Sacubitril nevalsartan (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Entresto, Entresto Ikhukhulayo
Mayelana naleli khambi
Ukuhlanganiswa kweSacubitril nevalsartan kusetshenziswa ekwelapheni ukwehluleka kwenhliziyo okungapheliyo kubantu abadala ukuze kusizwe ekunciphiseni ingozi yokufa nokungeniswa esibhedlela. Lolu lwelapha futhi lusetshenziswa ekwelapheni abantwana abanehluleko lenhliziyo elinawo imizimba. I-Valsartan iyilokhu okuvimba amandla e-angiotensin II (ARB). Isebenza ngokuvimba into emzimbeni ebangela ukuba imithambo yegazi iqiniseke. Ngenxa yalokho, i-valsartan ikhulula imithambo yegazi. Lokhu kunciphisa ukucindezeleka kwegazi futhi kwandise ukunikezwa kwegazi no-oksijini enhliziyweni. Lolu lwelapha lutholakala kuphela ngomyalo wezokwelapha. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqululo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqakathekile noma oluhambisana nokwaleka kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unanoma yiluphi olunye uhlobo lwezinto ozaleka kuzo, njengokudla, izibenge, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantwana ezingalimi ukusetshenziswa kokudibeneyo kwe-sacubitril ne-valsartan kubantwana abaneminyaka engu-1 nangaphezulu. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalimi ukusetshenziswa kokudibeneyo kwe-sacubitril ne-valsartan kubantu abadala. Izifundo kwabesifazane abancelisa zibonise imiphumela emibi kubantwana. Kufanele kuqokwe enye imithi noma ukhuluke ukuncelisa ngenkathi usebenzisa le mithi. Nakuba ezinye izimithi kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukusebenzisana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwawo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayikhuthazwa. Udokotela wakho anganquma ukungakwelaphi ngale mithi noma ashintshe ezinye izimithi ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile akusikhuthazwa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi iqokiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma kokubili imithi. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo kungabangela ukwanda kengozi yezinye izingozi ezibekiwe, kodwa ukusebenzisa kokubili imithi kungaba ukwelashwa okuhle kuwe. Uma kokubili imithi iqokiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma kokubili imithi. Ezinye izimithi akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla ngoba kungenzeka kube khona ukusebenzisana. Ukusebenzisa utshwala noma utshaba nanoma iyiphi imithi kungabangela ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha leli leyeza ngokuqondile njengoba kunqunyiwe udokotela wakho. Ungalithathi ngokweqile, ungalithathi njalo, futhi ungalithathi isikhathi eside kunalokho okunqunyiwe udokotela wakho. Ukwenza kanjalo kungandisa amathuba ezingozi ezihambisana naleli leyeza. Leli leyeza liza nephepha lemininingwane yomguli nemiyalo yomguli. Funda futhi ulandele imiyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Ngabantwana abangakwazi ukugwinya amathebulethi, umthengisi wezidakamizwa uzoxuba leli leyeza njengokuxuba okungumfutho. Shaya ibhodlela lokuxuba kahle ngaphambi kokusebenzisa. Ukusebenzisa ama-Entresto® Sprinkle oral pellets: Tshela udokotela wakho uma uke waba nanoma iyiphi impendulo engaqondakali noma ehambisana nokwaleka kwaleli leyeza noma amanye amayeza. Tshela odokotela wakho uma unanoma yiluphi olunye uhlobo lwezinto ozaleka kuzo, njengokudla, izibhebhe, izinto ezigcinayo, noma izilwane. Ngamathuluzi angaphandle komthetho, funda ilebula noma izithako zephakheji ngokucophelela. Uma uphuthelwa yidosi yaleli leyeza, yithathe ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi sedosi yakho elandelayo, susa le dosi ophuthelwe yiyo bese ubuyela esimweni sakho sokuthatha imithi. Ungawandisi ama-doses. Gcina kude nabantwana. Ungagcini imithi esele iphelile noma imithi ongekho isidingo sayo. Buza ochwepheshe bakho bezempilo ukuthi kufanele uyilahla kanjani noma iyiphi imithi ongayisebenzisi. Gcina imithi embizeni evaliwe ekamelweni lokushisa, kude nokushisa, ukufuma, nokukhanya okuqondile. Gcina ungayifrizi. Ungagcina ukuxuba okungumfutho ekamelweni lokushisa kuze kube izinsuku ezingama-15. Ungayifaki esihlalweni esibandayo.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.