Yini i-Tacrolimus (Topical): Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Tacrolimus topical iyimithi kadokotela oyigcoba ngqo esikhumbeni sakho ukwelapha izimo ezithile zesikhumba ezivuvukalayo. Kuyisilungisi esinamandla sesimiso somzimba sokuzivikela esisiza ukuthulisa izimpendulo zomzimba zokuzivikela ezisebenza ngokweqile ezibangela ukucasuka kwesikhumba nokuvuvukala.

Le mithi ingeyeqembu lemithi ebizwa ngokuthi ama-topical calcineurin inhibitors. Cabanga ngayo njengokwelashwa okuqondiwe okusebenza ngqo lapho uyigcoba khona, kunokuthinta wonke umzimba wakho njengoba imithi yomlomo ingase yenze.

Yini i-Tacrolimus Topical?

I-Tacrolimus topical iyimithi ecindezela amasosha omzimba eza ngesimo samafutha owagcobayo ezindaweni zesikhumba ezithintekile. Ekuqaleni yathuthukiswa evela kumxube otholakala emabhaktheriya enhlabathi futhi isisize abantu ukuthi balawule izimo zesikhumba ezinzima kusukela ekuqaleni kweminyaka yama-2000.

Le mithi isebenza ngokucindezela amaseli athile ohlelo lomzimba lokuzivikela esikhumbeni sakho okufaka isandla ekuvuvukeni nasekucasukeni. Isebenza ikakhulukazi ezimweni lapho amasosha omzimba akho ehlasela ngamaphutha amaseli esikhumba anempilo.

Uzothola i-tacrolimus topical itholakala ngamandla amabili: 0.03% kanye no-0.1%. Udokotela wakho uzoqaphela ukuthi yiliphi iqina elifanele isimo sakho esithile nokuzwela kwesikhumba.

Isetshenziselwani i-Tacrolimus Topical?

I-Tacrolimus topical ikakhulukazi inikezwa ukwelapha i-atopic dermatitis ephakathi nendawo kuya kokubi kakhulu, eyaziwa nangokuthi i-eczema. Lesi simo sesikhumba esingamahlalakhona sibangela izindawo ezibomvu, ezilumayo, nezivuvukele ezingathinta kakhulu induduzo yakho yansuku zonke nekhwalithi yempilo.

Udokotela wakho angase futhi ayinikeze ezinye izimo zesikhumba ezivuvukalayo lapho ukwelashwa kwendabuko kungazange kunikeze ukukhululeka okwanele. Ezinye izazi zesikhumba ziyisebenzisa ngaphandle kwelebula ezimweni ezinjenge-vitiligo, i-psoriasis ezindaweni ezizwelayo, noma i-allergic contact dermatitis.

Umuthi ubaluleke kakhulu ekwelapheni i-eczema ezindaweni ezibucayi njengobuso bakho, intamo, kanye nemifantu yesikhumba lapho okokugcoba okunamandla kwe-steroid kungase kubangele imiphumela engathandeki uma kusetshenziswa isikhathi eside.

Isebenza Kanjani I-Tacrolimus Topical?

I-Tacrolimus topical isebenza ngokuvimba ama-enzyme athile abizwa ngokuthi i-calcineurin kumaseli akho omzimba. Uma lawa ma-enzyme evinjelwe, amaseli akho omzimba awasakwazi ukukhiqiza amakhemikhali avuvukalisayo abangela ububomvu, ukuvuvukala, nokuluma.

Lokhu kwenza i-tacrolimus ibe umuthi onamandla aphakathi nendawo onamandla kakhulu kune-steroid topical emnene kodwa ngokuvamile imnene kune-steroid creams enamandla amakhulu. Inikeza usizo oluqondiwe ngaphandle kweminye yemiphumela yokunciphisa isikhumba ehambisana nokusetshenziswa kwe-steroid isikhathi eside.

