Yini i-Venlafaxine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Venlafaxine iyisidambisi sokucindezeleka esinikezwa ngudokotela esisiza ukulinganisa amakhemikhali obuchopho ukuze kuthuthukiswe imizwa futhi kuncishiswe ukukhathazeka. Ingaphansi kohlu lwemithi ebizwa ngokuthi ama-SNRI (ama-serotonin-norepinephrine reuptake inhibitors), asebenza ngokukhuphula amazinga amakhemikhali amabili obuchopho abalulekile athinta indlela ozizwa ngayo.

Le mithi ingaba yithuluzi eliwusizo ekuphatheni ukucindezeleka, ukukhathazeka, nezinye izimo ezihlobene nemizwa. Ukuqonda ukuthi isebenza kanjani nokuthi yini ongayilindela kungakusiza ukuthi uzizwe uqiniseka ngokwengeziwe ngohambo lwakho lokwelashwa.

Yini i-Venlafaxine?

I-Venlafaxine iyisidambisi sokucindezeleka esinikezwa ngudokotela esisebenza ngokulinganisa amakhemikhali ebuchosheni bakho abizwa ngokuthi ama-neurotransmitters. Ngokuqondile, ikhuphula amazinga e-serotonin kanye ne-norepinephrine, okuyizinto ezilawula imizwa yemvelo ezikusiza ukuthi uzizwe uzinzile futhi ulinganiselwe ngokomzwelo.

Le mithi ithathwa njengeqinile ngokulinganisela phakathi kwama-antidepressants. Inamandla kunezinye izidakamizwa ezindala kodwa ngokuvamile iyabekezeleleka kahle uma isetshenziswa ngendlela efanele. Udokotela wakho uyayibhala lapho ekholelwa ukuthi izinzuzo zidlula noma yiziphi izingozi ezingaba khona esimweni sakho esithile.

I-Venlafaxine iza ngezindlela ezimbili eziyinhloko: amaphilisi akhishwa ngokushesha owathatha izikhathi eziningi ngosuku, nama-capsules akhishwa isikhathi eside owathatha kanye ngosuku. Uhlobo olukhishwa isikhathi eside luvame ukukhethwa ngoba lunikeza amazinga emithi aqhubekayo usuku lonke.

Isetshenziselwani i-Venlafaxine?

I-Venlafaxine ngokuyinhloko iphatha i-major depressive disorder kanye ne-generalized anxiety disorder. Udokotela wakho angase akubhale uma uke waba nosizi oluqhubekayo, ukukhathazeka, noma ezinye izimpawu eziphazamisa impilo yakho yansuku zonke.

Ngaphandle kwalokhu kusetshenziswa okuyinhloko, le mithi ingasiza nangezinye izimo eziningi. Nazi izindlela i-venlafaxine engase isekele ngayo impilo yakho yengqondo:

• Ukuphazamiseka okukhulu kokucindezeleka (ukudabuka okuqhubekayo nokulahlekelwa intshisekelo)
• Ukuphazamiseka kokukhathazeka okujwayelekile (ukukhathazeka ngokweqile ngezimo zansuku zonke)
• Ukuphazamiseka kokukhathazeka komphakathi (ukwesaba okukhulu izimo zomphakathi)
• Ukuphazamiseka kokwethuka (ukuhlaselwa ukwethuka okungalindelekile)
• Ukuphazamiseka kokucindezeleka ngemva kwengozi (i-PTSD)
• Ukuphazamiseka okucindezelayo-okuyimpoqo (imicabango engathandeki nokuziphatha okuphindaphindwayo)

Ngezinye izikhathi odokotela banikeza i-venlafaxine ngezimo ezingavamile njengobuhlungu obungapheli noma ukushisa okukhulu ngesikhathi sokuya esikhathini. Lokhu kuthathwa njengokusebenzisa okungajwayelekile, okusho ukuthi umuthi ungasiza ngisho noma wawungenzelwe lezi zinjongo.

Isebenza Kanjani I-Venlafaxine?

I-Venlafaxine isebenza ngokuvimba ukumuncwa kabusha kwe-serotonin ne-norepinephrine ebuchosheni bakho. Cabanga ngakho njengokugcina amakhemikhali amaningi alusizo atholakala lapho amaseli obuchopho bakho angawasebenzisa ukuze axhumane kangcono.

