Yini i-Verteporfin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Verteporfin yimithi esebenza ngokukhanya esetshenziselwa ukwelapha izimo ezithile zamehlo ezingathi sína ezingaholela ekulahlekelweni umbono. Isebenza ngenqubo ekhethekile ebizwa ngokuthi i-photodynamic therapy, lapho imithi ifakwa emithanjeni yakho bese isebenziswa ngohlobo oluthile lokukhanya kwe-laser okusetshenziswa emehlweni akho.

Lokhu kwelashwa kusetshenziswa ikakhulukazi ekugugeni kwe-macular okuhlobene nobudala nezinye izimo lapho imithambo yegazi engavamile ikhula ngemuva kwamehlo akho. Ngenkathi igama lingase lizwakale liyinkimbinkimbi, i-verteporfin isize abantu abaningi ukuthi balondoloze umbono wabo lapho ezinye izindlela zokwelapha zazingezona izinketho ezifanele.

Yini i-Verteporfin Esetshenziselwa Yona?

I-Verteporfin iphatha izimo ezithile zamehlo lapho imithambo yegazi engavamile ibangela izinkinga zombono. Ukusetshenziswa okuvame kakhulu kuhlobo lokuguga kwe-macular okuhlobene nobudala okubizwa ngokuthi i-“wet” AMD, lapho imithambo yegazi evuzayo ilimaza ingxenye emaphakathi yombono wakho.

Udokotela wakho wamehlo angase ancome i-verteporfin uma unalokho okubizwa ngokuthi i-“predominantly classic” choroidal neovascularization. Lokhu kusho ukuthi imithambo yegazi engavamile ikhule ngaphansi kwe-retina yakho futhi ibangela ukuvuza koketshezi noma ukopha okusongela umbono wakho ophakathi.

Imithi ngezinye izikhathi isetshenziselwa ezinye izimo ezinjengezinkinga ze-pathologic myopia noma izinhlobo ezithile ze-choroidal hemangiomas. Lezi yizimo ezingavamile lapho ukukhula okufanayo kwemithambo yegazi engavamile kwenzeka emehlweni.

Isebenza Kanjani i-Verteporfin?

I-Verteporfin ithathwa njengemithi enamandla aphakathi nendawo esebenza ngenqubo ekhethekile yezinyathelo ezimbili. Okokuqala, imithi ifakwa emthanjeni engalweni yakho, lapho ihamba ngemithambo yakho yegazi ukuze ifinyelele emithanjeni yegazi engavamile emehlweni akho.

Ngemuva kwemizuzu engaba ngu-15 ngemuva komjovo, udokotela wakho usebenzisa ukukhanya okukhethekile kwe-laser okubomvu esweni lakho imizuzwana engama-83 ngqo. Lokhu kukhanya kwenza i-verteporfin, okuyenza ikhiqize izinto ezisiza ukuvala imithambo yegazi enezinkinga ngaphandle kokulimaza izicubu ezinempilo ezizungezile.

Cabanga ngakho njengokwelashwa okuhloswe ngakho okusebenza kuphela lapho ukukhanya kwe-laser kusetshenziswa khona. Umuthi ngokwawo awulimazi kuze kube yilapho uvulwa yi-wavelength ethile yokukhanya, okwenza kube ngqo ekwelapheni indawo ethintekile kuphela.

Ngingayithatha kanjani i-Verteporfin?

I-Verteporfin ihlala inikezwa njengomjovo we-intravenous endaweni yezokwelapha, hhayi njengepilisi noma amaconsi esweni. Uzothola ukwelashwa ehhovisi likadokotela wakho noma emtholampilo ongagcini esibhedlela lapho benemishini ekhethekile ye-laser edingekayo.

Umjovo ngokwawo uthatha imizuzu engaba ngu-10, ngesikhathi umuthi unikezwa kancane ngomthambo engalweni yakho. Akudingeki ukuthi wenze lutho olukhethekile ukulungiselela, yize udokotela wakho angakucela ukuthi ugweme ukudla ukudla okukhulu ngaphambi kwesikhathi ukuvimbela noma yikuphi ukucasuka.

Ngemuva komjovo, uzolinda imizuzu engaba ngu-15 ngaphambi kokuthi ukwelashwa nge-laser kuqale. Ngesikhathi salokhu kulinda, umuthi ujikeleza emzimbeni wakho futhi uqongelela emithanjeni yegazi engavamile esweni lakho.

