Yini i-Deflazacort: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Deflazacort iyimithi ye-corticosteroid esiza ukunciphisa ukuvuvukala futhi icindezele amasosha akho omzimba uma esebenza ngokweqile. Cabanga ngayo njengomzala omnene we-prednisone odokotela abavame ukuyikhetha ngoba ivame ukubangela imiphumela emincane eceleni, ikakhulu uma udinga ukuyithatha isikhathi eside.

Le mithi isebenza ngokulingisa i-cortisol, i-hormone umzimba wakho oyikhiqiza ngokwemvelo ukuze ulawule ukuvuvukala. Uma amasosha akho omzimba ehlasela izicubu ezinempilo noma ebangela ukuvuvukala ngokweqile, i-deflazacort ingena ukuze ithulise izinto futhi inike umzimba wakho impumuzo owuyidingayo.

Yini i-Deflazacort Esetshenziselwa Yona?

I-Deflazacort iphatha izinhlobonhlobo zezimo lapho ukuvuvukala kuyinkinga enkulu. Udokotela wakho angase akubhalele yona uma amasosha akho omzimba esabela ngokweqile noma uma izicubu emzimbeni wakho zivuvukele futhi zibangela ubuhlungu noma ukungasebenzi kahle.

Le mithi ilusizo ikakhulukazi ezimweni ze-autoimmune lapho umzimba wakho uhlasela ngamaphutha amaseli awo anempilo. Isetshenziswa futhi uma ezinye izingxenye zomzimba wakho zivuvukele ngenxa yokulimala, ukutheleleka, noma isifo esingamahlalakhona.

Nawa amanye amazwi i-deflazacort engasiza ukuphatha:

• I-Duchenne muscular dystrophy (DMD) - isiza ukugcina ukusebenza kwemisipha futhi yehlise ukuqhubeka
• I-Rheumatoid arthritis - inciphisa ukuvuvukala kwamalunga nobuhlungu
• Isifo samathumbu esivuvukalayo - sithulisa ukuvuvukala kwamathumbu
• I-Asthma nokusabela okukhulu komzimba - kuvula izindlela zomoya futhi kunciphisa ukuvuvukala
• I-Lupus nezinye izifo ze-autoimmune - ilawula ukusebenza ngokweqile kwamasosha omzimba
• Izimo zesikhumba njenge-eczema noma i-psoriasis enzima - inciphisa ukuvuvukala nokuluma
• Ezinye izifo zegazi - kuyasiza uma amasosha omzimba ehlasela amaseli egazi
• Ukuvimbela ukwenqatshwa kokufakelwa kwezitho - kugcina amasosha omzimba engahlaseli isitho esisha

Udktela wakho uzoqaphela ukuthi i-deflazacort ilungile yini esimweni sakho esithile ngokusekelwe ezimpawini zakho, umlando wakho wezokwelapha, nokuthi ezinye izindlela zokwelapha zikusebenzele kanjani.

Isebenza Kanjani I-Deflazacort?

I-Deflazacort isebenza ngokuvimba ukukhiqizwa kwezinto emzimbeni wakho ezibangela ukuvuvukala nokusabela komzimba. Ithathwa njenge-corticosteroid enamandla aphakathi nendawo, okusho ukuthi iyasebenza kodwa ngokuvamile ibangela imiphumela emibi embalwa kunezinketho ezinamandla njenge-prednisone.

Uma uthatha i-deflazacort, iguqulwa esibindini sakho ibe yifomu elisebenzayo elihamba emzimbeni wakho wonke. Leli fomu elisebenzayo libopha kuma-receptors akhethekile emangqamuzeni akho futhi liwatshela ukuthi ayeke ukukhiqiza amakhemikhali avuvukalayo njenge-prostaglandins kanye ne-leukotrienes.

