Yini i-Dexmedetomidine (Indlela ye-Oromucosal): Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Dexmedetomidine oromucosal iyisidakamizwa esikhethekile esithathwa ngezicubu emlonyeni wakho, ngokuvamile sinikezwa njengefilimu noma ijeli elincibilikayo phakathi kwamazinyo akho nezihlathi. Le ndlela ethambile yokuthulisa ingqondo isiza ukunciphisa ukukhathazeka futhi inikeze ukuphumula ngaphandle kwesidingo sokujova noma imigqa ye-IV.

Ungase uhlangane nalolu hlobo lomuthi uma wena noma othandekayo wakho nidinga ukuthuliswa ngenxa yezinqubo zezokwelapha, ikakhulukazi ezindaweni zezingane lapho izindlela zendabuko zingase zibangele ukucindezeleka okwengeziwe. Indlela ye-oromucosal isho ukuthi umuthi usebenza ngokumuncwa ngokuqondile ngezicubu ezithambile emlonyeni wakho, okwenza kube usizo ikakhulukazi ezimweni lapho ezinye izinhlobo zokuthulisa zingasebenzi noma zingathandeki.

Yini i-Dexmedetomidine?

I-Dexmedetomidine iyisidakamizwa esikhetheke kakhulu esilingisa izimpawu zomzimba wakho zokuzola ebuchosheni nasohlelweni lwezinzwa. Ingaphansi kwesigaba semithi ebizwa ngokuthi ama-alpha-2 adrenergic agonists, okusho ukuthi isebenza ngokuvula ama-receptors athile asiza umzimba wakho ukuthi uphumule futhi uzizwe ukozela.

Okuhlukanisa lo muthi ngamandla awo okunikeza ukuthuliswa ngenkathi kukuvumela ukuthi uhlale uphendula okuthile endaweni okuyo. Ngokungafani neminye imithi yokuthulisa engakwenza ungaphatheki nhlobo, i-dexmedetomidine idala isimo esingokwemvelo, esifana nokulala lapho usengavuswa ngobumnene uma kudingeka.

Ifomula ye-oromucosal iyinto entsha ngoba idlula ngokuphelele uhlelo lokugaya ukudla. Esikhundleni sokugwinya iphilisi elidinga ukuthi liqhekekwe esiswini sakho, umuthi umuncwa ngokuqondile ngokusetshenziswa kwegazi elicebile ezicutshini zomlomo wakho, okuholela emiphumeleni esheshayo neqikelelekayo.

Isetshenziselwani i-Dexmedetomidine?

I-Dexmedetomidine oromucosal isetshenziswa kakhulu ukusiza ukunciphisa ukukhathazeka nokuhlinzeka ngemithi yokulalisa ngaphambi kwezinqubo zezokwelapha, ikakhulukazi ezinganeni nakweziguli ezingase zibe nobunzima ngezindlela zokulalisa ezivamile. Kubaluleke kakhulu emithini yezingane lapho ukudala indawo ezolile, engenakucindezeleka kubalulekile kokubili enganeni nethimba lezokwelapha.

Umuthi ubonakala ulusizo ikakhulukazi ezimweni eziningana ezithile. Ungase uhlangane nakho uma ulungiselela izinqubo zamazinyo, ukuhlinzwa okuncane, noma izivivinyo zokuxilonga ezinjenge-MRIs lapho ukuhlala uzinzile futhi uphumule kubalulekile. Isetshenziswa futhi ezindaweni zokunakekelwa okukhulu ukusiza iziguli ezisebenzisa imishini yokuphefumula ukuthi zihlale zikhululekile ngaphandle kokulaliswa kakhulu.

Abahlinzeki bezempilo bavame ukukhetha le ndlela lapho iziguli ziba nobunzima bokugwinya amaphilisi, lapho ukufinyelela kwe-IV kuyinselele, noma lapho kuqondiswa ukuqala okuncane kokulaliswa. Indlela ye-oromucosal ilusizo ikakhulukazi ezinganeni ezingase zesatshiswe yizinaliti noma ezigulini ezindala ezingase zibe nemithambo ebuthaka.

