Velaglucerase alfa (indlela ye-intravenous)

VPRIV

Ukuhlungwa kwe-Velaglucerase alfa kusetshenziswa ekwelapheni isifo seGaucher sohlobo 1. Lesi sifo sibangelwa ukungabikho kwesinye i-enzyme, i-glucocerebrosidase, emzimbeni. Le enzyme iyadingeka ukuze umzimba usebenzise amafutha ngendlela efanele, futhi amafutha azoqongelela ezindaweni ezithile zomzimba uma i-enzyme ingabikho. I-Velaglucerase alfa ithatha indawo ye-enzyme efile ukuze isize umzimba ekuqondiseni amafutha. Lolu lwemi lwezokwelapha lutholakala kuphela ngomyalo wezokwelapha. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:

Ekucatshangeni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqulu ozothatha wena nodokotela wakho. Kulo muthi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma iyiphi impendulo engaqondakali noma ebangelwa uketshezi kulo muthi noma kunoma iyiphi eminye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zoketshezi, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenalo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele ezenziwe kuze kube manje azibonakalisi izinkinga ezikhethekile zezingane ezizobeka umkhawulo ekusebenziseni ukugxilwa kwe-velaglucerase alfa kubantwana abaneminyaka engu-4 kuya kwengu-17. Kodwa-ke, ukuphepha nokuphumelela akukaqiniswa kubantwana abaneminyaka engaphansi kwengu-4. Izifundo ezifanele ezenziwe kuze kube manje azibonakalisi izinkinga ezikhethekile zabantu abadala ezizobeka umkhawulo ekusebenziseni ukugxilwa kwe-velaglucerase alfa kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izimithi kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungase kudingeke. Tshela ochwepheshe bakho bezempilo uma uthatha noma iyiphi enye imithi yokuqaphela noma engekho ngaphansi kwelayisensi (over-the-counter [OTC]). Ezinye izimithi akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba ngezinye izimithi kungase futhi kubangele ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba.