Yini i-Regadenoson: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Regadenoson iyimithi esiza odokotela ukuthi babone ukuthi inhliziyo yakho isebenza kahle kangakanani ngesikhathi sokuhlolwa okukhethekile kokuthwebula izithombe. Inikezwa ngomjovo we-IV (intravenous) ukuze kwandiswe okwesikhashana ukugeleza kwegazi enhliziyweni yakho, okwenza kube lula ochwepheshe bezokwelapha ukubona noma yiziphi izinkinga ekuhlinzekweni kwegazi lenhliziyo yakho.

Le mithi yenzelwe ngqo ukuhlolwa kokucindezeleka kwenhliziyo uma ungenakwazi ukuzivocavoca ku-treadmill noma ibhayisikili elinganyakazi. Cabanga ngayo njengendlela yokuthi "uhlolisise ukucindezeleka" kwenhliziyo yakho ngaphandle komsebenzi womzimba, unikeze udokotela wakho ulwazi olubalulekile ngempilo yenhliziyo yakho endaweni ephephile, elawulwayo.

Isetshenziselwani i-Regadenoson?

I-Regadenoson isetshenziselwa ikakhulukazi ukuthwebula izithombe ze-myocardial perfusion, okuyigama elihle lokuthatha izithombe ezinemininingwane yokugeleza kwegazi emsipheni wenhliziyo yakho. Udokotela wakho angase ancome lolu vivinyo uma uhlangabezana nobuhlungu besifuba, ukuphefumula kanzima, noma ezinye izimpawu ezisikisela izinkinga zenhliziyo ezingaba khona.

Le mithi ilusizo ikakhulukazi kubantu abangakwazi ukwenza izivivinyo zokucindezeleka zendabuko. Lokhu kuhlanganisa abantu abane-arthritis, izinkinga zamaphaphu, noma ezinye izimo ezenza ukuzivocavoca umzimba kube nzima noma kungaphephile ngesikhathi sokuhlolwa.

Ngesikhathi senqubo, i-regadenoson ilingisa okwesikhashana imiphumela yokuzivocavoca enhliziyweni yakho. Lokhu kuvumela odokotela ukuthi babone ukuthi inhliziyo yakho isabela kanjani ekwandeni kwesidingo somoya-mpilo nokugeleza kwegazi, okubasiza ukuthi bathole imithambo evaliwe noma encishisiwe.

Isebenza Kanjani i-Regadenoson?

I-Regadenoson isebenza ngokugxila kuma-receptors athile enhliziyweni yakho abizwa ngokuthi ama-adenosine A2A receptors. Uma ibopha kula ma-receptors, ibangela ukuthi imithambo yakho ye-coronary (imithambo yegazi enikeza inhliziyo yakho) yande noma yandise kakhulu.

Lo mphumela wokwandisa ukuhamba kwegazi ukhuphula ukuhamba kwegazi ezingxenyeni ezinempilo zomzimba wakho wenhliziyo ngenkathi izindawo ezinemithambo evalekile noma enciphile zithola ukuhamba kwegazi okuncane. Umehluko phakathi kwalezi zindawo uvela ngokucacile ekuskeneni kwezithombe, okusiza udokotela wakho ukuthi abone izindawo ezinzima.

Umuthi ubhekwa njenge-vasodilator ekhethiwe futhi eqinile ye-coronary. Yenzelwe ukusebenza ngokushesha nangempumelelo, nemiphumela evame ukuhlala imizuzu embalwa nje ngemuva komjovo.

Kufanele Ngiyithathe Kanjani I-Regadenoson?

Ngeke empeleni uzithathele wena i-regadenoson - ngaso sonke isikhathi inikezwa ochwepheshe bezempilo abaqeqeshiwe endaweni yezokwelapha. Umuthi uza njengomjovo olungiselelwe ukusetshenziswa onikezwa ngomugqa we-IV engalweni yakho.

Ngaphambi kokuhlolwa kwakho, udokotela wakho cishe uzokucela ukuthi ugweme i-caffeine amahora angu-12 kuya kwangu-24. Lokhu kuhlanganisa ikhofi, itiye, ushokoledi, nezinye iziphuzo ezithambile, njengoba i-caffeine ingaphazamisa indlela i-regadenoson esebenza ngayo emzimbeni wakho.

Ngokuvamile uzocelwa ukuthi uzile ukudla amahora ambalwa ngaphambi kokuhlolwa, nakuba ngokuvamile ungaphuza amanzi. Ithimba lakho lezempilo lizokunikeza imiyalelo ethile esekelwe esimweni sakho ngasinye kanye nohlobo lwesithombe olwenziwayo.

