Yini i-Desvenlafaxine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Desvenlafaxine iyisidambisi sokucindezeleka esinikezwa ngudokotela esisiza ukulinganisa amakhemikhali obuchopho ukuze kuthuthukiswe imizwa futhi kuncishiswe ukukhathazeka. Ingaphansi kohlu lwemithi ebizwa ngokuthi ama-serotonin-norepinephrine reuptake inhibitors (SNRIs), esebenza ngokwandisa amazinga e-neurotransmitters ezimbili ezibalulekile ebuchosheni bakho. Le mithi ivame ukunikezwa ngoba inkinga enkulu yokucindezeleka futhi ingaba yithuluzi eliphumelelayo ekuphatheni ukucindezeleka uma isetshenziswa njengengxenye yohlelo lokwelapha olubanzi.

Yini i-Desvenlafaxine?

I-Desvenlafaxine iyisidambisi sokucindezeleka esisebenza ngokuthinta amakhemikhali obuchopho ukusiza ukuphakamisa imizwa nokunciphisa izimpawu zokucindezeleka. Empeleni iyindlela esebenzayo yesinye isidambisi sokucindezeleka esibizwa ngokuthi i-venlafaxine, umzimba wakho owenza ngokwemvelo ube yi-desvenlafaxine uma usuyithathile.

Le mithi yathuthukiswa ukuze inikeze imiphumela evumelana kakhulu kuneyandulelayo. Uma uthatha i-desvenlafaxine, uthola isithako esisebenzayo ngokuqondile, esingaholela emiphumeleni elindeleke kakhulu. Itholakala njengepilisi ekhishwe isikhathi eside, okusho ukuthi imithi ikhishwa kancane kancane usuku lonke ukuze kugcinwe amazinga aqinile ohlelweni lwakho.

Le mithi ithathwa njengesidambisi sokucindezeleka sesimanje esivame ukubekezelelwa kahle ngabantu abaningi. Iye yahlolisiswa kabanzi futhi yavunywa yi-FDA ukwelapha ukucindezeleka kubantu abadala. Abahlinzeki bezempilo abaningi bakhetha ukunikeza i-desvenlafaxine ngoba ivame ukuba nokuxhumana okuncane kwemithi uma kuqhathaniswa nezinye izidambisi zokucindezeleka.

Isetshenziselwani i-Desvenlafaxine?

I-Desvenlafaxine ngokuyinhloko inikezwa ukwelapha inkinga enkulu yokucindezeleka, isimo sempilo yengqondo esibi esithinta indlela ozizwa ngayo, ocabanga ngayo, nokuphatha imisebenzi yansuku zonke. Udokotela wakho angase ancome le mithi uma ube nokudabuka okuqhubekayo, ukulahlekelwa intshisekelo emisebenzini, noma ezinye izimpawu zokucindezeleka okungenani amasonto amabili.

Ngaphandle kokusetshenziswa kwayo okuyinhloko kokucindezeleka, odokotela ngezinye izikhathi banikeza i-desvenlafaxine kwezinye izimo. Lokhu kungabandakanya izifo zokukhathazeka, ukuhlaselwa ukwethuka, noma izinhlobo ezithile zezimo zobuhlungu obungapheli. Kodwa-ke, lokhu kuthathwa njengokusebenzisa "ngaphandle kwelebula", okusho ukuthi akuyona isizathu esiyinhloko sokuthi umuthi wagunyazwa ekuqaleni.

Abanye abahlinzeki bezempilo bangase futhi bacabangele i-desvenlafaxine ekuphatheni ama-hot flashes kwabesifazane abase-menopausal, ikakhulukazi lapho ukwelashwa ngamahomoni kungafaneleki. Umuthi ungasiza ukunciphisa imvamisa nokuqina kwalezi ziqephu. Udokotela wakho uzoqaphela ngokucophelela ukuthi lo muthi ulungile yini esimweni sakho esithile nezimpawu.

Isebenza Kanjani I-Desvenlafaxine?

I-Desvenlafaxine isebenza ngokwandisa amazinga amakhemikhali amabili obuchopho abizwa ngokuthi i-serotonin ne-norepinephrine. Lawa ma-neurotransmitters adlala indima ebalulekile ekulawuleni imizwa, ukulala, ukudla, kanye nenhlalakahle yonke. Uma unokucindezeleka, lawa makhemikhali avame ukungalingani noma angasebenzi kahle.

