Yini i-Varicella-Zoster Immune Globulin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Varicella-zoster immune globulin (VZIG) iyimithi evikelayo esiza ukuvimbela i-chickenpox kubantu abasengozini enkulu yezinkinga ezinzima. Yenziwe ngama-antibody anikelwe ngabantu abanokuzivikela okunamandla emzimbeni ngokumelene negciwane le-varicella-zoster, elibangela i-chickenpox kanye ne-shingles.

Le mithi isebenza njengesihlangu sesikhashana sesimiso sakho somzimba sokuzivikela. Uma wamukela i-VZIG, uthola ama-antibody alungile angalwa negciwane le-chickenpox uma uvezwa kulo. Cabanga ngakho njengokuboleka ukuzivikela komuntu omunye kuze kube yilapho umzimba wakho ungazivikela wona.

Isetshenziselwani i-Varicella-Zoster Immune Globulin?

I-VZIG isetshenziswa ikakhulukazi ukuvimbela i-chickenpox enzima kubantu abanezinhlelo ezibuthakathaka zokuzivikela noma ezinye izimo eziyingozi. Akuyona indlela yokwelapha i-chickenpox esiqalile kakade, kodwa kunalokho isinyathelo sokuvimbela esinikezwa ngemva kokuchayeka egciwaneni.

Udokotela wakho angase ancome i-VZIG uma uke wachayeka ku-chickenpox futhi ungena kwesinye sezigaba eziyingozi eziningi. Lokhu kufaka phakathi abantu abathola ukwelashwa komdlavuza, abamukeli bezitho, abesifazane abakhulelwe abangakaze babe ne-chickenpox, kanye nezingane ezisanda kuzalwa omama bazo abathuthukise i-chickenpox ngesikhathi sokubeletha.

Le mithi isetshenziswa futhi kubantu abathatha imithi ecindezela amasosha omzimba, njengama-steroid amaningi noma imithi ethile ye-arthritis. Abasebenzi bezempilo namalungu omndeni abasengozini enkulu futhi abaye bachayeka nabo bangase bathole lokhu kuvikelwa.

Isebenza kanjani i-Varicella-Zoster Immune Globulin?

I-VZIG iqukethe ama-antibody agxilile aqondise ngqo igciwane le-varicella-zoster. Uma ifakwe emsipheni wakho, la ma-antibody angena egazini lakho futhi anikeze ukuvikelwa okusheshayo, kwesikhashana ngokumelene ne-chickenpox.

Lokhu kuthathwa njengokwelashwa okuvimbela okuqinile okuphakathi nendawo. Ama-antibody anganciphisa ingozi yakho yokuthuthukisa i-chickenpox ngamaphesenti angama-85% uma inikezwa ngesikhathi esifanele. Uma usathola i-chickenpox naphezu kokuthola i-VZIG, lesi sifo sivame ukuba mnene kakhulu kunokuba besizoba ngaphandle kokuvikelwa.

Ukuvikelwa okuvela ku-VZIG kuhlala amasonto amathathu kuya kwamane. Ngesikhathi lesi, ama-antibody abolekiwe ancipha kancane emzimbeni wakho, yingakho ukuvikelwa kungokwesikhashana kunokuba kungokwaphakade njengoba umgomo unganikeza.

Ngingayithatha kanjani i-Varicella-Zoster Immune Globulin?

I-VZIG inikezwa njengomjovo emsipheni wakho, ngokuvamile engalweni yakho noma ethangeni. Umhlinzeki wezempilo uzohlala ekunikeza lo mjovo - awukwazi ukuwuthatha ekhaya. Indawo yokujova ingase izwe buhlungu usuku noma ezimbili ngemva kwalokho, okujwayelekile ngokuphelele.

Awudingi ukulungiselela lo mjovo ngokugwema ukudla noma iziphuzo. Ungadla ngokujwayelekile ngaphambi nangemva kokuthola i-VZIG. Nokho, yazisa umhlinzeki wakho wezempilo ngemithi oyithathayo, njengoba eminye imithi ingase ithinte ukuthi i-VZIG isebenza kahle kangakanani.

Isikhathi salo mjovo sibalulekile ukuze usebenze ngempumelelo. I-VZIG isebenza kahle kakhulu uma inikezwa kungakapheli amahora angama-96 (izinsuku ezi-4) ngemva kokuchayeka ku-chickenpox. Ngokushesha uma uyithola ngemva kokuchayeka, kungcono ukukuvikela.