Umjovo ngokwawo uthatha imizuzwana engaba ngu-10 kuphela, kulandelwe ngokushesha ukukhuhla kwe-saline ukuqinisekisa ukuthi wonke umuthi ufika ngokushesha nangempumelelo emgudwini wakho wegazi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Regadenoson?

I-Regadenoson akuyona imithi oyithatha njalo noma isikhathi eside. Kungumjovo owodwa onikezwa ngokuqondile ngesikhathi senqubo yakho yokuhlolwa kwengcindezi yenhliziyo.

Imiphumela ye-regadenoson iqala ngemizuzwana ngemuva komjovo futhi ivame ukuhlala imizuzu engaba ngu-2 kuya kwangu-4. Kodwa-ke, abanye abantu bangase bazizwe imiphumela eqhubekayo imizuzu engaba ngu-15 ngemuva komjovo.

Uzoqhubeka usefasilitini lezokwelapha ukuze uqashwe okungenani imizuzu engama-15 kuya kwengama-30 ngemuva komjovo ukuqinisekisa ukuthi uzizwa kahle ngaphambi kokuhamba. Ithimba lakho lezempilo lizokuqapha ngalesi sikhathi.

Yiziphi Imiphumela Eceleni ye-Regadenoson?

Abantu abaningi bahlangabezana nemiphumela ethile eceleni evela ku-regadenoson, kodwa imvamisa iba mnene futhi ihlala isikhashana. Imiphumela evame kakhulu eceleni yenzeka ngoba umuthi uthinta ukugeleza kwegazi emzimbeni wakho wonke, hhayi nje inhliziyo yakho.

Nansi imiphumela eceleni ongase uyithole ngesikhathi noma ngemuva nje komjovo wakho:

• Ukuphefumula kanzima noma ukuzwa sengathi awukwazi ukubamba umoya wakho
• Ukuphatheka kabi esifubeni noma umuzwa wokucindezela
• Ukubomvu noma ukufudumala ebusweni nasentanyeni yakho
• Ikhanda
• Isiyezi noma ukuzwa sengathi uyakhathala
• Isicanucanu
• Ukunambitheka kwensimbi emlonyeni wakho
• Umuzwa wokuqina komphimbo

Le miphumela ivamise ukushabalala ngemizuzu embalwa njengoba umuthi usuphela. Ithimba lakho lezempilo lizokuqapha eduze futhi linganikeza imithi ukusiza ukulwa nanoma yiziphi izimpawu ezingakhululekile uma kudingeka.

Imiphumela eceleni engathi sína kodwa engavamile ingabandakanya ukwehla okukhulu kwengcindezi yegazi, ubunzima obukhulu bokuphefumula, noma ukusabela komzimba. Nakuba kungavamile, lezi zimo zidinga ukunakekelwa kwezokwelapha ngokushesha, yingakho ukuhlolwa kwenziwa njalo esikhungweni sezokwelapha.

Abanye abantu abanesifuba somoya noma isifo esingamahlalakhona samaphaphu bangase bahlangabezane nobunzima bokuphefumula obuqinile. Uma unezimo ezinjalo, udokotela wakho uzohlola izinzuzo nezingozi ngokucophelela ngaphambi kokuncoma lokhu kuhlolwa.

Ubani Ongafanele Athole i-Regadenoson?

I-Regadenoson ayifanele wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuncoma lokhu kuhlolwa. Umuthi uvame ukugwenywa kubantu abanezinkinga ezithile zesigqi senhliziyo noma izimo ezinzima zokuphefumula.

Akufanele wamukele i-regadenoson uma une-angina engazinzile, okusho ubuhlungu besifuba obuya ngokuya buba bubi noma obenzeka lapho uphumule. Abantu abanezinhlobo ezithile zokuphazamiseka kwesigqi senhliziyo, ikakhulu labo ababandakanya uhlelo lukagesi lwenhliziyo, kungenzeka badinge nokugwema lo muthi.

Uma une-asthma ebucayi noma isifo sokuvinjelwa kwamaphaphu esingamahlalakhona (COPD), udokotela wakho uzodinga ukuhlola ukuthi i-regadenoson iphephile yini kuwe. Umuthi ngezinye izikhathi ungenza izinkinga zokuphefumula zibe zimbi kubantu abanezimo ezinjalo.

Abantu abanomfutho wegazi ophansi kakhulu kufanele baqaphele nge-regadenoson, njengoba ingabangela ukuthi umfutho wegazi wehle ngaphezulu. Ithimba lakho lezempilo lizogada umfutho wakho wegazi ngokusondelene ngaphambi nangenkathi yenqubo.

