Yini i-Tasimelteon: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Tasimelteon iyimithi yokulala kadokotela esiza ukusetha kabusha umjikelezo wakho wemvelo wokulala nokuphaphamuka. Yenzelwe ngqo abantu abahlushwa izinhlobo ezithile zokuphazamiseka kokulala lapho iwashi labo langaphakathi lingahambisani nesigqi esivamile sosuku nobusuku.

Le mithi isebenza ngendlela ehlukile kunemithi yokusiza ukulala ejwayelekile. Esikhundleni sokukwenza ukozela nje, i-tasimelteon isebenza njengokukhuthaza okuncane kumgcini wesikhathi wemvelo wobuchopho bakho, okusiza ukubuyisela iphethini yokulala ejwayelekile ngokuhamba kwesikhathi.

Yini i-Tasimelteon Esetshenziselwa Yona?

I-Tasimelteon ngokuyinhloko inikezwa abantu abanezinkinga zokulala ezingama-Non-24-Hour Sleep-Wake Disorder, isimo esithinta ikakhulukazi abantu abangaboni nhlobo. Uma ungakwazi ukubona ukukhanya, umzimba wakho ulahlekelwa yisignali yawo eyinhloko yokwazi ukuthi liyini usuku noma ubusuku, okubangela ukuthi isimiso sakho sokulala sidlule ngemuva nsuku zonke.

Le mithi ngezinye izikhathi isetshenziselwa ezinye izinkinga ze-circadian rhythm lapho iwashi lakho langaphakathi lidinga ukusethwa kabusha. Udokotela wakho angase akucabangele uma unezinkinga eziqhubekayo zokuhlela ukulala ezingaphenduli kwezinye izindlela zokwelapha.

Imithi isiza ukuzinzisa iphethini yakho yokulala ukuze ukwazi ukulala futhi uvuke ngezikhathi eziqagelwayo. Lokhu kungathuthukisa kakhulu izinga lempilo yakho nokusebenza kwansuku zonke.

Isebenza Kanjani I-Tasimelteon?

I-Tasimelteon isebenza ngokulingisa i-melatonin, i-hormone ubuchopho bakho obukhiqiza ngokwemvelo ukubonisa ukozela. Iqondisa ama-receptors athile ebuchosheni bakho alawula i-circadian rhythm yakho, okuyiwashi lakho langaphakathi lama-24-hour lomzimba wakho.

Yicabange njengenkinobho yokusetha kabusha ngobumnene umjikelezo wakho wokulala. Imithi isiza ukuvumelanisa iwashi lakho langaphakathi nosuku lwangaphandle lwama-24-hour, kancane kancane iguqule isikhathi sakho sokulala sibuyele ephethini ejwayelekile.

Lokhu kuthathwa njengomuthi oqondiswe ngqo, okhethekile kunokuba kube usizo olujwayelekile lokulala. Yenzelwe ukubhekana nenkinga yesikhathi esiyisisekelo kunokumane kuqhubeke nokulala.

Kufanele Ngiyithathe Kanjani I-Tasimelteon?

Thatha i-tasimelteon njengoba nje udokotela wakho ekunqumele ngayo, ngokuvamile kanye ngosuku ngaphambi kokulala. Umthamo ojwayelekile uvame ukuba ngu-20 mg, othathwa ngesikhathi esifanayo ebusuku ngabunye ukusiza ukusungula umkhuba wokulala oqhubekayo.

Ungawuthatha lo muthi ngaphandle noma ngaphandle kokudla, kodwa zama ukuba qhubekayo ngokukhetha kwakho. Ukuwuthatha ngendlela efanayo ebusuku ngabunye kusiza umzimba wakho ukuba ube nokuphendula okulindelekile emuthini.

Isikhathi sibalulekile nge-tasimelteon. Yithathe ngesikhathi esifanayo njalo ebusuku, okungcono kakhulu uma ufuna ukusungula isikhathi sakho sokulala esivamile. Lokhu kuqhubeka kusiza ukuqinisa umjikelezo womzimba wakho wemvelo wokulala-ukuphaphamuka.

Gwema ukuthatha umuthi ngokudla okunamafutha amaningi, ngoba lokhu kungathinta ukuthi umzimba wakho uwumunca kahle kangakanani. Uma udla ngaphambi kokuwuthatha, khetha ukudla okulula ukuqinisekisa ukusebenza kahle.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Tasimelteon?