Umuthi futhi ucindezela umsebenzi womzimba wakho wokuzivikela, okusiza uma umzimba wakho wokuzivikela usebenza ngokweqile kodwa kusho ukuthi ungase ube sengozini enkulu yokutheleleka ngenkathi uwuthatha. Lokhu kucindezelwa komzimba ngokuvamile kulula kuya phakathi nendawo uma kuqhathaniswa namanye ama-corticosteroids.

Kufanele Ngiyithathe Kanjani I-Deflazacort?

Thatha i-deflazacort ngendlela udokotela wakho ayala ngayo, ngokuvamile kanye ngosuku ekuseni ngokudla. Ukuyithatha nge-breakfast kusiza ukunciphisa isisu esicasulayo futhi ilingisa isigqi somzimba wakho esivamile se-cortisol, esifinyelela ezingeni eliphezulu ekuseni.

Ungathatha amaphilisi e-deflazacort wonke nengilazi yamanzi egcwele, noma ungaqeda futhi uxube nokudla okuthambile njenge-applesauce uma ukugwinya kunzima. Ukumiswa ngomlomo kufanele kunyakaziswe kahle ngaphambi kwesilinganiso ngasinye futhi kulinganiswe ngedivayisi yokulinganisa enikeziwe.

Zama ukuthatha umthamo wakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo emzimbeni wakho. Uma uyithatha ngesimo esifana nesifuba somoya, ukuqina kubaluleke kakhulu ekuvikeleni ukuqubuka.

Ungayithathi i-deflazacort esiswini esingenalutho ngoba lokhu kwandisa ingozi yokucasuka kwesisu. Ukudla okulula noma ukudla okulula kuvamile ukwanele, kodwa gwema ukuyithatha ngekhofi nje noma ijusi.

Ngizothatha isikhathi esingakanani i-Deflazacort?

Ubude bokwelashwa nge-deflazacort buqondene ngokuphelele nesimo sakho nokuthi usabela kanjani emuthini. Abanye abantu bayayidinga izinsuku ezimbalwa nje ngesikhathi sokugqashuka okukhulu, kanti abanye badinga ukwelashwa isikhathi eside ngezimo ezingamahlalakhona.

Ukusetshenziswa kwesikhashana (ngaphansi kwamasonto ama-2), ungase ukwazi ukuyeka umuthi ngokuphazima kweso lapho izimpawu zakho zithuthuka. Kodwa-ke, uma ubuthatha i-deflazacort isikhathi esingaphezu kwamasonto ama-2-3, udokotela wakho cishe uzokwenza ukuthi unciphise kancane kancane ukuze ugweme izimpawu zokuhoxisa.

Abantu abanezimo ezingamahlalakhona njenge-Duchenne muscular dystrophy noma izifo ezizimele ezinzima kungenzeka badinge ukuthatha i-deflazacort izinyanga noma iminyaka. Ezimweni ezinjalo, udokotela wakho uzokuhlola njalo ukuze abone imiphumela emibi futhi alungise umthamo wakho njengoba kudingeka.

Ungayeki ukuthatha i-deflazacort ngokuzumayo uma ubuthatha isikhathi esingaphezu kwamasonto ambalwa, ngoba lokhu kungabangela izimpawu zokuhoxisa eziyingozi. Udokotela wakho uzokwenza isimiso sokunciphisa esinciphisa kancane kancane umthamo wakho ngokuhamba kwesikhathi.

Yiziphi Imiphumela Emibi ye-Deflazacort?

Njengawo wonke ama-corticosteroids, i-deflazacort ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle, ikakhulukazi ngemithamo ephansi. Izindaba ezinhle ukuthi i-deflazacort ngokuvamile ibangela imiphumela emibi embalwa kunezinye izidakamizwa ze-corticosteroids njenge-prednisone.

Imiphumela emibi eminingi incike emthozini, okusho ukuthi imithamo ephezulu nezikhathi zokwelashwa ezinde zikhuphula ingozi yakho. Imiphumela eminingi emibi iyabuyiseka futhi uma uyeka umuthi noma unciphisa umthamo.