Umithi ngokuvamile uqala ukusebenza phakathi nezinsuku ezimbalwa kuya evikini lokusetshenziswa njalo. Kodwa-ke, kungase kuthathe amasonto amaningana ukubona izinzuzo eziphelele, ngakho ukubekezela kubalulekile ngesikhathi sokwelashwa kwakho.

Kufanele Ngiyithathe Kanjani I-Tacrolimus Topical?

Sebenzisa i-tacrolimus topical ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile kabili ngosuku esikhumbeni esihlanzekile, esomile. Qala ngokuwasha izandla zakho kahle, bese uhlanza indawo ethintekile ngobumnene bese uyomisa ngaphambi kokusebenzisa ungqimba oluncane lwe-ointment.

Akudingeki ukuthi udle noma yini ekhethekile ngaphambi kokusebenzisa lo muthi ngoba usetshenziswa ngaphandle. Kodwa-ke, gwema ukuwusebenzisa ngokushesha ngemva kokugeza noma ukubhukuda lapho isikhumba sakho simanzi kakhulu, njengoba lokhu kungakhuphula ukumuncwa futhi kungase kubangele ukucasuka.

Gcoba i-ointment ngobumnene esikhumbeni sakho size simuncwe, kodwa ungayihlikihli ngamandla. Ngemva kokusebenzisa, phinda ugeze izandla zakho ngaphandle uma welapha izandla zakho ngqo.

Gwema ukumboza indawo elashwayo ngamabhandeshi aqinile noma ukugqoka okuvalayo ngaphandle uma udokotela wakho ekuyala ngqo ukuba wenze njalo. Isikhumba sakho sidinga ukuphefumula ngenkathi umuthi usebenza.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Tacrolimus Topical?

Isikhathi sokwelashwa nge-tacrolimus topical siyahluka kakhulu kuye ngesimo sakho esithile nokuthi usabela kanjani emuthini. Abanye abantu bawusebenzisa amasonto ambalwa ngesikhathi sokuqubuka, kanti abanye bangase badinge ukwelashwa isikhathi eside.

Ukuqubuka kwe-eczema okukhulu, ungase ukusebenzise nsuku zonke amasonto angu-2-4 kuze kube yilapho isikhumba sakho sicacile, bese ushintshela ekusetshenzisweni okungavamile ukuze kulondolozwe. Udokotela wakho uzokwenza uhlelo lokwelashwa olwenzelwe wena ngokusekelwe ekuphenduleni kwesikhumba sakho.

Abantu abaningi bathola ukuthi banganciphisa kancane kancane ukuthi bawusebenzisa kangaki umuthi njengoba isikhumba sabo sithuthuka. Lokhu kungasho ukusuka ekusebenziseni kabili ngosuku kuya kanye ngosuku, bese kuya ngosuku olulodwa, futhi ekugcineni ukusetshenziswa njengoba kudingeka.

Ungayeki ukusebenzisa i-tacrolimus topical ngokuzumayo ngaphandle kokubonisana nodokotela wakho, ikakhulukazi uma ubuyisebenzisa njalo. Udokotela wakho uzokuqondisa ukuthi ungawunciphisa kanjani ngokuphepha umuthi ukuze uvimbele ukuqubuka kabusha.

Yiziphi Imiphumela Eceleni ye-Tacrolimus Topical?

Abantu abaningi bayakwazi ukubekezelela i-tacrolimus topical kahle, kodwa njengayo yonke imithi, ingabangela imiphumela emibi. Izindaba ezinhle ukuthi imiphumela emibi engathí sina ayivamile uma isetshenziswa ngaphandle.

