Yini i-Vortioxetine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Vortioxetine iyimithi yokucindezela ebekelwe ngudokotela esiza ukwelapha ukucindezeleka okukhulu kubantu abadala. Ingokwesigaba esisha sezidakamizwa ezilwa nokucindezeleka ezisebenza ngendlela ehlukile kunezidakamizwa ezindala ngokugxila kumakhemikhali obuchopho amaningi ngesikhathi esisodwa.

Le mithi inikeza ithemba kubantu abangatholanga ukukhululeka ngezinye izidakamizwa ezilwa nokucindezeleka. Odokotela abaningi bayibheka njengenketho ebalulekile ngoba ingase ibangele imiphumela emincane yezocansi uma iqhathaniswa neminye imithi yokucindezeleka.

Yini i-Vortioxetine?

I-Vortioxetine iyimithi yesimanje elwa nokucindezeleka engase ibhalwe ngudokotela wakho uma ubhekene nokucindezeleka okukhulu. Yilokho ochwepheshe bezokwelapha abakubiza ngokuthi

Ngenkathi i-vortioxetine isetshenziselwa ukucindezeleka, abanye ochwepheshe bezempilo bangayinqumela ezinye izimo "ngaphandle kwemvume". Kodwa-ke, kufanele uyithathe kuphela ngezimo udokotela wakho azincomayo ngqo.

Isebenza Kanjani I-Vortioxetine?

I-Vortioxetine isebenza ngokuthinta amakhemikhali amaningi obuchopho athinta imizwa yakho nokucabanga kwakho. Ithathwa njenge-antidepressant enamandla aphakathi nendawo ethatha indlela eyingqayizivele yokwelapha ukucindezeleka.

Umuthi wenyusa amazinga e-serotonin ebuchosheni bakho, okusiza ukuthuthukisa imizwa nokulinganisela kwemizwa. Ngesikhathi esifanayo, ithinta ezinye izinhlelo ze-neurotransmitter ezilawula ukuthi amaseli obuchopho axhumana kanjani.

Le ndlela yokuhlasela izinto eziningi ingase isize ukuchaza ukuthi kungani abanye abantu besabela kahle ku-vortioxetine ngisho nalapho ezinye izidakamizwa ezingama-antidepressant zingasebenzi. Umuthi ngokuvamile uthatha amasonto amaningana ukukhombisa izinzuzo zawo ezigcwele, ngakho ukubekezela kubalulekile ngesikhathi sokuqala sokwelashwa.

Ngingayithatha Kanjani I-Vortioxetine?

Thatha i-vortioxetine ngendlela udokotela wakho ayinqume ngayo, ngokuvamile kanye ngosuku ngesikhathi esifanayo nsuku zonke. Ungayithatha ngokudla noma ngaphandle kokudla, nakuba ukuyithatha ngokudla kungasiza ukunciphisa isisu uma uhlangabezana nanoma yini.

Gwinya ithebhulethi yonke ngenkomishi yamanzi. Ungayichobozi, ungayiqhekezi, noma ungayihlafuni ithebhulethi, ngoba lokhu kungathinta ukuthi umuthi usebenza kanjani emzimbeni wakho.

Uma ukhohlwa umthamo, yithathe ngokushesha lapho ukhumbula ngalo lolo suku. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, weqa umthamo owuphuthelwe bese uqhubeka nohlelo lwakho olujwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo owuphuthelwe.

Kubalulekile ukuqhubeka nokuthatha i-vortioxetine ngisho noma uqala ukuzizwa ungcono. Imithi yokucindezeleka isebenza kahle uma ithathwa ngokuqhubekayo, futhi ukuyeka kungazelelwe kungabangela izimpawu zokuhoxiswa.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Vortioxetine?

Abantu abaningi badinga ukuthatha i-vortioxetine okungenani izinyanga eziyi-6 kuya kweziyi-12 ngemuva kokuba izimpawu zabo zokucindezeleka zithuthuke. Udokotela wakho uzosebenza nawe ukunquma ubude obufanele ngokuya ngesimo sakho somuntu ngamunye nokuthi usabela kanjani ekwelashweni.

Umuthi ngokuvamile uthatha amasonto ama-2 kuya kwama-4 ukuze uqale ukubonisa izinzuzo eziqashelwayo, nakuba abanye abantu bengase badinge amasonto angafika kwayi-6 kuya kwayi-8 ukuzwa imiphumela ephelele. Lesi sikhathi sokulinda singazizwa siyinselele, kodwa kujwayelekile ngokuphelele ukuthi ama-antidepressants athathe isikhathi ukusebenza.

