Yini i-Ziprasidone: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Ziprasidone iyimithi kadokotela esiza ukuphatha izimpawu ze-schizophrenia kanye ne-bipolar disorder. Ingaphansi kweqembu lemithi ebizwa ngokuthi ama-antipsychotics angajwayelekile, asebenza ngokulinganisela amakhemikhali athile ebuchosheni bakho ukunciphisa izimpawu ezinjengokucabanga, ukukhohlisa, nokushintshashintsha kwemizwa okukhulu.

Le mithi ingaba yithuluzi eliwusizo ohlelweni lwakho lokwelashwa kwempilo yengqondo. Ukuqonda ukuthi isebenza kanjani, okungakulindela, nokuthi uyithatha kanjani ngokuphepha kuzokusiza ukuthi wenze izinqumo ezinolwazi nomhlinzeki wakho wezempilo.

Yini i-Ziprasidone?

I-Ziprasidone iyimithi ye-antipsychotic engajwayelekile esiza ukubuyisela ukulinganisela kumakhemikhali obuchopho abizwa ngokuthi ama-neurotransmitters. Lawa makhemikhali athwala imilayezo phakathi kwamaseli obuchopho, futhi lapho engalingani, kungabangela izimpawu zezimo zempilo yengqondo.

Ngokungafani nemithi ye-antipsychotic endala, i-ziprasidone ithathwa njenge-

Udktela wakho angase futhi akunikeze i-ziprasidone ngezinye izimo ezingashiwanga lapha. Lokhu kubizwa ngokuthi ukusetshenziswa "okungahlelekile", futhi kuyindlela ejwayelekile uma abahlinzeki bezempilo bekholelwa ukuthi umuthi ungasiza ngokuya ngesimo sakho esithile nomlando wezokwelapha.

Isebenza Kanjani I-Ziprasidone?

I-Ziprasidone isebenza ngokuvimba ama-receptors athile ebuchosheni bakho athola imiyalezo yamakhemikhali. Ithonya ikakhulukazi i-dopamine ne-serotonin, amakhemikhali amabili obuchopho abalulekile athonya imizwa, imicabango, nokuziphatha.

Cabanga ngala makhemikhali obuchopho njengabathwali beposi abathumela imiyalezo phakathi kwezingxenye ezihlukene zobuchopho bakho. Uma kuningi kakhulu noma kuncane kakhulu kula makhemikhali, imiyalezo iyaxubana, okubangela izimpawu zokugula ngengqondo.

I-Ziprasidone ithathwa njengomuthi olinganiselwe onamandla wokulwa nokucindezeleka. Akuyona inketho enamandla kakhulu etholakalayo, kodwa isebenza ngokwanele ukuphatha izimpawu ezinzima zengqondo ngenkathi ngokuvamile kulula ukuzibekezelela kunezinye izidakamizwa ezindala.

Umuthi awelaphi ukugula ngengqondo, kodwa usiza ukuphatha izimpawu ukuze ukwazi ukusebenza kangcono ekuphileni kwansuku zonke. Abantu abaningi baqala ukuqaphela ukuthuthuka phakathi namasonto ambalwa, nakuba kungase kuthathe izinyanga eziningana ukuzwa izinzuzo eziphelele.

Kufanele Ngiyithathe Kanjani I-Ziprasidone?

Njalo thatha i-ziprasidone ngendlela udokotela wakho ayikuyala ngayo. Umuthi uza ngama-capsules owagwinya wonke ngamanzi. Ungalokothi uchoboze, uhlafune, noma uvule ama-capsules, njengoba lokhu kungathinta ukuthi umuthi usebenza kanjani.

Kubaluleke kakhulu ukuthatha i-ziprasidone ngokudla. Ukuyithatha esiswini esingenalutho kunganciphisa ukuthi umzimba wakho umunca kangakanani umuthi ngama-50%. Ukudla okungenani ngamakhalori angu-500 kusiza umzimba wakho ukuba umunce umuthi ngendlela efanele.