Kwezinye izimo, i-dexmedetomidine oromucosal ingasetshenziswa njengengxenye yohlelo olubanzi lokulalisa, isebenza kanye neminye imithi ukudala ulwazi olukhululeke kakhulu ngangokunokwenzeka. Ithimba lakho lezokwelapha lizinquma ukuthi le ndlela ilungile yini esimweni sakho esithile ngokusekelwe emlandweni wakho wezempilo kanye nenqubo oyenzayo.

Isebenza Kanjani I-Dexmedetomidine?

I-Dexmedetomidine isebenza ngokugxila kuma-receptors athile ebuchosheni bakho abizwa ngokuthi ama-alpha-2 adrenergic receptors, afana nezinkinobho ezincane ezilawula ukusabela komzimba wakho ekucindezelekeni namaphethini okulala. Lapho umuthi ubopha kula ma-receptors, uthumela amasignali asiza uhlelo lwakho lwezinzwa ukuthi lushintshele esimweni esizolile, esiphumuzayo.

Cabanga ngakho njengokuthi wehlise ivolumu ohlelweni lwakho lomzimba lwe-alamu yemvelo. Ubuchopho bakho ngokwemvelo buveza amakhemikhali afana ne-norepinephrine akugcina uqaphile futhi ukulungele ukusabela endaweni okuzungezile. I-Dexmedetomidine isiza ukunciphisa ukukhishwa kwala makhemikhali akhuthazayo, okuvumela ingqondo nomzimba wakho ukuthi zizithole zizinzile, zibe sesimweni sokulala.

Lo muthi uthathwa njengomuthi onamandla ngokulinganisela emiphumeleni yawo yokuthulisa, unikeza ukuphumula okukhulu ngaphandle kwemiphumela enamandla ye-anesthesia ejwayelekile. Idala lokho odokotela abakubiza ngokuthi “ukuthuliswa okwaziwayo,” lapho usalokhu uqaphela kodwa uphumule kakhulu futhi uzizwa ukhululekile. Lokhu kwenza kuphephe kunemithi yokuthulisa enamandla ngoba usengakwazi ukuphefumula ngokwakho futhi uphendule emiyalweni ebalulekile.

Indlela ye-oromucosal ivumela umuthi ukuthi umuncwe ngokuqondile egazini lakho ngenethiwekhi ecebile yemithambo yegazi emlonyeni wakho. Lokhu kudlula uhlelo lwakho lokugaya ukudla, okusho ukuthi imiphumela iqala ngokushesha futhi ngendlela elindelekile kunokuthi uginye iphilisi. Abantu abaningi baqala ukuzwa imiphumela yokuthulisa phakathi kwemizuzu engama-30 kuya kwengama-60 ngemva kokunikezwa.

Kufanele Ngiyithathe Kanjani I-Dexmedetomidine?

I-Dexmedetomidine oromucosal inikezwa kuphela ochwepheshe bezempilo abaqeqeshiwe ezindaweni zezokwelapha, ngakho ngeke uthathe lo muthi ekhaya. Ukulungiswa nokuphathwa kudinga ukuqeqeshwa okuthile ukuze kuqinisekiswe ukuphepha nokusebenza kahle.

Lapho uthola lo muthi, umhlinzeki wakho wezempilo uzobeka ifilimu elincane noma afake i-gel phakathi kwamazinyo akho nesihlathi, ngokuvamile ngaphakathi komlomo wakho ongezansi noma emagunjini akho. Uzoqeqeshwa ukuthi uvale umlomo wakho futhi ugweme ukugwinya, ukukhuluma, noma ukuphuza isikhathi esithile ukuze uvumele ukumuncwa okufanele ngezicubu zomlomo.

Ngaphambi kokuthola umuthi, ithimba lakho lezempilo cishe lizokucela ukuthi ugweme ukudla noma ukuphuza isikhathi esithile, ngokuvamile amahora angu-2-4 ngaphambi kwalokho. Lokhu kusiza ukuqinisekisa ukuthi umuthi umuncwa kahle futhi kunciphisa ingozi yanoma yiziphi izinkinga. Uma ugqoka amazinyo okwenziwa noma unamanxeba emlonyeni noma ukulimala, qiniseka ukuthi wazisa umhlinzeki wakho wezempilo ngoba lokhu kungase kuthinte indlela umuthi onikezwa ngayo.