Nawa imiphumela emibi evame kakhulu ongase uyithole:

• Ukwanda kwesifiso sokudla nokukhuluphala - ikakhulukazi emzimbeni wakho naphambili ebusweni
• Ushintsho lwemizwa - uzizwa uthukuthele, ukhathazekile, noma unzima ukulala
• Ukwanda kwengozi yokutheleleka - amasosha akho omzimba ayacindezelwa
• Ukuphazamiseka kwesisu noma isilungulela - ukuthatha ngokudla kusiza ukuvimbela lokhu
• Ukukhathazeka kwekhanda noma isiyezi - ngokuvamile kulula futhi okwesikhashana
• Izinduna noma izinguquko zesikhumba - isikhumba sakho singancipha noma silimale kalula
• Ushukela ophezulu wegazi - kubalulekile ukuqapha uma unesifo sikashukela

Imiphumela emibi engathi sína ingenzeka ngokusebenzisa isikhathi eside noma imithamo ephezulu. Ngenkathi lokhu kungavamile, kubalulekile ukukwazi:

• Ukuncipha kwamathambo (i-osteoporosis) - ikakhulukazi okukhathazayo kubantu abadala
• Umfutho wegazi ophezulu - ukuqapha njalo kubalulekile
• Ama-cataracts noma i-glaucoma - izinkinga zamehlo ezithuthuka kancane kancane
• Ubuthakathaka bemisipha - buhlukile ebuthakathakeni obubangelwa isimo sakho esingaphansi
• Ukunqatshelwa kokuphulukiswa kwamanxeba - ukusikeka nokulimala kuthatha isikhathi eside ukuphola
• Ukuvinjelwa kokukhula ezinganeni - kungani imithamo yezingane iqashwe ngokucophelela

Xhumana nodokotela wakho ngokushesha uma uhlangabezana nezinguquko ezinzima zemizwa, izimpawu zokutheleleka njengomkhuhlane, izinkinga zombono, noma ubuhlungu obukhulu besisu. Lokhu kufanele kunakekelwe ngokushesha kwezokwelapha.

Ubani Ongafanele Athathwe I-Deflazacort?

I-Deflazacort ayiphephile kuwo wonke umuntu, futhi izimo ezithile zezokwelapha noma izimo zikwenza kungafaneleki noma zidinga izinyathelo zokuphepha ezikhethekile. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokunikeza lo muthi.

Akufanele uthathe i-deflazacort uma unezifo ezithile ezisebenzayo, ikakhulukazi izifo zama-fungal, njengoba umuthi ungacindezela amasosha akho omzimba futhi wenze izifo zibe zimbi. Imithi yokugoma ephilayo nayo ayivunyelwe ngenkathi uthatha i-deflazacort.

Nawa amanye amakhondishini angakuvimbela ukuthi ungathathi i-deflazacort noma adinge ukuqashwa okukhethekile:

• Izifo ezithathelwanayo ezisebenzayo - ikakhulukazi izifo zamafungi, amagciwane, noma amagciwane
• Ukungezwani okwaziwayo ne-deflazacort noma ezinye izidakamizwa ze-corticosteroids
• Ukugonywa kwamuva ngemithi yokugoma ephilayo - linda okungenani amasonto ama-2 ngemuva kokuyeka i-deflazacort
• Isifo sesibindi esibi - sithinta indlela umzimba wakho oqhubula ngayo imithi
• Izimo zamehlo ezithile njengezifo zamehlo ezinamagciwane noma amafungi

Izimo ezidinga ukuqapha okwengeziwe nokubheka zihlanganisa:

