Yini i-Tolterodine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Tolterodine iyikhambi elibhalwe ngudokotela elisiza ukulawula isinye esisebenza ngokweqile. Isebenza ngokukhulula imisipha yesinye, okunciphisa leyo mizwa engazelelwe, ephuthumayo yokuchama engaphazamisa impilo yakho yansuku zonke.

Uma ubhekene nokuvakashela indlu yangasese njalo noma lowo muzwa ongamnandi wokuthi awukwazi ukuzibamba, awuwedwa. Izigidi zabantu zithola lezi zimpawu, futhi i-tolterodine inikeza indlela efakazelwe yokusiza ukuzilawula ngokuphepha nangempumelelo.

Yini i-Tolterodine?

I-Tolterodine ingeyeqembu lemithi ebizwa ngokuthi ama-antimuscarinics noma ama-anticholinergics. Cabanga ngayo njengebhegi elithambile lemisipha yesinye sakho uma isebenza kanzima kakhulu.

Isinye sakho sinemisipha ekhontraktha ukuze ikhiphe umchamo uma usulungele ukuya. Ngezinye izikhathi le misipha iba ngaphezu komsebenzi futhi icindezele lapho ingafanele. I-Tolterodine isiza ukuthulisa lo msebenzi ngokuvala izimpawu ezithile zemizwa ezitshela isinye sakho ukuthi sinciphise.

Lo muthi uza ngezindlela ezimbili: amaphilisi akhishwa ngokushesha owathatha kabili ngosuku, nama-capsules akhishwa isikhathi eside owathatha kanye ngosuku. Zombili zisebenza ngempumelelo, kodwa inguqulo yokukhishwa isikhathi eside inikeza lula lokuthatha njalo.

Isetshenziselwani i-Tolterodine?

I-Tolterodine iphatha i-overactive bladder syndrome, isimo lapho imisipha yesinye sakho icindezela kaningi noma ngezikhathi ezingafanele. Lokhu kudala lezo zimpawu ezicasulayo ezingakwenza uzizwe sengathi uhlala uhlela usuku lwakho ezindaweni zokugezela.

Umuthi usiza ngokuqondile ngezimpawu ezintathu eziqhelelene. Okokuqala, inciphisa imvamisa yokuchama, okusho ukuthi ngeke kudingeke ukuthi uchame njalo usuku lonke. Abantu abaningi bathola ukuthi bangahlala isikhathi eside phakathi kokuvakashela indlu yangasese uma umuthi uqala ukusebenza.

Okwesibili, i-tolterodine isiza ukulawula ukuphuthuma - lowo muzwa ongazelelwe, onamandla wokuthi udinga ukuchama ngokushesha. Lesi simo singaba esicindezela kakhulu ngoba sivame ukuza ngaphandle kwesixwayiso futhi kungaba nzima ukungasinaki.

Okwesithathu, kungasiza ekuvikeleni ukungakwazi ukuzibamba, okwenzeka uma uvuza umchamo ngoba awukwazi ukufika endlini yangasese ngesikhathi. Lokhu kwenzeka lapho umuzwa ophuthumayo unamandla kangangokuthi imisipha yakho yesinye iqala ukuzwana ngaphambi kokuthi ulunge.

Isebenza Kanjani I-Tolterodine?

I-Tolterodine ithathwa njengomuthi onamandla ngokulinganisela osebenza ngokuvimba izamukeli ezithile emsipheni wakho wesinye. Lezi zamukeli, ezibizwa ngokuthi ama-muscarinic receptors, ngokuvamile zithola amasignali avela ohlelweni lwakho lwezinzwa olutshela isinye sakho ukuthi sizwane nini.

Uma uthatha i-tolterodine, ihlala kulezi zamukeli njengomqaphi omuhle, ivimbela amanye amasignali abangela ukuzwana okungafuneki kwesinye. Lokhu akuyeki isinye sakho ukuthi sisebenze ngokujwayelekile uma empeleni udinga ukuchama - kumane kunciphisa ukuminyana okweqile okwenzeka ngezikhathi ezingafanele.

