Yini i-Tranylcypromine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Tranylcypromine iyisidakamizwa esibhalwe ngudokotela esilwa nokucindezeleka esingaphansi kohlobo lwemithi ebizwa ngokuthi ama-monoamine oxidase inhibitors (MAOIs). Isetshenziselwa ikakhulukazi ukwelapha ukucindezeleka okukhulu lapho ezinye izidakamizwa ezilwa nokucindezeleka zingasebenzi kahle. Lo muthi usebenza ngokuvimba i-enzyme ebuchosheni bakho ehlukanisa amakhemikhali athile alawula imizwa, okusiza ukubuyisela ibhalansi nokuthuthukisa inhlalakahle yakho engokomzwelo.

Yini i-Tranylcypromine?

I-Tranylcypromine iyisidakamizwa esinamandla esilwa nokucindezeleka odokotela abasigcinela amacala lapho ezinye izindlela zokwelapha zingazange zinikeze impumuzo. Ithathwa njengenye yezidakamizwa ezinamandla zokulwa nokucindezeleka ezitholakalayo futhi idinga ukuqashwa ngokucophelela ngenxa yemiphumela yayo enamandla. Umuthi uza ngesimo samaphilisi futhi uthathwa ngomlomo, ngokuvamile ngaphansi kokuqashwa kwezokwelapha okuseduze.

Lo muthi ubelokhu usiza abantu abanokucindezeleka okukhulu amashumi eminyaka, nakuba ngokuvamile kungewona umuthi wokuqala ngenxa yokudla okuthile kanye nezidingo zokuxhumana kwezidakamizwa. Udokotela wakho cishe uzocabangela lo muthi uma uzamile ezinye izidakamizwa ezilwa nokucindezeleka ngaphandle kwempumelelo, njengoba kungasebenza kahle ekwelapheni ukucindezeleka okumelana nokwelashwa.

Isetshenziselwani i-Tranylcypromine?

I-Tranylcypromine ikakhulukazi ibhalelwe ukucindezeleka okukhulu, ikakhulukazi lapho ezinye izidakamizwa ezilwa nokucindezeleka zingasebenzi kahle kuwe. Ilusizo ikakhulukazi kubantu abahlangabezana nalokho odokotela abakubiza ngokuthi “ukucindezeleka okumelana nokwelashwa,” lapho imithi eminingi eye yanqanyulwa ngaphandle kwempumelelo.

Ngezinye izikhathi odokotela bangase futhi babhale i-tranylcypromine ezinye izimo, nakuba lokhu kuvamile. Lokhu kungabandakanya izifo ezithile zokukhathazeka noma ukucindezeleka okungajwayelekile, lapho ungase uhlangabezane nezimpawu ezinjengokwanda kwesifiso sokudla, ukulala ngokweqile, noma ukuzizwa ubucayi ngokweqile ekwenqabeni. Udokotela wakho uzonquma ukuthi lo muthi ulungele isimo sakho esithile.

Isebenza Kanjani I-Tranylcypromine?

I-Tranylcypromine isebenza ngokuvimba i-enzyme ebizwa nge-monoamine oxidase, evame ukwehlisa amakhemikhali abalulekile emizweni ebuchosheni bakho. Uma le enzyme ivinjelwe, amazinga e-serotonin, i-norepinephrine, kanye ne-dopamine ayanda, okusiza ukuphakamisa umoya wakho futhi kunciphise izimpawu zokucindezeleka.

Lo muthi uthathwa njengomqina kakhulu uma uqhathaniswa neminye imithi yokucindezeleka. Ngenkathi imithi emisha yokucindezeleka efana ne-SSRIs isebenza ngokukhethekile, i-tranylcypromine ithinta amakhemikhali amaningi obuchopho ngasikhathi sinye. Lesi senzo esibanzi singenza sisebenze kahle ekucindezelekeni okukhulu, kodwa futhi kusho ukuthi uzodinga ukulandela imihlahlandlela ethile yokudla futhi uqaphele ngokusebenzisana kwemithi.

Kufanele Ngiyithathe Kanjani I-Tranylcypromine?