Ngingayithatha isikhathi esingakanani i-Verteporfin?

Ubude bokwelashwa nge-verteporfin buhlukahluka kakhulu kuye ngokuthi iso lakho lisabela kanjani ekwelashweni. Abantu abaningi badinga ukwelashwa okuningi okuhlukaniswe cishe izinyanga ezintathu ukuze bathole imiphumela engcono kakhulu.

Udokotela wakho wamehlo uzoqapha inqubekela phambili yakho ngezivivinyo zamehlo ezivamile kanye nezivivinyo ezikhethekile zokucabanga. Uma imithambo yegazi engavamile iqala ukukhula futhi noma uma uketshezi lubuya, ungase udinge ukwelashwa okwengeziwe. Abanye abantu badinga iseshini eyodwa noma ezimbili kuphela, kanti abanye bangase badinge ukwelashwa okuningi ngonyaka noma ngaphezulu.

Isinqumo sokuqhubeka noma ukuyeka ukwelashwa sincike ngokuphelele ekutheni iso lakho lisabela kahle kangakanani nokuthi izinzuzo zidlula yini noma yiziphi izingozi. Udokotela wakho uzoxoxa lokhu nawe ekuqokweni ngakunye okulandelayo.

Yiziphi Imiphumela Eceleni Ye-Verteporfin?

Abantu abaningi bayakwazi ukumelana ne-verteporfin kahle, kodwa njenganoma imuphi umuthi, ingabangela imiphumela emibi. Into ebaluleke kakhulu okufanele uyazi ukuthi uzoba nobucayi obukhulu ekukhanyeni izinsuku eziningana ngemuva kokwelashwa.

Nawa amanye imiphumela emibi evame kakhulu ongase uyithole, futhi ukuyiqonda kungakusiza ukuthi ulungiselele futhi wazi ukuthi yini ongayilindela:

• Ukuzwela okukhulu ekukhanyeni: Lokhu kuthinta cishe wonke umuntu futhi kungahlala izinsuku eziyi-1-2. Uzodinga ukugwema izibani ezikhanyayo, ukukhanya kwelanga, ngisho nokukhanya kwangaphakathi endlini
• Ushintsho embonweni: Ukubona okungacacile okwesikhashana, ukubona amabala amnyama, noma izinguquko ekuboneni umbala izinsuku ezimbalwa
• Ukuphendula kwendawo yokujova: Ubuhlungu, ukuvuvukala, noma ukushintsha kombala lapho i-IV ibekwe khona
• Ubuhlungu emhlane: Abanye abantu bazwa ukungakhululeki okuncane kuya kokulingene emhlane ngesikhathi noma ngemuva kokufakwa
• Isicanucanu: Ngokuvamile kulula futhi okwesikhashana, kwenzeka ngesikhathi noma ngemuva nje kokwelashwa

Le miphumela ejwayelekile ngokuvamile iyalawuleka futhi iyanyamalala ezinsukwini ezimbalwa. Ithimba lakho lezokwelapha lizokunikeza imiyalelo ethile yokuzivikela ekukhanyeni.

Imiphumela emibi engavamile kodwa ebucayi ingenzeka, nakuba ingavamile. Lokhu kungabandakanya ukusabela okukhulu komzimba, ukulahlekelwa okukhulu kombono, noma izinkinga ezivela ekuzweleni ukukhanya uma izinyathelo ezifanele zingalandelwa.

Abanye abantu bazwa ubuhlungu besifuba, ubunzima bokuphefumula, noma ubuhlungu obukhulu emhlane ngesikhathi sokufakwa. Uma noma yikuphi kwalokhu kwenzeka, ithimba lakho lezokwelapha lizoyeka ukwelashwa ngokushesha futhi linikeze ukunakekelwa okufanele.

Ubani Ongafanele Athole I-Verteporfin?

I-Verteporfin ayifanele wonke umuntu, futhi udokotela wakho uzohlola ngokucophelela ukuthi ikufanele yini. Abantu abanezimo ezithile noma ezimweni ezithile kufanele bagweme lokhu kwelashwa.

Akufanele uthole i-verteporfin uma unokungezwani komzimba emuthini uqobo noma kunoma yiziphi izithako zawo. Ngaphezu kwalokho, uma une-porphyria, isifo esingavamile segazi esithinta indlela umzimba wakho oqhubula ngayo amakhemikhali athile, lokhu kwelashwa kungaba yingozi.

