Yini i-Rheumatoid Factor? Inhloso, Amazinga & Nemiphumela

I-Rheumatoid factor iyilwanga olwenziwa amasosha omzimba wakho lapho ngempela ehlasela izicubu zakho ezinempilo. Cabanga ngayo njengohlelo lwakho lokuphepha lomzimba oludidekile futhi olwenza izikhali ngokumelene nawo. Lolu vivinyo legazi lusiza odokotela ukuthi baqonde ukuthi yini engase ibangele ubuhlungu emalungeni, ukuqina, noma ukuvuvukala okuhlangenwe nakho.

Yini i-rheumatoid factor?

I-Rheumatoid factor (RF) iyiphrotheni amasosha omzimba wakho ayikhiqizayo lapho ecabanga ukuthi izicubu zomzimba wakho zingabahlaseli bangaphandle. Ngokuvamile, ama-antibody akuvikela ezifweni nasezintweni eziyingozi. Nokho, ama-antibody e-RF aqondise amaprotheni akho anempilo, ikakhulukazi elilodwa elibizwa ngokuthi i-immunoglobulin G.

Lolu hlobo lokuzivikela emzimbeni lungenzeka ezimweni eziningana, hhayi nje i-rheumatoid arthritis. Umzimba wakho empeleni udidekile ngalokho okungokwakho nokungewakho. Ukuba khona kwe-RF egazini lakho kuphakamisa ukuthi amasosha omzimba wakho asebenza ngokweqile noma aqondiswe ngendlela engafanele.

Kubalulekile ukwazi ukuthi ukuba ne-RF akusho ngaso sonke isikhathi ukuthi une-rheumatoid arthritis. Abantu abaningi abane-RF abalokothi babe nezinkinga emalungeni, kanti abanye abantu abane-rheumatoid arthritis banamazinga e-RF avamile.

Kungani kwenziwa ukuhlolwa kwe-rheumatoid factor?

Odokotela ba-oda ukuhlolwa kwe-RF uma unezimpawu ezisikisela isimo sokuzivikela emzimbeni esithinta amalunga akho noma ezinye izitho. Isizathu esivame kakhulu ukusiza ukuxilonga i-rheumatoid arthritis, ikakhulukazi uma unobuhlungu obuqhubekayo emalungeni, ukuqina ekuseni, noma ukuvuvukala emalungeni amaningi.

Udokotela wakho angase futhi asebenzise lolu vivinyo ukuqapha ukuthi ukwelashwa kwakho kusebenza kahle kangakanani uma usuvele unesimo sokuzivikela emzimbeni. Amazinga e-RF angashintsha ngokuhamba kwesikhathi, futhi ukulandela lezi zinguquko kusiza ekuqondiseni izinqumo zokwelapha.

Ngesinye isikhathi ukuhlolwa kwe-RF kuyingxenye yokuhlolwa okubanzi uma unokukhathala okungachazeki, umkhuhlane, noma ezinye izimpawu ezingabonisa inqubo ye-autoimmune. Lolu vivinyo lunikeza ucezu olulodwa lwephazili yokuxilonga, kanye nezimpawu zakho, ukuhlolwa komzimba, kanye nokunye ukuhlolwa kwegazi.

Yini inqubo yokuhlolwa kwe-rheumatoid factor?

Ukuhlolwa kwe-RF kuyindlela elula yokudonsa igazi ethatha imizuzu embalwa nje. Uchwepheshe wezempilo uzohlanza ingalo yakho nge-antiseptic bese efaka inaliti encane emthanjeni, ngokuvamile endaweni yakho yesikhuphu. Uzozwa ukugwaza okusheshayo lapho inaliti ingena.

Isampula legazi liya ethubeni elincane bese lithunyelwa elabhorethri ukuze lihlaziwe. Yonke inqubo iqondile futhi inobungozi obuncane. Abantu abaningi bangabuyela emisebenzini yabo ejwayelekile ngokushesha ngemva kwalokho.