• Isifo sikashukela - i-deflazacort ingakhuphula amazinga kashukela egazini
• Umfutho wegazi ophezulu noma isifo senhliziyo - imithi ingenza lezi zimo zibe zimbi
• I-Osteoporosis noma umlando wokuphuka - ama-corticosteroids anganciphisa amathambo
• Izilonda zesisu noma izinkinga zokugaya ukudla - ingozi eyengeziwe yokopha
• Izimo zempilo yengqondo - ama-corticosteroids angathinta imizwa nokuziphatha
• Izinkinga zezinso noma zesibindi - kungadingeka ukulungiswa komthamo
• Ukukhulelwa noma ukuncelisa - kudinga ukuhlaziywa ngokucophelela kobungozi-nenzuzo

Uma unezinye zalezi zimo, udokotela wakho angase akwazi ukukuyala i-deflazacort kodwa uzokubheka eduze futhi mhlawumbe alungise umthamo wakho noma uhlelo lokwelashwa.

Amagama Omkhiqizo we-Deflazacort

I-Deflazacort iyatholakala ngaphansi kwamagama amaningi omkhiqizo, i-Emflaza iyona evame kakhulu e-United States. Le nguqulo yegama lomkhiqizo yavunywa ngqo yi-FDA yokwelapha i-Duchenne muscular dystrophy ngo-2017.

Amanye amagama omkhiqizo ongahlangana nawo afaka i-Calcort, evame ukusetshenziswa kwamanye amazwe. Amanye amakhemisi angase abe nezinguqulo ezivamile ze-deflazacort, ezinomuthi ofanayo osebenzayo kodwa zingase zibe ngentengo ephansi.

Noma ngabe igama lomkhiqizo linjani, yonke imithi ye-deflazacort isebenza ngendlela efanayo. Umkhemisi wakho angakusiza ukuthi uqonde ukuthi ngabe uthola igama lomkhiqizo noma inguqulo ejwayelekile, futhi udokotela wakho angakweluleka ukuthi ngabe umkhiqizo othile ukhethwa yini ngesimo sakho.

Ezinye izindlela ze-Deflazacort

Uma i-deflazacort ingakulungele noma ingasebenzi kahle, imithi eminingi ehlukile inganikeza imiphumela efanayo yokulwa nokuvuvukala kanye nokucindezela amasosha omzimba. Udokotela wakho uzokhetha ezinye izindlela ngokusekelwe esimweni sakho esithile kanye nomlando wakho wezokwelapha.

Ezinye izinhlobo ze-corticosteroids zihlanganisa i-prednisone, i-prednisolone, kanye ne-methylprednisolone. Lezi zisebenza ngendlela efana ne-deflazacort kodwa zingase zibe nemiphumela ehlukile noma amashejuli okulinganisa angahambisana kangcono nezidingo zakho.

Ezinye izindlela ezingezona i-corticosteroid zincike esimweni sakho esithile:

• Ezimweni ze-autoimmune - i-methotrexate, i-hydroxychloroquine, noma imithi emisha ye-biologic
• Ngesifo samathumbu esivuvukalayo - ama-aminosalicylates, ama-immunomodulators, noma imithi elwa ne-TNF
• Nge-asthma - ama-corticosteroids aphefumulwayo, ama-bronchodilators, noma ama-leukotriene modifiers
• Nge-rheumatoid arthritis - imithi yokuguqula isifo se-antirheumatic (DMARDs)
• Nge-muscular dystrophy - ezinye izinhlobo ze-corticosteroids noma izindlela zokwelapha ezivelayo

Udokotela wakho uzosebenza nawe ukuthola ukwelashwa okuphumelela kakhulu ngemiphumela emincane kakhulu eceleni yesimo sakho esithile.

Ingabe i-Deflazacort Ingcono Kune-Prednisone?

I-Deflazacort ne-prednisone zombili ziyizinhlobo ze-corticosteroids ezisebenzayo, kodwa i-deflazacort ivame ukuba nezinzuzo, ikakhulukazi ekusetshenzisweni kwesikhathi eside. Odokotela abaningi bakhetha i-deflazacort ngoba ivame ukubangela ukukhuluphala okuncane, ukulahlekelwa amathambo, kanye nokucindezelwa kokukhula ezinganeni.