Uma unokucindezeleka noma ukukhathazeka, lawa makhemikhali obuchopho avame ukungalingani. I-Venlafaxine isiza ukubuyisela lokho kulinganisela ngokuvimbela ubuchopho bakho ukuthi bungawasusi lawa makhemikhali ngokushesha kakhulu. Lokhu kubanika isikhathi esiningi sokwenza umsebenzi wabo wokulawula imizwa yakho nemizwa yakho.

Umuthi ngokuvamile uthatha amasonto angu-4 kuya kwangu-6 ukufinyelela umphumela wawo ogcwele, nakuba abanye abantu beqaphela ukuthuthuka ngokushesha. Lokhu kuqala kancane kwenzeka ngoba ubuchopho bakho budinga isikhathi sokuzivumelanisa nokulinganisela okusha kwamakhemikhali nokwakha amaphethini okuxhumana anempilo.

Kufanele Ngiyithathe Kanjani I-Venlafaxine?

Thatha i-venlafaxine ngendlela udokotela wakho ayalela ngayo, ngokuvamile kanye noma kabili ngosuku ngokudla. Ukuyithatha ngokudla kusiza ukunciphisa isisu esibuhlungu futhi kusiza umzimba wakho ukuba umunce umuthi ngempumelelo.

Uma usebenzisa uhlobo olukhishwe isikhathi eside, gwinya ikhaphule ngokuphelele ngamanzi. Ungalichobozi, ulihlafune, noma uvule ikhaphule, ngoba lokhu kungabangela ukuthi umuthi omningi ukhishwe ngesikhathi esisodwa. Ngamaphilisi akhishwe ngokushesha, ungaqhekeza uma udokotela wakho ekuncoma.

Zama ukuthatha umuthi wakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo ohlelweni lwakho. Abantu abaningi bakuthola kuwusizo ukuxhuma ukuthatha imithi yabo emsebenzini wansuku zonke, njengokudla kwasekuseni noma ukuxubha amazinyo abo.

Ungathatha i-venlafaxine ngaphandle kokudla, kodwa ukuyithatha nokudla kuvame ukuzwakala kukhululekile esiswini sakho. Uma uhlangabezana nesicanucanu, ukudla ukudla okulula noma ukudla ngaphambi kwesikhathi kungasiza ekunciphiseni lo mphumela ohlangothini.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Venlafaxine?

Abantu abaningi bathatha i-venlafaxine okungenani izinyanga eziyi-6 kuya kweziyi-12 ngemuva kokuthi izimpawu zabo zithuthuke. Udokotela wakho uzosebenza nawe ukunquma ubude obufanele ngokuya ngesimo sakho esithile nokuthi usabela kahle kangakanani ekwelashweni.

Ngesigameko sakho sokuqala sokucindezeleka noma ukukhathazeka, ungase uthathe umuthi izinyanga eziyi-6 kuya kweziyi-12 ngemuva kokuzizwa ungcono. Uma uke waba nezigameko eziningi, udokotela wakho angase ancome ukwelashwa isikhathi eside ukusiza ukuvimbela izimpawu ukuthi zingabuyi.

Abanye abantu bayazuza ekuthathweni kwe-venlafaxine iminyaka eminingi, ikakhulukazi uma benemibandela engapheli noma beke bahlangabezana nezigameko eziningi zokucindezeleka noma ukukhathazeka. Lokhu akuyona into engavamile futhi kungaba yingxenye ebalulekile yokugcina ukuzinza kwempilo yakho yengqondo.

Ungayeki ukuthatha i-venlafaxine ngokuzumayo, ngisho noma uzizwa ungcono. Udokotela wakho uzokusiza ukuthi unciphise kancane kancane umthamo emasontweni ambalwa ukugwema izimpawu zokuhoxiswa. Le nqubo yokunciphisa ivumela ubuchopho bakho ukuthi buvumelane kancane kancane nokusebenza ngaphandle komuthi.

Yiziphi Imiphumela Eceleni Ye-Venlafaxine?