Kufanele ngiyithathe isikhathi esingakanani i-Varicella-Zoster Immune Globulin?

I-VZIG ngokuvamile inikezwa njengomjovo owodwa, hhayi njengokwelashwa okuqhubekayo. Umthamo owodwa ngokuvamile unikeza ukuvikelwa amasonto amathathu kuya kwamane ngemva kokuthi uwutholile.

Kwezinye izimo ezingavamile, udokotela wakho angase ancome umthamo wesibili uma uchayeka kwenye i-chickenpox ngemva kokuthi umthamo wokuqala usuphelile. Lesi sinqumo sincike ezingozini zakho zomuntu ngamunye kanye nesimo somzimba wakho sokuzivikela.

Ukuvikelwa okuvela ku-VZIG akuhlali phakade, ngakho-ke uma usengozini ephezulu eqhubekayo, udokotela wakho angase axoxe ngamanye amaqhinga okuvimbela isikhathi eside nawe, njengomgomo we-chickenpox uma isimiso sakho somzimba singakwazi ukuwumelana.

Ziyini Imiphumela Eceleni ye-Varicella-Zoster Immune Globulin?

Abantu abaningi bayamukela kahle i-VZIG, ngemiphumela emincane kuphela eceleni eziphela yodwa. Imiphumela ejwayelekile eceleni yenzeka ngqo endaweni yokujova futhi ivamise ukulawuleka.

Nansi imiphumela eceleni ongase uyithole, uqala ngalezo ezivamile kakhulu:

• Ubuhlungu, ububomvu, noma ukuvuvukala endaweni yokujova
• Umkhuhlane omncane noma ukuzizwa ungaphilile kancane
• Ikhanda
• Ukulimala kwemisipha
• Isicanucanu noma isisu esibuhlungu
• Isiyezi
• Ukuqubuka kwesikhumba (ngokuvamile okulula)

Le miphumela ejwayelekile eceleni ngokuvamile iyaphela ezinsukwini ezimbalwa futhi ayidingi ukwelashwa okukhethekile ngaphandle kokuphumula nezinyathelo zokunethezeka.

Nakuba kungavamile, abanye abantu bangase babe nemiphumela eceleni engathi sína edinga ukunakekelwa kwezokwelapha. Lezi zimo ezingavamile zihlanganisa ukusabela okukhulu komzimba okunzima ngokuphefumula okunzima, ukuqina kwesifuba, noma ukuqubuka okubanzi. Izinkinga zokujiya kwegazi ziye zabikwa ngezikhathi ezithile, ikakhulukazi kubantu asebenobungozi bokujiya kwegazi.

Uma uhlangabezana nanoma yiziphi izimpawu ezinzima ngemuva kokuthola i-VZIG, xhumana nomhlinzeki wakho wezempilo ngokushesha noma funa ukunakekelwa kwezimo eziphuthumayo uma izimpawu zinzima.

Ubani Ongafanele Athole i-Varicella-Zoster Immune Globulin?

I-VZIG ayifanele wonke umuntu, futhi udokotela wakho uzocabangela ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyincoma. Abantu abanezimo ezithile noma izimo kungenzeka bangabi ngabantu abafanelekayo kulokhu kwelashwa.

Akufanele uthole i-VZIG uma uke waba nokusabela okukhulu komzimba ezintweni ze-immune globulin esikhathini esidlule. Abantu abanokuntuleka kwe-immunoglobulin A (IgA) bangase futhi badinge ukugwema i-VZIG, njengoba bengase babe nokusabela okukhulu komzimba.

Udktela wakho uzophinda aqaphele ukukunika i-VZIG uma unezifo ezithile zokujiya kwegazi noma usesengozini enkulu yamaqhubu egazi. Lokhu kuhlanganisa abantu abanomlando wokushaywa unhlangothi, ukuhlaselwa yinhliziyo, noma amaqhubu egazi emilenzeni noma emaphashini.

Uma ukhulelwe, udokotela wakho uzohlola ngokucophelela izinzuzo nezingozi. Ngenkathi i-VZIG inganikezwa ngesikhathi sokukhulelwa lapho izinzuzo zidlula izingozi, idinga ukugadwa ngokucophelela kwezokwelapha.

