakala ngaphandle kwemvume kadokotela, okwenza kube lula ukwelapha izimpawu ezithambile ekhaya. Ilungele ikakhulukazi i-croup ngoba isebenza kahle ekukhukhumeni komoya ongaphezulu. Imiphumela ithambile kodwa futhi ihlala isikhathi esifushane kune-albuterol.

I-Albuterol inamandla futhi ihlala isikhathi eside, okwenza ibe ngcono ezimpawini ze-asthma eziphakathi nendawo kuya kwezinkulu. Kuyimithi kadokotela enikeza i-bronchodilation enamandla futhi ngokuvamile ihlala amahora angu-4-6 uma iqhathaniswa nama-racepinephrine amahora angu-1-3.

Ezimweni eziphuthumayo noma ubunzima bokuphefumula obukhulu, i-albuterol ivame ukukhethwa ngenxa yamandla ayo amakhulu. Kodwa-ke, nge-croup ethambile ezinganeni noma izimpawu ze-bronchitis ngezikhathi ezithile, i-racepinephrine ingase ilunge ngokuphelele futhi ibangele imiphumela emibi embalwa.

Abantu abaningi abane-asthma engapheli basebenzisa i-albuterol njenge-inhaler yabo eyinhloko yokuhlenga kodwa bangase baphendukele ku-racepinephrine ngamalungu omndeni anezimpawu ezithambile ngezikhathi ezithile. Ukukhetha kuvame ukuncika ekuqineni kwezimpawu, imvamisa yokusetshenziswa, nokuthi ngabe udinga ukwelashwa ngamandla kadokotela.

Imibuzo Evame Ukubuzwa Mayelana ne-Racepinephrine

Ingabe i-Racepinephrine iphephile ezigulini zenhliziyo?

I-Racepinephrine kufanele isetshenziswe ngokucophelela uma unesifo senhliziyo, futhi kufanele uthintane nodokotela wakho ngaphambi kokuyisebenzisa. Umuthi ungakhuphula izinga lokushaya kwenhliziyo nomfutho wegazi, okungase kuqede uhlelo lwe-cardiovascular oluvele lonakele.

Uma unezimo zenhliziyo ezithambile, ezinzile futhi udokotela wakho ekugunyaza, i-racepinephrine ingase isaphephile ukusetshenziswa ngezikhathi ezithile. Kodwa-ke, abantu abanezifo zenhliziyo ezinzima, ukuhlaselwa yinhliziyo kwakamuva, noma ama-arrhythmias ayingozi ngokuvamile kufanele bayigweme ngokuphelele.

Udokotela wakho wenhliziyo angasiza ekutholeni ukuthi izinzuzo zokuphefumula zidlula yini izingozi zenhliziyo esimweni sakho esithile. Bangase batusa ukuqapha inhliziyo noma baphakamise ezinye izindlela eziphephile zokuphatha izimpawu zakho zokuphefumula.

Kufanele Ngenzeni Uma Ngisebenzisa I-Racepinephrine Eningi Ngengozi?

Uma usebenzise i-racepinephrine eningi kunokunconywayo, ungesabi, kodwa ziqaphele ngokucophelela amahora ambalwa alandelayo. Izimpawu zokweqisa imithamo ngokuvamile zihlanganisa ukushaya kwenhliziyo okusheshayo kakhulu, ukuthuthumela okukhulu, ubuhlungu besifuba, noma ukuzizwa ukhathazeke kakhulu.

Okokuqala, hlala phansi bese uzama ukuzola. Phuza amanzi athile futhi ugweme i-caffeine noma ezinye izinto ezikhuthazayo. Abantu abaningi bayalulama ekweqiseni imithamo ethambile phakathi kwamahora angu-2-4 njengoba umuthi usuphela ngokwemvelo.