Zama ukuthatha imithamo yakho ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo ohlelweni lwakho. Uma uyithatha kabili ngosuku, hlukanisa imithamo cishe ngamahora angu-12. Ukusetha izikhumbuzi zocingo noma ukusebenzisa umhleli wamaphilisi kungakusiza ukuthi ukhumbule.

Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho ngamasu angase akusize. Ungazami ukuvula noma ukuchoboza amaphilisi ngokwakho, ngoba lokhu kungaba yingozi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Ziprasidone?

Ubude bokwelashwa nge-ziprasidone buhlukahluka kakhulu kumuntu nomuntu. Abanye abantu bangase bayidinge izinyanga eziningana, kanti abanye bangayithatha iminyaka noma isikhathi eside njengengxenye yokuphathwa kwabo okuqhubekayo kwempilo yengqondo.

Udokotela wakho uzohlola njalo ukuthi umuthi usebenza kahle kangakanani nokuthi usawudinga yini. Bazocabangela izinto ezinjengokulawulwa kwezimpawu zakho, ukusebenza konke, kanye nanoma yimaphi imiphumela emibi oyitholayo.

Ungayeki ukuthatha i-ziprasidone ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxiswa futhi kungaholela ekubuyeleni kwezimpawu zakho zokuqala. Uma udinga ukuyeka, udokotela wakho uzokwenza uhlelo lokunciphisa kancane kancane umthamo wakho.

Abanye abantu bakhathazeka ngokuthatha imithi yezifo zengqondo isikhathi eside, kodwa khumbula ukuthi izimo zempilo yengqondo ziyizimo zezokwelapha ezivame ukudinga ukwelashwa okuqhubekayo, njengoba kunjalo ngesifo sikashukela noma umfutho wegazi ophezulu.

Yiziphi Imiphumela Emibi Ye-Ziprasidone?

Njengayo yonke imithi, i-ziprasidone ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi imild kuya kwemaphakathi futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala.

Ake sibheke imiphumela emibi evame kakhulu ongase uyithole, sikhumbula ukuthi abantu abaningi bayawuthola kahle lo muthi:

• Ukozela noma ukuzizwa ulele emini
• Isiyezi, ikakhulukazi uma usukuma ngokushesha
• Isicanucanu noma isisu esibuhlungu
• Ukuqunjelwa noma izinguquko zokugaya ukudla
• Ikhanda
• Ukuqina kwemisipha noma ukungazinzi
• Ukukhuluphala, nakuba ngokuvamile kungaphansi kunamanye ama-antipsychotics
• Umlomo owomile
• Umbono ongacacile
• Ukhwehlela noma izimpawu ezifana nomkhuhlane

Lezi zimo ezivamile ezibangelwa imithi zivame ukulawuleka futhi zivame ukuncipha ngokuhamba kwesikhathi. Amasu alula afana nokuhlala unamanzi, ukudla ukudla okunothile ngama-fiber, nokuvuka kancane kungasiza ngeziningi zalezi zimo.

Kukhona futhi ezinye izimo ezingavamile kodwa ezingathi sína ezidinga ukunakekelwa kwezempilo ngokushesha. Nakuba lezi zinto zingavamile, kubalulekile ukuzazi:

• Ukuqina kwemisipha okukhulu okuhambisana nomkhuhlane nokudideka (i-neuroleptic malignant syndrome)
• Ukuhamba kwemisipha okungalawuleki, ikakhulukazi ebusweni bakho noma olimini
• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Isiyezi esikhulu noma ukuquleka
• Umkhuhlane ophezulu nokujuluka nokudideka
• Ukuhlaselwa
• Ukungezwani komzimba okukhulu okunezinduna, ukuvuvukala, noma ubunzima bokuphefumula
• Imicabango yokuzilimaza, ikakhulukazi kubantu abangaphansi kweminyaka engu-25
• Ukuvuka okude, okubuhlungu (emadodeni)
• Ushintsho olukhulu emazingeni kashukela egazini

Uma uhlangabezana nanoma yiziphi zalezi zimo ezingathi sína, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezempilo eziphuthumayo. Lezi zimo azivamile, kodwa zidinga ukwelashwa ngokushesha uma zenzeka.

