Yini i-Dasiglucagon: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Dasiglucagon iyimithi kadokotela esebenza njenge-hormone umzimba wakho owenza ngokwemvelo obizwa ngokuthi i-glucagon. Yenzelwe ngqo ukwelapha ushukela ophansi wegazi (i-hypoglycemia) kubantu abanesifo sikashukela lapho bengakwazi ukuthatha ushukela ngomlomo. Le mithi iza njengomjovo olungele ukusetshenziswa onganikezwa ngaphansi kwesikhumba ezimeni eziphuthumayo.

Yini i-Dasiglucagon?

I-Dasiglucagon iyinguqulo yokwenziwa ye-glucagon, i-hormone etshela isibindi sakho ukuthi sikhiphe ushukela ogciniwe ungene egazini lakho. Lapho othile onesifo sikashukela ethola ushukela wegazi ophansi ngendlela eyingozi futhi engazi lutho noma engakwazi ukugwinya, le mithi ingakwazi ukunyusa ngokushesha amazinga kashukela wegazi lakhe. Yenziwe ukuthi izinzile kune-glucagon yemvelo, okusho ukuthi akudingeki ixutshwe ngaphambi kokusetshenziswa.

Umuthi usebenza ngokubopha kuma-receptors afanayo esibindini sakho asetshenziswa yi-glucagon yemvelo. Lokhu kuqala isibindi sakho ukuthi sihlukanise i-glycogen egciniwe ibe yi-glucose, engena egazini lakho ukuze inyuse amazinga kashukela wegazi lakho. Cabanga ngayo njengesistimu yakho yokusekela esiphuthumayo yokuthola ushukela uma uwudinga kakhulu.

Isetshenziselwani i-Dasiglucagon?

I-Dasiglucagon iphatha i-hypoglycemia enzima kubantu abadala kanye nezingane ezineminyaka engu-6 ubudala nangaphezulu abanesifo sikashukela. Le mithi yenzelwe ngqo izimo eziphuthumayo lapho ushukela wegazi wehla kakhulu kangangokuthi umuntu akazi lutho, uba nokuhlaselwa yizifo, noma akakwazi ukugwinya uketshezi noma ukudla ngokuphepha. Ayihloselwe ukuphathwa kashukela wegazi kwansuku zonke.

Udokotela wakho angase akubhalele le mithi uma usengozini yezigameko ezinzima zoshukela wegazi ophansi. Abantu abathatha i-insulin noma imithi ethile yesifo sikashukela maningi amathuba okuthi bahlangabezane nalezi zinto eziyingozi zokwehla kukashukela wegazi. Ukuba ne-dasiglucagon etholakalayo kukunikeza wena namalungu omndeni wakho indlela yokusiza ngalezi zimo ezesabekayo.

Isebenza Kanjani i-Dasiglucagon?

I-Dasiglucagon ithathwa njengomuthi oqinile futhi osheshayo wezimo eziphuthumayo. Isebenza ngokulingisa i-hormone yakho yemvelo ye-glucagon, esebenza njengesignali esiphuthumayo esibindini sakho. Uma ujova i-dasiglucagon, iya kuma-receptors e-glucagon esibindini sakho futhi iwatshele ukuthi aqale ngokushesha ukwephula ushukela ogciniwe.

Ngemizuzu engama-15 ngemuva komjovo, isibindi sakho siqala ukukhipha i-glucose egazini lakho. Abantu abaningi babona ushukela wabo wegazi uqala ukukhuphuka ngaphakathi kwalesi sikhathi, nakuba kungathatha imizuzu engama-30 ukuze kube nomphumela ogcwele. Umuthi ngokuvamile uqhubeka usebenza cishe imizuzu engama-90, ukukunika isikhathi sokuthola usizo olwengeziwe noma ukudla okuthile ukuze ugcine ushukela wegazi uzinzile.

Ngingawuthatha Kanjani I-Dasiglucagon?

I-Dasiglucagon iza njengepeni elizaliswe ngaphambili noma isirinji elizaliswe ngaphambili olizovela ngaphansi kwesikhumba sethanga lakho noma ingalo engenhla. Akudingeki ukuthi udle lutho ngaphambi kokusebenzisa lo muthi ngoba usetshenziswa uma umuntu engakwazi ukudla noma ukuphuza ngokuphepha. Umjovo kufanele unikezwe ngokushesha ngangokunokwenzeka lapho umuntu enoshukela wegazi ophansi kakhulu.

Nakhu ukuthi inqubo yokujova ivamise ukusebenza kanjani. Okokuqala, susa ikepisi ephepheni bese ulibeka ngokuqinile endaweni yokujova. Cindezela inkinobho ukuze unikeze umthamo ogcwele, bese uyibamba endaweni cishe imizuzwana eyi-10. Ngemuva kokunikeza umjovo, shayela izinsiza eziphuthumayo ngokushesha futhi uhlale nomuntu kuze kube yilapho usizo lufika.