Umuthi uvimbela ukuthathwa kabusha kwala ma-neurotransmitters, okusho ukuthi uvimbela ubuchopho bakho ukuthi buwasuse ngokushesha ezikhaleni eziphakathi kwamangqamuzana ezinzwa. Lokhu kuvumela i-serotonin ne-norepinephrine ukuthi zihlale zisebenza isikhathi eside, okusiza ukuthuthukisa ukuxhumana phakathi kwamangqamuzana obuchopho futhi kancane kancane kuphakamise imizwa yakho.

I-Desvenlafaxine ithathwa njenge-antidepressant enamandla ngokulinganisela. Inamandla kakhulu kunezinye izidakamizwa ezindala kodwa ngokuvamile inobungane kunezinye izidakamizwa zanamuhla. Imiphumela ngokuvamile yakheka phakathi namasonto amaningana, ngakho ungase ungaboni ngcono ngokushesha. Le nqubo enqanqanayo ijwayelekile futhi isiza ubuchopho bakho ukuthi bujwayele umuthi ngokuphepha.

Kufanele Ngiyithathe Kanjani I-Desvenlafaxine?

Thatha i-desvenlafaxine ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile kanye ngosuku ngesikhathi esifanayo nsuku zonke. Ungayithatha ngokudla noma ngaphandle kokudla, nakuba ukuyithatha ngokudla kungasiza ukunciphisa ukuquleka kwesisu uma kwenzeka. Gwinya ithebhulethi yonke ngenkomishi yamanzi egcwele, futhi ungayichobozi, uyihlafune, noma uyiphule ngoba yakhelwe ukuthi ikhiphe kancane.

Abantu abaningi bakuthola kuwusizo ukuthatha umthamo wabo ngesikhathi esifanayo njalo ekuseni ukuze bagcine amazinga aqhubekayo ohlelweni lwabo. Uma uhlangabezana nobunzima bokulala, udokotela wakho angase asikisele ukuthi uyithathe ekuseni. Abanye abantu bakhetha ukuyithatha nge-breakfast ukuze basize ukukhumbula umthamo wabo wansuku zonke futhi banciphise noma yikuphi ukungakhululeki kwesisu okungenzeka.

Ungayeki ukuthatha i-desvenlafaxine ngokuzumayo, ngisho noma uzizwa ungcono. Udokotela wakho uzodinga ukunciphisa kancane umthamo wakho ngokuhamba kwesikhathi ukuze avimbele izimpawu zokuhoxiswa. Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, kodwa uma sekuyisikhathi somthamo wakho olandelayo, weqa lowo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Desvenlafaxine?

Abantu abaningi badinga ukuthatha i-desvenlafaxine okungenani izinyanga eziyi-6 kuya kweziyi-12 ngemva kokuthi izimpawu zabo zithuthuke ukuze bavimbele ukubuya kokucindezeleka. Udokotela wakho uzosebenza nawe ukuze anqume ubude obufanele ngokuya ngesimo sakho ngasinye, okuhlanganisa ukuthi ukucindezeleka kwakho kwakunzima kangakanani nokuthi ngabe uke waba neziqephu ezedlule.

Kubantu abaningi, lo muthi uba yingxenye yohlelo lokwelashwa lwesikhathi eside. Abanye abantu bangase badinge ukuqhubeka bewuthatha iminyaka eminingi, ikakhulukazi uma behlangabezane neziqephu eziningi zokucindezeleka noma benezinye izici eziyingozi. Lokhu akuyona into engavamile futhi akusho ukuthi uthembele emuthini ngendlela engaphilile.

Isinqumo sokuthi kufanele kuqhubeke isikhathi esingakanani ukwelashwa kufanele senziwe njalo nodokotela wakho. Bazohlola njalo ukuthi usabela kanjani emuthini nokuthi usukulungele yini ukuqala ukuyeka. Ungayeki ukuthatha i-desvenlafaxine ngokwakho, ngoba lokhu kungaholela ezimpawini ezingakhululeki zokuyeka futhi kungase kubangele ukuthi ukucindezeleka kubuye.

Yiziphi Izimo Ezibangelwa I-Desvenlafaxine?

Njengayo yonke imithi, i-desvenlafaxine ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi imild kuya kokulingene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala okwelashwa.