Thatha i-tranylcypromine ngendlela eqondile udokotela wakho ayiyalayo, ngokuvamile kanye noma kabili ngosuku ngaphandle kokudla. Ungayithatha ngamanzi, ubisi, noma ijusi, nakuba abanye abantu bethola ukuthi ukuyithatha ngokudla kusiza ukunciphisa isisu esibuhlungu. Kungcono ukuyithatha ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo ohlelweni lwakho.

Udokotela wakho cishe uzoqala ngomthamo ophansi futhi awunyuse kancane kancane ngokusekelwe endleleni ozosabela ngayo. Ungagayi, ungaphi, noma uhlafune amaphilisi ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze kanjalo. Uma uhlangabezana nokucasuka kwesisu, ukuthatha umuthi ngokudla okulula noma ukudla okulula kungasiza ukunciphisa lokhu kungakhululeki.

Ngesikhathi sokwelashwa, uzodinga ukulandela ukudla okukhethekile okugwema ukudla okunama-tyramine amaningi, njengoshizi omdala, inyama eqediwe, nokudla okubilisiwe. Udokotela wakho noma usokhemisi uzokunikeza uhlu oluningiliziwe lokudla okufanele ukugweme, njengoba ukuhlanganisa lokhu kudla ne-tranylcypromine kungabangela ukwanda okuyingozi kwengcindezi yegazi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Tranylcypromine?

Ubude bokwelashwa nge-tranylcypromine buhlukahluka kakhulu kumuntu nomuntu, kodwa abantu abaningi badinga ukuyithatha izinyanga eziningana kuya eminyakeni. Udokotela wakho ngokuvamile uzofuna ukuthi uqhubeke nokuyithatha okungenani izinyanga eziyi-6 kuya kweziyi-12 ngemuva kokuthi izimpawu zakho zokucindezeleka zithuthuke ukuze usize ukuvimbela ukuphindeka.

Abanye abantu bangase badinge ukwelashwa isikhathi eside, ikakhulukazi uma beke baba neziqephu eziningi zokucindezeleka noma uma ukucindezeleka kwabo kubi kakhulu. Udokotela wakho uzobuyekeza njalo inqubekela phambili yakho futhi alungise uhlelo lwakho lokwelapha ngokufanele. Ungayeki ukuthatha i-tranylcypromine ngokuzumayo, ngoba lokhu kungabangela izimpawu zokuhoxisa kanye nezinguquko eziyingozi ezingase zibe khona ekucindezelweni kwegazi.

Yiziphi Imiphumela Eceleni ye-Tranylcypromine?

Njengayo yonke imithi, i-tranylcypromine ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi okulindeleke kungakusiza ukuthi uzizwe ulungiswe kangcono futhi wazi ukuthi ungaxhumana nini nodokotela wakho.

Imiphumela emibi evamile abantu abaningi abayitholayo ihlanganisa:

• Isiyezi noma ukukhathala, ikakhulukazi uma usukuma
• Umlomo owomile
• Ukuqunjelwa
• Ubunzima bokulala noma izinguquko emaphethini okulala
• Ukucindezeleka
• Isicanucanu noma isisu esibuhlungu
• Ukukhathala noma ukuzizwa ukhathele ngokungavamile
• Ushintsho ekudleni

Le miphumela emibi evamile ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi, ngokuvamile phakathi namasonto ambalwa okuqala okwelashwa.

Imiphumela emibi engathi sína idinga ukunakekelwa kwezokwelapha ngokushesha futhi ihlanganisa:

• Ukucindezeleka okukhulu nentamo eqinile
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ubuhlungu besifuba
• Ukucindezelwa kwegazi eliphezulu eliqhamukayo
• Isicanucanu esibi kakhulu nokuhlanza
• Ukudideka noma ukucasuka
• Ukuqina kwemisipha noma ukuthuthumela
• Umkhuhlane nokujuluka

Uma uhlangabezana nanoma yiziphi lezi zimpawu ezingathi sína, funa usizo lwezokwelapha ngokushesha, njengoba zingabonisa ukusabela okuyingozi.

