Taliglucerase alfa (indlela ye-intravenous)
Imikhiqizo etholakalayo
Elelyso
Mayelana naleli khambi
Isicathulo se-Taliglucerase alfa sisetshenziswa ekwelapheni isikhathi eside sesifo seGaucher sohlobo 1. Lesi sifo sibangelwa ukungabikho kwesinye i-enzyme emzimbeni ebizwa nge-glucocerebrosidase. Le-enzyme iyadingeka ukuze umzimba usebenzise amafutha ngendlela efanele, futhi amafutha azoqongelela ezindaweni ezithile zomzimba uma i-enzyme ingabikho. I-Taliglucerase alfa ithatha indawo ye-enzyme efile ukuze isize umzimba ekuqondiseni amafutha. Lolu lwemi lusetshenziswa kuphela ngudokotela noma ngaphansi kokunakekelwa kwakhe okuqondile. Lo mkhiqizo uyatholakala ngezindlela zokulinganisela ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucatshangeni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqulu ozothatha wena nodokotela wakho. Kulo muthi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma iyiphi impendulo engavamile noma ebangelwa uketshezi kulo muthi noma kunoma iyiphi eminye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zoketshezi, njengokudla, izibenge, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela yokubeka i-taliglucerase alfa kubantwana abaneminyaka engaphansi kwengu-4. Ukuphepha nokuphumelela akukaqiniswa. Nakuba izifundo ezifanele ezihlobene nobudala nemiphumela yokubeka i-taliglucerase alfa azikwenzelwanga kubantu abadala, azikho izinkinga ezithile zabantu abadala ezibhalwe kuze kube manje. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa lo muthi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha lo muthi ngesikhathi sokuncelisa. Nakuba ezinye izimithi akufanele zisetshenziswe ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungadingeka. Tshela ochwepheshe bakho bezempilo uma uthatha noma iyiphi enye imithi yokuqaphela noma engekho iresiphi (over-the-counter [OTC]). Ezinye izimithi akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba ngezinye izimithi kungabangela ukuhlangana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba.
Indlela yokusebenzisa leli khambi
Umshula wesibeletho noma omunye ochwepheshe bezempilo oqeqeshwe uzohlinzeka wena noma ingane yakho leli lethu esibhedlela noma ekliniki. Leli lethu linikezwa nge-IV catheter ebekwe kwenye yezinsimbi zakho. Kumele kuqanjwe kancane, ngakho-ke i-IV yakho izohlala isikhathi esingamaminithi angu-60 kuya kwangu-120. Ngokuvamile linikezwa masonto onke. Udokotela wakho angakunika amanye amayethu ngaphambi kokwelashwa (isib. imithi yokwelapha ukungezwani, i-steroid) ukusiza ukuvimbela imiphumela engathandeki.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.