Umuthi wakha ohlelweni lwakho ngokuhamba kwesikhathi, yingakho ungase ungaboni imiphumela ephelele ngokushesha. Abantu abaningi baqala ukuzwa ukuthuthuka okuthile ngesonto lokuqala, kodwa kungathatha amasonto angu-4-8 ukuzwa izinzuzo eziphezulu.

Kufanele Ngiyithathe Kanjani I-Tolterodine?

Thatha i-tolterodine ngendlela eqondile udokotela wakho ayichazayo, ngokuvamile kanye noma kabili ngosuku kuye ngokuthi usebenzisa yiphi ifomu. Ungayithatha nokudla noma ngaphandle kokudla, nakuba ukuyithatha nokudla kungasiza uma uba nesisu esibuhlungu.

Uma uthatha amaphilisi akhishwa ngokushesha, ngokuvamile uzothatha ithebhulethi eyodwa kabili ngosuku, cishe ngamahora angu-12 ahlukene. Zama ukuzithatha ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo emzimbeni wakho. Abantu abaningi bakuthola kuwusizo ukuxhumanisa imithamo yabo nemisebenzi evamile efana nesidlo sasekuseni nesidlo sakusihlwa.

Ngemithi yokukhishwa isikhathi eside, uzothatha ikhaphule elilodwa kanye ngosuku, okungcono ngesikhathi esifanayo nsuku zonke. Gwinya ikhaphule lonke - ungaliqhekezi, ulilume, noma ulivule, ngoba lokhu kungathinta indlela umuthi okhishwa ngayo emzimbeni wakho.

Ungathatha i-tolterodine ngamanzi, ijusi, noma olunye uhlobo lwesiphuzo osithandayo. Akukho mingcele ethile yokudla, nakuba ukuhlala unamanzi kahle kubalulekile empilweni yonke yesinye.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Tolterodine?

Abantu abaningi bathatha i-tolterodine izinyanga eziningana kuya eminyakeni, kuye ngezimpawu zabo nokuthi umuthi usebenza kahle kangakanani kubo. Udokotela wakho uzosiza ekunqumeni ubude obufanele ngokuya ngesimo sakho somuntu ngamunye.

Abanye abantu baqaphela ukuthuthuka ngesonto lokuqala, kodwa kubalulekile ukunika umuthi okungenani amasonto angu-4-8 ukufinyelela ekusebenzeni kwawo okuphelele. Ngesikhathi esinjalo, udokotela wakho angase alungise umthamo wakho noma ahlole ukuthi usabela kanjani ekwelashweni.

Abantu abaningi bathatha i-tolterodine isikhathi eside ngoba isinye esisebenza ngokweqile sivame ukuba yisimo esingapheli esizuzayo ekuphathweni okuqhubekayo. Kodwa-ke, udokotela wakho angase aphakamise ngezikhathi ezithile ukuzama ukuphumula emuthini ukuze abone ukuthi izimpawu zakho zithuthukile yini ngokwemvelo.

Yiziphi Imiphumela Eceleni Ye-Tolterodine?

Njengayo yonke imithi, i-tolterodine ingabangela imiphumela emibi, nakuba abantu abaningi behlangabezana nemiphumela emibi emincane noma engekho nhlobo. Imiphumela emibi evame kakhulu ivamise ukulawuleka futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi ongase uhlangabezane nayo, ukhumbula ukuthi wonke umuntu usabela ngendlela ehlukile emithini:

• Umlomo owomile - lokhu kuthinta cishe u-35% wabantu futhi kuwumphumela ovamile kakhulu
• Ukuqunjelwa - kwenzeka cishe ku-7% yabantu abathatha umuthi
• Ikhanda elibuhlungu - lithinta cishe u-7% wabasebenzisi
• Isiyezi - okuhlangenwe nakho ngabantu abangaba ngu-5%
• Amehlo omile - akuvamile kodwa kungenzeka
• Ukubona okungacacile - ngokuvamile kulula futhi okwesikhashana
• Ukuphazamiseka kwesisu noma ukungagayeki kahle kokudla - ukuthatha ngokudla kungasiza

Le miphumela evamile ngokuvamile imnene futhi ivame ukungabonakali njengoba umzimba wakho ujwayela umuthi. Uma umlomo owomile ukukhathaza, zama uswidi ongenashukela noma ukunatha amanzi njalo.