Imiphumela emibi engavamile kodwa ebucayi nayo ingenzeka, okuhlanganisa izinkinga zesibindi, ukungezwani komzimba okukhulu, noma i-serotonin syndrome uma ihlanganiswe neminye imithi ethile. Udokotela wakho uzokuqapha ngokucophelela ukuze abone lezi zinkinga ngokuhlolwa okuvamile kanye nokuhlolwa kwegazi.

Ubani Ongafanele Athole I-Tranylcypromine?

I-Tranylcypromine ayifanele wonke umuntu, futhi izimo ezithile zezokwelapha noma izimo zikwenza kungaphephile ukuyisebenzisa. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela lo muthi.

Akufanele uthathe i-tranylcypromine uma une:

• Isifo sesibindi noma ama-enzyme esibindi aphakeme
• Isifo senhliziyo noma umlando wokuhlaselwa yinhliziyo
• Umfutho wegazi ophezulu ongaphathwanga kahle
• Umlando wokushaywa unhlangothi
• Isifo sezinso
• Umdlavuza wobuchopho noma ukulimala ekhanda
• I-Bipolar disorder (ngaphandle kwama-mood stabilizers)

Ngaphezu kwalokho, lo muthi ungasebenzisana ngendlela eyingozi neminye imithi eminingi, ngakho-ke uzodinga ukwazisa udokotela wakho ngayo yonke imithi, izithasiselo, kanye nemithi yezitshalo oyithathayo.

Abesifazane abakhulelwe nabancelisayo ngokuvamile kufanele bagweme i-tranylcypromine ngaphandle kwalapho izinzuzo zizwela ngokusobala izingozi. Uma uhlela ukukhulelwa noma uncelisa, xoxa ngezinketho zokwelashwa ezingezinye nodokotela wakho.

Amagama Omkhiqizo we-Tranylcypromine

I-Tranylcypromine itholakala ngaphansi kwegama lomkhiqizo elithi Parnate, okuyindlela evame kakhulu yokuyala lo muthi. Ungase futhi uyibone ibizwa ngegama layo elivamile, i-tranylcypromine sulfate, ebhodleleni lakho lemithi.

Amanye amakhemisi angase abe nezinhlobo ezahlukene ze-tranylcypromine ezivamile, kodwa zonke ziqukethe isithako esifanayo esisebenzayo. Uma ikhemisi lakho likushintshela kwenye inguqulo yomkhiqizo noma ejwayelekile, imiphumela kufanele ifane, nakuba kufanele uhlale uhlola nomuthi wakho uma unokukhathazeka nganoma yiziphi izinguquko emithini yakho.

Ezinye Izindlela Zokwelapha ze-Tranylcypromine

Uma i-tranylcypromine ingakulungele, kukhona ezinye izindlela zokwelapha ukucindezeleka. Udokotela wakho angase acabangele ezinye izidambisi zokucindezeleka ezinjenge-SSRIs (njenge-sertraline noma i-fluoxetine), ama-SNRIs (njenge-venlafaxine), noma ama-tricyclic antidepressants.

Ukwelashwa kokucindezeleka okungamelani nokwelashwa, ezinye izinketho zihlanganisa i-electroconvulsive therapy (ECT), i-transcranial magnetic stimulation (TMS), noma imithi emisha efana ne-esketamine nasal spray. Abanye abantu futhi bayazuza ekuhlanganiseni imithi ne-psychotherapy, njenge-cognitive behavioral therapy noma i-interpersonal therapy.

Enye indlela engcono kakhulu incike ezimpawini zakho ezithile, umlando wezokwelapha, nokuthi usabele kanjani ekwelashweni kwangaphambilini. Udokotela wakho uzosebenza nawe ukuthola inketho esebenza kahle kakhulu futhi ephephile esimweni sakho.

Ingabe i-Tranylcypromine Ingcono Kunezinye Izidambisi Zokucindezeleka?

I-Tranylcypromine akudingeki ukuthi ibe ngcono kunezinye izidambisi zokucindezeleka, kodwa ingasebenza kahle kakhulu kwabanye abantu, ikakhulukazi labo abanokucindezeleka okungamelani nokwelashwa. Ngenkathi izidambisi zokucindezeleka ezintsha njenge-SSRIs zivame ukuzanywa kuqala ngoba ngokuvamile ziphephe kakhulu futhi zinezithiyo ezimbalwa zokudla, i-tranylcypromine ingaba inketho ebalulekile lapho ezinye izindlela zokwelapha zingasebenzi.