Ngesikhathi senqubo yokuphatha, ungase ucelwe ukuthi uhlale endaweni enethezekile futhi uzame ukuphumula. Abanye abantu bazwa ukunambitheka okubabayo kancane, okuvamile. Ithimba lakho lezempilo lizokuqapha eduze kuyo yonke inqubo, lihlole ukuphefumula kwakho, izinga lokushaya kwenhliziyo, kanye nezinga lokuqwashisa ukuze liqinisekise ukuthi uphendula kahle emuthini.

Kufanele Ngithathe Isikhathi Esingakanani I-Dexmedetomidine?

I-Dexmedetomidine oromucosal ngokuvamile iyidosi eyodwa enikezwa ngokuqondile ngenqubo eyodwa noma ukungenelela kwezokwelapha. Ngokungafani nemithi ongase uyithathe nsuku zonke ekhaya, lokhu kuphathwa kuphela uma kudingeka ukuthulisa ezigodini zezempilo.

Imiphumela yedosi eyodwa ivame ukuhlala phakathi kwamahora angu-2 kuya kwangu-6, kuye ngokuthi impendulo yakho, idosi enikeziwe, kanye nempilo yakho yonke. Abantu abaningi bathola ukuthi imiphumela enamandla yokuthulisa iyenzeka phakathi nehora lokuqala nelama-2 ngemuva kokuphathwa, ngokususa kancane kancane emahoreni alandelayo.

Ithimba lakho lezempilo lizoqhubeka likuqapha kuze kube yilapho imiphumela isiphelile ngokwanele futhi uqwashile ngokwanele ukuthi ushiye ngokuphepha isikhungo sezokwelapha. Lokhu kungasho ukuhlala ukuze ubukwe amahora amaningana ngemuva kwenqubo yakho, ikakhulu uma uthole idosi ephezulu noma uma uzwela kakhulu emuthini.

Kwezinye izimo zokunakekelwa okukhulu, i-dexmedetomidine ingase isetshenziswe ngokuphindaphindiwe ezinsukwini eziningana, kodwa lokhu kungenzeka kuphela ngaphansi kokugadwa okuseduze kwezokwelapha esibhedlela. Isinqumo mayelana nobude besikhathi sihlala sincike ezidingweni zakho zezokwelapha kanye nokuthi usabela kahle kangakanani ekwelashweni.

Yiziphi Imiphumela Eceleni ye-Dexmedetomidine?

Njengayo yonke imithi, i-dexmedetomidine ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle uma isetshenziswa ngendlela efanele. Imiphumela emibi evame kakhulu ngokuvamile imnene futhi ihlobene nezakhiwo zokuthulisa zomuthi.

Imiphumela emibi ongase uyithole ingahlukaniswa ibe yilezo ezivamile, ezilawulekayo kanye nalezo ezingavamile kodwa ezingathi sína ezidinga ukunakekelwa kwezokwelapha. Ukuqonda lokhu kukusiza ukuthi wazi ukuthi yini ongayilindela nokuthi kufanele ukhathazeke nini.

Imiphumela emibi evamile ongase uyibone ihlanganisa:

• Ukozela nokuzizwa ulele amahora amaningana ngemva kokuphathwa
• Umlomo owomile, ongahlala amahora ambalwa
• Isicanucanu esincane noma isisu esibuhlungu
• Isiyezi noma ukuzizwa unovalo lapho usukuma
• Ushintsho lwesikhashana emfutheni wegazi, ngokuvamile ukwehla
• Ukushaya kwenhliziyo okuhamba kancane kunokujwayelekile
• Ikhanda elincane njengoba umuthi uphela

Le miphumela evamile ngokuvamile yesikhashana futhi iyanyamalala njengoba umzimba wakho usebenza ngomuthi. Ithimba lakho lezempilo lilindele lokhu futhi lizokuqapha ngokufanele.

Imiphumela emibi engavamile kodwa engathi sína edinga ukunakekelwa kwezokwelapha ngokushesha ihlanganisa:

• Ubunzima obukhulu bokuphefumula noma ukuphefumula kancane kakhulu
• Ukwehla okukhulu komfutho wegazi okubangela ukuquleka
• Ukushaya kwenhliziyo okuhamba kancane kakhulu noma okungajwayelekile
• Ukuphendula komzimba ngemithi okune-rash, ukuvuvukala, noma ubunzima bokuphefumula
• Ukuthuliswa isikhathi eside okuhlala isikhathi eside kakhulu kunokulindelekile
• Ukudideka okukhulu noma ukucasuka njengoba umuthi uphela

Iqembu lakho lezokwelapha liqeqeshwe ukubona nokuphatha le miphumela engathi sína, yingakho lo muthi unikezwa kuphela ezindaweni zezokwelapha eziqondiswayo.