Ubani Ongafanele Athathwe I-Ziprasidone?

I-Ziprasidone ayifanele wonke umuntu. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha nezimo zakho zamanje zempilo ngaphambi kokuyinika ukuze aqinisekise ukuthi iphephile kuwe.

Akufanele uthathe i-ziprasidone uma unezimo ezithile zenhliziyo, ikakhulukazi lezo ezithinta ukushaya kwenhliziyo yakho. Umuthi ungabangela izinguquko emisebenzini kagesi yenhliziyo yakho, okungaba yingozi kubantu abanezinkinga zenhliziyo ezikhona.

Abantu abanomlando we-QT interval ende (ukungajwayeleki kokushaya kwenhliziyo) kufanele bagweme i-ziprasidone. Udokotela wakho angase ayalele i-electrocardiogram (EKG) ngaphambi kokuqala umuthi ukuze ahlolisise ukushaya kwenhliziyo yakho.

Uma unenkinga yokungezwani komzimba ne-ziprasidone noma yiziphi izithako zayo, akufanele usebenzise lo muthi. Xhumana nodokotela wakho mayelana nanoma yiziphi izindlela zokungezwani komzimba nezidakamizwa, ikakhulukazi ezinye izidakamizwa ze-antipsychotics.

Ukuqapha okukhethekile kuyadingeka kubantu abadala abaneminyaka yobudala abanezifo ezinzima ezihlobene ne-dementia. I-Ziprasidone neminye imithi ye-antipsychotic ingandisa ingozi yezinkinga ezingathí sina kulaba bantu.

Udokotela wakho uzobheka nezinye izinto ezifana nokukhulelwa, ukuncelisa, izinkinga zezinso noma zesibindi, neminye imithi oyithathayo ngaphambi kokunquma i-ziprasidone.

Amagama Omkhiqizo we-Ziprasidone

I-Ziprasidone itholakala ngaphansi kwegama lomkhiqizo elithi Geodon e-United States. Lolu uhlobo lomkhiqizo oluvame ukunqunywa kakhulu.

Izinhlobo ze-generic ze-ziprasidone nazo ziyatholakala, eziqukethe isithako esifanayo esisebenzayo njenge-Geodon kodwa ngokuvamile zibiza kancane. Zombili izinhlobo zomkhiqizo ne-generic zisebenza ngendlela efanayo futhi zinesiphumo esifanayo.

Umthwebuli wakho wemithi angase athathele indawo uhlobo olujwayelekile ngaphandle uma udokotela wakho ebhalela ngqo ukuthi "igama lomkhiqizo kuphela" emiyalweni yakho. Uma unokukhathazeka ngokushintsha phakathi kwezinhlobo zomkhiqizo ne-generic, xoxa ngalokhu nomhlinzeki wakho wezempilo.

Ezinye Izindlela ze-Ziprasidone

Uma i-ziprasidone ingakulungele, kunezinye izidakamizwa eziningana ezingajwayelekile ze-antipsychotic udokotela wakho angazicabangela. Ngayinye inezinzuzo zayo nemiphumela engaba khona.

Ezinye izindlela ezivamile zihlanganisa i-risperidone (Risperdal), i-olanzapine (Zyprexa), i-quetiapine (Seroquel), ne-aripiprazole (Abilify). Udokotela wakho uzokhetha inketho engcono kakhulu ngokusekelwe ezimpawini zakho ezithile, umlando wezokwelapha, nokuthi usabele kanjani kweminye imithi.