Nansi imiphumela emibi evame kakhulu ongase uyithole, ikakhulukazi ezinsukwini ezimbalwa zokuqala zokwelashwa:

• Umuzwa wokusha noma wokugwaza endaweni yokusebenzisa
• Ukubomvu kwesikhumba noma ukufudumala
• Ukuqina (okungase kube kubi okwesikhashana ngaphambi kokuthuthuka)
• Ukuzwa ukuluma noma ukuba ndikindiki kwesikhumba
• Ukwanda kokuzwela ekushiseni noma ebandayo
• Ucasuko oluncane lwesikhumba noma ukuqubuka

Le miphumela emibi ejwayelekile ngokuvamile iyathuthuka njengoba isikhumba sakho sizivumela emuthini, ngokuvamile ngesonto lokuqala lokwelashwa.

Imiphumela emibi engavamile kodwa ekhathazayo edinga ukuxhumana nodokotela wakho ihlanganisa:

• Izimpawu zokutheleleka kwesikhumba (ukubomvu okukhulu, ukufudumala, amanyela, noma imigqa ebomvu)
• Ukusha okukhulu okungathuthuki ngemva kwezinsuku ezimbalwa
• Ushintsho olungavamile esikhumbeni noma ukukhula
• Amanodi e-lymph aqhubukile
• Izimpawu ezinjengomkhuhlane
• Umkhuhlane oqhubekayo

Nakuba kungavamile kakhulu, abanye abantu bangase babe nokusabela komzimba noma bathuthukise ukuzwela okukhulu ekuthelelekeni kwesikhumba. Uma uqaphela noma yiziphi izinguquko ezingavamile esikhumbeni noma uzizwa ungaphilile ngenkathi usebenzisa i-tacrolimus, xhumana nomhlinzeki wakho wezempilo.

Ubani Ongafanele Athathe i-Tacrolimus Topical?

I-Tacrolimus topical ayifanele wonke umuntu, futhi izimo ezithile noma izimo zingase zikwenze kungafaneleki esimweni sakho. Udokotela wakho uzoqapha ngokucophelela ukuthi lo muthi ukufanele yini.

Akufanele usebenzise i-tacrolimus topical uma wazi ukuthi unokungezwani komzimba ne-tacrolimus noma yiziphi izithako ezikugcoba. Abantu abanezimo ezithile zofuzo ezithinta amasosha abo omzimba bangase badinge nokugwema lo muthi.

Nakhu okubalulekile okungase kuthinte ukuthi i-tacrolimus topical ikufanele yini:

• Ukutheleleka kwesikhumba okusebenzayo (amagciwane, amagciwane, noma isikhunta)
• Ukuvikeleka komzimba okungahambisani kahle ngenxa yesifo noma imithi
• Ukukhulelwa noma ukuncelisa (xoxa ngokucophelela nodokotela wakho)
• Izingane ezingaphansi kweminyaka emi-2 ubudala (akuvamile ukunconywa)
• Umlando we-lymphoma noma eminye iminyango
• Isifo esibi sezinso

Uma uthatha eminye imithi ecindezela amasosha omzimba, udokotela wakho uzodinga ukucabangela ngokucophelela imiphumela ehlanganisiwe emzimbeni wakho ngaphambi kokunquma i-tacrolimus topical.

Amagama Omkhiqizo we-Tacrolimus Topical

I-Tacrolimus topical itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Protopic iyona eyaziwa kakhulu. Le nguqulo yegama lomkhiqizo iqukethe isithako esifanayo esisebenzayo njenge-tacrolimus ointment ejwayelekile.

Amanye amagama ebhrendi angase atholakale ngokuya ngendawo yakho nekhemisi. Umkhemisi wakho angakusiza ukuthi uqonde ukuthi ngabe uthola igama lebhrendi noma inguqulo ejwayelekile yomuthi.

Zombili izinhlobo zamagama ebhrendi kanye nezijwayelekile ze-tacrolimus topical zisebenza ngendlela efanayo. Ukukhetha kuvame ukuncika ekuhlinzekweni komshwalense, ukucatshangelwa kwezindleko, kanye nokukhetha komuntu siqu.