Abesifazane abakhulelwe ngokuvamile kufanele bagweme i-regadenoson ngaphandle uma izinzuzo zicacile ukuthi zidlula izingozi. Uma uncelisa, udokotela wakho angase ancome ukuyeka ukuncelisa okwesikhashana amahora ayi-10 kuya kwayi-12 ngemuva komjovo.

Amagama e-Brand e-Regadenoson

I-Regadenoson ivame ukwaziwa ngegama layo le-brand elithi Lexiscan e-United States. Leli yigama eliyinhloko le-brand ozolizwa ezikhungweni zezokwelapha nasemsebenzini obhalwe ngokuqondene nokuhlolwa kwakho kokucindezeleka.

Umuthi ungase utholakale ngaphansi kwamagama e-brand ahlukene kwamanye amazwe, kodwa i-Lexiscan ihlala iyigama elaziwa kakhulu le-regadenoson eNyakatho Melika.

Ezinye izindlela ze-Regadenoson

Uma i-regadenoson ingakulungele, udokotela wakho unezinye izinketho eziningana zokuhlola ukucindezeleka kwenhliziyo. Enye nanye indlela esikhundleni isebenza ngendlela ehlukile futhi ingase ifaneleke kakhulu ngokuya ngesimo sakho sezokwelapha esithile.

I-Adenosine ngomunye umuthi osebenza ngendlela efana ne-regadenoson kodwa idinga ukufakwa kwe-IV okude kunomjovo owodwa. Abanye abantu bayayibekezelela kangcono i-adenosine, kanti abanye bakhetha ubude obufushane be-regadenoson.

I-Dipyridamole iyikhambi elidala eliphinde landise ukuhamba kwegazi enhliziyweni ngenjongo yokuthwebula izithombe. Linikezwa njenge-IV infusion ngemizuzu embalwa futhi lingahlanganiswa nokuzivocavoca uma ukwazi ukuhamba ku-treadmill.

I-Dobutamine ngezinye izikhathi isetshenziswa njengenye indlela, ikakhulukazi kubantu abangakwazi ukuthola eminye imithi. Isebenza ngokwenza inhliziyo yakho ishaye ngokushesha futhi iqine kunokuthi ivule imithambo yegazi.

Udokotela wakho uzokhetha inketho engcono kakhulu ngokusekelwe emlandweni wakho wezokwelapha, imithi yamanje, kanye nezimo zempilo ezithile.

Ingabe i-Regadenoson ingcono kune-Adenosine?

Kokubili i-regadenoson ne-adenosine ziyasebenza ekuhlolweni kokucindezeleka kwenhliziyo, kodwa zinezinye izinto ezibalulekile ezingenza enye ifaneleke kakhulu kuwe kunenye.

I-Regadenoson inikeza lula komjovo owodwa, osheshayo othatha imizuzwana eyi-10 kuphela ukuwunikeza. Lokhu kushesha kakhulu kune-adenosine, edinga i-IV infusion eqhubekayo yemizuzu emi-4 kuya kwemi-6.

Abantu abaningi bathola ukuthi imiphumela emibi ye-regadenoson iyabekezeleleka kakhulu ngoba ivame ukuba ngaphansi futhi ihlale isikhathi esifushane. I-Adenosine ivame ukubangela ukungakhululeki okukhulu esifubeni nobunzima bokuphefumula ngesikhathi sokufakwa isikhathi eside.

Nokho, i-adenosine isetshenziswe ekuhlolweni kokucindezeleka kwenhliziyo isikhathi eside kune-regadenoson, ngakho kunemininingwane yesikhathi eside mayelana nokuphepha kwayo nokusebenza kahle. Ezinye izazi zezifo zenhliziyo zikhetha i-adenosine ngoba zingayeka ukufakwa ngokushesha uma kwenzeka imiphumela emibi engathi sína.

Ukukhetha phakathi kwale mithi kuvame ukwehla esimweni sakho sezokwelapha, ulwazi lukadokotela wakho kanye nokukhetha, nokuthi yini etholakalayo endaweni yakho yokuhlola.

Imibuzo Evame Ukubuzwa Mayelana ne-Regadenoson

Ingabe i-Regadenoson iphephile kubantu abanesifo sikashukela?

Yebo, i-regadenoson ngokuvamile iphephile kubantu abanesifo sikashukela. Umuthi awuthinti ngokuqondile amazinga kashukela egazini, ngakho ngeke kubangele i-glucose yakho ukuthi ikhuphuke noma yehle ngesikhathi sokuhlolwa.