Abantu abaningi badinga ukuthatha i-tasimelteon amasonto amaningana kuya ezinyangeni ukuze babone ukuthuthuka okukhulu emikhubeni yabo yokulala. Udokotela wakho uzoqapha inqubekela phambili yakho futhi alungise ubude bokwelashwa ngokuya ngokuthi uphendula kahle kangakanani.

Ngokungafani neminye imithi yokulala eyenzelwe ukusetshenziswa kwesikhashana, i-tasimelteon ivame ukunqunywa isikhathi eside. Lokhu kungenxa yokuthi izifo ze-circadian rhythm ngokuvamile zidinga ukuphathwa okuqhubekayo kunokulungiswa okusheshayo.

Udokotela wakho uzobuyekeza njalo imikhuba yakho yokulala nokuphendula okuphelele ukuze anqume ukuthi kufanele uqhubeke yini nokwelashwa. Abanye abantu bangase badinge ukuyithatha unomphela, kanti abanye bangase bakwazi ukunciphisa imvamisa noma bayeke ngemva kokuba umjikelezo wabo wokulala uzinzile.

Yiziphi Imiphumela Eceleni Ye-Tasimelteon?

Abantu abaningi bayakwazi ukumelana ne-tasimelteon kahle, kodwa njenganoma imuphi umuthi, ingabangela imiphumela emibi. Izindaba ezinhle ukuthi imiphumela emibi engathi sína ayivamile ngalo muthi.

Nansi imiphumela emibi evame kakhulu ongase uyithole:

• Ikhanda
• Ukwanda komsebenzi wamaphupho noma amaphupho angajwayelekile
• Ukutheleleka kwepheshana eliphezulu lokuphefumula
• Ukutheleleka kwepheshana lomchamo

Le miphumela emibi ngokuvamile imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala okwelashwa.

Imiphumela emibi engavamile kodwa ekhathazayo ingabandakanya:

• Isiyezi noma ukukhathala
• Isicanucanu noma isisu esibuhlungu
• Ukukhathala emini
• Ushintsho lwemizwa noma ukucasuka

Uma uthola imiphumela emibi eqhubekayo noma ekhathazayo, unganqikazi ukuxhumana nomhlinzeki wakho wezempilo. Bangasiza ekunqumeni ukuthi umuthi ukufanele yini noma ngabe kudingeka izinguquko.

Imiphumela emibi engavamile kodwa engathi sína edinga ukunakekelwa kwezokwelapha ngokushesha ihlanganisa ukusabela okukhulu komzimba, izinguquko ezinkulu zemizwa, noma imicabango yokuzilimaza. Nakuba lokhu kungavamile, kubalulekile ukukwazi.

Ubani Ongafanele Athathwe I-Tasimelteon?

I-Tasimelteon ayifanele wonke umuntu. Udokotela wakho uzoqapha ngokucophelela ukuthi lo muthi uphephile yini esimweni sakho ngaphambi kokuwubhala.

Akufanele uthathe i-tasimelteon uma wazi ukuthi unokungezwani komzimba nomuthi noma yiziphi izithako zawo. Njalo yazisa udokotela wakho nganoma yikuphi ukusabela komzimba okwenzeke ngaphambilini emithini.

Abantu abanezinkinga ezinkulu zesibindi kufanele bagweme lo muthi, njengoba isibindi sisebenzisa i-tasimelteon. Uma unesifo sesibindi, udokotela wakho uzodinga ukucabangela ezinye izindlela zokwelapha noma akuqaphele eduze uma i-tasimelteon ibhaliwe.

Abesifazane abakhulelwe nabancelisayo kufanele baxoxe ngezingozi nezinzuzo nodokotela wabo. Ukuphepha kwe-tasimelteon ngesikhathi sokukhulelwa nokuncelisa akukatholakali ngokugcwele.

Izingane nentsha ngokuvamile abanikezwa i-tasimelteon, njengoba ucwaningo oluningi lugxile kubantu abadala. Udokotela wakho uzocabangela ezinye izindlela ezifanele ubudala ezigulini ezincane.

Amagama Omkhiqizo we-Tasimelteon

I-Tasimelteon itholakala ngaphansi kwegama lomkhiqizo elithi Hetlioz e-United States. Lolu uhlobo oluvame kakhulu ukunikezwa ngemithi.

