Safinamide (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Xadago
Mayelana naleli khambi
ISafinamidi isetyenziswa ndawonye nelevodopa necarbidopa ukuze ikwelaphe abantu abadala abane-Parkinson's disease abanamazinga 'off'. Lolu luhlobo lolwemi lusebenza njengesiqalekelo se-MAO-B esenza ukuba kube lula ukwandisa nokukhulisa imiphumela ye-levodopa futhi kungasiza ekuqedeni ukwanda kwe-Parkinson's disease. Lolu lwemi luyatholakala kuphela ngomyalelo wezokwelapha. Lo mkhiqizo uyatholakala ngezindlela zokwelapha ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucineni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqululo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma iyiphi impendulo engavamile noma ebangelwa uketshezi kule mithi noma kunoma iyiphi eminye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unanoma iyiphi enye into yoketshezi, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenamithi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubudlelwano bobudala nemiphumela yesafinamide kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingakhawulela ukusetshenziswa kwesafinamide kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izimithi kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubaluleke kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayikhuthazwa. Udokotela wakho angase anqume ukungakwelaphi ngale mithi noma ashintshe ezinye izimithi ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayikhuthazwa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo kungabangela ukwanda kengozi yezinye izingozi ezibekiwe, kodwa ukusebenzisa kokubili imithi kungaba ukwelashwa okuhle kuwe. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ezinye izimithi akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba nezinye izimithi kungabangela ukuhlangana. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile ayikhuthazwa, kodwa kungase kungenzeki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unanoma iyiphi enye inkinga yezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha leli leyeza njengoba nje uqondiswe yidoctor yakho. Ungalithathi ngaphezulu, ungalithathi kaningi, futhi ungalithathi isikhathi eside kunalokho udokotela wakho akuqondisile. Leli leyeza kufanele libe nepheshana lolwazi lwabaguli. Funda bese ulandela imiyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Gwinya ithebulethi yonke. Ungayicwili, ungayiqhekeza, noma ungayikhononde. Ungalithatha leli leyeza ngokudla noma ngaphandle kokudla. Thatha leli leyeza ngesikhathi esifanayo nsuku zonke. Inani leli leyeza lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esembele. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi aleli leyeza. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani leyeza olithathayo lixhomeke emandleni leyeza. Futhi, inani lezinani olithathayo nsuku zonke, isikhathi esivunyelwe phakathi kwezinani, nobude besikhathi olithatha leyeza kuya ngenkinga yezokwelapha oyisebenzisela leyeza. Uma uphuthelwa yisilinganiso saleli leyeza, susa isilinganiso esiphuthelwe bese ubuyela esimweni sakho sokuthola isilinganiso. Ungawandisi ama-doses. Uma uphuthelwe yisilinganiso, thatha isilinganiso esilandelayo ngesikhathi esifanayo ngosuku olulandelayo. Gcina leyeza esitsheni esivaliwe ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungawagandisi. Gcina ungafinyeleleki kubantwana. Ungagcini leyeza eliphelile noma leyeza elingasasetshenziswa. Buza ochwepheshe bakho bezempilo ukuthi kufanele ulahle kanjani noma yiliphi leyeza ongeke ulisetshenzise.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.