Yini i-Ranolazine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Ranolazine ngumuthi kadokotela osiza abantu abanezinhlungu zesifuba ezingamahlala-khona (i-angina) ukulawula izimpawu zabo futhi bathuthukise izinga lempilo yabo. Isebenza ngendlela ehlukile kweminye imithi yenhliziyo ngokusiza imisipha yenhliziyo yakho ukuthi isebenzise umoya-mpilo ngempumelelo enkulu, okunganciphisa ukuvama nobukhulu bezigameko zokuzwa izinhlungu esifubeni.

Lo muthi ungowodwa ohlukile wemithi engayithinti izinga lokushaya kwenhliziyo yakho noma umfutho wegazi njengemithi ejwayelekile ye-angina. Esikhundleni salokho, isiza inhliziyo yakho ukuthi isebenze kangcono ezingeni leselula, okuyenza ibe yindlela ewusizo kubantu abadinga ukusekelwa okwengeziwe ngaphezu kokwelashwa okujwayelekile.

Isetshenziselwani i-Ranolazine?

I-Ranolazine ikakhulukazi inikezwa ukwelapha i-angina engamahlala-khona, okuyizinhlungu zesifuba eziphindaphindayo ezibangelwa ukuncipha kokugeleza kwegazi emsipheni wenhliziyo yakho. Udokotela wakho angase ancome lo muthi uma uqhubeka nokuzwa izinhlungu esifubeni naphezu kokuthatha eminye imithi yenhliziyo efana nama-beta-blockers noma ama-calcium channel blockers.

Lo muthi usiza ukunciphisa ukuthi uvame kangakanani ukuzwa izigameko ze-angina futhi ungathuthukisa ikhono lakho lokwenza imisebenzi yansuku zonke ngaphandle kokungakhululeki esifubeni. Ilusizo ikakhulukazi kubantu abanezinhlungu zesifuba ezingalawulwa ngokugcwele ngohlelo lwabo lwamanje lokwelashwa.

Abanye odokotela bangase futhi banikeze i-ranolazine ngezinkinga ezithile zokushaya kwenhliziyo, nakuba lokhu kungavamile. Umhlinzeki wakho wezempilo uzonquma ukuthi lo muthi ulungele yini isimo sakho senhliziyo esithile kanye nesimo sempilo yakho esiphelele.

Isebenza kanjani i-Ranolazine?

I-Ranolazine isebenza ngokuvimba iziteshi ezithile ze-sodium emangqamuzaneni emisipha yenhliziyo yakho, okuyisiza ukuthi isebenzise umoya-mpilo ngempumelelo enkulu ngezikhathi zokucindezeleka noma ukuncipha kokugeleza kwegazi. Lokhu kwehluke ngendlela esebenza ngayo eminye imithi yenhliziyo, okuyenza ibe yisengezo esiyingqayizivele ohlelweni lwakho lokwelashwa.

Kucabange njengokusiza imisipha yenhliziyo yakho ukuthi isebenzise kangcono umoya-mpilo ewutholayo, kunokwandisa ukugeleza kwegazi noma ukushintsha izinga lokushaya kwenhliziyo yakho. Le ndlela yenza inhliziyo yakho ikwazi ukumelana uma ukugeleza kwegazi kuncipha okwesikhashana, okuyilokho okubangela ubuhlungu be-angina.

Umuthi uthathwa njengomuthi onamandla ngokulinganiselwe futhi ngokuvamile usebenza kungakapheli amahora ambalwa ngemva kokuwuthatha. Nokho, cishe uzodinga ukuwuthatha amasonto amaningana ukuze uthole izinzuzo zawo ezigcwele zokunciphisa izigameko zobuhlungu besifuba.

Kufanele Ngiyithathe Kanjani I-Ranolazine?

Thatha i-ranolazine ngendlela eqondile njengoba uyalelwe udokotela wakho, ngokuvamile kabili ngosuku ngaphandle kokudla noma ngaphandle kokudla. Gwinya amaphilisi wonke ngaphandle kokuwachoboza, ukuwahlafuna, noma ukuwaqhekeza, njengoba aklanyelwe ukukhipha umuthi kancane kancane usuku lonke.