Kwabanye abantu, ikakhulukazi labo abake baba neziqephu eziningi zokucindezeleka, ukwelashwa kwesikhathi eside kungase kunconywe. Umhlinzeki wakho wezempilo uzobuyekeza njalo inqubekela phambili yakho futhi alungise uhlelo lwakho lokwelashwa njengoba kudingeka.

Lapho sekuyisikhathi sokuyeka ukuthatha i-vortioxetine, udokotela wakho uzokwehlisa kancane kancane umthamo wakho emasontweni amaningana. Lokhu kusiza ukuvimbela izimpawu zokuhoxiswa futhi kuqinisekisa ukuguquka okubushelelezi ngaphandle komuthi.

Yiziphi Izimo Ezingezinhle Ze-Vortioxetine?

Njengayo yonke imithi, i-vortioxetine ingabangela imiphumela engemihle, nakuba kungewona wonke umuntu oyizwayo. Imiphumela eminingi emibi imild kuya kwemaphakathi futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala.

Nawa amanye imiphumela emibi evame kakhulu ongase uyizwe:

• Isicanucanu (lokhu kuyisimo esingezinhle esivame kakhulu)
• Ukuqunjelwa noma ukuqunjelwa
• Umlomo owomile
• Isiyezi noma ukuzwa ukukhathala
• Amaphupho angavamile noma izinguquko zokulala
• Isikhumba esilumayo
• Igesi noma ukuphatheka kabi kwesisu

Le miphumela emibi ejwayelekile ivame ukuba ngaphansi kokukhathaza njengoba umzimba wakho ujwayela umuthi. Ukuthatha i-vortioxetine nokudla kungasiza ukunciphisa isicanucanu kubantu abaningi.

Abanye abantu bangase babe nemiphumela emibi engavamile kodwa ekhathazayo edinga ukunakekelwa kwezempilo:

• Ukuphendula okukhulu komzimba (ukuqubuka, ukuvuvukala, ubunzima bokuphefumula)
• Ukuphuma kwegazi okungavamile noma ukulimala
• Iziqephu ze-manic (ushintsho olukhulu lwemizwa, imicabango egijimayo, ukwehla kwesidingo sokulala)
• I-Serotonin syndrome (ukudideka, umkhuhlane, ukushaya kwenhliziyo okusheshayo, ukuqina kwemisipha)
• Imicabango yokuzibulala, ikakhulukazi kubantu abadala abangaphansi kweminyaka engu-25
• Isiyezi esikhulu noma ukuquleka
• Izinkinga zamehlo njenge-angle-closure glaucoma

Nakuba lezi zinkinga ezingathi sína ezingemihle zivame kakhulu, kubalulekile ukuxhumana nomhlinzeki wakho wezempilo ngokushesha uma uhlangabezana nanoma yiziphi zazo. Ukuphepha kwakho kuyinto eza kuqala ekwelashweni kokucindezeleka.

Ubani Ongafanele Athole I-Vortioxetine?

I-Vortioxetine ayifanele wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Akufanele uthathe lo muthi uma unokungezwani komzimba ne-vortioxetine noma yiziphi izithako zawo.

Kunezimo eziningana ezibalulekile lapho i-vortioxetine idinga ukuqapha okukhethekile noma ingase inganconywa:

• Uma uthatha noma usanda kuthatha ama-MAO inhibitors (uhlobo lwe-antidepressant)
• Uma unomlando wokuphazamiseka kokopha noma uthatha imithi yokunciphisa igazi
• Uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa
• Uma unezifo ezinzima zezinso noma zesibindi
• Uma ungangaphansi kweminyaka engu-18 (ukuphepha akukamiswanga ezinganeni)
• Uma unomlando weziqephu ze-manic noma ze-hypomanic
• Uma une-narrow-angle glaucoma

Udokotela wakho uzophinda aqaphele kakhulu uma uneminyaka engaphezu kwengu-65, njengoba abadala bengase bazwe kalula imiphumela yomuthi. Hlala utshela umhlinzeki wakho wezempilo ngayo yonke imithi, izithasiselo, nezimo zezempilo ngaphambi kokuqala i-vortioxetine.

Amagama Omkhiqizo we-Vortioxetine

I-Vortioxetine itholakala ngaphansi kwegama lomkhiqizo elithi Trintellix e-United States. Le yindlela evame kakhulu ozoyibona ngayo i-odwa futhi inikezwe emakhemisi.

