Yini i-Trazodone: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Trazodone iyimithi yokucindezeleka odokotela abayibhala njalo ukusiza abantu ukuthi balale kangcono. Ekuqaleni yathuthukiswa ukwelapha ukucindezeleka, le mithi isebenza ngokulinganisa amakhemikhali athile ebuchosheni bakho athinta imizwa namaphethini okulala.

Ungase uzibuze ukuthi i-trazodone ilungile yini esimweni sakho. Le mithi emnene isize izigidi zabantu ukulawula ukucindezeleka nezinkinga zokulala, futhi ukuqonda ukuthi isebenza kanjani kungakusiza ukuthi ube nezingxoxo ezingcono nomhlinzeki wakho wezempilo mayelana nezinketho zakho zokwelashwa.

Yini i-Trazodone?

I-Trazodone ingeyeqembu lemithi ebizwa ngokuthi ama-serotonin modulators. Yahlukile kweminye imithi eminingi yokucindezeleka ngoba isebenza kumakhemikhali obuchopho amaningi ngesikhathi esisodwa, yingakho ingasiza kokubili imizwa nokulala.

Le mithi yaqala ukugunyazwa yi-FDA ngo-1981 ukwelapha ukucindezeleka. Eminyakeni edlule, odokotela bathola ukuthi imiphumela ye-trazodone yokuthulisa yayenza ilungele ikakhulukazi abantu abahlushwa yi-insomnia, ngisho nasemithini ephansi kunezo ezisetshenziselwa ukucindezeleka.

Okuhlukile nge-trazodone ukusebenza kwayo okumbili. Akugcini nje ukusiza ukuphakamisa imizwa yakho ngokuhamba kwesikhathi kodwa futhi kungakusiza ukuthi ulale kalula ebusuku obuyithathayo.

Isetshenziselwani i-Trazodone?

I-Trazodone iphatha i-major depressive disorder njengokusetshenziswa kwayo okuyinhloko. Kodwa-ke, odokotela bavame ukuyibhala ngezinkinga zokulala, ikakhulukazi lapho eminye imithi yokulala ingasebenzi kahle noma ingafaneleki ukusetshenziswa isikhathi eside.

Nawa amakhondishini amakhulu i-trazodone engasiza ngawo, futhi ungase ukuthole kuqinisekisa ukwazi ukuthi udokotela wakho uzocabangela ngokucophelela ukuthi yikuphi ukusetshenziswa okufanele kakhulu esimweni sakho esithile:

• Ukuphazamiseka okukhulu kwengqondo nokudabuka okuqhubekayo
• Ukuqwasha nobunzima bokulala
• Izinkinga zokulala (ukuvuka kaningi ebusuku)
• Izifo zokukhathazeka, ngezinye izikhathi njengokwelashwa okwengeziwe
• Izimo zobuhlungu ezingapheli eziphazamisa ukulala

Abanye odokotela baphinda banikeze i-trazodone ngezimo ezingavamile njengokuphazamiseka kwengqondo okubangelwa ukuhlukumezeka (i-PTSD) lapho ukuphazamiseka kokulala kuyinkinga enkulu. Umhlinzeki wakho wezempilo uzonquma indlela engcono kakhulu esekelwe ezidingweni zakho ngazinye nomlando wakho wezokwelapha.

Isebenza Kanjani I-Trazodone?

I-Trazodone isebenza ngokuthinta i-serotonin, ikhemikhali yobuchopho ethonya kokubili imizwa nokulala. Ngokungafani neminye imithi eqinile, i-trazodone ithathwa njenge-antidepressant enamandla aphakathi nendawo elungisa ngobumnene amakhemikhali akho obuchopho ngokuhamba kwesikhathi.

Ngokucindezeleka, i-trazodone yandisa inani le-serotonin elitholakala ebuchosheni bakho ngokuvimba ukuthathwa kwayo kabusha. Le nqubo ivame ukuthatha amasonto amaningana ukukhombisa imiphumela ephelele, okujwayelekile ngokuphelele emithini ye-antidepressant.