Ungawuthatha lo muthi ngesikhathi sokudla uma kukusiza ukuthi ukhumbule imithamo yakho noma uma uzwa isisu esibuhlungu. Akukho ukudla okuthile okudingekayo, kodwa ukuhlala unokulinganisela ngesikhathi sakho kusiza ukugcina amazinga omuthi aqinile ohlelweni lwakho.

Uma uphuza ijusi yama-grapefruit njalo, khuluma nodokotela wakho kuqala, njengoba ingakhuphula amazinga e-ranolazine egazini lakho futhi ingase ibangele imiphumela emibi. Amanzi ayisinqumo esingcono kakhulu sokuthatha umuthi wakho.

Setha isikhumbuzi sansuku zonke noma thatha imithamo yakho ngezikhathi ezifanayo nsuku zonke ukuze usize ukusungula umkhuba. Abantu abaningi bakuthola kuwusizo ukuthatha umthamo wabo wasekuseni ngesidlo sasekuseni kanye nomthamo wabo wakusihlwa ngesidlo sakusihlwa.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Ranolazine?

I-Ranolazine ngokuvamile iyimithi yesikhathi eside ozoqhubeka uyithatha uma nje isiza ukulawula ubuhlungu besifuba sakho futhi ungaqali ukuzwa imiphumela emibi enezinkinga. Abantu abaningi abane-angina engapheli badinga ukwelashwa okuqhubekayo ukuze bagcine ukulawulwa kwezimpawu zabo.

Udktela wakho uzoqapha ukuthi umzimba wakho usabela kanjani emuthini futhi angase alungise umthamo wakho ezinyangeni zokuqala zokwelashwa. Abanye abantu baqaphela ukuthuthuka ngesonto lokuqala, kanti abanye bangase badinge amasonto amaningana ukuze bathole izinzuzo eziphelele.

Ungayeki ukuthatha i-ranolazine ngokuzumayo ngaphandle kokubonisana nodokotela wakho, ngisho noma uzizwa ungcono. Izimpawu zobuhlungu besifuba zingase zibuye, futhi ukuyeka ngokuphazima kungase kubangele isimo sakho sibe sibi okwesikhashana.

Ukuqokwa okulandelayo njalo kuzosiza ithimba lakho lezempilo ukuthi linqume ukuthi umuthi uyaqhubeka yini ukuba yisinqumo esifanele sempilo yenhliziyo yakho kanye nenhlalakahle iyonke.

Yiziphi Imiphumela Eceleni ye-Ranolazine?

Abantu abaningi bayayibekezelela kahle i-ranolazine, kodwa njengayo yonke imithi, ingabangela imiphumela emibi kwabanye abantu. Izindaba ezinhle ukuthi imiphumela emibi engathí sina ayivamile, futhi imiphumela eminingi emibi emincane iyathuthuka njengoba umzimba wakho ujwayela umuthi.

Imiphumela emibi evamile ethinta abanye abantu ihlanganisa:

• Isiyezi noma ukukhathala, ikakhulukazi uma usukuma
• Isicanucanu noma ukungakhululeki kwesisu
• Ikhanda
• Ukuqunjelwa
• Ukuzwa ukhathele noma ubuthakathaka

Lezi zimpawu zivame ukuba mnene futhi zivame ukuthuthuka emasontweni ambalwa okuqala okwelashwa. Ukuthatha umuthi wakho nokudla kungasiza ekunciphiseni isicanucanu, futhi ukuhlala unamanzi kahle kungasiza ekuqunjelweni.

Imiphumela emibi engavamile kodwa engathí sina idinga ukunakekelwa kwezempilo ngokushesha. Xhumana nodokotela wakho ngokushesha uma uhlangabezana nokushaya kwenhliziyo okungajwayelekile, isiyezi esikhulu, ukuquleka, noma yiziphi izimpawu ezingavamile ezikukhathazayo.

Abanye abantu bangase babe nemiphumela emibi engavamile efana nezinkinga zezinso noma izinguquko ekusebenzeni kwesibindi, yingakho udokotela wakho ezokuqapha ngezivivinyo zegazi ngezikhathi ezithile, ikakhulukazi uma uqala umuthi.

Ubani Ongafanele Athole I-Ranolazine?

IRanolazine ayifanele wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Abantu abanezinkinga ezithile zesibindi noma isifo esibi sezinso ngokuvamile akufanele bathathe lo muthi ngoba imizimba yabo ingase ingawuqedi kahle.

