Yini i-Vilazodone: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Vilazodone iyikhambi elibhalwe ngudokotela elilwa nokucindezeleka elisiza ukwelapha ukucindezeleka okukhulu kubantu abadala. Ingaphansi kohlobo olusha lwama-antidepressants olubizwa ngokuthi ama-serotonin partial agonist reuptake inhibitors (SPARIs), asebenza ngendlela ehlukile kunezindlela zokwelapha ukucindezeleka ezindala. Ungase uyazi kangcono ngegama layo lomkhiqizo elithi Viibryd, futhi yakhelwe ukusiza ukubuyisela ibhalansi ye-serotonin ebuchosheni bakho ngenkathi kungenzeka ukuthi ibangela imiphumela emincane yezocansi kunamanye ama-antidepressants.

Yini i-Vilazodone?

I-Vilazodone uhlobo oluyingqayizivele lwe-antidepressant oluhlanganisa izindlela ezimbili ezihlukene zokusiza ukwelapha ukucindezeleka. Ngokungafani nama-antidepressants endabuko asebenza ngendlela eyodwa nje, i-vilazodone ivimba ukuthathwa kabusha kwe-serotonin futhi ivule izingxenye zama-serotonin receptors ebuchosheni bakho. Lesi senzo esiphindwe kabili sisiza ukwandisa ukutholakala kwe-serotonin, isithunywa samakhemikhali esidlala indima ebalulekile ekulawuleni imizwa.

Umuthi wakhiwe ngokuqondile ukubhekana nemikhawulo ethile yama-antidepressants amadala, ikakhulukazi mayelana nemiphumela yezocansi. Ithathwa njenge-antidepressant enamandla aphakathi nendawo engasebenza kubantu abaningi abanokucindezeleka ngenkathi kungenzeka ukuthi ithambile emsebenzini wezocansi uma iqhathaniswa nama-SSRIs afana ne-sertraline noma i-paroxetine.

Yini i-Vilazodone Esetshenziselwa Yona?

I-Vilazodone ngokuyinhloko ibhalwe ukwelapha ukucindezeleka okukhulu kubantu abadala abaneminyaka engu-18 nangaphezulu. Udokotela wakho angase akutuse uma uhlangabezana nemizwa eqhubekayo yokudabuka, ukungabi nathemba, noma ukulahlekelwa intshisekelo emisebenzini obuyijabulela ngaphambili. Ilusizo ikakhulukazi kubantu abaye bazama ezinye izindlela zokwelapha ukucindezeleka kodwa bahlangabezana nemiphumela yezocansi ekhathazayo.

Noma ukucindezeleka kuyindlela yayo esemqoka evunyelwe, odokotela abathile bangase babhale i-vilazodone ngaphandle kwesitifiketi sokukhathazeka, nakuba lokhu kungewona umkhomba wayo oyinhloko. Umuthi usebenza kahle kubantu abanokucindezeleka okuphakathi nendawo kuya kokukhulu okudinga ukwelashwa kwansuku zonke okuqhubekayo ukuze baphathe izimpawu zabo ngempumelelo.

Isebenza Kanjani I-Vilazodone?

I-Vilazodone isebenza ngendlela ephindwe kabili eyenza ukuthi ihluke kwamanye ama-antidepressants. Okokuqala, ivimba ukuthathwa kabusha kwe-serotonin, okusho ukuthi ivimbela ubuchopho bakho ukuthi bususe ngokushesha le khemikhali elawula imizwa ezindaweni eziphakathi kwamangqamuzana ezinzwa. Okwesibili, yenza kusebenze ngokwengxenye izamukeli ezithile ze-serotonin, okusiza ukulungisa indlela ubuchopho bakho obusabela ngayo ku-serotonin.

Cabanga ngayo njengokwandisa inani le-serotonin elitholakalayo nokusiza ubuchopho bakho ukuthi buyisebenzise ngempumelelo. Le ndlela yokuhlanganisa ngokuvamile ithatha amasonto angu-4 kuya kwangu-6 ukukhombisa imiphumela yayo ephelele, nakuba abanye abantu bengase babone ukuthuthuka ekulaleni noma ekudleni phakathi nesonto lokuqala noma amabili. Umuthi uthathwa njengonamandla ngokulinganisela, okusho ukuthi usebenza kahle kubantu abaningi abanokucindezeleka kodwa kungenzeka ukuthi akuyona inketho engcono kakhulu ezimweni ezinzima kakhulu.

Ngingayithatha Kanjani I-Vilazodone?

