Yini i-Tiagabine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Tiagabine iyimithi kadokotela esetshenziselwa ikakhulukazi ukwelapha isithuthwane, ikakhulukazi ukuquleka okuyingxenye okungazange kuphendule kahle kwezinye izindlela zokwelapha. Isebenza ngokuthinta amakhemikhali athile obuchopho alawula umsebenzi kagesi, okusiza ukunciphisa imvamisa nobukhulu bokuquleka kubantu abadinga ukulawulwa okwengeziwe kokuquleka.

Le mithi ingeyeqembu lezidakamizwa elibizwa ngokuthi ama-anticonvulsants noma izidakamizwa ze-antiepileptic. Ngenkathi ithathwa njengendlela yokwelapha ekhethekile, ukuqonda ukuthi isebenza kanjani nokuthi yini ongayilindela kungakusiza uzizwe uqiniseka kakhulu ngohlelo lwakho lokwelapha.

Yini i-Tiagabine?

I-Tiagabine iyimithi ye-antiepileptic esiza ukulawula ukuquleka ngokulawula umsebenzi wobuchopho. Yenzelwe ngqo abantu abokuquleka kwabo okungalawulwa ngokugcwele yimithi yabo yamanje, isebenza njengenketho yokwelapha eyengeziwe kunokwelashwa komugqa wokuqala.

Umuthi uza ngesimo samaphilisi futhi uthathwa ngomlomo. Yilokho odokotela abakubiza ngokuthi

Udktela wakho angase ancome i-tiagabine uma usuvele usebenzisa eminye imithi yokulwa nokuthuthumela kodwa usahlangabezana nokuthuthumela. Ilusizo ikakhulukazi kubantu abanezithuthumela eziyinkimbinkimbi noma izithuthumela ezilula ezingaphendulanga kahle kwezinye izindlela zokwelapha.

Umuthi uhlala usetshenziswa ngokuhlanganyela neminye imithi elwa nokuthuthumela, ungalokothi usetshenziswe njengendlela yokwelapha ezimele yodwa. Le ndlela isiza ukukhulisa ukulawulwa kokuthuthumela ngenkathi kunciphisa imiphumela engemihle engase ivele ngemithamo ephezulu yomuthi owodwa.

Isebenza Kanjani I-Tiagabine?

I-Tiagabine isebenza ngokuvimba ukuthathwa kabusha kwamakhemikhali obuchopho abizwa nge-GABA (i-gamma-aminobutyric acid). I-GABA iyi-neurotransmitter yakho enkulu yobuchopho "ethulisayo", esiza ukunciphisa umsebenzi kagesi owedlulele ongaholela ekuthuthumeleni.

Lapho i-tiagabine ivimba ukuthathwa kabusha kwe-GABA, amakhemikhali amaningi athulisayo ahlala esebenza ebuchosheni bakho. Lokhu kusiza ukugcina imvelo kagesi ezinzile, okwenza ukuthi ukuthuthumela kungenzeki. Kufana nokuba nohlelo olusebenzayo lokubopha umsebenzi kagesi wobuchopho bakho.

Lo muthi ubhekwa njengonamandla ngokulinganisela phakathi kwemithi elwa nokuthuthumela. Awunamandla njengeminye imithi emisha, kodwa usebenza kahle ngokwanele ukuhlinzeka ngokuncishiswa okukhulu kokuthuthumela uma isetshenziswa kahle njengengxenye yohlelo olubanzi lokwelapha.

Kufanele Ngiyithathe Kanjani I-Tiagabine?

Thatha i-tiagabine ngendlela eqondile njengoba unqunyelwe udokotela wakho, ngokuvamile izikhathi ezi-2-4 ngosuku ngokudla. Ukuyithatha ngokudla kusiza ukunciphisa isisu esicasulayo futhi kuthuthukisa ukuthi umzimba wakho uyimunca kanjani imithi.

Gwinya amaphilisi wonke ngamanzi - ungaqobi, uhlafune, noma uwaphule. Udokotela wakho ngokuvamile uzoqala ngomthamo ophansi futhi awunyuse kancane kancane emasontweni amaningana. Lokhu kwenyuka kancane kusiza umzimba wakho ukuthi uzivumelanise futhi kunciphisa ingozi yemiphumela engemihle.