Ungase uzwe ukulimala okuncane noma ubumnene endaweni yenaliti, kodwa lokhu kuvame ukuxazululwa ngosuku olulodwa noma ezimbili. Izinkinga ezinzima ezivela ekudonseni igazi azivamile kakhulu.

Ungalungiselela kanjani ukuhlolwa kwakho kwe-rheumatoid factor?

Akukho ukulungiselela okukhethekile okudingekayo ekuhlolweni kwe-RF. Ungadla ngokujwayelekile ngaphambi kokuhlolwa futhi uthathe imithi yakho ejwayelekile ngaphandle uma udokotela wakho ekutshela ngokuqondile ngenye indlela. Lokhu kwenza kube lula ukulingana esimisweni sakho esijwayelekile.

Nokho, kuyasiza ukutshela udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa imithi etholakala ngaphandle kwekhawunta kanye nezithasiselo. Eminye imithi ingase ikwazi ukuthinta ukuhlolwa kwesistimu yokuzivikela komzimba, nakuba lokhu kungavamile ekuhlolweni kwe-RF.

Gqoka izingubo ezikhululekile ezinemikhono engasongwa kalula. Ukuhlala unamanzi ngaphambi kokuhlolwa kungenza kube lula kumhlinzeki wezempilo ukuthola umthambo omuhle wokudonsa igazi.

Ungawafunda kanjani imiphumela yakho ye-rheumatoid factor?

Imiphumela ye-RF ngokuvamile ibikwa njengenombolo enezinhlawo zokubhekisela ezihluka kancane phakathi kwamalebhu. Ngokuvamile, amazinga angaphansi kwama-20 amayunithi omhlaba wonke ngemililitha (IU/mL) abhekwa njengavamile, kuyilapho amazinga angaphezu kwalesi sikhawu abonisa ukuba khona kwe-rheumatoid factor.

Amazinga aphezulu e-RF akusho ngempela ukuthi isifo sibi kakhulu. Abanye abantu abanamazinga aphezulu kakhulu e-RF banezimpawu ezithambile, kanti abanye abanamazinga aphakeme ngokulinganiselwe bahlangabezana nezinkinga ezinkulu zamalunga. Udokotela wakho uhumusha le miphumela kanye nezimpawu zakho neminye imiphumela yokuhlolwa.

Isikhathi semiphumela yakho nayo ibalulekile. Amazinga e-RF angashintshashintsha, futhi ukuhlolwa okukodwa kunikeza nje isithombe esisheshayo. Udokotela wakho angase ancome ukuhlolwa okuphindwayo noma umsebenzi wegazi owengeziwe ukuze uthole umbono ocacile wokuthi kwenzakalani emzimbeni wakho.

Ungawaphatha kanjani amazinga angavamile e-rheumatoid factor?

Uma amazinga akho e-RF ephakeme, indlela incike ekutheni ngabe unezimpawu yini nokuthi yisiphi isimo esingase sibangele ukuphakama. Nge-rheumatoid arthritis, ukwelashwa ngokuvamile kugxila ekulawuleni ukuvuvukala nokuvikela amalunga akho ekulimaleni.

Udokotela wakho angase anqume imithi ethulisa amasosha akho omzimba asebenzayo ngokweqile, njengemithi elungisa isifo se-antirheumatic (DMARDs) noma i-biologics. Lokhu kwelashwa kungasiza ukunciphisa amazinga e-RF ngokuhamba kwesikhathi ngenkathi kuthuthukisa izimpawu zakho futhi kuvimbela ukulimala kwamalunga.

Ushintsho lwendlela yokuphila lungasekela ukwelashwa kwakho. Ukuzivocavoca umzimba njalo ngobumnene kusiza ukugcina ukuguquguquka kwamalunga namandla emisipha. Ukudla okulinganiselayo okucebile ngokudla okulwa nokuvuvukala kungasiza ukunciphisa ukuvuvukala okujwayelekile emzimbeni wakho.

Liyini izinga elingcono kakhulu le-rheumatoid factor?