I-Vilazodone kumele ithathwe nokudla ukuze kuqinisekiswe ukumuncwa okufanele futhi kunciphise ukuphazamiseka kwesisu. Yithathe ngesikhathi esifanayo nsuku zonke, okungcono kakhulu ngokudla okukhulu okuqukethe okungenani ama-calories angu-300-400. Lokhu akuyona nje isiphakamiso - ukuyithatha ngaphandle kokudla kunganciphisa inani lomuthi umzimba wakho owumuncayo ngama-50%.

Abantu abaningi baqala nge-10mg kanye ngosuku ngesonto lokuqala, bese benyusa ku-20mg nsuku zonke ngesonto lesibili, futhi ekugcineni bafinyelele umthamo oqondiwe ongu-40mg nsuku zonke. Udokotela wakho uzokuqondisa ngale nyathelo ngenyathelo ukuze asize umzimba wakho ukuthi ulungise futhi unciphise imiphumela emibi. Gwinya amaphilisi wonke ngamanzi, futhi ungawachobozi, uwahlafune, noma uwaqhekeze.

Uma unzima ukukhumbula ukuyithatha ngokudla, zama ukusetha i-alamu yansuku zonke yesikhathi sokudla. Abantu abaningi bakuthola kuwusizo ukuthatha i-vilazodone nge-breakfast noma isidlo sakusihlwa, noma yisiphi isidlo esiqhubeka njalo emsebenzini wabo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Vilazodone?

Abantu abaningi badinga ukuthatha i-vilazodone okungenani izinyanga eziyi-6 kuya kweziyi-12 uma izimpawu zabo zokucindezeleka zithuthuka. Lesi sigaba sokuqhubeka sisiza ukuvimbela ukucindezeleka ukuthi kungabuyi, okuvame ukwenzeka uma ama-antidepressants eyekwa ngaphambi kwesikhathi. Udokotela wakho uzosebenza nawe ukunquma ubude obufanele ngokuya ngesimo sakho somuntu ngamunye nomlando.

Kubantu abahlangabezana nesiqephu sabo sokuqala sokucindezeleka, ukwelashwa kuvame ukuthatha izinyanga eziyi-6 kuya kweziyi-12 ngemuva kokuthi izimpawu zithuthuke. Uma uke waba neziqephu eziningi zokucindezeleka, udokotela wakho angase ancome ukwelashwa kwesikhathi eside ukusiza ukuvimbela iziqephu zesikhathi esizayo. Abanye abantu bayazuza ekuthathweni kwe-vilazodone iminyaka eminingana, ikakhulukazi uma beke baba nokucindezeleka okuphindaphindayo.

Ungayeki ukuthatha i-vilazodone ngokuzumayo, ngisho noma uzizwa ungcono. Udokotela wakho uzokusiza ukuthi unciphise kancane umthamo emasontweni ambalwa ukuze ugweme izimpawu zokuhoxiswa njengokugajezela, isicanucanu, noma izinguquko zemizwa.

Yiziphi Izimo Ezingezinhle Ze-Vilazodone?

Njengayo yonke imithi, i-vilazodone ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle. Imiphumela emibi evame kakhulu ngokuvamile ithambile futhi ivame ukuthuthuka njengoba umzimba wakho uzivumela emuthini emasontweni ambalwa okuqala.

Nawa amanye amiphumela emibi ebikwa kaningi ethinta ngaphezu kuka-5% wabantu abathatha i-vilazodone:

• Isicanucanu nokucasuka kwesisu (ikakhulukazi emasontweni ambalwa okuqala)
• Ukuqunjelwa noma izitulo ezixekile
• Ukugajezela noma ukuzizwa unovalo
• Ubunzima bokulala noma amaphupho angajwayelekile
• Ukukhathala noma ukuzizwa ukhathele emini
• Umlomo owomile
• Ukuncipha kwesifiso sokudla

Iningi lale miphumela emibi lingeyesikhashana futhi livame ukushabalala njengoba umzimba wakho ujwayela umuthi. Ukuthatha i-vilazodone nokudla kunganciphisa kakhulu isicanucanu nemiphumela emibi ehlobene nesisu.

Abanye abantu bahlangabezana nemiphumela emibi engavamile kodwa ekhathazayo edinga ukunakekelwa kwezokwelapha. Lokhu kufaka phakathi ukusabela okukhulu komzimba, ukopha okungavamile noma ukulimala, izinguquko ezinkulu zemizwa, noma imicabango yokuzilimaza. Nakuba kungavamile, le miphumela emibi ebucayi idinga ukuhlolwa kwezokwelapha ngokushesha.

Imiphumela emibi yezocansi, nakuba ingavamile nge-vilazodone kunezinye izidambisi zokucindezeleka, ingase yenzeke kwabanye abantu. Lokhu kungase kuhlanganise ukwehla kwesifiso sobulili, ubunzima bokufinyelela i-orgasm, noma ukungasebenzi kahle kwe-erectile emadodeni. Uma uhlangabezana nale miphumela, khuluma nodokotela wakho mayelana nezixazululo ezingenzeka.