Inzuzo enkulu ye-tranylcypromine ukusebenza kwayo ezimweni lapho ezinye izidambisi zokucindezeleka ziye zahluleka. Kodwa-ke, idinga ukuqapha okucophelelayo nokulungiswa kwendlela yokuphila kunezidakamizwa ezintsha. Udokotela wakho uzocabangela izici ezinjengobunzima bokucindezeleka kwakho, izimpendulo zokwelashwa kwangaphambilini, kanye nekhono lokulandela imikhawulo yokudla lapho enquma ukuthi i-tranylcypromine iyona engcono kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Tranylcypromine

Q1. Ingabe i-Tranylcypromine iphephile kubantu abanezifo zenhliziyo?

I-Tranylcypromine ingaba yingozi kubantu abanezifo zenhliziyo ngoba ingathinta umfutho wegazi nesigqi senhliziyo. Uma unesinye isimo senhliziyo, udokotela wakho uzodinga ukuhlola ngokucophelela ukuthi izinzuzo zidlula yini izingozi. Bangase badinge ukuqapha okwengeziwe, okuhlanganisa ukuhlolwa njalo komfutho wegazi nokuqapha isigqi senhliziyo, uma benquma ukuthi umuthi udingeka ekwelapheni kwakho ukucindezeleka.

Q2. Kufanele Ngenzeni Uma Ngithatha I-Tranylcypromine Ngengozi Ngokweqile?

Uma ngengozi uthatha i-tranylcypromine ngokweqile, funa usizo oluphuthumayo lwezokwelapha ngokushesha. Izimpawu zokweqisa zingahlanganisa ikhanda elibuhlungu elibuhlungu, ubuhlungu besifuba, ukushaya kwenhliziyo okusheshayo, umkhuhlane ophezulu, ukudideka, noma ukulahlekelwa ukwazi. Ungalindi ukubona ukuthi izimpawu ziyavela yini - shayela ku-911 noma uye egumbini eliphuthumayo eliseduze ngokushesha. Letha ibhodlela lakho lomuthi nawe ukuze abasebenzi bezokwelapha bakwazi ukubona kahle ukuthi uthathe ini nokuthi uthathe kangakanani.

Q3. Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Tranylcypromine?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze nesikhathi somthamo wakho olandelayo. Kulokho, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile. Ungalokothi uthathe umthamo ophindwe kabili ukuze ulungise okungaphuthelwanga, ngoba lokhu kungaba yingozi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi ukukusiza ukuthi uhlale emgqeni.

Q4. Ngingayeka Nini Ukuthatha I-Tranylcypromine?

Ungalokothi uyeke ukuthatha i-tranylcypromine ngokuzumayo, ngoba lokhu kungabangela izimpawu eziyingozi zokuhoxisa kanye nokubuyela ngokushesha kokucindezeleka. Udokotela wakho uzokwenza isimiso sokunciphisa kancane kancane, anciphise kancane umthamo wakho emasontweni amaningana noma izinyanga. Isikhathi sincike ekutheni usuthatha isikhathi esingakanani umuthi, umthamo wakho wamanje, nokuthi ukucindezeleka kwakho kulawulwa kahle kangakanani. Njalo sebenzisana nodokotela wakho ukuhlela noma yiziphi izinguquko emuthini wakho.

Q5. Ngingakwazi Yini Ukuphuza Utshwala Ngenkathi Ngithatha I-Tranylcypromine?

Kufanele ukugweme utshwala ngenkathi uthatha i-tranylcypromine, ngoba kungakhuphula ingozi yemiphumela emibi, okuhlanganisa ukwehla okukhulu kwengcindezi yegazi. Utshwala bungase futhi buqhubeke nemiphumela yokucindezeleka futhi buphazamise ukusebenza kahle komuthi. Uma ulwa nokusebenzisa utshwala, yiba qotho nodokotela wakho ukuze bakusize ukuthi uthole izinsiza ezifanele nokusekelwa ngenkathi uphatha ukwelashwa kwakho kokucindezeleka.