Kufanele ugweme i-ranolazine uma unezinkinga ezithile zesigqi senhliziyo, ikakhulukazi isimo esibizwa ngokuthi i-QT prolongation, esingatholakala ku-electrocardiogram (ECG). Udokotela wakho cishe uzoqhuba izivivinyo zenhliziyo ngaphambi kokuqala ukukunika lo muthi.

Uma uthatha imithi ethile engase ihlangane ne-ranolazine, udokotela wakho angase akhethe enye indlela yokwelapha. Lokhu kufaka phakathi ama-antibiotics athile, imithi elwa nesikhunta, kanye nemithi esetshenziselwa ukwelapha i-HIV noma ukucindezeleka.

Abesifazane abakhulelwe nabancelisayo kufanele baxoxe ngezingozi nezinzuzo nomhlinzeki wabo wezempilo, njengoba ukuphepha kwe-ranolazine ngesikhathi sokukhulelwa kungakahlolisiswa ngokugcwele. Udokotela wakho uzokusiza ukuthi ulinganise izinzuzo ezingaba khona nezingozi ezingase zibe khona.

Amagama Omkhiqizo we-Ranolazine

I-Ranolazine ivame kakhulu ukutholakala ngaphansi kwegama lomkhiqizo elithi Ranexa e-United States. Lena yifomula yokukhishwa okwandisiwe odokotela abaningi abayinqumayo yokwelashwa kwe-angina engapheli.

Izinhlobo ezivamile ze-ranolazine nazo ziyatholakala, eziqukethe isithako esifanayo esisebenzayo kodwa zingase zibe ngentengo ephansi. Umuthi wakho wezidakamizwa angakusiza ukuthi uqonde ukuthi ingabe inguqulo ejwayelekile iyatholakala futhi ifanele imiyalelo yakho.

Njalo qiniseka ukuthi uthatha umkhiqizo ofanayo noma inguqulo ejwayelekile ngokuqhubekayo, njengoba ukushintsha phakathi kwabakhiqizi abahlukene ngaphandle kolwazi lukadokotela wakho kungase kuthinte ukuthi umuthi usebenza kahle kangakanani kuwe.

Ezinye izindlela ze-Ranolazine

Uma i-ranolazine ingakulungele noma ingalawuli kahle ubuhlungu bakho besifuba, imithi eminingi ehlukile iyatholakala. Udokotela wakho angase acabange ngeminye imithi elwa ne-angina efana ne-nitrates esebenza isikhathi eside, ama-calcium channel blockers, noma ama-beta-blockers.

Imithi emisha efana ne-ivabradine ingase ibe yizinketho kwabanye abantu, ikakhulukazi labo abangakwazi ukubekezelela ama-beta-blockers. Abanye abantu bayazuza ekwelashweni okuhlanganisiwe besebenzisa imithi eminingi ukuze bathole ukulawulwa okungcono kwezimpawu.

Izindlela ezingezona zemithi nazo zingagcwalisa uhlelo lwakho lokwelapha. Lokhu kungase kuhlanganise izinhlelo zokuvuselela inhliziyo, amasu okulawula ukucindezeleka, izinguquko zokudla, kanye nokwanda kancane komsebenzi womzimba ngaphansi kokuqondiswa kwezokwelapha.

Udokotela wakho wezifo zenhliziyo uzosebenza nawe ukuze athole inhlanganisela yokwelapha esebenza kahle kakhulu ngokusekelwe ezimpawini zakho ezithile, ezinye izimo zempilo, nokuthi ukubekezelela kahle kangakanani imithi ehlukene.

Ingabe i-Ranolazine Ingcono Kune-Nitroglycerin?

I-Ranolazine ne-nitroglycerin zisebenzela izinjongo ezihlukene ekwelapheni i-angina, ngakho-ke azifaniswa ngokuqondile. I-Nitroglycerin ivame ukusetshenziselwa ukukhulula ngokushesha izigameko zobuhlungu besifuba obukhulu, kuyilapho i-ranolazine ithathwa nsuku zonke ukuvimbela ubuhlungu besifuba ukuthi bungenzeki.

Abantu abaningi basebenzisa le mithi yomibili njengengxenye yohlelo lwabo olubanzi lokuphatha i-angina. I-Ranolazine isiza ukunciphisa imvamisa yezigameko zobuhlungu besifuba, kuyilapho i-nitroglycerin inikeza ukukhululeka okusheshayo lapho ubuhlungu obuqhubekayo buvela.