Imiphumela emibi evame kakhulu ongase uyithole ihlanganisa isicanucanu, isiyezi, umlomo owomile, nokuqunjelwa. Le miphumela ivame ukuba yesikhashana futhi ilawuleka ngamasu alula afana nokuthatha umuthi nokudla noma ukuhlala unamanzi kahle usuku lonke.

Imiphumela Ejwayelekile Emibi

Nansi imiphumela emibi abantu abaningi abayitholayo lapho beqala i-desvenlafaxine, futhi iningi lalokhu livame ukuncipha ngokuhamba kwesikhathi:

• Isicanucanu nokuphazamiseka kwesisu
• Isiyezi noma ukuzwa ukukhanya ekhanda
• Umlomo owomile
• Ukuqunjelwa
• Ukuncipha kwesifiso sokudla
• Ukuhluleka ukulala noma amaphupho angajwayelekile
• Ukujuluka okwengeziwe
• Ukukhathala noma ukozela
• Ikhanda
• Imiphumela emibi yocansi, njengokuncipha kwentshisekelo noma ubunzima ekusebenzeni

Le miphumela emibi ngokuvamile imild futhi umzimba wakho uvame ukuyijwayela emasontweni ambalwa. Uma ziqhubeka noma ziba yinkinga, khuluma nodokotela wakho ngamasu okulawula zona.

Imiphumela Emibi Engathi Sína

Nakuba kungavamile, kunezinye izimo ezingathi sína ezidinga ukunakekelwa kwezokwelapha ngokushesha uma zenzeka:

• Ukuphendula okukhulu komzimba ngamachashaza, ukuvuvukala, noma ubunzima bokuphefumula
• Imicabango noma ukuziphatha kokuzibulala, ikakhulukazi kubantu abasha abangaphansi kweminyaka engu-25
• Ukuphuma kwegazi okungavamile noma ukulimala
• Isiyezi esikhulu noma ukuquleka
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Isicanucanu esikhulu, ukuhlanza, noma isifo sohudo
• Ukudideka noma izinkinga zenkumbulo
• Ukuqina kwemisipha noma ukuthuthumela
• Ikhanda elibuhlungu elikhulu noma izinguquko embonweni
• Izimpawu ze-serotonin syndrome: umkhuhlane, ukushaya kwenhliziyo okusheshayo, ukuqina kwemisipha, ukudideka

Uma uhlangabezana nanoma yimaphi alawa maphuzu amabi, xhumana nodokotela wakho ngokushesha noma funa ukwelashwa okuphuthumayo.

Imiphumela emibi engavamile kodwa ebalulekile

Kukhona imiphumela emibi engavamile eyenzeka ngamaphesenti amancane abantu abathatha i-desvenlafaxine:

• I-Angle-closure glaucoma (ubuhlungu obuzumayo emehlweni, izinguquko embonweni, ukubona ama-halos ezungeze izibani)
• I-Hyponatremia (amazinga aphansi e-sodium abangela ikhanda, ukudideka, ubuthakathaka)
• Ukuphuma kwegazi okungajwayelekile, ikakhulukazi uma futhi uthatha ama-blood thinners
• Izimpawu zokuhoxiswa uma kumiswa kungazelelwe
• Ukwenziwa kwe-mania noma i-hypomania kubantu abane-bipolar disorder
• Ukwanda kwengcindezi yegazi
• Izinkinga zesibindi (ezingavamile kodwa zidinga ukuqapha)

Udokotela wakho uzokuqapha ngale miphumela engavamile futhi angase ayale ukuhlolwa kwegazi ngezikhathi ezithile ukuze ahlolisise impilo yakho yonke ngenkathi uthatha lo muthi.

Ubani okungafanele athathe i-Desvenlafaxine?

I-Desvenlafaxine ayiphephile kuwo wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Akufanele uthathe lo muthi uma unokungezwani komzimba ne-desvenlafaxine, venlafaxine, noma yiziphi izithako zamaphilisi.

Akufanele futhi uthathe i-desvenlafaxine uma njengamanje uthatha noma usanda kuyeka ukuthatha ama-monoamine oxidase inhibitors (MAOIs), olunye uhlobo lwe-antidepressant. Kudingeka kube nebanga okungenani lezinsuku eziyi-14 phakathi kokuyeka i-MAOI nokuqala i-desvenlafaxine ukuze kugwenywe ukuxhumana okuyingozi.

