Tacrolimus (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Astagraf XL, Envarsus XR, Hecoria, Prograf
Mayelana naleli khambi
ITacrolimus isetshenziswa kanye nezinye izidakamizwa ukuvimbela umzimba ekulahlekweni komthamo oshintshiwe (isib. ikidini, isibindi, inhliziyo, noma amaphaphu). Lolu lwemi isetshenziswa kanye ne steroids, azathioprine, basiliximab, noma mycophenolate mofetil. ITacrolimus iyingxenye yeqembu lemithi ebizwa ngokuthi yizidakamizwa zokucindezela amasosha omzimba. Uma isiguli samukela ukuhlinzwa komthamo, amangqamuzana amhlophe egazi azozama ukususa (ukulahla) umthamo oshintshiwe. ITacrolimus isebenza ngokucindezela amasosha omzimba ukuvimbela amangqamuzana amhlophe egazi ekuzameni ukususa umthamo oshintshiwe. ITacrolimus iyilwemi elinamandla kakhulu. Lingabangela imiphumela emibi engaba nzima kakhulu, njengobunzima bezingqinamba. Lingase liphinde liqede amandla omzimba okulwa nokutheleleka. Wena nodokotela wakho kufanele nixoxe ngezinzuzo zalolu lwemi kanye nezingozi zokulisebenzisa. Lolu lwemi lutholakala kuphela ngomyalo wodokotela. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqulu ozothatha wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqakathekile noma oluhambisana nokwaleka kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unanoma yiluphi olunye uhlobo lwezifo ezingalawuleki, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenamthetho, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zezingane ezizobeka umkhawulo ekusebenziseni i-Astagraf XL®ezinganeni ezineminyaka engu-4 nangaphezulu. Ukuphepha kanye nokusebenza kahle kuye kwaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zezingane ezizobeka umkhawulo ekusebenziseni i-Prograf®ezinganeni ezithole ukuhlinzwa ezinso, isisu, inhliziyo, noma amaphaphu. Ukuphepha kanye nokusebenza kahle kuye kwaqiniswa. Azikho izifundo ezifanele ezenziwe ngokuphathelene nobudlelwano bobudala nemiphumela ye-Envarsus XR®kubantu abancane. Ukuphepha kanye nokusebenza kahle akukaqiniswanga. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezizobeka umkhawulo ekusebenziseni i-tacrolimus kubantu abadala. Noma kunjalo, abantu abadala banesikhathi esiningi sokuhlupheka ngezinkinga zezinso, isibindi, noma inhliziyo, okungase kudinge ukunakekelwa nokulungiswa komthamo kubantu abamukela i-tacrolimus. Ayikho izifundo ezifanele kwabesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingase zidingeke. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlu lwezinto ezingezansi. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into ehlanganisiwe. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayinconywa. Udokotela wakho angase anqume ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayinconywa, kodwa kungase kudingeke kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyisebenzisa kangakanani enye noma kokubili imithi. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo kungabangela ukwanda kengozi yezinye izingozi ezibekiwe, kodwa ukusebenzisa kokubili izidakamizwa kungaba ukwelashwa okuhle kuwe. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyisebenzisa kangakanani enye noma kokubili imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba ngezidakamizwa ezithile kungabangela ukusebenzisana okwenzeka. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into ehlanganisiwe. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile ayinconywa, kodwa kungase kungakhuphuki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha leli lemithi njengoba nje udokotela wakho ekuqondisa. Ungathathi okuningi noma okuncane kwalokho futhi ungathathi njalo kunalokho udokotela wakho akuqondisile. Ukusebenzisa okuningi kuzokwandisa amathuba ezingozi ezihambisana nale mithi, kuyilapho ukusebenzisa okuncane kungabangela ukuphikisa komzimba wakho esitho ositholile. Le mithi iza neNcwadi Yemithi noma iphepha lemininingwane yomguli nemiyalo yomguli. Funda futhi ulandele imiyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Le mithi ihlale isebenziswa kanye neminye imithi. Qiniseka ukuthi uyayiqonda indlela yokuthatha yonke imithi yakho ngosuku. Udokotela wakho uzakukunika uhlelo lwansuku zonke lokusebenzisa imithi yakho. Ungathatha ikhaphsul ekhulula ngokushesha noma isiliqudi ngomlomo ngokudla noma ngaphandle kokudla. Kodwa uthathe ngendlela efanayo njalo. Uma usebenzisa ikhaphsul ekhulula kancane: Uma usebenzisa ithebulethi ekhulula kancane: Uma usebenzisa i-granule yokuxuba ngomlomo, ungayithatha ngokudla noma ngaphandle kokudla, kodwa kufanele uyithathe ngendlela efanayo njalo. Ukuhlanganisa isiliqudi ngomlomo: Akufanele udle i-grapefruit noma uphuze ijusi le-grapefruit ngesikhathi usebenzisa le mithi. I-grapefruit nejusi le-grapefruit zizokwandisa inani lemithi emzimbeni. Ungayeki ukusebenzisa le mithi ngaphandle kokubheka kuqala nodokotela wakho. Kungase kudingeke ukuthi uthathe le mithi impilo yakho yonke ukuvimbela umzimba wakho ekuphikiseni ukutholakala kwesitho. Sebenzisa kuphela uhlobo lale mithi udokotela wakho akuqondisile. Ama-brand ahlukene angase angasebenzi ngendlela efanayo. Ungasebenzisi i-Prograf® kanye ne-cyclosporine. I-Tacrolimus noma i-cyclosporine kufanele iyeke okungenani amahora angu-24 ngaphambi kokuqala okunye. Inani lemithi leli lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi ale mithi. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lemithi oyithatha lixhomeke emandleni emithi. Futhi, inani lemithi oyithatha nsuku zonke, isikhathi esivunyelwe phakathi kwemithi, nobude besikhathi othatha imithi kuya ngesimo sezempilo oseyisebenzisela imithi. Uma uphuthelwa yidosi ye-Astagraf XL® futhi kungaphansi kwamahora angu-14 kusukela esikhathini esivamile, thatha idosi ophuthelwe yona ngokushesha. Uma sekudlule amahora angu-14 kusukela esikhathini esivamile, suka idosi ophuthelwe yona bese ubuyela esimisweni sakho esivamile. Uma uphuthelwa yidosi ye-Envarsus XR® futhi kungaphansi kwamahora angu-15 kusukela esikhathini esivamile, thatha idosi ophuthelwe yona ngokushesha. Uma sekudlule amahora angu-15 kusukela esikhathini esivamile, suka idosi ophuthelwe yona bese ubuyela esimisweni sakho esivamile. Gcina imithi esitsheni esivalekile ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okuqondile. Gcina ungayivumeli ukuba iqhube. Gcina ingafinyeleleki kubantwana. Ungagcini imithi esele iphelile noma imithi engasasetshenziswa. Buza ochwepheshe bakho bezempilo ukuthi kufanele uyilahla kanjani noma iyiphi imithi ongase uyisebenzise.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.