Imiphumela engavamile kodwa ebucayi idinga ukunakekelwa kwezokwelapha ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukwazi ukuze ukwazi ukufuna usizo uma kudingeka.

Xhumana nodokotela wakho ngokushesha uma uhlangabezana nanoma yimiphi yale miphumela engavamile kodwa ebucayi:

• Ukuqunjelwa okukhulu okungathuthuki ngokwelashwa
• Ubunzima bokuchama noma ukungakwazi ukuchama ngokuphelele
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Isiyezi esikhulu noma ukuquleka
• Izimpawu zokungezwani komzimba nezinto ezithile njengokuqubuka, ukuvuvukala, noma ubunzima bokuphefumula
• Ukudideka noma izinkinga zenkumbulo
• Ubuhlungu obukhulu besisu

Ngokuvamile kakhulu, abanye abantu bangase bahlangabezane nezinkinga ezingathi sína njengokugcinwa komchamo (ukungakwazi ukukhipha isinye) noma ukushaywa ukushisa ngenxa yokuncipha kokujuluka. Lokhu kungenzeka kakhulu esimweni sezulu esishisayo noma ngesikhathi somsebenzi onzima.

Ubani Ongafanele Athole I-Tolterodine?

I-Tolterodine ayiphephile kuwo wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Izimo ezithile zingenza lo muthi ube yingozi noma ungasebenzi kahle kuwe.

Akufanele uthathe i-tolterodine uma unokugcinwa komchamo okuphelele, okusho ukuthi awukwazi ukuchama nhlobo. Umuthi ungenza lesi simo sibe sibi ngokwengeziwe ngokuphumuza imisipha yesinye sakho.

Abantu abanezinkinga zokugcina ukudla esiswini (izinkinga ezinkulu zokukhipha isisu) kufanele futhi bagweme i-tolterodine. Lokhu kufaka phakathi izimo ezinjenge-gastroparesis enkulu, lapho ukudla kuhamba kancane kakhulu ngohlelo lwakho lokugaya ukudla.

Uma une-glaucoma engalawuleki ye-narrow-angle, i-tolterodine ingakhuphula ingcindezi emehlweni akho futhi ingase ibangele izinkinga zokubona. Udokotela wakho wamehlo angathola ukuthi unayo yini lolu hlobo lwe-glaucoma.

Ezinye izimo eziningana zidinga ukuqapha okwengeziwe lapho kucatshangelwa i-tolterodine. Udokotela wakho uzokala izinzuzo ngokumelene nezingozi ezingaba khona uma unanoma yiziphi zalezi zimo:

• Isifo sezinso - ungase udinge umthamo ophansi
• Isifo sesibindi - umuthi uqhutshwa yisibindi sakho
• Izinkinga zesigqi senhliziyo - i-tolterodine ingathinta izinga lenhliziyo yakho
• I-Myasthenia gravis - isimo sokuba buthakathaka kwemisipha
• I-prostate enwetshiwe emadodeni - ingenza izinkinga zokuchama zibe zimbi kakhulu
• Ukuqunjelwa okukhulu noma ukuvinjelwa kwamathumbu
• I-glaucoma ye-narrow-angle elawulwayo

Ubudala bungaba yisici futhi, njengoba abadala bengase bazwe imiphumela emibi efana nokudideka, isiyezi, noma ukuqunjelwa. Udokotela wakho angase akuqale ngomthamo ophansi uma uneminyaka engaphezu kwengama-65.

Amagama Omkhiqizo we-Tolterodine

I-Tolterodine itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Detrol ne-Detrol LA okuyizona ezaziwa kakhulu. I-Detrol ibhekisela kumaphilisi akhishwa ngokushesha, kuyilapho i-Detrol LA iyisithako esikhishwe isikhathi eside.

Izinhlobo ezivamile ze-tolterodine nazo ziyatholakala futhi zisebenza ngempumelelo njengezinhlobo zegama lomkhiqizo. Imithi ejwayelekile iqukethe isithako esifanayo esisebenzayo futhi ihlangabezana namazinga afanayo ekhwalithi, ngokuvamile ngentengo ephansi.

Ikhemisi lakho lingase lithwale izinhlobo ezahlukene zabakhiqizi be-tolterodine ejwayelekile. Ngenkathi zilingana ekusebenzeni, ungase uqaphele umehluko omncane ekubukekeni noma ezithakweni ezingasebenzi phakathi kwemikhiqizo.