Izinkinga ezingavamile kodwa ezingathi sína zingabandakanya:

• Imiphumela emibi yenhliziyo nemithambo yegazi edinga ukungenelela ngokushesha
• Ukuthuliswa okungalindelekile okude okudinga ukuqapha okwengeziwe
• Ukungezwani komzimba okungavamile okungadinga ukwelashwa okuphuthumayo
• Ukusebenzisana neminye imithi okubangela imiphumela engalindelekile

Ingozi yezinkinga ezingathi sína iphansi kakhulu uma umuthi usetshenziswa ngendlela efanele, kodwa ithimba lakho lezempilo lizobe lilungele ukubhekana nanoma yisiphi isimo esingase sivele.

Obani okungafanele bathathe i-Dexmedetomidine?

Abantu abathile akufanele bathole i-dexmedetomidine oromucosal ngenxa yengozi eyengeziwe yezinkinga. Umhlinzeki wakho wezempilo uzobuyekeza ngokucophelela umlando wakho wezokwelapha ukuze anqume ukuthi lo muthi uphephile yini kuwe.

Abantu abanezimo ezithile zenhliziyo kungenzeka bangabi ngabantu abafanelekayo kulo muthi. Uma unezinkinga ezinzima zokushaya kwenhliziyo, umfutho wegazi ophansi kakhulu, noma izinhlobo ezithile zokuvinjwa kwenhliziyo, i-dexmedetomidine ingase iqhubekisele phambili lezi zimo. Udokotela wakho uzodinga ukwazi nganoma yiziphi izinkinga zenhliziyo owake waba nazo, okuhlanganisa izigameko zokuquleka noma ukushaya kwenhliziyo okungajwayelekile.

Kufanele wazise umhlinzeki wakho wezempilo uma unezinye zalezi zimo:

• Izifo ezinzima zokushaya kwenhliziyo noma ukuvinjwa kwenhliziyo
• Umfutho wegazi ophansi kakhulu noma umlando wokuquleka
• Izinkinga ezinzima zesibindi ezithinta ukucutshungulwa kwemithi
• Ukungezwani komzimba okwaziwayo ne-dexmedetomidine noma imithi efanayo
• Izinkinga ezinkulu zokuphefumula noma i-sleep apnea
• Ukwelashwa kwamuva ekhanda noma ukwanda kwengcindezi ebuchosheni
• Ukukhulelwa noma ukuncelisa

Ubudala bungaba yisici ekunqumeni ukuphepha. Nakuba le mithi ivame ukusetshenziswa ezinganeni, izinsana ezincane kakhulu neziguli ezindala kakhulu zingase zidinge ukucatshangelwa okukhethekile noma ukulungiswa kwemithamo. Ithimba lakho lezempilo lizofaka ubudala bakho kanye nesimo sakho sempilo esiphelele.

Imithi ethile ingase ihlangane ngendlela eyingozi ne-dexmedetomidine, okuhlanganisa:

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• Imithi yokwehlisa umfutho wegazi, ikakhulukazi izinhlobo ezithile
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• Imithi yokulawula isigqi senhliziyo
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• Ezinye izidambisi noma imithi yokulala
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• Ezinye izidambisi zokucindezeleka
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• Imithi ethinta ukusebenza kwesibindi
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Njalo nikeza ithimba lakho lezempilo uhlu oluphelele lwazo zonke izidakamizwa, izithasiselo, nemikhiqizo yamakhambi oyithathayo, ngisho noma ibonakala ingahlobene nokwelashwa kwakho kwamanje.

Amagama Omkhiqizo we-Dexmedetomidine

I-Dexmedetomidine oromucosal itholakala ngaphansi kwegama lomkhiqizo elithi Igalmi, elenzelwe ngqo ukuphathwa ngezicubu zomlomo. Lokhu kwehluka ohlotsheni lwe-IV lwe-dexmedetomidine oluhamba ngamagama omkhiqizo afana ne-Precedex.