Abantu abanezimo ezithile zezokwelapha badinga ukucatshangelwa okukhethekile ngaphambi kokuthatha lo muthi. Udokotela wakho uzohlola ukuthi i-desvenlafaxine iphephile yini uma unezinkinga zenhliziyo, umfutho wegazi ophezulu, isifo sesibindi noma sezinso, i-glaucoma, noma umlando wokuhlaselwa yizithuthwane. Abesifazane abakhulelwe noma abancelisayo kufanele baxoxe ngezinhlobo zazo zonke izingozi nezinzuzo ngokucophelela nomhlinzeki wabo wezempilo.

Amagama Omkhiqizo we-Desvenlafaxine

Igama elivamile lomkhiqizo we-desvenlafaxine yi-Pristiq, ekhiqizwa yi-Pfizer. Leli igama lomkhiqizo wokuqala lapho umuthi waqala ukuthengiswa futhi lisaziwa kakhulu ngabadokotela neziguli.

Izinhlobo ezivamile ze-desvenlafaxine nazo ziyatholakala futhi ziqukethe isithako esifanayo esisebenzayo njengohlobo lomkhiqizo. Lezi zinketho ezivamile zivame ukuba zishibhile ngenkathi zinikeza izinzuzo ezifanayo zokwelapha. Umuthi wakho wemithi angakusiza ukuthi uqonde ukuthi ngabe uthola igama lomkhiqizo noma uhlobo olujwayelekile.

Noma ngabe uthatha igama lomkhiqizo i-Pristiq noma uhlobo olujwayelekile, umuthi kufanele usebenze ngendlela efanayo. Abanye abantu bakhetha ukunamathela kumkhiqizi oyedwa ukuze bavumelane, kanti abanye bazizwa bekhululekile ukushintsha phakathi kwezinhlobo ezivamile ukonga imali.

Ezinye izindlela ze-Desvenlafaxine

Uma i-desvenlafaxine ingakulungele, kunezinhlobo eziningi ze-antidepressants ezingenye udokotela wakho angazicabangela. Eminye imithi ye-SNRI efana ne-venlafaxine (Effexor) noma i-duloxetine (Cymbalta) isebenza ngendlela efanayo kodwa ingahle ibe namaphrofayili ahlukene emiphumeleni noma amashejuli okulinganisa.

Imithi yokucindezeleka ye-SSRI efana ne-sertraline (Zoloft), i-escitalopram (Lexapro), noma i-fluoxetine (Prozac) enye inketho. Le mithi isebenza ngendlela ehlukile kancane ngokugxila ikakhulukazi ku-serotonin kunokuba kokubili i-serotonin ne-norepinephrine. Bangase bakwazi ukubekezelelwa kangcono ngabanye abantu.

Kubantu abangayiphenduli kahle i-SSRIs noma i-SNRIs, kunezinye izigaba zemithi yokucindezeleka okufanele zicatshangelwe. Lokhu kufaka phakathi imithi yokucindezeleka engajwayelekile efana ne-bupropion (Wellbutrin) noma i-mirtazapine (Remeron), ngalinye linenzuzo yalo eyingqayizivele kanye namaphrofayili emiphumela emibi. Udokotela wakho uzokusiza ukuthi uthole umuthi osebenza kahle kakhulu esimweni sakho esithile.

Ingabe i-Desvenlafaxine Ingcono Kune-Venlafaxine?

I-Desvenlafaxine ne-venlafaxine ziyimithi ehlobene eduze, kodwa zomehluko obalulekile. I-Desvenlafaxine empeleni iyifomu elisebenzayo le-venlafaxine, okusho ukuthi umzimba wakho uguqula i-venlafaxine ibe yi-desvenlafaxine uma uyithathile.

Inzuzo enkulu ye-desvenlafaxine ukuthi inikeza imiphumela evumelana kakhulu phakathi kwabantu abahlukene. Njengoba uthola isithako esisebenzayo ngokuqondile, kuncane ukwehluka endleleni umzimba wakho osebenza ngayo umuthi. Lokhu kungaholela emiphumeleni engabikezelwa kakhulu futhi okungenzeka ukuthi imiphumela emibi embalwa.

I-Desvenlafaxine nayo ivame ukuba nokuxhumana okuncane kwemithi uma kuqhathaniswa ne-venlafaxine, okwenza kube lula ukuhlanganisa neminye imithi. Kodwa-ke, yomibili imithi iyasebenza ekwelapheni ukucindezeleka, futhi udokotela wakho uzocabangela izidingo zakho ngazinye, umlando wezokwelapha, nezinye izinto lapho enquma ukuthi iyiphi engasebenza kangcono kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Desvenlafaxine

Ingabe i-Desvenlafaxine Iphephile Kubantu Abanezifo Zenhliziyo?