Abanye abantu benza ngcono nge-antipsychotics endala, ejwayelekile njenge-haloperidol, nakuba lezi zivame ukubangela imiphumela eminingi ehlobene nokunyakaza. Abanye bangazuza kuma-mood stabilizers noma ezinye izinhlobo zemithi yezifo zengqondo.

Ukukhethwa komuthi kunqunywa ngumuntu ngamunye. Okusebenzela kahle omunye umuntu kungase kungasebenzi kahle komunye, ngakho-ke ukuthola umuthi ofanele ngokuvamile kudinga ukubekezela nokubambisana eduze nodokotela wakho.

Ingabe i-Ziprasidone ingcono kune-Olanzapine?

I-Ziprasidone ne-olanzapine (Zyprexa) yomibili imithi elwa nokucindezeleka engajwayelekile esebenzayo, kodwa inamandla ahlukene kanye nemiphumela emibi. Akukho noyedwa ongcono kunomunye - kuya ngezidingo zakho kanye nendlela ozosabela ngayo emuthini ngamunye.

I-Ziprasidone ngokuvamile ibangela ukukhuluphala okuncane kune-olanzapine, okungaba yinto ebalulekile okufanele icatshangelwe empilweni yesikhathi eside. Futhi ivame ukuba nomthelela omncane emazingeni kashukela wegazi ne-cholesterol, okuyenza ibe yindlela engcono kubantu abanesifo sikashukela noma izinkinga ze-metabolic.

Nokho, i-olanzapine ingase isebenze kangcono ezimpawini zabanye abantu, ikakhulukazi ekuvikeleni izigameko zemizwa ekuphazamisekeni kwe-bipolar. Itholakala futhi ngamafomu amaningi, okuhlanganisa ithebhulethi encibilikayo kanye nomjovo osebenza isikhathi eside.

Udokotela wakho uzocabangela izinto ezifana nephathini yakho yezimpawu, ezinye izimo zempilo, izimpendulo zemithi yangaphambilini, kanye nezintandokazi zakho siqu lapho ekhetha phakathi kwale mithi. Umuthi ongcono kakhulu kuwe yilowo olawula ngempumelelo izimpawu zakho ngemiphumela emibi embalwa.

Imibuzo Evame Ukubuzwa Mayelana ne-Ziprasidone

Q1. Ingabe i-Ziprasidone iphephile kubantu abanesifo sikashukela?

I-Ziprasidone ingasetshenziswa kubantu abanesifo sikashukela, kodwa idinga ukuqapha okucophelelayo. Umuthi ungathinta amazinga kashukela wegazi, nakuba uvame ukuba nomthelela omncane ku-glucose ne-insulin kunezinye izidakamizwa eziphikisana nokucindezeleka njenge-olanzapine.

Udokotela wakho cishe uzoqapha ushukela wakho wegazi kaningi lapho uqala i-ziprasidone, ikakhulukazi uma usuvele unesifo sikashukela noma usengozini yokusithuthukisa. Bangase futhi bahlole amazinga akho e-A1C ngezikhathi ezithile ukuze balandelele ukulawulwa koshukela wegazi wesikhathi eside.

Uma unesifo sikashukela, qhubeka nokulandela uhlelo lwakho lokuphatha isifo sikashukela ngenkathi usebenzisa i-ziprasidone. Bika noma yiziphi izimpawu ezingavamile njengokoma okukhulu, ukuchama njalo, noma ukukhathala okungachazeki kumhlinzeki wakho wezempilo ngokushesha.

Q2. Kufanele Ngenzeni Uma Ngisebenzisa I-Ziprasidone Engaphezu Kwemithamo Ngengozi?

Uma ngengozi uthatha i-ziprasidone eningi kakhulu, xhumana nodokotela wakho, isikhungo sokulawula ubuthi, noma izinsiza eziphuthumayo ngokushesha. Ungalindi ukubona ukuthi izimpawu ziyavela yini, njengoba ukweqisa kungaba kubi futhi kudinga ukunakekelwa kwezempilo okusheshayo.