I-Igalmi iza njengefilimu elincanyana elincibilikayo phakathi kwamazinyo akho nesihlathi, okwenza kube usizo ikakhulukazi ezimweni lapho ukufinyelela kwe-IV kunzima noma lapho indlela engahlaseli yokudambisa ikhethwa. Ifomula ethile yakhelwe ukuhlinzeka ngokumuncwa okuthembekile ngezicubu zomlomo.

Umhlinzeki wakho wezempilo angase futhi abhekisele kule mithi ngegama layo elivamile, i-dexmedetomidine, elilandelwa yi-

Imithi eminingi ehlukile inganikeza imiphumela efanayo yokuthulisa, nakuba ngayinye inezinzuzo zayo kanye nezinto okufanele zicatshangelwe. Umhlinzeki wakho wezempilo uzokhetha inketho engcono kakhulu ngokusekelwe esimweni sakho esithile, umlando wakho wezokwelapha, kanye nohlobo lwenqubo oyenzayo.

Imithi yokuthulisa ngomlomo efana ne-midazolam (Versed) noma i-lorazepam (Ativan) ivame ukusetshenziswa njengezinye izindlela ozigwinya ngesimo samanzi noma ithebhulethi. Le mithi isebenza ngendlela ehlukile kune-dexmedetomidine kodwa inganikeza ukukhululeka okusebenzayo ekukhathazekeni kanye nokuthulisa. Nokho, kungase kuthathe isikhathi eside ukusebenza futhi ngezinye izikhathi kungabangela imiphumela engabikezeleki.

Ezinye izindlela ezingase zicatshangelwe ngumhlinzeki wakho wezempilo zihlanganisa:

• I-Nitrous oxide (igesi yokuhleka) yokuthulisa okulula ngesikhathi sezinqubo
• Ukuthulisa nge-IV ngemithi efana ne-propofol noma i-midazolam
• Imithi yokuthulisa ngomlomo ethathwa ngaphambi kokufika esikhungweni sezokwelapha
• Imithi engaphakathi ekhaleni yezingane ezingakwazi ukugwinya amaphilisi
• Ama-anesthetics aphezulu ahlanganiswe nemithi yokuthulisa ngomlomo elula

Ngayinye enye indlela inezikhathi zokuqala ezihlukene, ubude, kanye namaphrofayili emiphumela emibi. Indlela ye-oromucosal ye-dexmedetomidine inikeza izinzuzo ezihlukile mayelana nokugwema izinaliti ngenkathi isahlinzeka ngemiphumela ethembekile, ebonakalayo engagadiwa eduze.

Ithimba lakho lezempilo lizoxoxa ngezinto ezinhle nezingezinhle zezinketho ezihlukene nawe, licabangela izinga lakho lokunethezeka, umlando wezokwelapha, kanye nezidingo ezithile zenqubo yakho ukuze kunqunywe ukukhetha okufanele kakhulu.

Ingabe i-Dexmedetomidine Ingcono Kune-Midazolam?

Kokubili i-dexmedetomidine ne-midazolam ziyizidakamizwa ezisebenzayo, kodwa zisebenza ngezindlela ezihlukene futhi zinezinzuzo ezihlukile kuye ngesimo sakho esithile. Akukho noyedwa ongcono kunomunye - ukukhetha kuncike ezidingweni zakho ngazinye kanye nezimo zezokwelapha.

I-Dexmedetomidine inikeza ezinye izinzuzo eziyingqayizivele ezenza ukuthi ithandeke ezimweni ezithile. Ivame ukubangela ukucindezeleka okuncane kokuphefumula, okusho ukuthi mancane amathuba okuthi yehlise ukuphefumula kwakho kakhulu. Lokhu kuyenza iphephe kubantu abanezinkinga zokuphefumula noma i-sleep apnea. Ngaphezu kwalokho, iziguli zivame ukuzwa ukuthula okungokwemvelo, okufana nokulala okubenza bakwazi ukuvuka kalula uma kudingeka.

Ngakolunye uhlangothi, i-Midazolam isebenza ngokushesha ezimweni eziningi futhi inikeza ukukhululeka okusebenzayo kakhulu kokukhathazeka. Isetshenziswe ngokuphepha amashumi eminyaka futhi itholakala ngezindlela eziningi ezihlanganisa imizila yomlomo, i-IV, kanye ne-intranasal. Abahlinzeki bezempilo abaningi bajwayelene kakhulu nemiphumela yayo nokuthi bangayilawula kanjani noma yimiphi imiphumela engase yenzeke.