Uma kuziwa ekulaleni, i-trazodone isebenza ngendlela ehlukile. Ivimba ama-receptors athile ebuchosheni bakho akugcina uqaphile, idale umphumela ozolile, olalisa. Lesi senzo esithuthukisa ukulala senzeka kungakapheli imizuzu engama-30 kuya kwengama-60 ngemva kokuthatha umuthi, ngokungafani nezinzuzo zemizwa ezithuthuka kancane kancane.

Umuthi uthambile kunezinsiza eziningi zokulala ngoba awuphoqi ubuchopho bakho ukuba bungene esimweni sokulala esingajwayelekile. Kunalokho, kusiza ukususa ezinye zezithiyo ezingase zikugcine uvukile.

Kufanele Ngiyithathe Kanjani I-Trazodone?

Thatha i-trazodone ngendlela eqondile udokotela wakho ayiyalayo, futhi cishe uzothola ukuthi isebenza kahle uma ulandela isimiso esiqhubekayo. Abantu abaningi bayayithatha nokudla ukuze kuncishiswe isisu esicasulayo futhi kuthuthukiswe ukumuncwa.

Uma uthatha i-trazodone ukuze ulale, udokotela wakho cishe uzokuncoma ukuyithatha cishe imizuzu engama-30 ngaphambi kokulala. Ukuba nesnakhi esilula ngayo kungasiza ekuvikeleni isicanucanu futhi kwenze imithi isebenze kangcono.

Ukuze welashwe ukucindezeleka, ungase uthathe i-trazodone kanye ngosuku ngesikhathi sokulala noma uyihlukanise ibe yizilinganiso ezincane usuku lonke. Udokotela wakho uzoqala ngomthamo ophansi futhi awunyuse kancane kancane ngokusekelwe endleleni ozosabela ngayo.

Nawa amathiphu awusizo angakusiza ukuthi uthole inzuzo enkulu ku-trazodone:

• Yithathe ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo ohlelweni lwakho
• Gwema utshwala, obungandisa ukozela nemiphumela emibi
• Ungagxobi noma uhlafune amaphilisi akhishwe isikhathi eside
• Gcina ingilazi yamanzi eduze uma uzizwa unesiyezi lapho umile
• Dala umkhuba wokulala okhululekile uma uyisebenzisela ukulala

Khumbula ukuthi kujwayelekile ngokuphelele ukuzwa ukozela ngakusasa ekuseni uma uqala ukuthatha i-trazodone. Lo mphumela uvame ukuthuthuka njengoba umzimba wakho ujwayela imithi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Trazodone?

Ubude bokwelashwa nge-trazodone buxhomeke ekutheni uyithathelani nokuthi isebenza kahle kangakanani kuwe. Ngokucindezeleka, abantu abaningi badinga ukuyithatha okungenani izinyanga eziyisithupha kuya ngonyaka ngemuva kokuthi izimpawu zabo zithuthuke.

Uma usebenzisa i-trazodone ikakhulukazi ukulala, udokotela wakho angase ancome ukusetshenziswa kwesikhathi esifushane noma amakhefu ngezikhathi ezithile ukuze abone ukuthi amaphethini akho okulala emvelo athuthukile yini. Abanye abantu bathola ukuthi banganciphisa umthamo wabo ngokuhamba kwesikhathi noma bawuthathe kuphela uma kudingeka.

Umhlinzeki wakho wezempilo uzosebenza nawe ukuze athole ubude obufanele. Bazocabangela izici ezinjengempendulo yakho ekwelashweni, noma yimiphi imiphumela emibi oyitholayo, kanye nemigomo yakho yonke yezempilo.

Ungayeki ukuthatha i-trazodone ngokuzumayo, ikakhulukazi uma ubuthatha ngenxa yokucindezeleka. Udokotela wakho uzokusiza ukuthi unciphise umthamo kancane kancane ukuze uvimbele izimpawu zokuhoxisa njengokugajezwa, isicanucanu, noma izinguquko zemizwa.

Yiziphi Izimo Ezingezinhle Ze-Trazodone?