Ezinye izindlela ze-Tacrolimus Topical

Uma i-tacrolimus topical ingasebenzi kahle kuwe noma idala imiphumela engathandeki, kukhona ezinye izindlela zokwelapha ezitholakalayo zokuphatha izimo zesikhumba ezivuthayo.

Ezinye izithiyo ze-topical calcineurin zifaka i-pimecrolimus (Elidel), esebenza ngendlela efanayo ne-tacrolimus kodwa ingaba mnene kubantu abathile. Udokotela wakho angase akuncome ukuthi uzame lokhu uma i-tacrolimus idala ukucasuka okuningi.

Ama-corticosteroids e-Topical ahlala eyindlela yokwelapha eyinhloko ye-eczema nezinye izimo zesikhumba ezivuthayo. Lokhu kuza ngamandla ahlukahlukene kanye namafomula, kusuka ku-hydrocortisone emnene kuya kuma-steroid kadokotela anamandla.

Izinketho zokwelapha ezintsha zifaka izithiyo ze-topical PDE4 njenge-crisaborole (Eucrisa) kanye nezithiyo ze-JAK ezifana ne-ruxolitinib (Opzelura). Le mithi isebenza ngezindlela ezahlukene ukunciphisa ukuvuvukala kwesikhumba.

Ingabe i-Tacrolimus Topical Ingcono Kune-Hydrocortisone?

I-Tacrolimus topical ne-hydrocortisone zisebenza ngendlela ehlukile futhi zinezinzuzo ezihlukile ngokuya ngesimo sakho esithile. Akukho noyedwa othi ngokujwayelekile "ungcono" kunomunye, kodwa ngamunye unamandla athile.

I-Tacrolimus topical ngokuvamile isebenza kahle kakhulu ku-eczema ephakathi nendawo kuya kokukhulu futhi ayibangeli ukuncipha kwesikhumba njengoba ukusetshenziswa kwama-steroid isikhathi eside kungenza. Lokhu kuyenza ibaluleke ikakhulukazi ekwelapheni izindawo ezizwelayo njengobuso bakho nentamo.

I-Hydrocortisone, ngakolunye uhlangothi, ivame ukusebenza ngokushesha ekushayweni okukhulu futhi iyatholakala ngaphandle kokuthengwa ngaphandle kwemithi ngamandla aphansi. Futhi ngokuvamile ayibizi kakhulu futhi ingase idale ukucasuka okuncane ekuqaleni.

Udktela wakho uzocabangela izinto ezifana nobukhulu besimo sakho, indawo yesikhumba esithintekile, umlando wakho wokwelashwa, nezintandokazi zakho siqu lapho enquma ukuthi imuphi umuthi ofaneleka kakhulu kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Tacrolimus Topical

Ingabe i-Tacrolimus Topical iphephile ukusetshenziswa isikhathi eside?

I-Tacrolimus topical ngokuvamile ithathwa njengephephile ukusetshenziswa isikhathi eside uma isetshenziswa njengoba kuqondiswe udokotela wakho. Ngokungafani nama-steroid topical, ayibangeli ukuncipha kwesikhumba noma ezinye izinguquko zesakhiwo esikhumbeni sakho ngokusebenzisa isikhathi eside.

Kodwa-ke, ngenxa yokuthi ithinta amasosha akho omzimba, udokotela wakho uzokuhlola njalo ngesikhathi sokwelashwa isikhathi eside. Bangase batusa ukuphumula ngezikhathi ezithile noma ukulungiswa kwemithamo ngokuya ngokuthi isikhumba sakho siphendula kanjani.

Okubalulekile ukuyisebenzisa ngendlela efanele ngaphansi kokuqondisa kwezokwelapha kunokuyisebenzisa ngokuqhubekayo ngaphandle kokuqondiswa. Udokotela wakho uzokusiza ukuthi uthole ukulinganisela okulungile phakathi kokwelashwa okuphumelelayo nokuphepha.

Ngingenzani uma ngisebenzisa i-Tacrolimus Topical eningi ngengozi?