Kodwa-ke, uma usebenzisa imithi yesifo sikashukela, udokotela wakho angase akunike imiyalelo ethile mayelana nesikhathi sokuthatha imithi yakho ngosuku lokuhlolwa kwakho, ikakhulukazi uma ucelwa ukuba uzile ngaphambi kwalokho. Njalo landela isiqondiso somhlinzeki wakho wezempilo mayelana nokuphatha imithi yakho yesifo sikashukela ngesikhathi senqubo.

Kufanele Ngenzeni Uma Ngamukela I-Regadenoson Eningi Ngengozi?

Akudingeki ukhathazeke ngokwamukela i-regadenoson eningi ngengozi ngoba ngaso sonke isikhathi inikezwa ochwepheshe bezempilo abaqeqeshiwe endaweni yezokwelapha elawulwayo. Umuthi uza ngemithamo elinganiselwe ngaphambili, futhi ithimba lakho lezempilo lilandela imithetho eqinile.

Uma bekukhona ukukhathazeka ngomthamo, ithimba lakho lezokwelapha lingaba nemithi efana ne-aminophylline etholakalayo ukuze ilwe nemiphumela ye-regadenoson ngokushesha. Leli elinye lamathuba okuphepha okuba nalolu vivinyo olwenziwa esikhungweni sezokwelapha.

Kufanele Ngenzeni Uma Ngiphuthelwa Ukuqokwa Kwami ​​Kwe-Regadenoson?

Njengoba i-regadenoson inikezwa ngesikhathi senqubo yezokwelapha ehleliwe, ukuphuthelwa ukuqokwa kwakho kusho ukuthi uzodinga ukuhlela kabusha ukuhlolwa kwakho kokucindezeleka kwenhliziyo. Xhumana nehhovisi likadokotela wakho noma isikhungo sokuthwebula izithombe ngokushesha ngangokunokwenzeka ukuze uhlele ukuqokwa okusha.

Ungakhathazeki nganoma yimiphumela yezokwelapha evela ekuphuthelweni ukuqokwa - impilo yakho ngeke ithintwe ukubambezeleka. Kodwa-ke, ukuhlela kabusha ngokushesha kuqinisekisa ukuthi uthola ukuhlolwa kwenhliziyo okutuswe udokotela wakho ngaphandle kokubambezeleka okungadingekile ekunakekelweni kwakho.

Ngingakwazi Nini Ukuqala Imisebenzi Ejwayelekile Ngemva Kwe-Regadenoson?

Abantu abaningi bangakwazi ukuqala imisebenzi ejwayelekile kungakapheli amahora ambalwa ngemva kokuthola i-regadenoson, uma sebeboniwe futhi bavunyelwe yithimba labo lezempilo. Ngokuvamile uzoqashwa imizuzu eyi-15 kuya kwengama-30 ngemva komjovo ukuze uqinisekise ukuthi uzizwa kahle.

Kufanele ugweme ukushayela ngemva nje kokuhlolwa uma uzizwa unesiyezi noma ukhathele. Kungumqondo omuhle ukuba othile akuqhubele ekhaya, ikakhulu uma usazizwa imiphumela ethile yemithi.

Ngokuvamile ungaqhubeka nokudla kwakho okuvamile nemithi ngemva nje kokuhlolwa, ngaphandle uma udokotela wakho ekunikeza imiyalelo ethile. Uma kwadingeka ukuthi uyeke ukusebenzisa i-caffeine ngaphambi kokuhlolwa, ungaqala ukuphuza ikhofi noma itiye uma inqubo isiqediwe.

Ngingayithatha imithi yami ejwayelekile ngosuku lokuhlolwa kwami ​​kwe-Regadenoson?

Ezimweni eziningi, ungaqhubeka nokuthatha imithi yakho ejwayelekile ngosuku lokuhlolwa kwakho kokucindezeleka kwe-regadenoson. Kodwa-ke, udokotela wakho angase akucele ukuthi uyeke okwesikhashana imithi ethile yenhliziyo engase iphazamise imiphumela yokuhlolwa.

Ama-beta-blockers kanye namanye ama-calcium channel blockers ngezinye izikhathi ayekiswa usuku noma ezimbili ngaphambi kokuhlolwa ngoba angathinta indlela inhliziyo yakho esabela ngayo ku-regadenoson. Umhlinzeki wakho wokunakekelwa kwezempilo uzokunikeza imiyalelo ethile mayelana nemithi okufanele uyiqhubeke nokuthi iyiphi okufanele uyeke okwesikhashana.

Ungalokothi uyeke ukuthatha imithi enqunyiwe ngaphandle kwemvume kadokotela wakho, ngisho noma ucabanga ukuthi ingase iphazamise ukuhlolwa. Njalo landela imiyalelo ethile enikezwe ithimba lakho lokunakekelwa kwezempilo.