Ucwaningo lubonisa ukuthi i-deflazacort ibangela umthelela omncane ekuqineni kwamathambo kanye nokukhula okungahambisani ne-prednisone ngemithamo elinganayo yokulwa nokuvuvukala. Lokhu kuyenza ibaluleke ikakhulukazi ezinganeni ezinemibandela efana ne-Duchenne muscular dystrophy ezidinga ukwelashwa kwe-corticosteroid yesikhathi eside.

I-Deflazacort ibonakala futhi inethonya elincane ekusebenzeni kwe-glucose, okusho ukuthi mancane amathuba okuthi ibangele isifo sikashukela noma yenze isifo sikashukela esikhona sibe sibi kune-prednisone. Ingozi yokuthuthukisa "ubuso benyanga" noma ukukhuluphala okumaphakathi nendawo ngokuvamile iphansi nge-deflazacort.

Kodwa-ke, i-prednisone isinesikhathi eside futhi ayibizi kakhulu kune-deflazacort. Ukuze isetshenziswe ngesikhathi esifushane noma uma izindleko ziyisici esikhulu, i-prednisone ingase ibe yindlela engcono. Udokotela wakho uzocabangela izidingo zakho ezithile, ubude bokwelashwa, kanye nesimo sezimali lapho ekhetha phakathi kwale mithi.

Imibuzo Evame Ukubuzwa Mayelana ne-Deflazacort

Ingabe i-Deflazacort iphephile ku-Diabetes?

I-Deflazacort ingasetshenziswa kubantu abanesifo sikashukela, kodwa idinga ukuqapha ngokucophelela futhi mhlawumbe ilungise imithi yakho yesifo sikashukela. Njengamanye ama-corticosteroids, i-deflazacort ingakhuphula amazinga kashukela egazini, nakuba ngokuvamile inethonya elincane ku-glucose kune-prednisone.

Uma unesifo sikashukela, udokotela wakho cishe uzofuna ukuhlola ushukela wakho wegazi kaningi lapho uqala i-deflazacort. Ungase udinge ukulungisa imithi yakho yesifo sikashukela noma imithamo ye-insulin okwesikhashana ngenkathi uthatha i-corticosteroid.

Abantu abanesifo sikashukela esilawulwa kahle bangakwazi ukuphuza i-deflazacort ngokuphepha ngokuqapha okufanele. Labo abanesifo sikashukela esingalawulwa kahle bangase badinge ukuthuthukisa ukulawulwa kwabo ushukela wegazi ngaphambi kokuqala i-deflazacort, noma basebenzise ezinye izindlela zokwelapha uma kungenzeka.

Ngingenzani Uma Ngiphuthelwa Ngokusebenzisa i-Deflazacort eningi kakhulu?

Uma ngempela uthatha i-deflazacort eningi kakhulu, xhumana nodokotela wakho noma ukulawulwa kwe-poison ngokushesha, ikakhulukazi uma uthathe okuningi kakhulu kunomthamo wakho obekiwe. Ukuthatha okuningi kungaholela ezimpawini ezinjengokushintsha okukhulu kwemizwa, ushukela wegazi ophezulu, noma umfutho wegazi owenyukile.

Umthamo owodwa owengeziwe akunakwenzeka ukuthi ubonakalise ukulimala okukhulu, kodwa ungaphindi umthamo wakho olandelayo ukuze ulungise. Kunalokho, buyela esimisweni sakho esijwayelekile sokuthatha imithi bese wazisa udokotela wakho ngaleli phutha ekuhlolweni kwakho okulandelayo.

Izimpawu zokweqisa umthamo zingabandakanya ukuguquguquka okukhulu kwemizwa, ukudideka, ikhanda elibuhlungu kakhulu, ukushaya kwenhliziyo okusheshayo, noma ubunzima bokulala. Uma uhlangabezana nanoma yiziphi zalezi zimpawu ngemva kokuthatha i-deflazacort eningi kakhulu, funa ukwelashwa ngokushesha.