Ezinye izindlela ze-Tolterodine

Uma i-tolterodine ingasebenzi kahle kuwe noma ibangela imiphumela engathandeki, eminye imithi eminingi ingelapha isinye esisebenza ngokweqile. Udokotela wakho angakusiza ukuthi uthole enye engcono kakhulu ngokusekelwe ezidingweni zakho ezithile nomlando wakho wezokwelapha.

Eminye imithi ye-anticholinergic isebenza ngendlela efana ne-tolterodine kodwa ingase ibe nemiphumela ehlukile. I-Solifenacin (Vesicare) ithathwa kanye ngosuku futhi ingase ibangela umlomo owomile kancane kwabanye abantu. I-Darifenacin (Enablex) yakhelwe ukuthi ikhetheke kakhulu kuma-receptors esinye, okungenzeka ukuthi kunciphisa eminye imiphumela.

I-Oxybutynin ingenye yemithi endala kulesi sigaba futhi iza ngezinhlobo eziningi, okuhlanganisa amaphilisi, amaphilisi akhishwe isikhathi eside, ngisho nesiqeshana sesikhumba. Isiqeshana singasiza uma unzima ukukhumbula ukuthatha imithi yansuku zonke.

Imithi emisha ebizwa ngokuthi ama-beta-3 agonists isebenza ngendlela ehlukile kune-tolterodine. I-Mirabegron (Myrbetriq) iphumuza imisipha yesinye ngendlela ehlukile futhi ngokuvamile ayibangeli umlomo owomile noma ukuqunjelwa.

Ukwelashwa okungekona okwemithi kungasebenza kahle kakhulu, kungaba ngawodwa noma kuhlanganiswe nemithi. Lokhu kufaka phakathi ukuzivocavoca ukuqeqeshwa kwesinye, ukwelashwa ngokomzimba komgogodla we-pelvic, kanye nokuguqulwa kwendlela yokuphila njengokukhipha ngesikhathi.

Ingabe i-Tolterodine Ingcono Kune-Oxybutynin?

Kokubili i-tolterodine ne-oxybutynin kuyasebenza ekwelapheni isinye esisebenza ngokweqile, kodwa zinezinto ezihlukile ezingenza enye ilungele kangcono isimo sakho esithile.

I-Tolterodine ngokuvamile ithathwa njengembangela imiphumela emincane, ikakhulukazi umlomo owomile omncane nokuqunjelwa. Ucwaningo lubonisa ukuthi abantu maningi amathuba okuqhubeka nokuthatha i-tolterodine isikhathi eside ngoba ithuthukiswa kangcono.

I-Oxybutynin isikhona isikhathi eside futhi itholakala ngezindlela eziningi, okuhlanganisa isiqeshana osishintsha kabili ngesonto. Futhi ngokuvamile ayibizi kakhulu, ikakhulukazi ngesimo esivamile. Kwabanye abantu, i-oxybutynin isebenza kangcono ekulawuleni izimpawu zabo.

Ukukhetha phakathi kwala mithi kuvame ukuncika ekuphenduleni komuntu ngamunye nokubekezelela. Abanye abantu benza ngcono ngephrofayili yomphumela ohlangothini oluthambile lwe-tolterodine, kanti abanye bathola i-oxybutynin isebenza ngempumelelo kakhulu ezimpawini zabo naphezu kwemiphumela engase ibe khona.

Udokotela wakho uzocabangela izinto ezinjengobudala bakho, eminye imithi oyithathayo, nanoma yiziphi izimo zezokwelapha onazo lapho encoma ukuthi iyiphi imithi okufanele uzame kuqala.

Imibuzo Evame Ukubuzwa Mayelana ne-Tolterodine

Ingabe i-Tolterodine iphephile ezigulini zenhliziyo?

I-Tolterodine ingasetshenziswa ngabantu abanezifo zenhliziyo, kodwa idinga ukuqashwa ngokucophelela ngudokotela wakho. Umuthi ungase ukwazi ukuthinta ukushaya kwenhliziyo yakho, ikakhulukazi uma usuvele unezifo zenhliziyo ezithile.