Ubani Ongafanele Athatha I-Vilazodone?

I-Vilazodone ayiphephile kuwo wonke umuntu, futhi kunezimo eziningana ezibalulekile lapho kufanele igwenywe noma isetshenziswe ngokuqapha okukhulu. Ungalokothi uthathe i-vilazodone uma njengamanje uthatha noma usanda kuyeka ukuthatha ama-MAOI (ama-monoamine oxidase inhibitors), njengoba le nhlanganisela ingabangela isimo esiyingozi esibizwa ngokuthi i-serotonin syndrome.

Abantu abanezimo ezithile zezokwelapha badinga ukucatshangelwa okukhethekile ngaphambi kokuqala i-vilazodone. Uma unesifo esibi sesibindi noma sezinso, udokotela wakho angase adinge ukulungisa umthamo wakho noma akhethe umuthi ohlukile. Labo abanomlando wokuphazamiseka kokopha, ukuquleka, noma ukuphazamiseka kwe-bipolar nabo badinga ukuqapha ngokucophelela.

Abantu abadala abangaphansi kweminyaka engu-25 ubudala badinga ukuqapha okuseduze, njengoba izidambisi zokucindezeleka ngezinye izikhathi zingakhuphula imicabango yokuzibulala kulolu hlu lweminyaka phakathi nezinyanga zokuqala zokwelashwa. Abesifazane abakhulelwe noma abancelisa ngamabele kufanele baxoxe ngezingozi nezinzuzo nomhlinzeki wabo wokunakekelwa kwezempilo, njengoba i-vilazodone ingadlulela enganeni.

Uma usebenzisa ama-blood thinners, ama-NSAID, noma eminye imithi ethinta amazinga e-serotonin, udokotela wakho uzodinga ukucabangela ngokucophelela ukusebenzisana okungenzeka ngaphambi kokunquma i-vilazodone.

Igama Lomkhiqizo le-Vilazodone

I-Vilazodone ivame ukwaziwa ngegama layo lomkhiqizo elithi Viibryd, elenziwa yi-Allergan (manje eliyingxenye ye-AbbVie). Leli yigama lomkhiqizo lokuqala lapho imithi yaqala ukugunyazwa yi-FDA ngo-2011. Ungase ukubone lokhu kubhalwe njengokuthi

I-Vilazodone ne-sertraline yomibili imithi yokucindezela engcono, kodwa isebenza ngendlela ehlukile futhi inezinhlobo ezihlukene zemiphumela emibi. Akukho noyedwa othi ngokuqinisekile "ungcono" kunomunye - ukukhetha okungcono kuncike ezidingweni zakho kanye nokuthi umzimba wakho usabela kanjani emuthini ngamunye.

I-Vilazodone ingase ibe nenzuzo uma kuziwa emiphumeleni emibi yezocansi, njengoba izifundo zikhomba ukuthi mancane amathuba okuthi idale izinkinga ngomsebenzi wezocansi uma kuqhathaniswa ne-sertraline. Kodwa-ke, i-sertraline isinesikhathi eside ikhona futhi inocwaningo oluningi olusekela ukusetshenziswa kwayo ezimweni ezihlukahlukene ezingaphezu kokucindezeleka, okuhlanganisa izifo zokukhathazeka kanye ne-OCD.

I-Sertraline iyatholakala futhi njengomuthi ojwayelekile futhi ivame ukuba ngentengo ephansi kune-vilazodone. Abanye abantu bathola ukuthi i-sertraline kulula ukuyithatha ngoba ayidingi ukudla ukuze imuncwe kahle, kuyilapho i-vilazodone kumele ithathwe nokudla okukhulu. Udokotela wakho angakusiza ukuthi ulinganise lezi zinto ukuze unqume ukuthi yimuphi umuthi ongaba ukukhetha okungcono esimweni sakho esithile.

Imibuzo Evame Ukubuzwa Mayelana ne-Vilazodone

Ingabe i-Vilazodone iphephile ezigulini zenhliziyo?

I-Vilazodone ngokuvamile ithathwa njengephephile kubantu abanezifo zenhliziyo, kodwa idinga ukuqapha okucophelelayo. Ngokungafani neminye imithi yokucindezeleka endala, i-vilazodone ngokuvamile ayibangeli izinguquko ezinkulu ekushayeni kwenhliziyo noma umfutho wegazi. Kodwa-ke, ingasebenzisana nemithi yokunciphisa igazi, okuyilokho iziguli eziningi zenhliziyo ezikuthathayo.