Izinga elingcono kakhulu le-RF ngokuvamile lingaphansi kwama-20 IU/mL, okubhekwa njengohlu olujwayelekile lwamalebhu amaningi. Kodwa-ke,

Kufanele kuqashelwe ukuthi abanye abantu abanempilo ngokwemvelo banamazinga e-RF aphakeme kancane ngaphandle kwesifo. Ubudala bungathonya namazinga e-RF, ngabantu abadala ngezinye izikhathi bekhombisa amazinga aphezulu ngisho nalapho benempilo.

Udokotela wakho ugxila kakhulu ezinqeni ngokuhamba kwesikhathi kunanombolo eyodwa. Uma amazinga akho e-RF ezinzile futhi uzizwa kahle, lokhu kuvamile ukududuza ngisho noma izinombolo zingahambisani kahle nebanga eliqondiswayo.

Yiziphi izici eziyingozi ze-rheumatoid factor ephakeme?

Izici eziningana zingakhuphula amathuba akho okuba namazinga e-RF aphakeme, futhi ukuqonda lokhu kungakusiza wena nodokotela wakho ukuthi nihumushe imiphumela yakho ngokunembile.

Nazi izici eziyingozi okufanele uzazi:

• Umlando womndeni we-rheumatoid arthritis noma ezinye izimo ze-autoimmune
• Ukuba ngowesifazane (abesifazane maningi amathuba okuthi bathuthukise izimo ze-RF-positive)
• Ubudala obungaphezu kweminyaka engama-65 (amazinga e-RF angakhuphuka ngokwemvelo ngokuguga)
• Ukubhema noma umlando wokubhema
• Ezinye izifo, ikakhulukazi izifo zamagciwane ezingapheli noma ezithathelwanayo
• Ezinye izimo ze-autoimmune ezifana ne-lupus noma i-Sjögren's syndrome
• Izimo ezingapheli zokuvuvukala ezithinta isibindi noma amaphaphu

Ukuba nalezi zici eziyingozi akusho ukuthi nakanjani uzothuthukisa amazinga e-RF aphakeme noma i-rheumatoid arthritis. Abantu abaningi abanezici eziyingozi eziningi abalokothi bathuthukise lezi zimo, kuyilapho abanye abantu abangenazo izici eziyingozi ezibonakalayo benza.

Ingabe kungcono ukuba namazinga aphezulu noma aphansi e-rheumatoid factor?

Amazinga e-RF aphansi ngokuvamile angcono empilweni yakho. Amazinga e-RF avamile noma aphansi asikisela ukuthi amasosha akho omzimba awenzi ama-antibody ngokumelene nezicubu zakho, okunciphisa ingozi yokulimala kwamalunga okuhlobene ne-autoimmune kanye nezinye izinkinga.

Amazinga aphezulu e-RF abonisa ukwanda komsebenzi we-autoimmune, okungaholela ekuvuvukeni okungamahlalakhona kanye nokulimala kwezicubu ngokuhamba kwesikhathi. Kodwa-ke, ubuhlobo abuhlali buqondile - abanye abantu aban amazinga aphezulu e-RF bahlala benempilo iminyaka.

Okubaluleke kakhulu ukuthi amazinga akho e-RF ahlobene kanjani nezimpawu zakho kanye nesithombe sempilo yakho esiphelele. Udokotela wakho ucabangela imiphumela ye-RF kanye nokuhlolwa kwakho komzimba, izimpawu, kanye nokunye ukuhlolwa kwegazi ukuze anqume ukuthi ngabe ukwelashwa kuyadingeka yini.

Ziyini izinkinga ezingaba khona ze-rheumatoid factor ephansi?

Ukuba namazinga aphansi noma ajwayelekile e-RF ngokuvamile akuhlobene nezinkinga. Eqinisweni, amazinga aphansi e-RF yilokho esithemba ukukubona kubantu abanempilo. Lokhu kusikisela ukuthi amasosha akho omzimba asebenza ngendlela ejwayelekile futhi awahlaseli izicubu zakho.

Kodwa-ke, kubalulekile ukuqonda ukuthi abanye abantu abane-rheumatoid arthritis banamazinga ajwayelekile e-RF - lokhu kubizwa nge-seronegative rheumatoid arthritis. Uma unezimpawu zamalunga kodwa amazinga ajwayelekile e-RF, udokotela wakho angase ayale ukuhlolwa okwengeziwe ukuze akhiphe ezinye izinhlobo ze-arthritis.