I-Dexmedetomidine ingase ithandwe uma:

• Unezinkinga zokuphefumula noma i-sleep apnea
• Kudingeka ukuthula okungokwemvelo, okulula ukuguqulwa
• Udinga ukuhlala uphendula ngesikhathi senqubo
• Unomlando wokuphendula okungajwayelekile kwezinye izidambisi
• Kufuneka ukuthula okuhlala isikhathi eside

I-Midazolam ingase ikhethwe uma:

• Kudingeka ukuqala okusheshayo kokuthula
• Inqubo imfushane
• Kufuneka imiphumela eqinile ye-amnesia
• Izindleko zibalulekile
• Ithimba lezempilo linolwazi oluningi ngalo muthi

Umhlinzeki wakho wezempilo uzocabangela izici ezinjengomlando wakho wezokwelapha, uhlobo lwenqubo, ubude obulindelekile, kanye nokuhlangenwe nakho kwakho kwangaphambilini ngokuthula ukuze unqume ukuthi yimuphi umuthi ofaneleka kakhulu esimweni sakho.

Imibuzo Evame Ukubuzwa Mayelana ne-Dexmedetomidine

Ingabe i-Dexmedetomidine iphephile ezigulini zenhliziyo?

I-Dexmedetomidine ingasetshenziswa ngokuphepha ezigulini eziningi zenhliziyo, kodwa idinga ukuhlolwa nokuqapha okucophelelayo. Umuthi ungathinta izinga lokushaya kwenhliziyo nomfutho wegazi, ngakho udokotela wakho wenhliziyo kanye nethimba lezokwelapha eliphatha ukuthuliswa kwengqondo kuzodingeka basebenzisane ukuze banqume ukuthi kufanele yini isimo sakho senhliziyo esithile.

Uma unesifo senhliziyo esizinzile ngaphandle kwezinkinga ezinzima zesigqi noma umfutho wegazi ophansi kakhulu, i-dexmedetomidine ingase ibe ngcono kuneminye imithi yokuthulisa ngoba mancane amathuba okuthi idale ukwehla okukhulu komfutho wegazi. Kodwa-ke, abantu abanezinhlobo ezithile zokuvinjwa kwenhliziyo, amazinga okushaya kwenhliziyo aphansi kakhulu, noma izimo zenhliziyo ezingazinzile bangase badinge izindlela ezingezinye zokuthulisa.

Ithimba lakho lezempilo lizobuyekeza izivivinyo zakho zenhliziyo zakamuva, imithi yamanje, kanye nokuzinza kwenhliziyo konke ngaphambi kokwenza lesi sinqumo. Bangase futhi bahlele ukuqapha okwengeziwe ngesikhathi nangemva kokuthuliswa kwengqondo ukuze baqinisekise ukuthi inhliziyo yakho isabela kahle emuthini.

Kufanele Ngenzeni Uma Ngisebenzisa Ngengozi I-Dexmedetomidine Eningi Kakhulu?

Njengoba i-dexmedetomidine oromucosal iphathwa kuphela ochwepheshe bezempilo ezindaweni zezokwelapha, ukweqisa ngengozi yeziguli akunakwenzeka. Umuthi ulinganiswa ngokucophelela futhi unikezwa ngaphansi kokuqondisa okuqondile, okwenza ukweqisa okuziphatha ngokwakho kungabi nokwenzeka.

Uma umuthi omningi unikezwa ngengozi, ithimba lakho lezempilo lizobona ngokushesha izimpawu, ezingase zihlanganise ukuthuliswa kwengqondo okukhulu, ukuphefumula okuhamba kancane kakhulu, noma ukwehla okukhulu komfutho wegazi nezinga lokushaya kwenhliziyo. Izikhungo zezokwelapha lapho kusetshenziswa khona lo muthi zihlonyiswe ngemithi esheshayo nemishini yokuguqula le miphumela uma kudingeka.

Ithimba lezokwelapha lingahlinzeka ngosizo lokunakekela, okungabandakanya usizo lokuphefumula, uketshezi lwe-IV ukusekela umfutho wegazi, kanye nemithi yokulwa nokulaliswa ngokweqile. Izindawo zokululama zilungiselelwe lezi zimo ezingavamile futhi zinezindlela zokwenza zokuphepha kwesiguli.