Gcina i-dasiglucagon yakho ekamelweni lokushisa kude nokukhanya nokushisa. Ungayifaki esiqandisini, futhi hlola usuku lokuphelelwa yisikhathi njalo. Qiniseka ukuthi amalungu omndeni, abangane, noma osebenza nabo bayazi ukuthi uyigcina kuphi nokuthi ungayisebenzisa kanjani esimweni esiphuthumayo.

Ngingayithatha Isikhathi Esingakanani I-Dasiglucagon?

I-Dasiglucagon isetshenziswa kuphela ezimweni eziphuthumayo, hhayi njengomuthi wansuku zonke. Umjovo ngamunye umthamo wesikhathi esisodwa onikezwa lapho umuntu enoshukela wegazi ophansi kakhulu. Awuthathi lo muthi ngeshejuli ejwayelekile njengeminye imithi yesifo sikashukela.

Ngemva kokusebenzisa i-dasiglucagon, umuntu kufanele adle ukudla noma ukudla okulula okuqukethe ama-carbohydrate uma esevukile futhi ekwazi ukugwinya ngokuphepha. Lokhu kusiza ukugcina amazinga kashukela egazini azinzile ngemuva kokuthi umuthi usuphelile. Udokotela wakho uzofuna ukubuyekeza okubangele isigameko esibi soshukela ophansi egazini ukusiza ekuvimbeleni izimo eziphuthumayo zesikhathi esizayo.

Yiziphi Imiphumela Eceleni Ye-Dasiglucagon?

Abantu abaningi bahlangabezana nemiphumela ethile engemihle ngemuva kokuthola i-dasiglucagon, futhi lokhu kujwayelekile ngokuphelele ngenxa yesimo esiphuthumayo sokusetshenziswa kwayo. Imiphumela engemihle evame kakhulu yenzeka ngoba umzimba wakho usabela kokubili ushukela ophansi egazini kanye nemiphumela yomuthi ohlelweni lwakho.

Imiphumela engemihle ejwayelekile ongase uyithole ihlanganisa:

• Isicanucanu nokuhlanza
• Ikhanda
• Ukuphendula endaweni yokujova njengobubomvu noma ubuhlungu
• Ukuzizwa ukhathele noma ubuthakathaka
• Isiyezi

Lezi zimpawu zivame ukuthuthuka emahoreni ambalwa njengoba ushukela wakho egazini uzinzisa futhi umzimba wakho ululama esimweni esiphuthumayo.

Imiphumela engemihle engavamile kodwa ebucayi ingahlanganisa ukusabela okukhulu komzimba, nakuba lokhu kungavamile. Izimpawu zokusabela okukhulu komzimba zihlanganisa ubunzima bokuphefumula, ukuvuvukala kobuso bakho noma umphimbo, noma ukuqubuka okukhulu. Uma ngabe yiziphi lezi zimpawu zenzeka, funa ukunakekelwa kwezempilo okuphuthumayo ngokushesha.

Abanye abantu bangase bahlangabezane namazinga kashukela egazini ashintshashintshayo aphezulu kakhulu ngemuva kokusebenzisa i-dasiglucagon. Lokhu kwenzeka ngoba umuthi ngezinye izikhathi ungase ulungise ngokweqile ushukela ophansi egazini. Ithimba lakho lokunakekelwa kwezempilo lizobheka amazinga kashukela wakho egazini futhi lilungise uhlelo lwakho lokuphatha isifo sikashukela uma kudingeka.

Ubani Ongafanele Athole I-Dasiglucagon?

I-Dasiglucagon ayifaneleki kuwo wonke umuntu, futhi zikhona izimo ezithile lapho ingafanele isetshenziswe khona. Abantu abanezimo ezithile zezokwelapha noma labo abathatha imithi ethile kungenzeka bangabi ngabazali abahle balokhu kwelashwa.

Akufanele usebenzise i-dasiglucagon uma une:

• Ukungezwani okwaziwayo ne-dasiglucagon noma yiziphi izithako zayo
• Umkhuhlane wendlala yamanyikwe obizwa nge-insulinoma
• Umkhuhlane wendlala ye-adrenal obizwa nge-pheochromocytoma

Lezi zimo zingenza i-dasiglucagon ibe yingozi ngoba ingase ibangele izinkinga ezinzima noma yenze izinkinga zezempilo ezikhona zibe zimbi kakhulu.