Amazinga aphansi e-RF akuvikeli ekuthuthukiseni ezinye izinhlobo zezinkinga zamalunga noma izimo ze-autoimmune. Udokotela wakho uzocabangela isithombe sakho somtholampilo esiphelele, hhayi nje imiphumela yakho ye-RF, lapho uhlola impilo yakho.

Ziyini izinkinga ezingaba khona ze-rheumatoid factor ephezulu?

Amazinga e-RF aphakeme angahlobana nezinkinga eziningana, ikakhulukazi uma eyinxenye yesimo se-autoimmune esisebenzayo njenge-rheumatoid arthritis. Ukuqonda lezi zinto ezingenzeka kukusiza ukuthi usebenze nodokotela wakho ukuze uzivikele noma uziphathe ngempumelelo.

Izinkinga ezivame kakhulu zihlanganisa ukulimala kwamalunga nokukhubazeka uma ukuvuvukala kungalawulwa. Ukuhlasela kwamasosha akho omzimba ezicutshini zamalunga kungabhidliza kancane kancane i-cartilage nethambo, okuholela ebuhlungu, ukuqina, nokulahlekelwa umsebenzi.

Nawa amanye ama-complications angaba khona okufanele uwaqaphele:

• Izinkinga zenhliziyo nemithambo yegazi (ingozi yesifo senhliziyo iphakeme ngokuqubuka kokuvuvukala okungamahlalakhona)
• Izinkinga zamaphaphu, okuhlanganisa ukulimala noma ukuvuvukala kwezicubu zamaphaphu
• Izinkinga zamehlo njengokoma noma ukuvuvukala
• Ukwanda kwengozi yokutheleleka, ikakhulukazi uma uthatha imithi ecindezela amasosha omzimba
• Ukukhathala nokuncipha kwekhwalithi yempilo ngenxa yokuqubuka kokuvuvukala okungamahlalakhona
• I-Osteoporosis (ukuqina kwamathambo) ngenxa yokuqubuka kokuvuvukala okungamahlalakhona noma imithi ethile

Ukutholwa nokwelashwa kwasekuqaleni kunciphisa kakhulu ingozi yalezi zinkinga. Ukwelashwa kwesimanje kuphumelela kakhulu ekulawuleni ukuvuvukala nasekuvikeleni amalunga akho nezitho emonakalweni.

Kufanele ngibone nini udokotela ngezinkinga ze-rheumatoid factor?

Kufanele ubone udokotela uma uhlangabezana nobuhlungu obuqhubekayo emalungeni, ukuqina, noma ukuvuvukala okuthatha amasonto ambalwa. Ukuqina kwasekuseni okuthatha ngaphezu kwehora ukuthi kululame kuyakhathaza ikakhulukazi futhi kufanele kuhlolwe ngudokotela.

Ezinye izimpawu okufanele zibangele ukuvakashelwa kukadokotela zihlanganisa ukukhathala okungachazeki, imfiva ephansi, noma izinkinga zamalunga ezithinta amalunga amaningi ngokulinganayo (amalunga afanayo ezinhlangothini zombili zomzimba wakho). Lezi zindlela zingase zikhombe isimo se-autoimmune esidinga ukuhlolwa.

Uma usuvele wazi ukuthi unamazinga e-RF aphakeme, ukulandelela njalo nodokotela wakho kubalulekile ngisho noma uzizwa kahle. Ukwelashwa kwasekuqaleni kungavimbela izinkinga futhi kukusize ukuthi ugcine izinga elihle lempilo.

Imibuzo evame ukubuzwa mayelana ne-rheumatoid factor

Q.1 Ingabe ukuhlolwa kwe-rheumatoid factor kulungile ekuxilongeni i-rheumatoid arthritis?