Uma ngengozi usebenzisa i-tacrolimus topical eningi, ungangeni ekuqhumeni. Sula ngobumnene okweqile ngendwangu ehlanzekile noma ithishu, kodwa ungascrub noma ucacise isikhumba sakho.

Ukusetshenziswa okuningi ngezikhathi ezithile akunakwenzeka ukuthi kubangele izinkinga ezinkulu, kodwa kungase kwandise ingozi yakho yokucasuka kwesikhumba noma ukusha. Uma uhlangabezana nokungakhululeki okukhulu, ungafaka ngobumnene indawo ngamanzi abandayo.

Xhumana nodokotela wakho uma usebenzisa njalo imithi eningi kakhulu noma uma uhlangabezana nezimpawu ezingavamile ngemva kokusebenzisa ngokweqile. Bangakwazi ukulungisa uhlelo lwakho lokwelashwa ukuze bavimbele izinkinga zesikhathi esizayo.

Ngingenzani uma ngiphuthelwa umthamo we-Tacrolimus Topical?

Uma uphuthelwa umthamo we-tacrolimus topical, uyisebenzise ngokushesha lapho ukhumbula, ngaphandle uma sekuyisikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho evamile.

Ungasebenzisi imithi eyengeziwe ukuze ubuyisele umthamo ongawutholanga, ngoba lokhu kungakhuphula ingozi yokucasuka kwesikhumba sakho. Ukungaguquguquki kubalulekile, kodwa imithamo engatholakali ngezikhathi ezithile ngeke ibe nomthelela omkhulu ekwelashweni kwakho.

Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi ocingweni lwakho noma ukuxhumanisa izikhathi zokusebenzisa emisebenzini yansuku zonke efana nokuxubha amazinyo akho.

Ngingayeka nini ukuthatha i-Tacrolimus Topical?

Ngokuvamile ungaqeda ukusebenzisa i-tacrolimus topical lapho isimo sesikhumba sakho sesilule futhi siqhubeka sizinzile isikhathi esinconywe udokotela wakho. Lokhu ngokuvamile kuhilela ukunciphisa kancane kancane kunokuyeka kungazelelwe.

Udokotela wakho uzokuqondisa ngohlelo lokunciphisa olungase luhlanganise ukunciphisa imvamisa yokusebenzisa emasontweni amaningana. Lokhu kusiza ekuvimbeleni ukuqubuka okubuyayo ngenkathi kugcinwa ukuthuthuka okufinyelelwe.

Abanye abantu bangase badinge ukuqhubeka nokusebenzisa i-tacrolimus topical ngezikhathi ezithile ukuze banakekele, ikakhulukazi uma benemibandela engapheli njenge-atopic dermatitis. Udokotela wakho uzosebenza nawe ukuthola uhlelo oluncane olusebenzayo.

Ngingayisebenzisa i-Tacrolimus Topical neminye imikhiqizo yokunakekela isikhumba?

Ngokuvamile ungasebenzisa i-tacrolimus topical neminye imikhiqizo yokunakekela isikhumba, kodwa isikhathi nokukhethwa komkhiqizo kubalulekile. Sebenzisa i-tacrolimus esikhumbeni esihlanzekile, esomile, bese ulinda okungenani imizuzu engama-30 ngaphambi kokusebenzisa eminye imikhiqizo.

Ama-moisturizers athambile, angenaphunga ngokuvamile alungile ukuthi asetshenziswe futhi angase asize ngempela ukunciphisa ukucasuka okuvela ku-tacrolimus. Kodwa-ke, gwema imikhiqizo equkethe utshwala, ama-asidi, noma ezinye izithako ezingase zicasule.

Njalo hlola nodokotela wakho noma usokhemisi ngaphambi kokuhlanganisa i-tacrolimus neminye imikhiqizo yokunakekela isikhumba enezidakamizwa, njengoba ezinye izinhlanganisela zingase zikhuphule ukucasuka noma zithinte ukumuncwa.