Lesi ngesinye sezizathu ezibalulekile zokuthi kungani i-dexmedetomidine oromucosal isetshenziswa kuphela ezindaweni zezokwelapha eziqashwe – ukutholakala ngokushesha kochwepheshe abaqeqeshiwe kanye nemishini ephuthumayo kwenza imithi iphephe kakhulu kunokuba ibe njalo uma isetshenziswa ekhaya.

Ngingenzani uma ngiphuthelwa umthamo we-Dexmedetomidine?

Umqondo wokuthi

Awukwazi ukuzinqumela ukuyeka i-dexmedetomidine ngokwakho ngoba inikezwa futhi iqashwe ngokuphelele ochwepheshe bezempilo. Umuthi uyancipha ngokwemvelo emahoreni amaningana, futhi ithimba lakho lezokwelapha lizokuqapha kuze kube yilapho benelisekile ukuthi imiphumela inciphe ngokwanele ukuze ukwazi ukuhamba ngokuphepha usuke esikhungweni sezokwelapha.

Ezimweni eziningi, uzoqashwa amahora angu-2-6 ngemuva kokuthola umuthi, kuye ngomthamo kanye nokuphendula kwakho ngakunye. Ithimba lakho lezempilo lizohlola ukuqapha kwakho, ukuphefumula, umfutho wegazi, kanye nesilinganiso senhliziyo njalo ukuze linqume ukuthi umuthi ususulwe nini ngokwanele.

Ngokuvamile uzobe usulungele ukuhamba uma ukwazi ukuhamba ngokuqinile, ucabanga ngokucacile, futhi izimpawu zakho ezibalulekile zibuyele ebangeni elijwayelekile. Kodwa-ke, usazodinga umuntu ozokuqhuba ekhaya futhi kufanele ugweme ukwenza izinqumo ezibalulekile noma ukusebenzisa imishini ngosuku olusele.

Ezindaweni zokunakekelwa okukhulu lapho umuthi ungase usetshenziswe izinsuku eziningana, ithimba lezokwelapha lenza zonke izinqumo mayelana nokuthi lingayeka nini ukuyisebenzisa ngokusekelwe esimweni sakho sezokwelapha kanye nentuthuko yokululama. Bazokwehlisa kancane kancane inani noma bayeke ngokuphelele lapho ukuthulisa kungasadingeki ekunakekelweni kwakho.

Ngingakwazi yini ukuqhuba ngemuva kokuthola i-Dexmedetomidine?

Cha, akufanele uqhube okungenani amahora angu-24 ngemuva kokuthola i-dexmedetomidine oromucosal, ngisho noma uzizwa ujwayelekile ngokuphelele. Umuthi ungenza imiphumela eqhubekayo esikhathini sakho sokuphendula, ukwahlulela, kanye nokuxhumana ongase ungakuqapheli kodwa okungase kuthinte ukuphepha kwakho ekushayeleni.

Ngaphambi kwenqubo yakho, lungiselela umuntu omdala onomthwalo wemfanelo ukuthi akuqhubele ekhaya futhi ahlale nawe amahora amaningana. Lo muntu kufanele abe ngumuntu ongakusiza uma uhlangabezana nanoma yimiphumela elibazisekile evela emuthini futhi angasiza nganoma yizipho ezidingekayo ongase ube nazo ngesikhathi sokululama.

Noma ngemva kokuzwa uqaphile futhi ubuyele esimweni esijwayelekile, imiphumela emincane ekhona ezingqondweni zakho kanye namakhono okwenza izinqumo ingaqhubeka isikhathi eside kunokuthulisa okubonakalayo. Abantu abaningi bayayithatha kancane indlela le miphumela ehlala ngayo isikhathi eside, yingakho umthetho wamahora angama-24 ubalulekile ekuphepheni kwawo wonke umuntu.

Izinto zokuhamba zomphakathi, izinsizakalo zokwabelana ngemoto, noma izinsizakalo zamatekisi nazo azinconywa ngokushesha ngemva kokuthuliswa ngoba udinga umuntu ongakusiza uma uqala ukuba nesiyezi noma udideke ngesikhathi sohambo oluya ekhaya. Hlela kusengaphambili ukuqinisekisa ukuthi unokuthutha okufanele nokusekela isikhathi sakho sokululama.