Ukuhlolwa kwe-RF kuyasiza ekuxilongeni i-rheumatoid arthritis, kodwa akuphelele ngokwako. Cishe ama-70-80% abantu abane-rheumatoid arthritis banamazinga e-RF aphakeme, okusho ukuthi ama-20-30% anamazinga avamile naphezu kokuba nesimo. Ngaphezu kwalokho, abanye abantu abane-RF ephakeme abalokothi bathuthukise i-rheumatoid arthritis.

Udktora wakho usebenzisa imiphumela ye-RF kanye nezimpawu zakho, ukuhlolwa komzimba, kanye neminye imivivinyo yegazi ukuze enze ukuxilongwa. Inhlanganisela yokutholwa komtholampilo kanye nokuhlolwa kwelabhorethri inikeza isithombe esinembile kakhulu kunanoma yimuphi umvivinyo owodwa kuphela.

Q.2 Ingabe i-rheumatoid factor ephezulu ibangela ukulimala kwamalunga?

Amazinga aphezulu e-RF awabangeli ngqo ukulimala kwamalunga, kodwa abonisa ukuthi amasosha akho omzimba ahlasela izicubu zakho. Le nqubo ye-autoimmune idala ukuvuvukala okungapheli, okungase kulimaze kancane kancane amalunga uma kungelashwa.

Ukuvuvukala okubangelwa isimo esingaphansi kwe-autoimmune yikho okwenza ngempela ukulimala kwamalunga. I-RF ingumaki noma uphawu lwalolu hlelo kunokuba yimbangela eqondile yokulimala.

Q.3 Ingabe amazinga e-rheumatoid factor angashintsha ngokuhamba kwesikhathi?

Yebo, amazinga e-RF angashintshashintsha ngokuhamba kwesikhathi, ikakhulukazi ngemithi. Abantu abaningi babona amazinga abo e-RF ehla lapho isimo sabo se-autoimmune silawulwa kahle ngemithi. Kodwa-ke, abanye abantu bagcina amazinga aphakeme ngisho nalapho izimpawu zabo zithuthuka.

Udktora wakho angase aqaphe amazinga e-RF ngezikhathi ezithile ukuze alandelele ukuthi ukwelashwa kwakho kusebenza kahle kangakanani, kodwa ukuthuthuka kwezimpawu kanye nokutholwa kokuhlolwa komzimba kuvame ukubaluleka kakhulu kunenombolo eqondile ye-RF.

Q.4 Yiziphi ezinye izimo ezingabangela i-rheumatoid factor ephakeme?

Izimo eziningana ngaphandle kwe-rheumatoid arthritis zingabangela amazinga e-RF aphakeme. Lokhu kufaka phakathi ezinye izimo ze-autoimmune njenge-lupus, i-Sjögren's syndrome, kanye nesifo sezicubu ezixhunyiwe ezixubile. Izifo ezingapheli, isifo sesibindi, kanye nezimo ezithile zamaphaphu nazo zingakhuphula amazinga e-RF.

Abanye abadala abanempilo ngokwemvelo banamazinga e-RF aphakeme kancane ngaphandle kwanoma yisiphi isifo. Yingakho udktora wakho ecabangela izimpawu zakho neminye imiphumela yokuhlolwa kanye namazinga akho e-RF lapho enza ukuxilongwa.

Q.5 Ngingakhathazeka yini uma i-rheumatoid factor yami iphakeme kancane?

Izinga le-RF elinyuke kancane akudingeki ukuthi kube yisizathu sokukhathazeka ngokushesha, ikakhulukazi uma ungenazo izimpawu zobuhlungu emalungeni noma ezinye izifo ze-autoimmune. Abantu abaningi abanezinga le-RF elinyuke kancane abalokothi babe nezinkinga ezinkulu zempilo.

Noma kunjalo, kufanelekile ukuxoxa nodokotela wakho futhi mhlawumbe uqaphele ngokuhamba kwesikhathi. Uma uqala ukuba nezimpawu ezinjengobuhlungu obuqhubekayo emalungeni, ukuqina, noma ukuvuvukala, kuba kubaluleke kakhulu ukuthi uphenye ngokuqhubekayo ngezivivinyo ezengeziwe nokuhlolwa.