Abantu abaningi bayayibekezelela i-trazodone kahle, kodwa njengayo yonke imithi, ingabangela imiphumela emibi. Izindaba ezinhle ukuthi imiphumela eminingi emibi imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Ake sibheke imiphumela emibi evame kakhulu ongase uyithole, sikhumbula ukuthi akubona bonke abantu abazoba nayo futhi ngokuvamile bayalawuleka:

• Ukozela nokukhathala (ikakhulukazi emasontweni ambalwa okuqala)
• Ukugajezwa lapho usukuma ngokushesha
• Umlomo owomile nokwanda komzwelo wokoma
• Isicanucanu noma isisu esibuhlungu
• Ikhanda elibuhlungu
• Ukubona okungacacile
• Ukuqunjelwa

Abanye abantu futhi bathola imiphumela emibi engavamile njengamaphupho acacile, izinhlungu zemisipha, noma izinguquko ekudleni. Le miphumela ngokuvamile imnene futhi yesikhashana.

Nakuba kungavamile, kunezinye izimo ezingezinhle ezingathi sína ezidinga ukunakekelwa kwezempilo ngokushesha, nakuba kubalulekile ukungakhathazeki ngokweqile ngalezi zinto ezingenzeka:

• Ukuvuka okubuhlungu okuqhubekayo emadodeni (i-priapism)
• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Ukugajezwa okukhulu noma ukuquleka
• Izimpawu ze-serotonin syndrome (umkhuhlane, ukudideka, ukushaya kwenhliziyo okusheshayo)
• Ukuphuma kwegazi okungajwayelekile noma ukulimala
• Imicabango yokuzilimaza (ikakhulukazi kubantu abadala abasebancane)

Uma uthola noma yiziphi izimpawu ezikhathazayo, xhumana nomhlinzeki wakho wezempilo ngokushesha. Bangasiza ekutholeni ukuthi ngabe izimpawu zihlobene ne-trazodone futhi balungise ukwelashwa kwakho uma kudingeka.

Ubani Ongafanele Athatha I-Trazodone?

I-Trazodone ayifanele wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyibhala. Zikhona izimo ezithile lapho i-trazodone ingase ingabi yindlela engcono kuwe.

Kufanele ukugweme i-trazodone uma unenkinga yokungezwani nayo noma uma uthathe uhlobo lwe-antidepressant olubizwa nge-MAO inhibitor ezinsukwini eziyi-14 ezedlule. Udokotela wakho uzobuza ngayo yonke imithi yakho yamanje ukuze ahlole ukuthi akukho yini ukuxhumana okuyingozi.

Nawa amanye amakhambi adinga ukuqapha okukhethekile noma angase enze i-trazodone ingafaneleki, nakuba udokotela wakho engasiza ekunqumeni ukuthi yini ephephe kakhulu esimweni sakho esithile:

• Ukunqamuka kwenhliziyo kwakamuva noma izinkinga ezinkulu zesigqi senhliziyo
• Isifo esibi sesibindi noma sezinso
• Umlando we-priapism (ukuqina okuqhubekayo)
• I-Bipolar disorder (ngaphandle kokuthi iqashwe ngokucophelela)
• I-Angle-closure glaucoma
• Ukukhulelwa noma ukuncelisa

Uma unanoma yiziphi zalezi zimo, ungacabangi ukuthi i-trazodone ayivunyelwe ngokuphelele. Udokotela wakho angase akwazi ukuyinikeza ngokuqapha okwengeziwe noma ngomthamo olungisiwe uma izinzuzo zidlula izingozi.

Amagama e-Brand e-Trazodone

I-Trazodone itholakala ngaphansi kwamagama amaningi e-brand, nakuba inguqulo ejwayelekile isebenza kahle futhi ibiza kancane. Igama elivamile le-brand yi-Desyrel, okuyiyona fomula yokuqala.

Ungase futhi ubone izinguqulo ezikhishwe isikhathi eside njenge-Oleptro, eyenzelwe ukukhipha imithi kancane usuku lonke. Lokhu kungasiza kubantu abathatha i-trazodone ngenxa yokucindezeleka abafuna ukugwema imithamo eminingi yansuku zonke.

Noma ngabe uthatha i-trazodone ejwayelekile noma inguqulo yegama le-brand, isithako esisebenzayo siyafana. Umuthi wakho wemithi angakusiza ukuthi uqonde noma iyiphi imininingwane ehlukile phakathi kwezindlela zokwakheka futhi uqinisekise ukuthi uthola inketho eshibhile kakhulu.