Umuthi wawuthengiswa ngaphambilini ngaphansi kwegama lomkhiqizo elithi Brintellix, kodwa lokhu kwashintshwa kwaba yi-Trintellix ngonyaka ka-2016 ukuze kugwenywe ukudideka nomunye umuthi. Uma unezibhodlela zemithi endala noma imininingwane, ungase usabona igama langaphambili.

Izinhlobo ezivamile ze-vortioxetine zingase zitholakale esikhathini esizayo, kodwa njengamanje, i-Trintellix iyigama eliyinhloko elitholakala emazweni amaningi lapho umuthi uvunyelwe khona.

Ezinye izindlela ze-Vortioxetine

Uma i-vortioxetine ingasebenzi kahle kuwe noma ibangela imiphumela engathandeki, zikhona ezinye izinketho zokulwa nokucindezeleka udokotela wakho angazicabangela. Umuntu ngamunye usabela ngendlela ehlukile emithini yokucindezeleka, ngakho-ke ukuthola okufanele ngezinye izikhathi kuthatha ukubekezela.

Ezinye izindlela zokulwa nokucindezeleka ezintsha ezisebenza ngendlela efanayo zihlanganisa:

• Vilazodone (Viibryd) - enye i-antidepressant ye-multimodal
• Levomilnacipran (Fetzima) - i-antidepressant ye-SNRI
• Desvenlafaxine (Pristiq) - enye inketho ye-SNRI

Ezinye izindlela ezisungulwe kakhulu zihlanganisa ama-SSRI afana ne-sertraline (Zoloft), i-escitalopram (Lexapro), kanye ne-fluoxetine (Prozac). Udokotela wakho angase futhi acabangele ama-SNRI afana ne-venlafaxine (Effexor) noma i-duloxetine (Cymbalta).

Ukukhetha enye indlela kuncike ezimpawini zakho ezithile, umlando wakho wezokwelapha, eminye imithi oyithathayo, kanye nezintandokazi zakho. Umhlinzeki wakho wezempilo uzosebenza nawe ukuthola inketho engcono kakhulu yesimo sakho.

Ingabe i-Vortioxetine ingcono kune-Sertraline?

I-Vortioxetine ne-sertraline (Zoloft) zombili ziyizindlela zokulwa nokucindezeleka ezisebenzayo, kodwa zisebenza ngendlela ehlukile futhi zinezinzuzo ezihlukile. Akukho noyedwa ovamile “ongcono” - ukukhetha okufanele kuncike ezidingweni zakho ngazinye nokuthi usabela kanjani emithini ngayinye.

IVortioxetine ingase ibe nezinzuzo ezithile ngaphezu kwe-sertraline kwabanye abantu. Ivame ukubangela imiphumela emibi engaphansi yezocansi, okungaba yinkinga enkulu nge-sertraline nezinye izi-SSRI. Ezinye izifundo nazo zikhomba ukuthi i-vortioxetine ingase ingabi nomthelela omkhulu ekuzuzeni isisindo.

Kodwa-ke, i-sertraline isetshenziswe ngempumelelo amashumi eminyaka futhi inesithombe sokuphepha esisungulwe kahle. Ivame ukuba ngentengo ephansi kune-vortioxetine futhi ingase imbozwe kangcono yizinhlelo zomshuwalense. I-Sertraline nayo ivunyelwe ezinye izimo ngaphandle kokucindezeleka, okuhlanganisa izifo zokukhathazeka.

Udokotela wakho uzocabangela izinto ezinjengamaphethini akho ezimpawu, okuhlangenwe nakho kwemithi yangaphambilini, imiphumela emibi engaba khona, nezindleko lapho ekusiza ukuthi ukhethe phakathi kwalezi zinketho. Ngezinye izikhathi ukuzama umuthi owodwa kuqala bese ushintsha uma kudingeka kuyindlela engcono kakhulu.

Imibuzo Evame Ukubuzwa Mayelana ne-Vortioxetine

Ingabe i-Vortioxetine Iphephile Ezigulini Zezifo Zenhliziyo?

I-Vortioxetine ngokuvamile ithathwa njengephephile kubantu abanezifo zenhliziyo, kodwa udokotela wakho uzodinga ukuhlola isimo sakho senhliziyo esithile. Umuthi ngokuvamile awubangeli izinkinga ezinkulu zesigqi senhliziyo noma izinguquko zomfutho wegazi kubantu abaningi.

Kodwa-ke, uma unezifo zenhliziyo ezinzima, umhlinzeki wakho wezempilo angase afune ukukuqapha eduze lapho uqala i-vortioxetine. Lokhu kubaluleke kakhulu uma uthatha eminye imithi engase ihlangane ne-vortioxetine noma uma unomlando wokungajwayelekile kwesigqi senhliziyo.

