Regorafenib (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Stivarga
Mayelana naleli khambi
I-Regorafenib isetshenziswa ekwelapheni umdlavuza osakazekile (umdlavuza osakazekile) wesisu kanye nesibindisi. Isetshenziswa kubantu abake baphathwa ngeminye imithi yomdlavuza engasebenzisanga kahle. I-Regorafenib ivikela ukukhula kwezimpukane. I-Regorafenib isetshenziswa futhi ekwelapheni i-tumors ye-gastrointestinal stromal (GIST) esakazekile kubantu abake bamukele eminye imithi engasebenzisanga kahle. I-GIST uhlobo lwemdlavuza oluyimfihlo oluthinta isisu, izisu, noma umgudu. Lolukhuni lusetshenziswa ekwelapheni uhlobo lwemdlavuza wesibindi oluthiwa yi-hepatocellular cancer (HCC) kubantu abake baphathwa yi-sorafenib. Lolukhuni lutholakala kuphela ngomyalelo wodokotela wakho. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Uma kunquma ukusebenzisa imithi, kufanele kuqhathaniswe ingozi yokusebenzisa imithi nezinzuzo ezizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo olukhulu noma oluhambelana nokwaleka kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokwaleka, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubudlelwano bobudala nemiphumela ka-regorafenib kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-regorafenib kubantu abadala. Ayikho izifundo ezanele kwabesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokusebenzisa le mithi ngesikhathi sokuncelisa. Nakuba ezinye izimithi kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlaliswe ngezansi. Ukuhlangana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile akusikholisiwe, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ezinye izimithi akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla ngoba ukuhlangana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba nezinye izimithi kungase futhi kubangele ukuhlangana. Ukuhlangana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile akusikholisiwe, kodwa kungase kungakhuphuki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi esetshenziswa ekwelapheni umdlavuza inamandla kakhulu futhi ingaba nemiphumela eminingi emibi. Ngaphambi kokusebenzisa le mithi, qiniseka ukuthi uyayiqonda yonke imingcele nezinzuzo. Kubalulekile ukuthi usebenzisane eduze nodokotela wakho phakathi nokwelashwa kwakho. Thatha le mithi kuphela njengoba uqondiswe udokotela wakho. Ungayithathi ngaphezulu, ungayithathi kaningi, futhi ungayithathi isikhathi eside kunalokho oqondiswe udokotela wakho. Ukwenza kanjalo kungandisa amathuba emiphumela emibi. Le mithi iza ne-insert yolwazi lwabaguli. Kubalulekile kakhulu ukuthi ufunde futhi uqonde lolu lwazi. Qiniseka ukuthi ubuza udokotela wakho nganoma yini ongayiqondi. Gwinya ithebulethi yonke ngamanzi. Ungayicwili, ungayaphula, noma ungayikhinya. Thatha le mithi ngesikhathi esifanayo nsuku zonke ngokudla okunefutha eliphansi (okunefutha elingaphansi kuka-30%). Ungadli i-grapefruit noma uphuze ijusi le-grapefruit ngenkathi usebenzisa le mithi. Imikhiqizo ye-grapefruit ingandisa inani lemithi emzimbeni wakho. Inani lemithi le mithi lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi ale mithi. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukwenza kanjalo. Inani lemithi olithathayo lixhomeke emandleni emithi. Futhi, inani lezingxenye olithathayo nsuku zonke, isikhathi esivunyelwe phakathi kwezingxenye, nobude besikhathi olithatha khona imithi kuncike enkingeni yezokwelapha oyisebenzisela imithi. Uma uphuthelwa yingxenye yale mithi, yithatha ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi sokuthatha ingxenye yakho elandelayo, susa ingxenye ephuthelwe futhi ubuyele esikhathini sakho sokuthatha imithi. Ungawandisi amanani. Gcina imithi esitsheni esivaliwe ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungayivumeli ukuba iqhwaze. Gcina ingafinyeleleki kubantwana. Ungagcini imithi esephelile noma imithi engasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele uyilahla kanjani noma iyiphi imithi ongayisebenzisi. Gcina imithi esitsheni sayo sokuqala. Ungayihlanganisi amathebulethi emakhasini okuthatha amaphilisi nsuku zonke noma masonto onke. Lahla noma yimaphi amathebulethi angasetshenzisiwe emavikini angu-7 ngemuva kokuvula ibhodlela okokuqala.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.