Funani ukunakekelwa kwezempilo ngokushesha uma uhlangabezana nobuhlungu besifuba obukhulu, izinga lenhliziyo elingaphezu kwama-120 ngomzuzu, ubunzima bokuphefumula obubi kakhulu kunangaphambi kokwelashwa, noma izimpawu zokukhathazeka okukhulu noma ukwethuka. Amagumbi eziphuthumayo ahlome kahle ukuphatha ukweqisa imithamo ye-bronchodilator.

Ukuze uthole ireferensi yesikhathi esizayo, hlala ulinganisa imithamo ngokucophelela futhi ulinde okungenani amahora angu-3-4 phakathi kokwelashwa ngaphandle uma uqondiswe ngokuqondile ngenye indlela ngumhlinzeki wezempilo.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Racepinephrine?

Ngokungafani nemithi yansuku zonke, i-racepinephrine isetshenziswa njengoba kudingeka ngezimpawu, ngakho-ke akukho hlelo olujwayelekile okufanele lulondolozwe. Uma unezinkinga zokuphefumula, ungalusebenzisa noma nini lapho izimpawu zenzeka, ulandela izinkomba zephakheji.

Ungazami ukuthi "ubambe" ngokuthatha imithamo eyengeziwe uma uzizwa sengathi uphuthelwe ithuba lokuyisebenzisa ngaphambili. Esikhundleni salokho, thatha umthamo wakho olandelayo uma empeleni uwudinga ngezinkinga zokuphefumula.

Uma usebenzisa i-racepinephrine njalo izinsuku eziningana futhi ukhohlwa umthamo obekiwe, vele uqhubeke nendlela yakho ejwayelekile lapho izimpawu zibuyela. Umuthi usebenza kahle kakhulu uma usetshenziswa ekuphenduleni ubunzima bokuphefumula bangempela kunokuba ngohlelo oluqinile.

Ngingayeka nini ukuthatha i-Racepinephrine?

Ungayeka ukuthatha i-racepinephrine ngokushesha nje lapho izimpawu zakho zokuphefumula zithuthuka futhi ungasadingi ukukhululeka. Ngokungafani neminye imithi, asikho isidingo sokuyeka kancane noma ukunciphisa umthamo kancane kancane.

Abantu abaningi ngokwemvelo bayayeka ukuyisebenzisa lapho i-croup yabo, i-bronchitis, noma esinye isimo sokuphefumula silungiswa. Lokhu kuvamile ukwenzeka phakathi kwezinsuku ezi-3-7 ezimweni ezinzima.

Uma ubulokhu usebenzisa i-racepinephrine njalo isikhathi esingaphezu kwesonto elilodwa, noma uma izimpawu zakho ziqhubeka zibuyela, sekuyisikhathi sokubona umhlinzeki wezempilo. Ungase udinge indlela ehlukile yokwelapha noma ukuhlolwa kwezimo ezingaphansi ezidinga ukuphathwa kwemithi kadokotela.

Ngingayisebenzisa i-Racepinephrine neminye imithi?

I-Racepinephrine ingasebenzisana neminye imithi ethile, ikakhulukazi lezo ezithinta inhliziyo yakho noma uhlelo lwakho lwezinzwa. Hlala uhlola nomuthi noma udokotela ngaphambi kokuyihlanganisa nezinye izindlela zokwelapha.

Qaphela ikakhulukazi uma uthatha imithi yenhliziyo, imithi yokwehlisa umfutho wegazi, ama-antidepressants, noma eminye imithi ye-asthma. Ezinye izinhlanganisela zingakhuphula imiphumela emibi noma zinciphise ukusebenza kahle.

Imithi etholakala ngaphandle kwemvume kadokotela efana nama-decongestants, amaphilisi e-caffeine, noma izithasiselo zokudla nazo zingathuthukisa imiphumela ye-stimulant ye-racepinephrine. Uma ungabaza, buza usokhemisi wakho mayelana nokusebenzisana okungenzeka - bangochwepheshe ekuhlonzeni izinhlanganisela ezinzima.