Zama ukuthatha imithamo yakho ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo ohlelweni lwakho. Uma uyithatha kabili ngosuku, hlukanisa imithamo ngamahora ayi-12. Ukuze uthole imithamo evame kakhulu, landela uhlelo oluqondile lukadokotela wakho.

Ngaphambi kokuthatha i-tiagabine, yidla okuthile okulula uma ungakadli muva nje. Ukudla okufana nama-crackers, isinkwa esosiwe, noma iyogathi kusebenza kahle. Gwema ukuyithatha esiswini esingenalutho ngokuphelele, njengoba lokhu kungakhuphula amathuba okuba nesiyezi noma isicanucanu.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Tiagabine?

I-Tiagabine ngokuvamile iyindlela yokwelapha isikhathi eside ye-epilepsy, evame ukuthathwa iminyaka eminingi noma ingunaphakade. Ubude besikhathi sincike ekulawuleni kwakho ukuhlaselwa, ukuthi uyithatha kahle kangakanani imithi, kanye nemigomo yakho yokwelapha iyonke.

Abantu abaningi badinga ukuthatha i-tiagabine ngokuqhubekayo ukuze balawule ukuhlaselwa. Ukuyeka kungazelelwe kungabangela ukuhlaselwa okusha noma ngisho ne-status epilepticus, isimo esiyingozi lapho ukuhlaselwa kungami ngokwako. Udokotela wakho uzoqapha inqubekela phambili yakho njalo ukuze aqinisekise ukuthi imithi iyaqhubeka isebenza.

Uma wena nodokotela wakho ninquma ukuyeka i-tiagabine, uzodinga ukuyeka kancane kancane phakathi namasonto amaningana noma izinyanga. Lokhu kwehla kancane kusiza ekuvikeleni ukuhlaselwa kokuhoxiswa futhi kuvumela ubuchopho bakho ukuthi buvumelane noshintsho emazingeni emithi.

Yiziphi Imiphumela Eceleni Ye-Tiagabine?

Njengayo yonke imithi, i-tiagabine ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi ilula kuya kokulingene futhi ivame ukuthuthuka njengoba umzimba wakho uvumelana nemithi.

Nawa imiphumela emibi evame kakhulu ongase uyithole lapho uqala i-tiagabine:

• Isiyezi noma ukukhathala
• Ukukhathala noma ukozela
• Isicanucanu noma isisu esibuhlungu
• Ukukhathazeka noma ukukhathazeka
• Ukuthuthumela noma ukuzamazama
• Ubunzima bokugxilisa ingqondo
• Ubuthakathaka noma ukukhathala

Lezi zinto zivame ukwenzeka emasontweni ambalwa okuqala okwelashwa futhi zivame ukuncipha njengoba umzimba wakho ujwayela umuthi.

Abanye abantu bangase babe nemiphumela emibi ekhathazayo edinga ukunakekelwa kwezempilo ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukwazi:

• Ukudideka okukhulu noma ukulahlekelwa yisikhundla
• Ukucabanga noma ukubona izinto ezingekho
• Ushintsho olukhulu lwemizwa noma ukucindezeleka
• Imicabango yokuzilimaza
• Ukuqubuka okukhulu kwesikhumba noma ukusabela komzimba ngaphandle
• Ukushaywa yisithuthwane okuba njalo noma kube kubi kakhulu

Xhumana nodokotela wakho ngokushesha uma uhlangabezana nanoma yimiphi yale miphumela emibi kakhulu. Bangasiza ukulungisa uhlelo lwakho lokwelashwa ukuze luhambisane kangcono nezidingo zakho.

Ubani Ongafanele Athathwe I-Tiagabine?

I-Tiagabine ayifanele wonke umuntu, futhi izimo ezithile noma izimo zingase zikwenze kungaphephile ukuthatha lo muthi. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuwubhala.

Akufanele uthathe i-tiagabine uma unokungezwani nayo noma yiziphi izithako zayo. Abantu abanezinhlobo ezithile zokushaywa yisithuthwane, ikakhulukazi ukushaywa yisithuthwane okujwayelekile, kufanele bagweme lo muthi njengoba empeleni ungenza ezinye izinhlobo zokushaywa yisithuthwane zibe zimbi kakhulu.