Njengayo yonke imithi, i-venlafaxine ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala.

Nawa amanye emiphumela emibi evame kakhulu ongase uyithole, ikakhulukazi emasontweni ambalwa okuqala okwelashwa:

• Ukucanuzela kwenhliziyo noma isisu esibuhlungu
• Ikhanda elibuhlungu
• Isiyezi noma ukukhathala
• Umlomo owomile
• Ukuqunjelwa
• Ukozela noma ukukhathala
• Ukujuluka okuningi kunokujwayelekile
• Ushintsho ekudleni
• Izinkinga zokulala (ukuqwasha noma amaphupho acacile)

Le miphumela emibi ejwayelekile ivame ukushabalala njengoba umzimba wakho ujwayela umuthi. Ukuthatha i-venlafaxine nokudla kungasiza ukunciphisa ukucanuzela kwenhliziyo, futhi ukuhlala unamanzi kungasiza ngomlomo owomile nokuqunjelwa.

Abanye abantu bathola imiphumela emibi engavamile kodwa ebonakala kakhulu edinga ukunakekelwa okwengeziwe:

• Imiphumela emibi yocansi (ukwehla kwentshisekelo noma ubunzima bokufinyelela umvuthwandaba)
• Ushintsho lwesisindo (ukuzuza noma ukulahlekelwa)
• Ukubona okungacacile
• Ukuthuthumela noma ukuzamazama
• Ukukhuphuka kwegazi
• Ukukhala ezindlebeni (i-tinnitus)
• Ukuqina noma ukopha okungavamile

Nakuba kungavamile, eminye imiphumela emibi engathi sína idinga ukunakekelwa kwezokwelapha ngokushesha. Xhumana nodokotela wakho ngokushesha uma uthola noma yikuphi kwalokhu:

• Imicabango yokuzibulala noma ukuzilimaza
• Ushintsho olukhulu lwemizwa noma ukucasuka
• Ubuhlungu besifuba noma ukushaya kwenhliziyo okungajwayelekile
• Ikhanda elibuhlungu elinamandla nokuqina kwentamo
• Ukuhlaselwa
• Izimpawu ze-serotonin syndrome (umkhuhlane, ukuqina kwemisipha, ukudideka)
• Ukungezwani komzimba okukhulu (ukuqubuka, ukuvuvukala, ubunzima bokuphefumula)

Khumbula ukuthi udokotela wakho unqume lo muthi ngoba bakholelwa ukuthi izinzuzo zidlula izingozi kuwe. Abantu abaningi bayayibekezelela i-venlafaxine kahle, futhi imiphumela emibi engathi sína ayivamile uma umuthi usetshenziswa ngendlela efanele.

Ubani Ongafanele Athatha I-Venlafaxine?

Abantu abathile kufanele bagweme i-venlafaxine noma bayisebenzise ngokuqapha okwengeziwe. Udokotela wakho uzobukeza umlando wakho wezokwelapha kanye nemithi yamanje ukuze anqume ukuthi lo muthi uphephile yini kuwe.

Akufanele uthathe i-venlafaxine uma njengamanje uthatha noma usanda kuyeka ukuthatha ama-MAOI (ama-monoamine oxidase inhibitors). Le mithi ingasebenzisana ngendlela eyingozi ne-venlafaxine, ngakho-ke ngokuvamile udinga ukulinda okungenani izinsuku eziyi-14 phakathi kokuyeka enye nokuqala enye.

Izimo eziningana zezokwelapha zidinga ukucatshangelwa okukhethekile ngaphambi kokuqala i-venlafaxine:

• Umfutho wegazi ophezulu ongagadiwe
• Ukuhlaselwa yisifo senhliziyo kwakamuva noma izinkinga zesigqi senhliziyo
• Isifo esibi sezinso noma sesibindi
• Umlando wokuhlaselwa yisithuthwane noma isithuthwane
• Izifo zokuphuma igazi noma ukuthatha izinciphisi zegazi
• I-glaucoma ye-narrow-angle
• Umlando wama-episode e-manic (isifo se-bipolar)

Abantu abadala abangaphansi kweminyaka engu-25 badinga ukuqashwa eduze lapho beqala i-venlafaxine, njengoba ama-antidepressants ngezinye izikhathi ekuqaleni engase andise imicabango yokuzibulala kulolu hlu lweminyaka. Lokhu akusho ukuthi umuthi awuphephile, kodwa udokotela wakho uzofuna ukukubona njalo ezinyangeni ezimbalwa zokuqala.

Uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa, xoxa ngezingozi nezinzuzo nodokotela wakho. Ngenkathi i-venlafaxine ingasetshenziswa ngesikhathi sokukhulelwa uma kunesidingo, idinga ukucatshangelwa ngokucophelela kwemiphumela engaba khona kuwe nakumntwana wakho.

Amagama Omkhiqizo we-Venlafaxine

I-Venlafaxine itholakala ngaphansi kwamagama amaningana omkhiqizo, i-Effexor ne-Effexor XR iyona eyaziwa kakhulu. Elithi "XR" limele ukukhishwa okweluliwe, okusho ukuthi umuthi ukhishwa kancane usuku lonke.

Amanye amagama omkhiqizo afaka i-Pristiq (okuyimithi ehlobene ebizwa ngokuthi i-desvenlafaxine), kanye nezinhlobo ezahlukahlukene ze-generic. I-Venlafaxine ye-Generic iqukethe isithako esifanayo esisebenzayo futhi isebenza ngempumelelo njengezinhlobo zegama lomkhiqizo.

Ikhemisi lakho lingase lithathele indawo ye-venlafaxine ejwayelekile ngezinhlobo ezinophawu lwegama ngaphandle uma udokotela wakho ecela ngqo igama lomkhiqizo. Lokhu kujwayelekile ngokuphelele futhi kungasiza ekunciphiseni izindleko zakho zemithi ngenkathi kunikezwa izinzuzo ezifanayo zokwelapha.

Ezinye izindlela ze-Venlafaxine

Uma i-venlafaxine ingakulungele, imithi eminingi ehlukile ingelapha ukucindezeleka nokukhathazeka. Udokotela wakho angase acabangele ezinye izinhlobo ze-SNRIs, SSRIs, noma amanye amakilasi e-antidepressants ngokuya ngezimpawu zakho ezithile nomlando wezokwelapha.

Eminye imithi ye-SNRI ihlanganisa i-duloxetine (Cymbalta) ne-desvenlafaxine (Pristiq). Lezi zisebenza ngendlela efanayo ne-venlafaxine kodwa zingase zibe nemiphumela emibi ehlukile kancane noma amashejuli okulinganisa asebenza kangcono kwabanye abantu.

Imithi ye-SSRI efana ne-sertraline (Zoloft), i-fluoxetine (Prozac), ne-escitalopram (Lexapro) nayo iyizindlela ezivamile. Le mithi igxila ikakhulukazi ku-serotonin kunokuba kokubili i-serotonin ne-norepinephrine.

Kwabanye abantu, amakilasi amadala e-antidepressants afana nama-tricyclics noma izinketho ezintsha ezifana ne-bupropion (Wellbutrin) zingase zifaneleke kakhulu. Udokotela wakho uzocabangela izimpawu zakho, umlando wezokwelapha, nendlela yokuphila ukuze athole inketho engcono kakhulu kuwe.

Ingabe i-Venlafaxine ingcono kune-Sertraline?

Kokubili i-venlafaxine ne-sertraline ziyizidambisi zokucindezeleka ezisebenzayo, kodwa zisebenza ngendlela ehlukile kancane futhi zingase zifaneleke kangcono kubantu abahlukene. Akukho noyedwa ongcono ngokujwayelekile - ukukhetha okungcono kuncike ezimpawini zakho ngazinye nokuthi umzimba wakho usabela kanjani.

I-Venlafaxine ithinta kokubili i-serotonin ne-norepinephrine, kuyilapho i-sertraline ithinta ikakhulukazi i-serotonin. Lokhu kusho ukuthi i-venlafaxine ingase isebenze kahle kubantu abanezinhlobo ezithile zokucindezeleka noma ukukhathazeka, ikakhulukazi labo abanamandla aphansi noma isisusa.