Uma unesifo senhliziyo, udokotela wakho cishe uzoqala ngomthamo ophansi futhi akuqaphe eduze. Bazobuye babuyekeze yonke imithi yakho yenhliziyo ukuze bahlole ukuthi akukho yini ukusebenzisana okungenzeka. Abantu abaningi abanezifo zenhliziyo ezinzile bangayithatha ngokuphepha i-vilazodone, kodwa lesi sinqumo kufanele senziwe ngaso sonke isikhathi nodokotela wakho wenhliziyo kanye nodokotela wengqondo besebenzisana.

Ngingenzani uma ngiphuzile i-Vilazodone eningi ngengozi?

Uma ngabe uthatha umthamo omningi we-vilazodone kunalowo odokotela wakho abakuyale wona, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela izimpawu ezinjengokucasuka okukhulu, ukuhlanza, isiyezi, ukushaya kwenhliziyo okusheshayo, noma ukudideka. Ezimweni ezinzima, kungaholela ku-serotonin syndrome, edinga ukwelashwa okuphuthumayo.

Ungalindi ukubona ukuthi ngabe izimpawu ziyavela yini - kungcono ukuthola iseluleko sezokwelapha ngokushesha. Uma uhlangabezana nezimpawu ezinzima ezinjengobunzima bokuphefumula, ubuhlungu besifuba, noma ukulahlekelwa ukwazi, shayela izinsiza eziphuthumayo ngokushesha. Gcina ibhodlela lemithi nawe ukuze ochwepheshe bezokwelapha bakwazi ukubona kahle ukuthi yini nokuthi ungakanani oyithathile.

Kufanele Ngenzeni Uma Ngeqe Umthamo We-Vilazodone?

Uma weqa umthamo we-vilazodone, yithathe ngokushesha lapho ukhumbula, kodwa kuphela uma ungayithatha nokudla. Uma sekuseduze isikhathi somthamo wakho olandelayo (ngaphakathi kwamahora angu-4-6), weqa umthamo owuqeqile bese uqhubeka neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngasikhathi sinye ukuze ulungise umthamo owuqeqile.

Ukuqeqesha imithamo ngezikhathi ezithile ngeke kubangele izinkinga ezinkulu, kodwa zama ukugcina ukuthatha nsuku zonke okuqhubekayo ukuze uthole imiphumela engcono kakhulu. Uma uvame ukukhohlwa imithamo, cabanga ukusetha i-alamu yansuku zonke noma usebenzise umhleli wamaphilisi. Abanye abantu bakuthola kusiza ukuthatha i-vilazodone yabo ngesidlo esifanayo nsuku zonke ukuze bakhe isimiso.

Ngingayeka Nini Ukuthatha I-Vilazodone?

Kufanele uyeke kuphela ukuthatha i-vilazodone ngaphansi kwesiqondiso sikadokotela wakho, ngisho noma uzizwa ungcono kakhulu. Abantu abaningi badinga ukuqhubeka nokwelashwa okungenani izinyanga eziyi-6 kuya kweziyi-12 ngemuva kokuthi izimpawu zabo zithuthuke ukuvimbela ukuthi ukucindezeleka kungabuyi. Ukuyeka ngokushesha kakhulu kwandisa kakhulu ubungozi bokuphindeka.

Uma wena nodokotela wakho nithatha isinqumo sokuthi sekuyisikhathi sokuyeka, uzonciphisa kancane kancane umthamo emasontweni amaningana kunokuyeka kungazelelwe. Le nqubo yokunciphisa isiza ekuvikeleni izimpawu zokuhoxisa njengokugajeka, isicanucanu, ukucasuka, noma izinguquko zemizwa. Isheduli eqondile yokunciphisa incike ekutheni usithathe isikhathi esingakanani umuthi kanye nokuphendula kwakho ngakunye.

Ngingakwazi Ukuphuza Utywala Ngenkathi Ngithatha i-Vilazodone?

Kungcono ukugwema utshwala noma ukulunciphisa kakhulu ngenkathi uthatha i-vilazodone. Utshwala bungenza izimpawu zokucindezeleka zibe zimbi futhi bungase landise ingozi yemiphumela emibi efana nokugajeka, ukozela, noma ubunzima bokugxilisa ingqondo. Inhlanganisela ingase futhi yonakalise ukwahlulela kwakho nokuxhumana kwakho ngaphezu kwento eyodwa.

Uma ukhetha ukuphuza ngezikhathi ezithile, zilinganisele esiphuzweni esisodwa bese ubona ukuthi uzizwa kanjani. Abanye abantu bathola ukuthi bazwela kakhulu utshwala ngenkathi bethatha i-vilazodone. Ungalokothi usebenzise utshwala ukubhekana nezimpawu zokucindezeleka, ngoba lokhu kungaphazamisa ukwelashwa kwakho futhi kungaholela ekusebenzelaneni okuyingozi nemithi yakho.