Abesifazane abakhulelwe akufanele bathole i-verteporfin, njengoba imiphumela yayo ezinganeni ezisakhula ingaziwa ngokugcwele. Uma uncelisa, udokotela wakho uzoxoxa ngokuthi ngabe izinzuzo zidlula yini izingozi ezingaba khona, njengoba amanani amancane omuthi angase adlulele obisini lwebele.

Abantu abanezinkinga ezinkulu zesibindi kungenzeka bangabi ngabazali abahle, njengoba umuthi uqhutshwa ngesibindi. Udokotela wakho uzobuyekeza umlando wakho wezokwelapha futhi angase ayale ukuhlolwa kwegazi ukuze ahlolisise ukusebenza kwesibindi sakho ngaphambi kokwelashwa.

Igama Lomkhiqizo we-Verteporfin

I-Verteporfin ithengiswa ngaphansi kwegama lomkhiqizo elithi Visudyne. Lolu uhlobo olutholakala kakhulu lomuthi futhi yilolo udokotela wakho angase alubhale.

I-Visudyne iza njengempushana exutshwe namanzi ahlanzekile ukudala isixazululo sokujova. Ukuxuba kwenziwa njalo ochwepheshe bezokwelapha abaqeqeshiwe ngaphambi nje kokwelashwa kwakho ukuqinisekisa ukuthi umuthi umusha futhi ulungiswe kahle.

Ezinye izindlela zokwelapha ze-Verteporfin

Ezinye izindlela eziningana zokwelapha ziyatholakala ezimweni zamehlo i-verteporfin elapha zona, futhi udokotela wakho uzokusiza ukuthi uqonde ukuthi iyiphi inketho engasebenza kahle esimweni sakho esithile.

Ukujova kwe-Anti-VEGF, njenge-ranibizumab (Lucentis) noma i-aflibercept (Eylea), ngokuvamile kuyindlela yokuqala yokwelapha i-macular degeneration emanzi. Le mithi ijojwa ngqo esweni futhi isebenza ngokuvimba ukukhula kwemithambo yegazi engavamile.

Kwabanye abantu, i-thermal laser photocoagulation ingase ibe yindlela yokwelapha, nakuba lokhu kungasetshenziswa kakhulu namuhla. Lokhu kwelapha kusebenzisa ukushisa ukuvala imithambo yegazi evuzayo, kodwa kungabangela umonakalo omkhulu ezicutshini ezizungezile kune-verteporfin.

Ezimweni ezithile, udokotela wakho angase ancome ukuhlanganiswa kokwelashwa noma asikisela ukuqapha ngaphandle kokungenelela ngokushesha, ikakhulukazi uma isimo siqhubeka kancane futhi singayithinti ngokuphawulekayo imibono yakho.

Ingabe i-Verteporfin Ingcono Kune-Anti-VEGF Injections?

Noma ngabe i-verteporfin ingcono kune-anti-VEGF injections kuncike esimweni sakho samehlo esithile kanye nezimo zomuntu ngamunye. Zombili izindlela zokwelapha zinezinzuzo zazo futhi zifanele izimo ezihlukene.

I-Anti-VEGF injections ngokuvamile zithathwa njengendlela yokwelapha yokuqala ye-wet macular degeneration ngoba zingathuthukisa ngempela umbono ezimweni eziningi. Ziphinde zinikezwe kaningi kodwa zinikezwa ngqo esweni kunokuba zithathwe nge-IV.

I-Verteporfin ingase ithandwe uma unohlobo oluthile lokukhula kwemithambo yegazi olusabela kangcono ekwelashweni kwe-photodynamic, noma uma ungazange usabele kahle ekwelashweni kwe-anti-VEGF. Futhi iyindlela uma ungenakukwazi ukubekezelela ukujovwa kwamehlo njalo.

Udokotela wakho wamehlo uzocabangela izinto ezinjengosayizi nendawo yemithambo yegazi engavamile, impilo yakho yonke, nezintandokazi zakho lapho encoma indlela yokwelapha engcono kakhali kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Verteporfin

Ingabe i-Verteporfin Iphephile Kubantu Abanezifo Zenhliziyo?