Amagama Omkhiqizo we-Varicella-Zoster Immune Globulin

I-VZIG iyatholakala ngaphansi kwegama lomkhiqizo elithi VariZIG e-United States. Lolu uhlobo olusetshenziswa kakhulu lwe-varicella-zoster immune globulin emithini.

Umhlinzeki wakho wezempilo uzokwazi ukuthi yimuphi umkhiqizo otholakala endaweni yakho. Okubalulekile ukuthi uthola ukwelashwa ngokushesha ngemuva kokuchayeka, kungakhathaliseki igama lomkhiqizo elithile.

Ezinye Izindlela ze-Varicella-Zoster Immune Globulin

Uma i-VZIG ingatholakali noma ingafaneleki kuwe, udokotela wakho angase acabange ezinye izinketho zokusiza ukuvimbela izinkinga ze-chickenpox. Ukukhetha kuncike esimweni sakho esithile kanye nezici eziyingozi.

Umuthi wokugoma i-chickenpox (umuthi wokugoma i-varicella) ungenye indlela yabanye abantu, kodwa ayifanele labo abanezinhlelo zokuzivikela ezibuthakathaka kakhulu. Umuthi wokugoma usebenza ngendlela ehlukile kune-VZIG - usiza umzimba wakho ukuthi wakhe ukuzivikela kwawo kunokuhlinzeka ngama-antibody okwesikhashana.

Imithi elwa namagciwane efana ne-acyclovir ingase isetshenziswe kwezinye izimo, ikakhulukazi uma uthola i-chickenpox naphezu kwezinyathelo zokuvimbela. Le mithi ingasiza ekunciphiseni ubukhulu nobude besifo uma iqala ngokushesha.

Kwabanye abantu abasengozini enkulu, ukwelashwa okuvamile kwe-intravenous immune globulin (IVIG) kungase kunikeze ukuvikelwa okuthile, nakuba lokhu kungaqondile njenge-VZIG.

Ingabe i-Varicella-Zoster Immune Globulin Ingcono Kune-Chickenpox Vaccine?

I-VZIG nomuthi wokugoma i-chickenpox basebenzela izinhloso ezehlukene, ngakho ukuqhathanisa kubalulekile ngokuya ngesimo sakho esithile. I-VZIG inikeza ukuvikeleka ngokushesha kodwa okwesikhashana, kanti umuthi wokugoma wakha ukuzivikela isikhathi eside.

Uma usuvele wavezwa yi-chickenpox, i-VZIG iyindlela engcono kuwe ngoba isebenza ngokushesha. Umuthi wokugoma uthatha isikhathi ukwakha ukuzivikela futhi ngeke usize uma usuvele wavezwa yileli gciwane.

Ukuvimbela isikhathi eside, umuthi wokugoma i-chickenpox ngokuvamile ukhethwa kubantu abanezinhlelo zokuzivikela ezisempilweni. Inikeza ukuvikeleka okuhlala isikhathi eside futhi ishibhile ngokuhamba kwesikhathi. Kodwa-ke, uma uhlelo lwakho lokuzivikela selulimele, i-VZIG ingase ibe yindlela yakho kuphela ephephile.

Udokotela wakho uzokusiza ukuthi uqonde ukuthi iyiphi inketho engcono kakhulu ezimweni zakho ezithile kanye nesimo sempilo.

Imibuzo Evame Ukubuzwa Nge-Varicella-Zoster Immune Globulin

Ingabe i-Varicella-Zoster Immune Globulin iphephile kwabesifazane abakhulelwe?

Yebo, i-VZIG ingaphepha kwabesifazane abakhulelwe lapho izinzuzo zidlula izingozi. Abesifazane abakhulelwe abangakaze babe ne-chickenpox futhi bavezwa yileli gciwane basengozini yezinkinga ezinzima, okuhlanganisa i-pneumonia kanye nezinkinga ezingathinta ingane.

Udokotela wakho uzohlola ngokucophelela isimo sakho uma ukhulelwe futhi wavezwa yi-chickenpox. I-VZIG ingasiza ukuvikela wena nengane yakho ezinkingeni ezinzima. Isinqumo sokusebenzisa i-VZIG ngesikhathi sokukhulelwa senziwa ngaso sonke isikhathi ngaphansi kokuqondiswa kwezokwelapha okucophelelayo.

