Ramucirumab (indlela ye-intravenous)

Cyramza

I-Ramucirumab injection isetshenziswa yodwa noma kanye ne-paclitaxel ukwelapha umdlavuza wesisu noma umdlavuza we-gastroesophageal junction (GEJ) ophambili noma oseduze (umdlavuza osekuye wasakazeka) ngemva kokuthi isiguli samukele eminye imithi yomdlavuza (isib. imithi ehlanganisa i-fluoropyrimidine noma i-platinum) kodwa ayisebenzi kahle. I-Ramucirumab injection isetshenziswa futhi kanye ne-erlotinib njengokwelashwa kokuqala komdlavuza olukhulu lwamaseli emithambo-mpilo (NSCLC) oseduze (umdlavuza osekuye wasakazeka) kubantu abanezinye izinhlobo ze-epidermal growth factor receptor (EGFR) gene engavamile (ukususa i-exon 19 noma ukuguqulwa kwe-exon 21). Udokotela wakho uzokwenza ivivi ngaphambi kokuthi uthathe le mithi. I-Ramucirumab injection isetshenziswa futhi kanye ne-docetaxel ukwelapha umdlavuza olukhulu lwamaseli emithambo-mpilo (NSCLC) oseduze (umdlavuza osekuye wasakazeka) kubantu abamukele eminye imithi yomdlavuza (isib. imithi ehlanganisa i-platinum). Inikezwa kubantu abanezinhlungu ezinengxaki ye-EGFR noma i-ALK gene futhi baye bazama ukwelashwa kwezinhlungu kodwa ayisebenzi kahle. I-Ramucirumab injection isetshenziswa futhi kanye ne-folinic acid, i-5-fluorouracil, ne-irinotecan (FOLFIRI) ukwelapha umdlavuza we-colorectal oseduze (mCRC) kubantu abamukele eminye imithi yomdlavuza (isib. i-bevacizumab, i-oxaliplatin, noma imithi ehlanganisa i-fluoropyrimidine) kodwa ayisebenzi kahle. I-Ramucirumab injection isetshenziswa futhi ukwelapha uhlobo lomdlavuza wesibindi oluthiwa yi-hepatocellular carcinoma (HCC) kubantu abamukele eminye imithi (isib. i-sorafenib). Le mithi kufanele inikezwe kuphela yi- noma ngaphansi kokunakekelwa okuqondile kuka-dokotela wakho. Lo mkhiqizo uyatholakala ngezindlela zokulinganisa ezilandelayo:

Uma kunqunywe ukuthi kusetshenziswe iyeza, izingozi zokuthatha leliyeza kufanele ziqhathaniswe nezinzuzo elizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Kuleliyeza, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqakathekile noma oluhambisana nokwaleka kuleliyeza noma kwezinye izidakamizwa. Tshela futhi ochwepheshe bakho bezempilo uma unanoma yiluphi olunye uhlobo lwezinto ozaleka kuzo, njengokudla, izibenge, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ukuhlola ubudlelwano phakathi nobudala nemiphumela yokubeka i-ramucirumab kubantwana. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-ramucirumab kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma kusetshenziswa leliyeza ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha leliyeza ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo izidakamizwa ezimbili ezahlukene zingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungase kudingeke. Tshela ochwepheshe bakho bezempilo uma uthatha noma iyiphi enye imithi yokuqaphela noma engekho ngaphansi kwelayisensi (over-the-counter [OTC]). Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla ngoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba ngezinye izidakamizwa kungase futhi kubangele ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kweyeza lakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwaleliyeza. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi: