Talquetamab-tgvs (indlela yokugcoba ngaphansi kwesikhumba)
Imikhiqizo etholakalayo
Mayelana naleli khambi
Isitofu se-Talquetamab-tgvs sisetshenziswa ekwelapheni i-multiple myeloma ebuyile (umdlavuza obubuyile) noma engaphenduki (umdlavuza ongaphenduki ekwelapheni) kubantu abake bamukela okungenani ukwelashwa okungu-4 ngaphambili. Lokhu kwelashwa ngaphambili kuhlanganisa isithinteli se-proteasome, i-immunomodulatory agent, kanye ne-anti-CD38 monoclonal antibody. Lena imithi itholakala kuphela ngaphansi kohlelo lokusabalalisa oluqediwe oluthi Tecvayli™ ne-Talvey™ REMS (Uhlelo Lokuhlola Ubungozi Nokunciphisa). Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucatshangeni kokusebenzisa imithi, izingozi zokuthatha imithi kumele zilinganiswe nezinzuzo ezizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma iyiphi impendulo engaqondakali noma ebangelwa uketshezi kule mithi noma kwezinye izidakamizwa. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zoketshezi, njengokudla, izibenge, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela yokubeka i-talquetamab-tgvs kubantwana. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-talquetamab-tgvs injection kwabadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo izidakamizwa ezimbili ezahlukene zingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izindlela zokuphepha zingadingeka. Tshela ochwepheshe bakho bezempilo uma uthatha noma iyiphi enye imithi yokuqaphela noma engekho iresiphi (over-the-counter [OTC]). Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungabangela ukuhlangana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi ebizwa ngokuthi i-cancer inamandla kakhulu futhi ingaba nemiphumela eminingi emibi. Ngaphambi kokuthola le mithi, qiniseka ukuthi uyayiqonda yonke imingcipheko nezinzuzo. Kubalulekile ukuthi usebenzisane eduze nodokotela wakho phakathi nokwelashwa kwakho. Usizi noma omunye ochwepheshe bezempilo oqeqeshwe uzohlinzeka ngale mithi esikhungweni sezokwelapha. Le mithi inikezwa njengesiphuzo phansi kwesikhumba sakho, ngokuvamile esiswini noma emilenzeni. Kubalulekile kakhulu ukuthi uyiqonde imfuneko yohlelo lwe-Tecvayli™ ne-Talvey™ REMS, futhi uqonde incwajana yemithi ye-Tecvayli™ ne-Talvey™. Funda futhi ulandele lezi zinkomba ngokucophelela. Buza udokotela wakho uma unemibuzo. Buza u-pharmacist wakho ngencwajana yemithi uma ungenayo. Uzothola le mithi masonto onke noma njalo ngemva kwamasonto amabili (“isikimu sokuthuthukisa umthamo”).Isikimu sokuthola imithi masonto onke: Uzothola le mithi ngezinsuku 1 ne-4, kulandele umthamo wokuqala wokwelapha ngosuku 7. Ngemva kokuthola umthamo wakho wokuqala wokwelapha, le mithi ngokuvamile inikezwa kanye ngesonto.Isikimu sokuthola imithi njalo ngemva kwamasonto amabili: Uzothola le mithi ngezinsuku 1, 4, ne-7, kulandele umthamo wokuqala wokwelapha ngosuku 10. Ngemva kokuthola umthamo wakho wokuqala wokwelapha, le mithi ngokuvamile inikezwa njalo ngemva kwamasonto amabili. Udokotela wakho uzokucela ukuba uhlale amahora angu-48 ngemva kokuthola imithamo yokuqala. Ungase futhi uthole ezinye izidakamizwa (isib. imithi yokwelapha uketshezi, imithi yokwelapha ubushushu, i-steroid) amahora angu-1 kuya kwangu-3 ngaphambi kokuthola le mithi ukusiza ukuvimbela ukubonakala kwemiphumela emibi yokugonywa. Le mithi kufanele inikezwe ngesikimu esibekiwe. Uma uphuthelwe umthamo, shayela udokotela wakho, umhlinzeki wezempilo ekhaya, noma ikliniki yokwelashwa ukuze uthole imiyalo.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.