I-Hetlioz yenziwa yi-Vanda Pharmaceuticals futhi iyinguqulo ye-tasimelteon evunywe yi-FDA. Uma udokotela wakho ekunikeza i-tasimelteon, lokhu kungenzeka ukuthi umkhiqizo othile ozowuthola ekhemisi.

Njalo qiniseka ukuthi uthola umkhiqizo kanye nomthamo ofanele njengoba unikezwe udokotela wakho. Izinhlobo ezivamile zingase zitholakale esikhathini esizayo, kodwa njengamanje, i-Hetlioz iyindlela yokuqala.

Ezinye Izindlela ze-Tasimelteon

Uma i-tasimelteon ingakulungele, ukwelashwa okuningana okuhlukile kungasiza ekuphatheni izifo ze-circadian rhythm. Udokotela wakho uzosebenza nawe ukuthola inketho engcono kakhulu yesimo sakho esithile.

Izithasiselo ze-Melatonin zivame ukuzanywa kuqala, njengoba zitholakala ngaphandle kwe-counter futhi zisebenza ngendlela efana ne-tasimelteon. Kodwa-ke, zingase zingasebenzi kahle ezifweni ezinzima ze-circadian rhythm.

Ukwelashwa ngokukhanya kungasiza abanye abantu, ikakhulukazi labo abanezinkinga zokulala zokusebenza noma i-jet lag. Lokhu kuhilela ukuchayeka ekukhanyeni okuqhakazile ngezikhathi ezithile ukusiza ukusetha kabusha iwashi lakho langaphakathi.

Ukuguqulwa kwendlela yokuphila, okuhlanganisa ukugcina amashejuli okulala aqhubekayo nokudala izindawo zokulala ezingcono kakhulu, kungagcwalisa noma ngezinye izikhathi kuthathe indawo yokwelashwa ngemithi.

Eminye imithi yokulala kadokotela ingase icatshangelwe, nakuba isebenza ngendlela ehlukile kune-tasimelteon futhi ingase ingabhekiseli enkingeni ye-circadian rhythm eyisisekelo.

Ingabe i-Tasimelteon Ingcono Kune-Melatonin?

I-Tasimelteon ne-melatonin zisebenza ezindleleni ezifanayo ebuchosheni bakho, kodwa i-tasimelteon yakhelwe futhi yahlolwa ngokuqondile ngezifo ze-circadian rhythm. Ngokuvamile inamandla futhi iqhubeka njalo kune-melatonin etholakala ngaphandle kwemvume kadokotela.

Kubantu abane-Non-24-Hour Sleep-Wake Disorder, ikakhulukazi labo abangaboni, i-tasimelteon ikhombise ukusebenza kahle kakhulu uma iqhathaniswa nezithasiselo ze-melatonin ezivamile. Umuthi wakhelwe ngokuqondile ukuthi uqondise ama-receptors abaluleke kakhulu ekulawuleni i-circadian rhythm.

I-Melatonin ingaba yindawo enhle yokuqala ezindabeni ezincane zokuhlela ukulala, kodwa i-tasimelteon ngokuvamile igcinelwe izifo ze-circadian rhythm ezinzima noma eziqhubekayo. Udokotela wakho uzosiza ekunqumeni ukuthi iyiphi inketho efaneleka kakhulu esimweni sakho esithile.

Ukukhetha phakathi kwale mithi kuncike ekuqineni kwesimo sakho, indlela ozabela ngayo ekwelashweni kwangaphambilini, kanye nomlando wakho wezokwelapha.

Imibuzo Evame Ukubuzwa Mayelana ne-Tasimelteon

Ingabe i-Tasimelteon Iphephile Kubantu Abanesifo Sikashukela?

I-Tasimelteon ngokuvamile ithathwa njengephephile kubantu abanesifo sikashukela, kodwa kufanele ngaso sonke isikhathi wazise udokotela wakho ngesimo sakho sesifo sikashukela ngaphambi kokuqala noma yimuphi umuthi omusha. Izifo zokulala ngezinye izikhathi zingathinta ukulawulwa kukashukela egazini, ngakho ukuthuthukisa iphethini yakho yokulala nge-tasimelteon kungase ngempela kusize ngokuphatha isifo sikashukela.