Ezinye izindlela ze-Trazodone

Uma i-trazodone ingasebenzi kahle kuwe noma ibangela imiphumela engathandeki, kunezindlela eziningana ezingase zicatshangelwe udokotela wakho. Ukukhetha okungcono kuncike ekutheni welapha ukucindezeleka, izinkinga zokulala, noma zombili.

Ngeminyaka yokucindezeleka, ezinye izindlela zokulwa nokucindezeleka ezifana ne-sertraline (Zoloft), escitalopram (Lexapro), noma i-bupropion (Wellbutrin) zingase zibe izinketho ezingcono. Ngayinye isebenza ngendlela ehlukile futhi ineziphumo zayo.

Ngezinkinga zokulala, ezinye izindlela zihlanganisa:

• Izithasiselo ze-Melatonin zezinkinga zokulala ezilula
• I-Zolpidem (Ambien) ye-insomnia yesikhashana
• I-Mirtazapine, enye indlela yokulwa nokucindezeleka eneziphumo zokuthulisa
• Ukwelashwa kokuziphatha kokulala, okungase kusebenze kahle isikhathi eside
• I-Gabapentin kubantu abanezinhlungu ezingapheli ezithinta ukulala

Izindlela ezingezona zemithi ezifana ne-cognitive behavioral therapy for insomnia (CBT-I) zingase zisebenze kahle kakhulu futhi azinazo iziphumo ezihambisana nemithi. Udokotela wakho angakusiza ukuthi uhlole zonke izinketho zakho.

Ingabe i-Trazodone Ingcono Kune-Ambien?

I-Trazodone ne-Ambien (zolpidem) yomibili imithi yokulala esebenzayo, kodwa isebenza ngezindlela ezihlukene futhi inezinzuzo ezihlukene. Ukukhetha okungcono kuncike ezidingweni zakho ezithile kanye nomlando wezokwelapha.

I-Trazodone ngokuvamile ithathwa njengephephile ekusetshenzisweni kwesikhathi eside ngoba mancane amathuba okuthi idale ukuncika noma ukubekezelelana. Futhi ayibizi kakhulu njengoba itholakala njengemithi ejwayelekile.

I-Ambien ivame ukusebenza ngokushesha futhi ingase isebenze kahle kakhulu nge-insomnia enzima, kodwa ngokuvamile inconywa ukuthi isetshenziswe isikhathi esifushane kuphela. Ingase futhi idale ukuziphatha okuyinkimbinkimbi kokulala njengokuhamba ulele noma ukudla ulele ezimweni ezingavamile.

Nakhu ukuthi ziqhathaniswa kanjani ngokuqondile:

• I-Trazodone: Ingcono ekusetshenzisweni kwesikhathi eside, ayenzi umlutha, futhi iphatha ukucindezeleka
• I-Ambien: Isebenza ngokushesha, ingase isebenze kahle kakhulu nge-insomnia enzima, isikhathi esifushane
• I-Trazodone: Ingase idale ukozela ngosuku olulandelayo, ikakhulukazi ekuqaleni
• I-Ambien: Maningi amathuba okuthi ingabangeli ukukhathala ekuseni kodwa ingozi enkulu yokuncika

Udaktela wakho uzocabangela izinto ezinjengendlela yakho yokulala, ezinye izimo zempilo, kanye nemigomo yokwelashwa lapho enquma ukuthi imuphi umuthi ofaneleka kakhulu kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Trazodone

Q1. Ingabe i-Trazodone iphephile ezigulini ezinokuphathwa yisifo senhliziyo?

I-Trazodone ingaphepha kubantu abanezifo zenhliziyo, kodwa idinga ukuqashwa ngokucophelela ngudokotela wakho. Umuthi ngezinye izikhathi ungathinta ukushaya kwenhliziyo, ikakhulukazi ngemithamo ephezulu noma kubantu abanezimo zenhliziyo ezikhona.

Uma unesifo senhliziyo, udokotela wakho cishe uzoqala ngomthamo ophansi futhi aqaphe ukusebenza kwenhliziyo yakho ngokucophelela. Bangase bayale i-EKG ngaphambi kokuqala ukwelashwa futhi ngezikhathi ezithile ngenkathi uthatha umuthi.