I-Ranolazine inikeza inzuzo yokungathinti umfutho wegazi lakho noma izinga lokushaya kwenhliziyo njenge-nitroglycerin, okwenza ifaneleke kubantu ababa nesiyezi noma umfutho wegazi ophansi ngeminye imithi.

Udokotela wakho uzokusiza ukuthi uqonde ukuthi le mithi isebenza kanjani ndawonye nokuthi iyiphi indlela yokuhlanganisa engase isebenze kahle kakhulu esimweni sakho esithile nezidingo zokuphila.

Imibuzo Evame Ukubuzwa Mayelana ne-Ranolazine

Umbuzo 1. Ingabe i-Ranolazine Iphephile Kubantu Abanesifo Sikashukela?

Yebo, i-ranolazine ngokuvamile iphephile kubantu abanesifo sikashukela futhi ngokuvamile ayithinti amazinga kashukela egazini. Eqinisweni, ezinye izifundo zikhomba ukuthi ingaba nemiphumela engathathi hlangothi noma ezinenzuzo encane ekulawuleni ushukela wegazi, nakuba lokhu kungewona umgomo wayo oyinhloko.

Uma unesifo sikashukela, udokotela wakho uzokuhlola ngokucophelela lapho uqala i-ranolazine, njengoba benza nganoma imuphi umuthi omusha. Qhubeka nokuhlola ushukela wakho wegazi njengoba kunconywe futhi wazise ithimba lakho lezempilo uma ubona izinguquko emaphethini akho e-glucose.

Umbuzo 2. Kufanele Ngenzeni Uma Ngithatha I-Ranolazine Eningi Ngengozi?

Uma ngengozi uthatha i-ranolazine eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ikakhulukazi uma uhlangabezana nezimpawu ezinjengokuquleka okukhulu, isicanucanu, noma ukushaya kwenhliziyo okungajwayelekile. Ungalindi ukubona ukuthi izimpawu ziyavela yini.

Ukuthatha imithamo emibili ngezikhathi ezithile akunakwenzeka ukuthi kubangele ukulimala okukhulu, kodwa kubalulekile ukuthola iseluleko sezokwelapha. Udokotela wakho angase afune ukuqapha isigqi senhliziyo yakho nezinye izimpawu ezibalulekile ukuze aqinisekise ukuthi uphephile.

Umbuzo 3. Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Ranolazine?

Uma uphuthelwa umthamo we-ranolazine, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kuleso simo, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, njengoba lokhu kungandisa ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi ukukusiza ukuthi uhlale emkhondweni.

Umbuzo 4. Ngingayeka Nini Ukuthatha I-Ranolazine?

Yeka kuphela ukuthatha i-ranolazine lapho udokotela wakho ekweluleka ukuba wenze njalo. Lo muthi ngokuvamile usetshenziswa isikhathi eside ukuze kulawulwe i-angina engapheli, futhi ukuyeka kungazelelwe kungabangela ukuthi izimpawu zakho zobuhlungu besifuba zibuye noma zibe zimbi.

Udkt wakho uzohlola njalo ukuthi i-ranolazine iyaqhubeka yini ukuba yinzuzo kuwe futhi angase alungise uhlelo lwakho lokwelashwa ngokusekelwe endleleni ozabela ngayo kanye nanoma yiziphi izinguquko esimweni sakho sempilo yonke.

Q5. Ngingakwazi yini ukuzivocavoca ngenkathi ngithatha i-Ranolazine?

Yebo, i-ranolazine ingakusiza ngempela ukuthi uzivocavoce ngokunethezeka ngokunciphisa izigameko zobuhlungu besifuba ngesikhathi somsebenzi womzimba. Kodwa-ke, kufanele usebenze nodokotela wakho ukuze uthuthukise uhlelo lokuzivocavoca olufanele oluhambisana nezinga lakho lamanje lokufaneleka kanye nesimo senhliziyo.

Qala kancane futhi wandise kancane izinga lakho lomsebenzi njengoba kutholakala. Abantu abaningi bathola ukuthi bangenza imisebenzi eminingi ngobuhlungu obuncane besifuba uma i-ranolazine iqala ukusebenza ngempumelelo, kodwa ngaso sonke isikhathi lalela umzimba wakho futhi ume uma unezimpawu.