Ngingenzani uma ngithola ngephutha i-Varicella-Zoster Immune Globulin eningi kakhulu?

Njengoba i-VZIG inikezwa ochwepheshe bezempilo ezindaweni zezokwelapha, ukweqisa ngengozi akuvamile kakhulu. Umthamo ubhalwa ngokucophelela ngokusekelwe esisindweni sakho kanye nezici eziyingozi.

Uma ukhathazekile ngomthamo owutholile, xhumana nomhlinzeki wakho wezempilo ukuze uxoxe ngezinkinga zakho. Bangabuyekeza amarekhodi akho ezokwelapha futhi bakuqinisekise ngokufaneleka komthamo wakho.

Abantu abaningi bayakwazi ukumelana ngisho nemithamo ephezulu ye-VZIG ngaphandle kwezinkinga ezinkulu, yize ungase uhlangabezane nemiphumela eminingi engemihle efana nobuhlungu endaweni yokujova noma izimpawu ezifana nomkhuhlane.

Kufanele ngenzeni uma ngiphuthelwa umthamo wami ohleliwe we-Varicella-Zoster Immune Globulin?

I-VZIG isebenza kahle kakhulu uma inikezwa kungakapheli amahora angama-96 (izinsuku ezi-4) ngemuva kokuchayeka esifo somkhuhlane wenkukhu. Uma uphuthelwa yileli windi, ukuvikeleka kungancipha, kodwa kungase kusize kuze kube yizinsuku eziyi-10 ngemuva kokuchayeka.

Xhumana nodokotela wakho ngokushesha uma uphuthelwe umthamo wakho ohleliwe. Bangahlola ukuthi kusafanele yini ukuthola i-VZIG noma ngabe ezinye izindlela zokuvimbela zingase zifaneleke kakhulu.

Ungacabangi ukuthi sekwephuze kakhulu - udokotela wakho angasiza ekunqumeni inkambo engcono kakhulu yezinto ngokusekelwe ekutheni isikhathi esingakanani selidlulile ngemuva kokuchayeka kwakho.

Ngingayeka nini ukukhathazeka nge-Chickenpox ngemuva kokuthola i-Varicella-Zoster Immune Globulin?

Ukuvikeleka okuvela ku-VZIG kuvame ukuhlala amasonto amathathu kuya kwamane. Ngesikhathi esinjalo, unokuvikeleka okukhulu ekuthuthukiseni i-chickenpox ekuchayekeni okwenza ukwelashwa.

Noma kunjalo, kufanele usabheke izimpawu kuze kube yizinsuku ezingama-28 ngemuva kokuchayeka kwakho, njengoba i-VZIG inganikezi ukuvikeleka okuyi-100%. Uma uthuthukisa noma yiziphi izimpawu ezingase zibe yi-chickenpox, xhumana nodokotela wakho ngokushesha.

Ngemuva kokuphela kwesikhathi sokuvikela samasonto amane, uzobuyela ezingeni lakho eliyisisekelo lobungozi. Uma unezici eziqhubekayo zobungozi obukhulu, xoxa ngamasu okuvimbela isikhathi eside nodokotela wakho.

Ngingayithola yini umgomo we-Chickenpox ngemuva kokuthola i-Varicella-Zoster Immune Globulin?

Ngokuvamile udinga ukulinda izinyanga eziningana ngemuva kokuthola i-VZIG ngaphambi kokuthola umgomo we-chickenpox. Ama-antibody ku-VZIG angaphazamisa ikhono lomgomo lokukhuthaza amasosha akho omzimba.

Udkt wakho ngokuvamile uzoncoma ukuthi ulinde okungenani izinyanga ezi-5 ngemuva kwe-VZIG ngaphambi kokuthola umgomo wamathumba. Lokhu kunika amasosha omzimba abolekiwe isikhathi sokuthi asuke emzimbeni wakho ukuze umgomo usebenze kahle.

Uma usengozini enkulu yezithumba, udkt wakho uzokusiza ukuthi uhlele isikhathi esingcono sokugonywa ukuze uqinisekise ukuthi uqhubeka nokuvikeleka ngenkathi uvumela umgomo ukuthi usebenze ngempumelelo.