Kufanele Ngenzeni Uma Ngeqe Umthamo We-Deflazacort?

Uma weqa umthamo we-deflazacort, yithathe ngokushesha lapho ukhumbula, ngaphandle kwalapho sekuyisikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo oweqiwe bese uqhubeka nesimiso sakho esijwayelekile - ungalokothi uthathe imithamo emibili ngesikhathi esisodwa.

Ukuze uthathe umthamo kanye ngosuku, ungafaka umthamo oweqiwe kuze kube amahora angu-12 sekwephuzile ngaphandle kokuthinta ukwelashwa kwakho ngokuphawulekayo. Uma sekudlule amahora angaphezu kwangu-12, ngokuvamile kungcono ukweqa lowo mthamo bese uthatha umthamo wakho olandelayo ngesikhathi esijwayelekile.

Uma uvame ukukhohlwa imithamo, cabanga ngokumisa i-alamu yefoni noma usebenzise umhleli wamaphilisi ukukusiza ukuthi ukhumbule. Ukuthatha imithi ngokuqhubekayo kubalulekile ekuphatheni isimo sakho ngempumelelo nasekuvikeleni ukuqubuka kwezimpawu.

Ngingayeka Nini Ukuthatha I-Deflazacort?

Ungayeka ukuthatha i-deflazacort lapho udokotela wakho enquma ukuthi kuphephile ukwenza kanjalo, okuncike esimweni sakho, ukuthi usithatha isikhathi esingakanani, kanye nomthamo wakho wamanje. Ungalokothi uyeke i-deflazacort ngokuzumayo uma ubusithatha isikhathi esingaphezu kwamasonto angu-2-3.

Ukusetshenziswa kwesikhashana (ngaphansi kwamasonto angu-2), ungase ukwazi ukuyeka kungazelelwe ngaphandle kwezinkinga. Nokho, ukusetshenziswa kwesikhathi eside kudinga isimiso sokunciphisa kancane ukuze kugwenywe izimpawu zokuhoxiswa njengokukhathala, ubuhlungu emalungeni, noma ukuqubuka kwesimo sakho esingaphansi.

Udktela wakho uzokwenza isimiso sokunciphisa kancane kancane umthamo wakho emasontweni noma ezinyangeni. Lokhu kuvumela umzimba wakho ukuthi ukhiqize i-cortisol ngokwemvelo futhi kuvimbela izimpawu eziyingozi zokuhoxisa. Landela lesi simiso ngqo, ngisho noma uzizwa ungcono.

Ngingayithatha i-Deflazacort ngesikhathi sokukhulelwa?

I-Deflazacort ngesikhathi sokukhulelwa idinga ukucatshangelwa ngokucophelela kwezinzuzo uma kuqhathaniswa nezingozi. Nakuba kungewona umuthi wokuqala ngesikhathi sokukhulelwa, kungase kudingeke ezimweni ezinzima lapho izinzuzo zidlula izingozi ezingase zibe khona kumama nomntwana.

Ama-corticosteroids afana ne-deflazacort angawela i-placenta futhi angase athinte ukukhula kombungu, ikakhulukazi uma esetshenziswa ngesikhathi sokukhulelwa kokuqala. Nokho, izimo ezingalawuleki zokuvuvukala nazo zingalimaza umama nomntwana, ngakho ukwelashwa ngezinye izikhathi kuyadingeka.

Uma uhlela ukukhulelwa noma uthola ukuthi ukhulelwe ngenkathi uthatha i-deflazacort, xoxa ngalokhu nodokotela wakho ngokushesha. Bangase balungise umthamo wakho, bashintshele emuthini ohlukile, noma baqhubeke ne-deflazacort uma kubalulekile empilweni yakho. Ukuqapha eduze ngesikhathi sokukhulelwa kuzodingeka.