Njalo yazisa udokotela wakho nganoma yiziphi izinkinga zenhliziyo ngaphambi kokuqala lo muthi. Bangase batusa ukuqapha okwengeziwe noma bakhethe i-antidepressant ehlukile uma isimo sakho senhliziyo sibeka izingozi ezikhethekile.

Ngingenzani Uma Ngiphuzile i-Vortioxetine eningi ngengozi?

Uma ngabe uthathe i-vortioxetine eningi kunaleyo oyinikiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma uzizwa kahle. Ukuthatha okuningi kakhulu kungase kubangele imiphumela emibi, nakuba ukweqisa imithi akuvamile ukuba yingozi empilweni.

Izimpawu zokuthi kungenzeka ukuthi uthathe okuningi kakhulu zihlanganisa isicanucanu esibi, ukuhlanza, isiyezi, ukudideka, noma izinguquko ezingavamile ekushayeni kwenhliziyo. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, funa usizo lwezokwelapha ngokushesha.

Gcina ibhodlela lemithi unawo uma ufuna usizo, njengoba ochwepheshe bezokwelapha bazodinga ukwazi kahle ukuthi uthathe malini nokuthi nini. Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo ngumhlinzeki wezempilo.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Vortioxetine?

Uma uphuthelwa umthamo we-vortioxetine, yithathe ngokushesha lapho ukhumbula ngalo lolo suku. Uma ukhumbula ngesikhathi sokulala, usengayithatha umthamo ophuthelwe ngoba i-vortioxetine ngokuvamile ayibangeli izinkinga ezinkulu zokulala.

Nokho, uma sekuseduze nesikhathi somthamo wakho olandelayo noma usuvele ulale, weqa umthamo ophuthelwe bese uqhubeka nohlelo lwakho olujwayelekile ngosuku olulandelayo. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe.

Ukuphuthelwa umthamo ngezikhathi ezithile ngeke kukulimaze, kodwa zama ukugcina ukuthatha imithi nsuku zonke ukuze uthole imiphumela engcono kakhulu. Ukusetha isikhumbuzi sefoni noma ukuthatha imithi yakho ngesikhathi esifanayo nsuku zonke kungasiza ekuvimbeleni imithamo ephuthelwe.

Ngingayeka nini ukuthatha i-Vortioxetine?

Kufanele uyeke kuphela ukuthatha i-vortioxetine ngaphansi kwesiqondiso sikadokotela wakho, ngisho noma uzizwa ungcono kakhulu. Ukuyeka ama-antidepressants kungazelelwe kungabangela izimpawu zokuhoxiswa ezingakhululeki futhi kwandise ingozi yakho yokubuyela ekucindezelekeni.

Umhlinzeki wakho wezempilo ngokuvamile uzoncoma ukuqhubeka nokwelashwa okungenani izinyanga eziyi-6 kuya kweziyi-12 ngemuva kokuthi ukucindezeleka kwakho kuthuthuke. Kwabanye abantu, ikakhulukazi labo abanokucindezeleka okuphindaphindayo, ukwelashwa isikhathi eside kungase kube usizo.

Uma sekuyisikhathi sokuyeka, udokotela wakho uzokwenza isimiso sokunciphisa kancane kancane, anciphise kancane umthamo wakho emasontweni amaningana. Lokhu kusiza ukunciphisa izimpawu zokuhoxisa futhi kuqinisekisa ukushintsha okubushelelezi emuthini.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Vortioxetine?

Kungcono ukugwema utshwala noma ukulinciphisa kakhulu ngenkathi uthatha i-vortioxetine. Utshwala bungenza izimpawu zokucindezeleka zibe zimbi futhi zingakhuphula ingozi yemiphumela emibi efana nesiyezi, ukozela, nobunzima bokugxilisa ingqondo.

Ukuhlanganiswa kotshwala ne-vortioxetine kungase futhi kuphazamise ukwahlulela kwakho nokuxhumana kwakho ngaphezu kwanoma iyiphi into eyodwa. Lokhu kwandisa ingozi yezingozi, ukuwa, nezinye izinkinga zokuphepha.

Uma ukhetha ukuphuza ngezikhathi ezithile, yenza kanjalo ngokulinganisela kakhulu futhi unake indlela ozizwa ngayo. Khuluma nodokotela wakho mayelana nokusetshenziswa kotshwala - bangakunikeza isiqondiso esiqondene nawe esisekelwe esimweni sakho esithile futhi bakusize ukuthi wenze izinqumo eziphephe kakhulu zokululama kwempilo yakho yengqondo.