I-Sertraline ivame ukuba nemiphumela emincane emayelana nomfutho wegazi nokuhoxiswa, okwenza kube lula ukuyeka uma kudingeka. Kodwa-ke, i-venlafaxine ingase isebenze kangcono ekucindezelekeni okukhulu noma ukukhathazeka okungaphendulanga kahle kwezinye izindlela zokwelapha.

Udokotela wakho uzocabangela izinto ezinjengezimpawu zakho ezithile, umlando wakho wezokwelapha, eminye imithi oyithathayo, nendlela yakho yokuphila ukuze anqume ukuthi iyiphi inketho engasebenza kangcono kuwe. Kwesinye isikhathi kuthatha ukuzama imithi ehlukene ukuze uthole leyo enikeza ibhalansi engcono kakhulu yokusebenza kahle nokubekezeleleka.

Imibuzo Evame Ukubuzwa Nge-Venlafaxine

Ingabe i-Venlafaxine iphephile ezinkingeni zenhliziyo?

I-Venlafaxine ingathinta umfutho wegazi nesilinganiso senhliziyo, ngakho-ke abantu abanezimo zenhliziyo badinga ukuqapha ngokucophelela. Udokotela wakho uzohlola umfutho wakho wegazi njalo futhi angase alungise umthamo wakho noma akhethe omunye umuthi uma unezinkinga ezinkulu zenhliziyo.

Uma unezimo zenhliziyo ezilula, i-venlafaxine ingase isaphephe ngokuqapha okufanele. Kodwa-ke, uma uke wahlaselwa yinhliziyo yamuva noma unomfutho wegazi ophezulu ongagadiwe, udokotela wakho cishe uzoncoma ezinye izindlela zokwelapha.

Ngingenzani uma ngiphuzile i-Venlafaxine eningi ngengozi?

Uma ngengozi uthatha i-venlafaxine eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela izimpawu ezinzima njengokushaya kwenhliziyo okusheshayo, umfutho wegazi ophezulu, ukuquleka, noma ukulahlekelwa ukwazi.

Ungalindi ukubona ukuthi ngabe izimpawu ziyavela yini - funa usizo lwezokwelapha ngokushesha. Letha ibhodlela lomuthi nawe ukuze abahlinzeki bezempilo bazi kahle ukuthi yini nokuthi ungakanani okuthathile.

Ngingenzani uma ngiphuthelwe umthamo we-Venlafaxine?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe.

Ezinhlotsheni ezikhishwe isikhathi eside, ukweqa umthamo ngezikhathi ezithile ngeke kubangele izinkinga ezinkulu, kodwa zama ukugcina isimiso sakho esivamile ngangokunokwenzeka. Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi.

Ngingayeka nini ukuthatha i-Venlafaxine?

Ungayeki ukuthatha i-venlafaxine ngokuzumayo, ngisho noma uzizwa ungcono ngokuphelele. Udokotela wakho uzokusiza ukuthi unciphise kancane umthamo emasontweni amaningana noma izinyanga ukuvimbela izimpawu zokuhoxisa njengokugajwa, izimpawu ezinjenge-flu, noma "ama-brain zaps."

Odokotela abaningi batusa ukuqhubeka nokwelashwa okungenani izinyanga eziyi-6 kuya kweziyi-12 ngemuva kokuthi izimpawu zakho zithuthuke. Lokhu kusiza ekuvikeleni izimpawu ukuthi zingabuyi futhi kunikeza ubuchopho bakho isikhathi sokusungula amaphethini anempilo.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Venlafaxine?

Kungcono ukugwema utshwala noma uphuze amanani amancane kuphela ngenkathi uthatha i-venlafaxine. Utshwala bungandisa ukozela nokugajwa, futhi bungaphazamisa nokusebenza kahle komuthi ekwelapheni ukucindezeleka kwakho noma ukukhathazeka.

Uma ukhetha ukuphuza ngezikhathi ezithile, yenza kanjalo ngokucophelela futhi unake indlela ozizwa ngayo. Abanye abantu bathola ukuthi utshwala bubathinta ngokuqinile ngenkathi bethatha i-venlafaxine, ngakho qala ngokuphuza okuncane kunalokho obungajwayele ukuphuza.