Xhumana nodokotela wakho mayelana nazo zonke izimo zakho zezempilo ngaphambi kokuthola incwadi kadokotela ye-dasiglucagon. Abantu abanezifo zenhliziyo, izinkinga zezinso, noma isifo sesibindi bangase badinge ukuqashwa okukhethekile. Udokotela wakho uzophinda afune ukwazi ngemithi oyithathayo, okuhlanganisa ama-blood thinners, ngoba i-dasiglucagon ingathinta indlela eminye imithi esebenza ngayo.

Abesifazane abakhulelwe noma abancelisa ngamabele kufanele baxoxe ngezingozi nezinzuzo nomhlinzeki wabo wezempilo. Ngenkathi i-dasiglucagon ingasetshenziswa ngesikhathi sokukhulelwa uma idingeka nge-hypoglycemia enzima, udokotela wakho uzofuna ukulinganisela ngokucophelela izinzuzo eziphuthumayo ngokumelene nanoma yiziphi izingozi ezingaba khona.

Amagama Omkhiqizo we-Dasiglucagon

I-Dasiglucagon ithengiswa ngaphansi kwegama lomkhiqizo elithi Zegalogue e-United States. Leli okwamanje yilona kuphela igama lomkhiqizo elitholakalayo kulolu hlobo oluthile lwe-glucagon. I-Zegalogue iza njengomjovo olungiselelwe ukusetshenziswa ongadingi ukuxutshwa, okwenza kube lula ukuyisebenzisa ezimweni eziphuthumayo.

Eminye imikhiqizo ye-glucagon ikhona ngamagama omkhiqizo ahlukene, kodwa inezindlela zokwakheka ezihlukene kanye nezidingo zokulungiselela. Inzuzo enkulu ye-Zegalogue ukuthi izinzile futhi isilungele ukusetshenziswa ngokushesha, ngokungafani nemikhiqizo endala ye-glucagon edinga ukuxutshwa ngaphambi komjovo.

Ezinye Izindlela Zokwelapha ze-Dasiglucagon

Ezinye izindlela zokwelapha eziphuthumayo ze-hypoglycemia enzima ziyatholakala uma i-dasiglucagon ingakulungele. Lezi zindlela zokwelapha zisebenza ngezindlela ezifanayo kodwa zingase zibe nezidingo ezihlukene zokulungiselela noma izindlela zokulethwa.

Udokotela wakho angase acabangele lezi zindlela zokwelapha:

• Umjovo we-Glucagon (ifomu lendabuko lempushana elidinga ukuxutshwa)
• Baqsimi (i-glucagon powder yasekhala)
• Gvoke (umjovo we-glucagon osetshenziswa ngokushesha)
• Proglycem (ezinhlotsheni ezithile ze-hypoglycemia)

Ngayinye yalezi zinketho inezinzuzo zayo kanye nezinto okufanele zicatshangelwe. Ezinye zidinga ukuxutshwa ngaphambi kokusetshenziswa, kanti ezinye zinikezwa ngekhala esikhundleni somjovo. Umhlinzeki wakho wezempilo uzokusiza ukhethe inketho engcono kakhulu ngokusekelwe ezidingweni zakho ezithile, indlela yokuphila, kanye nomlando wakho wezokwelapha.

Ingabe i-Dasiglucagon ingcono kune-Glucagon?

I-Dasiglucagon inikeza ezinye izinzuzo ngaphezu kwe-glucagon yendabuko, ikakhulukazi ezimeni eziphuthumayo. Inzuzo enkulu ukuthi i-dasiglucagon iza isilungele ukusetshenziswa, kuyilapho i-glucagon yendabuko idinga ukuxuba impushana noketshezi ngaphambi komjovo. Lokhu kungonga isikhathi esiyigugu ngesikhathi esiphuthumayo se-hypoglycemic.

I-Glucagon yendabuko isetshenziswe ngokuphepha amashumi eminyaka futhi isebenza kahle kakhulu ekuphakamiseni amazinga kashukela egazini. Kodwa-ke, isinyathelo sokuxuba singaba yinselelo kumalungu omndeni noma ababukeli abacindezelekile ngesikhathi esiphuthumayo. I-Dasiglucagon iqeda lesi sinyathelo, okwenza kube lula kubantu abangewona odokotela ukuthi bayinike.

Zombili lezi zithako zisebenza kahle ngokulinganayo ekuphakamiseni amazinga kashukela egazini futhi zinezinhlobo ezifanayo zemiphumela emibi. Ukukhetha phakathi kwazo kuvame ukwehla kalula, izindleko, kanye nokukhetha komuntu siqu. Abanye abantu bakhetha ukulula kwe-dasiglucagon, kanti abanye bazizwa bekhululekile nge-glucagon yendabuko futhi bangase bayithole ishibhile.