Ukuqapha okukhethekile kuyadingeka uma unezinkinga zesibindi, njengoba i-tiagabine icutshungulwa yisibindi. Udokotela wakho kungase kudingeke ukuthi alungise umthamo wakho noma akuqaphe eduze uma unesifo sesibindi. Abantu abanomlando we-status epilepticus (ukushaywa yisithuthwane okude) bangase badinge nokuqapha ngokucophelela.

Abesifazane abakhulelwe kufanele baxoxe ngezingozi nezinzuzo nodokotela wabo, njengoba i-tiagabine ingase ithinte ukukhula kwengane esesizalweni. Uma uhlela ukukhulelwa noma usuvele ukhulelwe, udokotela wakho uzokusiza ukuthi ulinganise izinzuzo zokulawula ukushaywa yisithuthwane nezingozi ezingaba khona.

Amagama Omkhiqizo we-Tiagabine

I-Tiagabine iyatholakala ngaphansi kwegama lomkhiqizo elithi Gabitril e-United States. Le yindlela evame kakhulu ukunqunywa ngayo imithi futhi ikhiqizwa yi-Cephalon, manje eyinxenye ye-Teva Pharmaceuticals.

Izinhlobo ze-generic ze-tiagabine nazo ziyatholakala, eziqulathe isithako esifanayo esisebenzayo kodwa zingase zibe ngentengo ephansi. Ikhemisi lakho lingakusiza ukuthi uqonde ukuthi ngabe izinketho ze-generic ziyatholakala futhi zihlanganiswe yini ngumshuwalense wakho.

Noma ngabe uthatha i-Gabitril yegama lomkhiqizo noma i-tiagabine ye-generic, imithi isebenza ngendlela efanayo. Abanye abantu bakhetha ukunamathela kumkhiqizi oyedwa ukuqinisekisa ukuvumelana, kanti abanye bazizwa bekhululekile ukushintshana phakathi kwezinhlobo ze-generic nezomkhiqizo.

Ezinye izindlela ze-Tiagabine

Imithi eminingana ehlukile ingasetshenziswa uma i-tiagabine ingakulungele noma inganikezi ukulawulwa okwanele kokuhlaselwa. Lezi zindlela ezihlukile zisebenza ngezindlela ezihlukene kodwa zisebenzela izinjongo ezifanayo ekwelashweni kwesithuthwane.

Ezinye izindlela ezivamile zifaka i-levetiracetam (Keppra), evame ukubekezelelwa kahle futhi isebenza kahle ekuhlaselweni okuyingxenye. I-Lamotrigine (Lamictal) enye inketho engasetshenziswa ngezinhlobo ezahlukene zokuhlaselwa futhi inezinhlangothi ezinhle zokusebenza kwabantu abaningi.

Ezinye izindlela zifaka i-topiramate (Topamax), i-gabapentin (Neurontin), kanye ne-pregabalin (Lyrica). Ngayinye inezinzuzo zayo kanye nemiphumela engaba khona, ngakho udokotela wakho uzokusiza ukuthi uthole inketho engcono kakhulu ngokususelwa ezidingweni zakho ezithile nomlando wezokwelapha.

Ukukhetha okunye kuncike ezintweni ezifana nohlobo lwakho lokuhlaselwa, eminye imithi oyithathayo, iminyaka yakho, nanoma yiziphi ezinye izimo zezempilo onazo. Udokotela wakho uzosebenza nawe ukuthola inketho esebenza kahle kakhulu futhi ebekezelelekayo.

Ingabe i-Tiagabine ingcono kune-Carbamazepine?

I-Tiagabine ne-carbamazepine (Tegretol) zisebenza ngendlela ehlukile futhi zifeza izindima ezehlukene ekwelashweni kwesithuthwane. I-Carbamazepine ivame ukusetshenziswa njengokwelashwa kokuqala kwezithuthwane ezingaphelele, kanti i-tiagabine ngokuvamile ingezwa uma ukwelashwa kokuqala kungasebenzi ngokugcwele.

I-Carbamazepine isetshenziswe isikhathi eside futhi inocwaningo oluningi olusekela ukusetshenziswa kwayo njengokwelashwa okuyinhloko. Kodwa-ke, i-tiagabine inikeza izinzuzo kwabanye abantu, ikakhulukazi labo abathola imiphumela emibi evela ku-carbamazepine noma abadinga ukulawulwa okwengeziwe kwezithuthwane.