Izimpawu zokweqisa i-ziprasidone zingabandakanya ukozela okukhulu, ukudideka, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, ukuqina kwemisipha, noma ukulahlekelwa ukwazi. Noma ngabe uzizwa ulungile, kubalulekile ukufuna ukuhlolwa kwezokwelapha ngemuva kokuthatha okuningi.

Ukuvimbela ukweqisa ngengozi, ungalokothi uthathe imithamo eyengeziwe ukuze "ukulungise" imithamo ephuthelwe, futhi ngaso sonke isikhathi sebenzisa umhleli wamaphilisi noma uhlelo lokukhumbuza imithi uma unzima ukukhumbula ukuthi ngabe uyithathile yini umthamo wakho.

Q3. Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Ziprasidone?

Uma uphuthelwa umthamo we-ziprasidone, yithathe ngokushesha lapho ukhumbula, kodwa kuphela uma ingasondeli ngesikhathi somthamo wakho olandelayo ohleliwe. Uma sekuseduze nesikhathi somthamo wakho olandelayo, weqa umthamo ophuthelwe bese uqhubeka nohlelo lwakho olujwayelekile.

Ungalokothi uthathe imithamo emibili ngasikhathi sinye ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma ungaqiniseki ngesikhathi, shayela ihhovisi likadokotela wakho noma ekhemisi ukuze uthole isiqondiso.

Ukuphuthelwa imithamo ngezikhathi ezithile akuyingozi, kodwa zama ukugcina amazinga aqhubekayo omuthi ohlelweni lwakho ukuze uthole ukulawulwa okungcono kakhulu kwezimpawu. Uma uvame ukukhohlwa imithamo, khuluma nodokotela wakho ngamasu okukusiza ukuthi ukhumbule.

Q4. Ngingayeka Nini Ukuthatha I-Ziprasidone?

Isinqumo sokuyeka i-ziprasidone kufanele senziwe ngaso sonke isikhathi ngokubambisana nodokotela wakho. Noma ngabe uzizwa ungcono kakhulu, ukuyeka kungazelelwe kungaholela ezimpawini zokuhoxisa kanye nokubuyela kwezimpawu zakho zokuqala.

Udokotela wakho uzocabangela izinto ezinjengokuthi usunesikhathi esingakanani uzinzile, ingozi yakho yokuphinda kwenzeke izimpawu, kanye nesimo sakho sempilo esiphelele lapho nixoxa ngokuthi kufanelekile yini ukunciphisa noma ukuyeka umuthi.

Uma wena nodokotela wakho ninquma ukuyeka i-ziprasidone, ngokuvamile uzonciphisa umthamo kancane kancane emasontweni amaningana noma izinyanga. Le nqubo yokunciphisa isiza ukunciphisa izimpawu zokuhoxisa futhi ivumela udokotela wakho ukuthi aqaphe noma yiziphi izimpawu ezibuyayo.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Ziprasidone?

Kungcono ukugwema utshwala ngenkathi uthatha i-ziprasidone noma ukulinciphisa kakhulu. Kokubili utshwala ne-ziprasidone kungabangela ukozela nesiyezi, futhi ukukuhlanganisa kungenza le miphumela ibe namandla kakhulu futhi ibe yingozi.

Utshwala bungaphazamisa nokusebenza komuthi futhi bungase lenze izimpawu zesimo sakho sempilo yengqondo zibe zimbi kakhulu. Uma ukhetha ukuphuza ngezikhathi ezithile, kwenze ngokulinganisela okukhulu futhi unake indlela ozizwa ngayo.

Njalo xoxa ngokusebenzisa utshwala nodokotela wakho. Bangakunikeza iseluleko esiqondene nawe esisekelwe esimweni sakho esithile, eminye imithi oyithathayo, kanye nesimo sakho sempilo esiphelele.