Imibuzo Evame Ukubuzwa Mayelana ne-Dasiglucagon

Ingabe i-Dasiglucagon iphephile ezigulini ezinokugula kwenhliziyo?

I-Dasiglucagon ingasetshenziswa kubantu abanokugula kwenhliziyo, kodwa idinga ukucatshangelwa ngokucophelela ngumhlinzeki wakho wezempilo. Umuthi ungathinta izinga lokushaya kwenhliziyo nomfutho wegazi, okungase kube ngukukhathazeka kubantu abanezimo ezithile zenhliziyo. Udokotela wakho uzohlola izinzuzo eziphuthumayo ngokumelene nanoma yizipho ezingaba khona zenhliziyo nemithambo yegazi.

Uma unesifo senhliziyo, qiniseka ukuthi udokotela wakho uyazi ngayo yonke imithi yakho yenhliziyo nezimo zakho. Bangase bafune ukunikeza imiyalelo ekhethekile emndenini wakho mayelana nokuthi bangashayela nini izinsiza eziphuthumayo ngemva kokunikeza umjovo. Izinzuzo zokusindisa impilo zokwelapha i-hypoglycemia eqinile ngokuvamile zidlula izingozi zenhliziyo nemithambo yegazi.

Kufanele ngenzeni uma ngisebenzisa i-Dasiglucagon eningi ngengozi?

Ukusebenzisa i-dasiglucagon eningi kungabangela ukuthi ushukela wakho wegazi unyuke kakhulu, okuholela ezimpawini ezinjengokoma ngokweqile, ukuchama njalo, noma isicanucanu. Uma ngengozi unikeza ngaphezu kwemithamo eyodwa, qapha amazinga kashukela wegazi ngokucophelela futhi uxhumane nomhlinzeki wakho wezempilo noma izinsiza eziphuthumayo ngokushesha.

Ungazami ukulungisa ushukela wegazi ophezulu nge-insulin eyengeziwe ngaphandle kwesiqondiso sezokwelapha. Imiphumela ye-dasiglucagon ingeyesikhashana, ngokuvamile ihlala cishe imizuzu engama-90, ngakho-ke ushukela wegazi ophezulu kufanele uthuthuke ngokwawo. Kodwa-ke, uzodinga ukugadwa kwezokwelapha ukuze uqinisekise ukuthi ushukela wakho wegazi ubuyela emazingeni aphephile ngaphandle kokushintsha phansi kakhulu futhi.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Dasiglucagon?

I-Dasiglucagon ayithathwa ngeshejuli ejwayelekile, ngakho-ke awukwazi ngempela

Kufanele ugcine i-dasiglucagon itholakala uma usengozini ye-hypoglycemia enkulu. Abantu abaningi abanesifo sikashukela abathatha i-insulin noma imithi ethile yesifo sikashukela bayazuza ekubeni ne-glucagon esheshayo etholakalayo kuyo yonke imithi yabo. Udokotela wakho uzokwazisa uma ukuphathwa kwesifo sikashukela sakho kushintsha ngokwanele ukuthi awusadingi i-glucagon esheshayo.

Ukuhlolwa njalo kwesifo sikashukela kubalulekile ekuhloleni ubungozi bakho be-hypoglycemia. Uma ungakabi nesiqephu esiphansi sikashukela esibi isikhathi eside futhi isifo sakho sikashukela silawulwa kahle, udokotela wakho angase axoxe ngokuthi usadinga yini ukuthwala i-glucagon esheshayo. Kodwa-ke, ochwepheshe bezempilo abaningi batusa ukuyigcina itholakala njengesinyathelo sokuphepha.

Ngingayisebenzisa i-Dasiglucagon uma ngingenawo isifo sikashukela?

I-Dasiglucagon igunyazwe ngokuqondile ukwelapha i-hypoglycemia enkulu kubantu abanesifo sikashukela. Uma ungenaso isifo sikashukela kodwa uhlangabezana noshukela ophansi kakhulu, udokotela wakho uzodinga ukuhlola imbangela eyisisekelo futhi anqume ukwelashwa okufanele kakhulu. I-hypoglycemia engeyona eyabantu abanesifo sikashukela ingaba nezimbangela ezahlukene ezingadinga ukwelashwa okuhlukile.

Ezinye izimo ezingavamile zezokwelapha zingabangela ushukela ophansi kakhulu kubantu abangenawo isifo sikashukela. Lezi zimo zidinga ukunakekelwa kwezokwelapha okukhethekile kanye nezindlela zokwelapha ezihlukene. Umhlinzeki wakho wezempilo uzosebenza nawe ukukhomba imbangela futhi athuthukise uhlelo olufanele oluphuthumayo uma kudingeka.