I-Desvenlafaxine ingasetshenziswa ngokuphepha kubantu abaningi abanezifo zenhliziyo, kodwa idinga ukuqashwa ngokucophelela. Umuthi ungakhuphula kancane umfutho wegazi nesivinini senhliziyo kwabanye abantu, ngakho udokotela wakho uzofuna ukuhlola impilo yakho yenhliziyo nemithambo yegazi ngaphambi kokuqala ukwelashwa.

Uma unesifo senhliziyo, udokotela wakho cishe uzoqapha umfutho wegazi lakho nesivinini senhliziyo ngokusondela kakhulu emasontweni ambalwa okuqala okwelashwa. Bangase futhi bancomise ukuqala ngomthamo ophansi bese bewukhulisa kancane kancane ukunciphisa noma yimiphi imiphumela yenhliziyo nemithambo yegazi.

Kufanele Ngenzeni Uma Ngithatha I-Desvenlafaxine Ngengozi Ngokweqile?

Uma ngengozi uthatha i-desvenlafaxine eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela izimpawu ezinzima njengokushaya kwenhliziyo okusheshayo, umfutho wegazi ophezulu, isiyezi, isicanucanu, noma ukudideka.

Ungazami ukuzenza uhlanze noma ulinde ukubona ukuthi izimpawu ziyavela yini. Noma ngabe uzizwa kahle, kubalulekile ukuthola iseluleko sezokwelapha ngoba eminye imiphumela yokweqisa ingase ingaveli ngokushesha. Gcina ibhodlela lomuthi unawo lapho ufuna usizo lwezokwelapha ukuze abahlinzeki bezempilo bazi kahle ukuthi uthathe ini nokuthi ungakanani.

Kufanele Ngenzeni Uma Ngeqa Umthamo We-Desvenlafaxine?

Uma weqa umthamo we-desvenlafaxine, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo oweqiwe bese uqhubeka neshejuli yakho yokulinganisa ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo oweqiwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha i-alamu yansuku zonke noma usebenzise umhleli wamaphilisi ukukusiza ukhumbule. Ukulinganisa kwansuku zonke okuqhubekayo kubalulekile ekugcineni amazinga aqhubekayo omuthi ohlelweni lwakho.

Ngingayeka Nini Ukuthatha I-Desvenlafaxine?

Kufanele uyeke ukuthatha i-desvenlafaxine ngaphansi kokuqondisa kukadokotela wakho kuphela, ngisho noma uzizwa ungcono kakhulu. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa njengokuphatheka kabi ikhanda, isicanucanu, ikhanda elibuhlungu, kanye nezinguquko zemizwa ezingaba zimbi kakhulu.

Udokotela wakho uzokwenza isimiso sokunciphisa esinciphisa kancane kancane umthamo wakho emasontweni amaningana noma izinyanga. Lokhu kuvumela ubuchopho bakho ukuthi bujwayele kancane amazinga aphansi omuthi. Inqubo yokunciphisa yenziwa ngamunye ngamunye ngokusekelwe ekutheni usuthatha isikhathi esingakanani umuthi kanye nomthamo wakho wamanje.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Desvenlafaxine?

Kungcono ukugwema utshwala noma ukululinganisa kakhulu ngenkathi uthatha i-desvenlafaxine. Utshwala bungandisa imiphumela yokuthulisa yomuthi futhi kungase kwenze ngcono izimpawu zokucindezeleka noma ukukhathazeka. Kungase futhi kwandise ingozi yakho yemiphumela emibi eyingozi njengokuphatheka kabi noma ukwahlulela okungahambisani kahle.

Uma ukhetha ukuphuza ngezikhathi ezithile, yenza kanjalo ngokulinganisela okukhulu futhi unake indlela ozizwa ngayo. Ungalokothi uphuze utshwala uma uqala ukuthatha umuthi noma ngemva kokwanda komthamo, njengoba ngeke wazi ukuthi umzimba wakho uzosabela kanjani. Njalo xoxa ngokusebenzisa kwakho utshwala ngobuqotho nodokotela wakho ukuze bakwazi ukukunikeza isiqondiso esiqondene nawe.