Udokotela wakho angase afune ukuqapha amazinga akho kashukela egazini eduze lapho uqala ukuthatha i-tasimelteon, ikakhulukazi uma unzima ukulawula isifo sakho sikashukela. Lokhu ikakhulukazi kuyisinyathelo sokuzivikela ukuqinisekisa ukuthi umuthi awuphazamisi ukwelashwa kwakho isifo sikashukela.

Ngingenzani Uma Ngenhlanhla Ngithatha I-Tasimelteon Eningi Kakhulu?

Uma ngabe uthatha ngengozi umthamo omningi we-tasimelteon kunalowo odokotela bakunike wona, xhumana nodokotela wakho noma isikhungo esilawula ubuthi ngokushesha. Nakuba ukweqisa imithamo kungavamile, kubalulekile ukufuna usizo lwezokwelapha nganoma yikuphi ukweqisa imithamo yemithi.

Izimpawu zokuthatha okuningi zingase zihlanganise ukozela ngokweqile, ukudideka, noma ukuzizwa ungaphilile. Ungazami ukulwa nomthamo owengeziwe ngokuhlala uvukile noma ukuphuza i-caffeine, ngoba lokhu kungaphazamisa ukusebenza kahle komuthi.

Ukuvimbela ukweqisa imithamo ngengozi, qaphela ukuthi uyithatha nini imithi yakho futhi cabangela ukusebenzisa umhleli wamaphilisi uma unzima ukukhumbula ukuthi ngabe uyithathile yini umthamo wakho wansuku zonke.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Tasimelteon?

Uma uphuthelwa umthamo we-tasimelteon, yithathe ngokushesha lapho ukhumbula, kodwa kuphela uma kuseseduze nesikhathi sakho sokulala esivamile. Uma sekuhlwile ebusuku noma sekuseduze ekuseni, weqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esivamile.

Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe. Lokhu kungandisa ingozi yakho yemiphumela engemihle futhi ngeke kuthuthukise ukusebenza kahle komuthi.

Ukuphuthelwa umthamo ngezikhathi ezithile ngokuvamile ngeke kubangele izinkinga ezinkulu, kodwa zama ukugcina ukuqina ukuze uthole imiphumela engcono kakhulu. Cabangela ukusetha isikhumbuzi sansuku zonke ocingweni lwakho ukukusiza ukuthi ukhumbule ukuthatha imithi yakho.

Ngingayeka nini ukuthatha i-Tasimelteon?

Kufanele uyeke kuphela ukuthatha i-tasimelteon ngaphansi kwesiqondiso sikadokotela wakho. Ngokungafani neminye imithi yokulala engayekwa ngokuphazima kweso, i-tasimelteon isebenza kahle kakhulu uma iyekwa kancane kancane ukuze kugcinwe ukuthuthuka kwephethini yokulala okuyifinyelele.

Udokotela wakho uzohlola amaphethini akho okulala nokuphendula kwakho konke ukuze anqume isikhathi esifanele sokunciphisa noma ukuyeka imithi. Abanye abantu bangase badinge ukuqhubeka beyithatha isikhathi eside, kanti abanye bangase bakwazi ukugcina isimiso sabo sokulala esithuthukisiwe ngaphandle kwayo.

Ungayeki ukuthatha i-tasimelteon ngokuzumayo ngenxa yokuthi uzizwa ungcono. Indlela yakho yokulala ethuthukisiwe ingancika emiphumeleni eqhubekayo yomuthi, futhi ukuyeka kungazelelwe kungabangela ukuthi izinkinga zakho zokulala zibuye.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Tasimelteon?

Kungcono ukugwema utshwala ngenkathi uthatha i-tasimelteon, njengoba zombili lezi zinto zingabangela ukozela futhi zingase zisebenzisane ngezindlela ezingaqondakali. Utshwala bungaphazamisa nekhwalithi yakho yokulala, okusebenza ngokumelene nemiphumela yomuthi ehlosiwe.

Uma ukhetha ukuphuza utshwala ngezikhathi ezithile, kwenze kahle ngaphambi kokulala kwakho kanye nomthamo we-tasimelteon. Ngisho namanani amancane otshwala angaphazamisa ikhono lomuthi lokulawula umjikelezo wakho wokulala-ukuphaphamuka ngempumelelo.

Xoxa nodokotela wakho mayelana nemikhuba yakho yokuphuza utshwala ukuze bakwazi ukukunikeza isiqondiso esiqondene nawe esisekelwe esimweni sakho esithile kanye nemigomo yokwelashwa.