Uma unomlando wezinkinga zokushaya kwenhliziyo, udokotela wakho angase afune ukwenza i-electrocardiogram (EKG) ngaphambi kokuqala i-tolterodine futhi mhlawumbe aqaphe ukushaya kwenhliziyo yakho ngezikhathi ezithile ngenkathi uyithatha.

Abantu abanezifo zenhliziyo ezilawulwa kahle bavame ukuthatha i-tolterodine ngokuphepha, kodwa kubalulekile ukutshela udokotela wakho ngayo yonke imithi yakho yenhliziyo. Ezinye izinhlanganisela zingase zidinge ukulungiswa kwemithamo noma ukuqashwa okwengeziwe.

Ngingenzani uma ngiphuthelwa ngengozi ukusebenzisa i-Tolterodine eningi?

Uma ngengozi uthatha i-tolterodine eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela imiphumela emibi engadinga ukunakekelwa kwezokwelapha.

Izimpawu zokweqisa zingase zihlanganise umlomo owomile kakhulu, ubunzima bokugwinya, umbono ongacacile, ukushaya kwenhliziyo okusheshayo, umkhuhlane, noma ukudideka. Ezimweni ezinzima, ungase uhlangabezane nobunzima bokuphefumula noma ukulahlekelwa ukwazi.

Ungazami ukuzenza uhlanze noma uthathe eminye imithi ukuze ulwe nokweqisa. Thola usizo lwezokwelapha ngokushesha, futhi ulethe ibhodlela lomuthi nawe ukuze abahlinzeki bezempilo bazi kahle ukuthi yini nokuthi ungakanani oyithathile.

Ngingenzani uma ngiphuthelwa umthamo we-Tolterodine?

Uma uphuthelwa umthamo we-tolterodine, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Uma kunjalo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungandisa ingozi yakho yemiphumela emibi. Uma uthatha inguqulo yokukhishwa okweluliwe futhi uphuthelwa umthamo, umthetho ofanayo uyasebenza - vele uthathe umthamo wakho olandelayo ngesikhathi esijwayelekile.

Uma uvame ukukhohlwa imithamo, zama ukusetha i-alamu yefoni noma usebenzise umhleli wamaphilisi. Ukuthatha imithi yakho ngokuqhubekayo kubalulekile ekulawuleni izimpawu eziqhubekayo.

Ngingayeka nini ukuthatha i-Tolterodine?

Ungayeka ukuthatha i-tolterodine lapho udokotela wakho enquma ukuthi kufanelekile, okuvame ukwenzeka lapho izimpawu zakho zilawulwa kahle noma uma uhlangabezana nemiphumela emibi edlula izinzuzo.

Ngokungafani neminye imithi, awudingi ukunciphisa kancane umthamo wakho we-tolterodine - ungaqeda ukuyithatha ngokuphazima kweso ngaphandle kwezimpawu zokuhoxisa. Kodwa-ke, izimpawu zakho ze-bladder esebenza ngokweqile cishe zizobuya phakathi nezinsuku ezimbalwa kuya evikini.

Abanye abantu bathatha amakhefu ngezikhathi ezithile ku-tolterodine ukuze babone ukuthi izimpawu zabo zithuthukile ngokwemvelo yini. Udokotela wakho angase asikisele le ndlela, ikakhulukazi uma ubelokhu uthatha umuthi isikhathi eside futhi izimpawu zakho zibonakala zizinzile.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Tolterodine?

Ungaba namanani amancane otshwala ngenkathi uthatha i-tolterodine, kodwa qaphela ukuthi kokubili utshwala ne-tolterodine kungabangela isiyezi nobuthongo. Uma kuhlanganiswe, le miphumela ingase ivele kakhulu.

Utshwala bungase futhi lucasule isinye sakho futhi lungase luqhubeke lukhulise izimpawu ze-bladder esebenza ngokweqile, okungase kuphikisane nezinye zezinzuzo ozitholayo ku-tolterodine.

Uma ukhetha ukuphuza utshwala, qala ngamanani amancane ukuze ubone ukuthi umzimba wakho usabela kanjani. Gwema ukushayela noma ukusebenzisa imishini uma uzizwa unesiyezi noma ulele kunokujwayelekile.