Ukwenza okungcono kuncike esimweni sakho ngasinye. I-Carbamazepine ingase ithandwe uma usanda kutholwa ukuthi unaso futhi uqala ukwelashwa, kanti i-tiagabine ingase ibe ngcono uma udinga ukulawulwa okwengeziwe kwezithuthwane noma uke waba nezinkinga ngeminye imithi.

Udokotela wakho uzocabangela izinto ezinjengohlobo lwakho lwezithuthwane, eminye imithi, ukusebenzisana okungenzeka kwemithi, nomlando wakho wezempilo lapho enquma phakathi kwalezi zinketho. Abantu abaningi empeleni bathatha yomibili imithi ndawonye ukuze kulawulwe kahle izithuthwane.

Imibuzo Evame Ukubuzwa Mayelana ne-Tiagabine

Q1. Ingabe i-Tiagabine iphephile ezigulini ezinokugula kwezinso?

I-Tiagabine ngokuvamile ithathwa njengephephile kubantu abanezifo zezinso ngoba ngokuyinhloko icutshungulwa yisibindi kunokuba izinso. Izinso zakho akudingeki zisebenze kanzima ukuze ziqede lo muthi emzimbeni wakho.

Kodwa-ke, uma unezifo ezinzima zezinso, udokotela wakho angase afune ukukuqapha eduze lapho uqala i-tiagabine. Lokhu kungenxa yokuthi izifo zezinso ngezinye izikhathi zingathinta indlela umzimba wakho osabela ngayo emithini, ngisho naleyo engacutshungulwa ngqo izinso.

Q2. Kufanele ngenzeni uma ngiphuzile i-Tiagabine eningi ngengozi?

Uma ngengozi uphuza i-tiagabine eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma uzizwa kahle. Ukuphuza okuningi kungaholela emiphumeleni emibi engathi sína njengobuthongo obukhulu, ukudideka, noma ngisho nokoma.

Ungalindi ukuthi izimpawu zivele ngaphambi kokufuna usizo. Gcina ibhodlela lemithi nawe ukuze ukwazi ukutshela ochwepheshe bezokwelapha ukuthi yini kanye nokuthi ungakanani okuthathile. Uma othile engazi lutho noma enobunzima bokuphefumula, shayela izinsiza eziphuthumayo ngokushesha.

Q3. Kufanele Ngenzeni Uma Ngedlula Umthamo We-Tiagabine?

Uma udlula umthamo we-tiagabine, yithathe ngokushesha lapho ukhumbula, kodwa kuphela uma ingasondeli emthomeni wakho olandelayo ohleliwe. Uma sekuyisikhathi somthamo wakho olandelayo, weqa umthamo odluliwe bese uqhubeka neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo odluliwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabanga ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi ukukusiza ukuthi uhlale emgqeni.

Q4. Ngingayeka Nini Ukuthatha I-Tiagabine?

Kufanele uyeke kuphela ukuthatha i-tiagabine ngaphansi kokuqondisa kukadokotela wakho. Ukuyeka kungazelelwe kungabangela ukuquleka noma ukuquleka kokuhoxiswa, okungaba yingozi futhi okungase kubeke impilo engozini.

Udkt. wakho ngokuvamile uzokwehlisa umthamo wakho kancane kancane emasontweni amaningana noma izinyanga uma udinga ukuyeka umuthi. Le nqubo yokunciphisa kancane kancane isiza ekuvikeleni ukuquleka kokuhoxiswa futhi ivumela ubuchopho bakho ukuthi buvumelane noshintsho emazingeni emithi.

Q5. Ngingashayela Ngenkathi Ngithatha I-Tiagabine?

Ukushayela ngenkathi uthatha i-tiagabine kuncike ekutheni umuthi ukuthinta kanjani nokulawulwa kwakho kokuquleka. Umuthi ungabangela isiyezi, ukozela, noma izinkinga zokugxilisa ingqondo, ikakhulukazi uma uqala ukuwuthatha.

Okubaluleke kakhulu, kufanele ulandele imithetho yakho yendawo yokushayela ephathelene nesithuthwane, okujwayele ukukudinga ukuthi ungabi nokuquleka isikhathi esithile ngaphambi kokushayela. Khuluma nodokotela wakho mayelana nokuthi kungaba nini kuphephile ukuthi ushayele, ucabangela kokubili ukulawulwa kwakho kokuquleka kanye nanoma yimiphumela emibi evela ku-tiagabine.