Ingozi ngokuvamile iphansi kubantu abaningi, futhi abantu abaningi abanezifo zenhliziyo bathatha i-trazodone ngokuphepha. Udokotela wakho wenhliziyo nodokotela obhalayo kufanele basebenzisane ukuqinisekisa ukuthi yiyona ndlela efanele kuwe.

Q2. Kufanele ngenzeni uma ngiphuzile i-Trazodone eningi ngengozi?

Uma uthathe i-trazodone eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma uzizwa kahle. Ukuthatha okuningi kungabangela imiphumela emibi engathi sína efana nezinguquko eziyingozi ekushayeni kwenhliziyo noma ukulala ngokweqile.

Ungazami ukuzenza uhlanze noma uthathe eminye imithi ngaphandle uma uqondiswe ngqo ngumhlinzeki wezempilo. Uma uhlangabezana nezimpawu ezinzima njengobunzima bokuphefumula, ubuhlungu besifuba, noma ukulahlekelwa ukwazi, shayela u-911 ngokushesha.

Gcina ibhodlela lomuthi unawo lapho ufuna usizo ukuze ochwepheshe bezokwelapha bazi kahle ukuthi uthatheni ini nokuthi uthathe kangakanani. Ukweqisa kwe-trazodone okuningi kuyelapheka, ikakhulukazi ngokunakekelwa kwezokwelapha okusheshayo.

Q3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Trazodone?

Uma uphuthelwa umthamo we-trazodone, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuyisikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ongawuthathanga, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma uthatha i-trazodone ukuze ulale futhi uphuthelwa umthamo wakho wokulala, ngokuvamile kungcono ukuwushaya indiva kunokuwuthatha phakathi kwamabili.

Uma uvame ukukhohlwa imithamo, cabangela ukusetha i-alamu yansuku zonke noma usebenzise umhleli wamaphilisi. Isikhathi esiqhubekayo sisiza ukugcina amazinga aqhubekayo omuthi ohlelweni lwakho ukuze uthole imiphumela engcono kakhulu.

Q4. Ngingayeka nini ukuthatha i-Trazodone?

Kufanele uyeke kuphela ukuthatha i-trazodone ngaphansi kokuqondisa kukadokotela wakho, ikakhulukazi uma ubuthatha ukucindezeleka. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa njengokugajwa, isicanucanu, ikhanda elibuhlungu, noma izinguquko zemizwa.

Udokotela wakho ngokuvamile uzokwehlisa umthamo wakho kancane kancane phakathi namasonto amaningana noma izinyanga, kuye ngokuthi ubuthatha isikhathi esingakanani nokuthi umthamo wakho wamanje unjani. Le nqubo yokunciphisa isiza umzimba wakho ukuthi ulungise futhi inciphisa imiphumela yokuhoxisa.

Uma uthatha i-trazodone ikakhulukazi ukuze ulale, udokotela wakho angase ancome ukuzama ukuphumula ngezikhathi ezithile ukuze abone ukuthi amaphethini akho okulala emvelo athuthukile yini. Abanye abantu bathola ukuthi bangagcina beyekile noma behlisa umthamo wabo kakhulu.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Trazodone?

Kungcono ukugwema utshwala ngenkathi uthatha i-trazodone, njengoba le nhlanganisela ingaba yingozi. Zombili lezi zinto zingabangela ukozela futhi zithinte ukuxhumana kwakho, futhi uma zihlangene zingalimaza kakhulu ikhono lakho lokucabanga ngokucacile noma ukusabela ngokushesha.

Utshwala bungaphazamisa nokusebenza kwe-trazodone futhi bungase lenze izimpawu zokucindezeleka noma ukukhathazeka zibe zimbi. Uma ukhetha ukuphuza ngezikhathi ezithile, khuluma nodokotela wakho ngemikhawulo yesikhathi esiphephile.

Khumbula ukuthi utshwala bungaphazamisa ikhwalithi yokulala ngisho noma bungase bukwenze uzizwe ukozela ekuqaleni. Njengoba kungenzeka ukuthi uthatha i-trazodone ukuze uthuthukise ukulala kwakho noma imizwa yakho, utshwala bungase busebenze ngokumelene nemigomo yakho yokwelashwa.