I-Verteporfin ngokuvamile ingasetshenziswa ngokuphepha kubantu abanezifo zenhliziyo, kodwa udokotela wakho uzodinga ukuhlola isimo sakho esithile ngokucophelela. Umuthi awuthinti ngokuqondile inhliziyo, kodwa ukucindezeleka kwanoma iyiphi inqubo yezokwelapha ngezinye izikhathi kungathinta abantu abanezifo zenhliziyo.

Uma unomlando wezinkinga zenhliziyo, qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi yakho yenhliziyo nanoma yiziphi izinguquko zakamuva empilweni yakho yenhliziyo. Bangase bafune ukuxhumana nodokotela wakho wenhliziyo noma bakuqaphele eduze ngesikhathi sokwelashwa.

Kufanele Ngenzeni Uma Ngiziveza Ngengozi Ekukhanyeni Okukhanyayo Ngemva Kokwelashwa?

Uma ngengozi uziveza ekukhanyeni okukhanyayo ngemva kokwelashwa nge-verteporfin, ngena ekamelweni elimnyama ngokushesha futhi uthinte ihhovisi likadokotela wakho. Ungabi nokwethuka, kodwa kumele ukuthathe lokhu ngokungathí sina njengoba kungabangela ukusha kwesikhumba noma kwenze ukuzwela kwakho ekukhanyeni kube kubi kakhulu.

Sebenzisa izindwangu ezipholile, ezimanzi esikhumbeni esiveziwe esizwa sifudumele noma sibukeka sibomvu. Gwema ukuvezwa okwengeziwe ekukhanyeni futhi ulandele imiyalelo kadokotela wakho yokuzivikela. Ukuvezwa okuningi okwenzeka ngengozi kuholela ekungakhululeki kwesikhashana kunokulimala okukhulu, kodwa ukuhlolwa kwezokwelapha kubalulekile.

Kufanele Ngenzeni Uma Ngiphuthelwa Ukwelashwa Nge-Verteporfin Okuhleliwe?

Uma uphuthelwa ukwelashwa nge-verteporfin okuhleliwe, thinta ihhovisi likadokotela wakho ngokushesha ngangokunokwenzeka ukuze uhlele kabusha. Isikhathi sokwelashwa sibalulekile ekugcineni izinzuzo nasekuvikeleni ukuqhubeka kwesimo samehlo akho.

Ungazami ukwenza ngaphezu kokwelashwa okuphuthelwe ngokuhlela izikhathi ezengeziwe. Udokotela wakho uzoqoka isikhathi esingcono kakhulu sokwelashwa kwakho okulandelayo ngokusekelwe ekutheni sekudlule isikhathi esingakanani kusukela kokugcina kwakho nokuthi isimo samehlo akho siqhubeka kanjani.

Ngingayeka nini ukuthatha i-Verteporfin?

Ungayeka ukwelashwa nge-verteporfin lapho udokotela wakho enquma ukuthi akusazuzi noma akudingekile. Lesi sinqumo sisekelwe ekuqapheliseni njalo isimo samehlo akho nokuthi usabela kahle kangakanani ekwelashweni.

Abanye abantu badinga ukwelashwa okukodwa noma okubili kuphela bese begcina umbono ozinzile iminyaka eminingi. Abanye bangase badinge ukwelashwa okuqhubekayo ngezikhathi ezithile. Ungalokothi uyeke ukwelashwa wedwa, njengoba isimo samehlo esingaphansi singase sibe sibi ngaphandle kokuphathwa okufanele.

Ngingashayela Ngemva Kokwelashwa Nge-Verteporfin?

Akufanele ushayele ngemva nje kokwelashwa nge-verteporfin ngenxa yezinguquko embonweni nokuzwela ekukhanyeni. Hlela ukuthi othile akuqhubele ekhaya emva kokuhlolwa kwakho futhi gwema ukushayela kuze kube yilapho umbono wakho ubuyela kokujwayelekile futhi ukwazi ukubekezelela ukukhanya okujwayelekile.

Abantu abaningi bangakwazi ukuqala kabusha ukushayela ezinsukwini ezimbalwa, kodwa lokhu kuyahlukahluka kumuntu nomuntu. Xhumana nodokotela wakho mayelana nokuthi kuphephile nini ukuthi uphinde ushayele, futhi qiniseka ukuthi uzizwa ukhululekile ngombono wakho ngaphambi kokungena ngemuva kwesondo.