Yini i-Enalapril ne-Hydrochlorothiazide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Enalapril ne-hydrochlorothiazide kuyinhlanganisela yemithi esiza ukulawula umfutho wegazi ophezulu ngokusebenzisa izindlela ezimbili ezihlukene ngesikhathi esisodwa. Le mithi esebenza kabili ihlanganisa i-ACE inhibitor (enalapril) ne-diuretic noma "ipilisi lamanzi" (hydrochlorothiazide) ukusiza inhliziyo yakho ukuba iphamphe kalula futhi inciphise ukwakheka koketshezi emzimbeni wakho.

Abantu abaningi bathola ukuthi le nhlanganisela isebenza ngempumelelo kakhulu kunokuthatha imithi eyodwa. Udokotela wakho angase akubhalele lokhu uma imithi eyodwa ingazange ilethe umfutho wakho wegazi ebangeni elinempilo, noma uma udinga izinzuzo zazo zombili izinhlobo zemithi zisebenza ndawonye.

Yini i-Enalapril ne-Hydrochlorothiazide?

Le mithi ihlanganisa imithi emibili esungulwe kahle yomfutho wegazi ibe iphilisi elilodwa elilula. I-Enalapril ingeyeqembu elibizwa ngokuthi ama-ACE inhibitors, asiza imithambo yegazi ukuba iphumule futhi yande. I-Hydrochlorothiazide iyi-thiazide diuretic esiza izinso zakho ukususa usawoti namanzi engeziwe emzimbeni wakho.

Uma le mithi emibili isebenza ndawonye, idala iqembu elinamandla ngokumelene nomfutho wegazi ophezulu. I-Enalapril isiza imithambo yakho yegazi ukuba ihlale iphumule, kuyilapho i-hydrochlorothiazide inciphisa inani loketshezi inhliziyo yakho okudingeka iliphamphe. Le ndlela yokuhlanganisa ivame ukusebenza kangcono kunomuthi owodwa.

Ngokuvamile uzothola le mithi itholakala ngezinhlanganisela zamandla ahlukene, okuvumela udokotela wakho ukuba alungise umthamo ngokusekelwe ezidingweni zakho ezithile. Izinhlanganisela ezivamile zihlanganisa amaphilisi angu-5mg/12.5mg, 10mg/25mg, kanye nama-20mg/25mg.

Isetshenziselwani i-Enalapril ne-Hydrochlorothiazide?

Le nhlanganisela yemithi isetshenziswa ikakhulukazi ukwelapha umfutho wegazi ophezulu, owaziwa nangokuthi i-hypertension. Umfutho wegazi ophezulu uthinta izigidi zabantu futhi ngokuvamile akubangeli izimpawu ezisobala, yingakho ngezinye izikhathi ubizwa ngokuthi "umbulali othule."

Udktela wakho angase akunike lo muthi uma izinombolo zakho zomfutho wegazi zihlala ngaphezu kuka-140/90 mmHg ngaphandle kokuthi ushintshe indlela yakho yokuphila. Umgomo uwukwehlisa izinombolo zakho zibe ezingeni elinempilo, ngokuvamile elingaphansi kuka-130/80 mmHg kubantu abaningi.

Ngaphandle kokwelapha umfutho wegazi ophezulu okhona, lo muthi futhi usiza ekuvikeleni izinkinga ezingathi sína ezingavela ngokuhamba kwesikhathi. Lokhu kufaka phakathi ukuhlaselwa yinhliziyo, ukushaywa unhlangothi, izinkinga zezinso, nokuhluleka kwenhliziyo. Ngokugcina umfutho wegazi wakho ulawulwa, uvikela inhliziyo yakho, ubuchopho, izinso, nemithambo yegazi ekulimaleni kwesikhathi eside.

Odokotela abathile bangase futhi banikeze le nhlanganisela kubantu abanenhliziyo ehlulekayo, nakuba lokhu kungavamile. Umuthi ungasiza ekunciphiseni umsebenzi enhliziyweni yakho futhi uthuthukise ukuthi iphampa kanjani igazi emzimbeni wakho wonke.

Isebenza Kanjani i-Enalapril ne-Hydrochlorothiazide?

Lo muthi ohlanganisiwe usebenza ngezindlela ezimbili ezihlukene kodwa ezigcwalisanayo ukuze wehlise umfutho wegazi lakho ngempumelelo. Cabanga ngayo njengendlela enezinhlangothi ezimbili ekhomba umfutho wegazi ophezulu emazingeni amaningi.

Ingxenye ye-enalapril ivimba i-enzyme ebizwa nge-ACE (i-angiotensin-converting enzyme) emzimbeni wakho. Le enzyme ngokuvamile isiza ekukhiqizeni i-hormone eqinisa imithambo yegazi futhi ikhuphule umfutho wegazi. Ngokuvimba le enzyme, i-enalapril ivumela imithambo yakho yegazi ukuthi iphumule futhi yande, okwenza kube lula ukuthi igazi ligeleze ngayo.

Khonamanjalo, i-hydrochlorothiazide isebenza ezinso zakho ukusiza ukususa usawoti namanzi amaningi emzimbeni wakho ngokwandisa ukuchama. Lapho kunoketshezi oluncane emithanjeni yakho yegazi, kuba nomfutho omncane odongeni lwemithambo. Lokhu kudala umthwalo olula enhliziyweni yakho ukuthi iphamphe.

Ngokubambisana, lezi zenzo ezimbili zenza ukwehla okukhulu komfutho wegazi kunanoma yimuphi umuthi ongafinyelela wona uwedwa. Le nhlanganisela ithathwa njengeqinile ngokulinganisela futhi ivame ukunikezwa uma imithi eyodwa ingasebenzi ngokwanele.

Kufanele Ngiyithathe Kanjani I-Enalapril kanye ne-Hydrochlorothiazide?

Thatha lo muthi njengoba nje udokotela wakho ekuyala ngayo, ngokuvamile kanye ngosuku ekuseni. Ungayithatha ngaphandle noma ngaphandle kokudla, kodwa ukuyithatha nokudla kungasiza ukunciphisa ukuphazamiseka kwesisu uma uhlangabezana nanoma yikuphi.

Gwinya ithebhulethi yonke ngengilazi yamanzi egcwele. Ungayigxobi, uhlafune, noma uyihlukanise ithebhulethi ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze kanjalo. Ukuyithatha ngesikhathi esifanayo nsuku zonke kusiza ukugcina amazinga aqhubekayo omuthi emzimbeni wakho.

Njengoba lo muthi uqukethe i-diuretic, ukuyithatha ekuseni kuvame ukuba ngcono. Lesi sikhathi sisiza ukuvimbela ukuvama kokuchama ebusuku okungaphazamisa ukulala kwakho. Uma udinga ukuyithatha kabili ngosuku, udokotela wakho ngokuvamile uzoncoma imithamo yasekuseni nasekuseni kakhulu.

Kubalulekile ukuqhubeka nokuthatha lo muthi ngisho noma uzizwa kahle. Umfutho wegazi ophezulu ngokuvamile awubangeli izimpawu, ngakho ungase ungazizwa uhlukile lapho umfutho wegazi lakho uphakeme. Ungayeki ukuthatha umuthi ngaphandle kokukhuluma nodokotela wakho kuqala, njengoba ukuyeka kungazelelwe kungabangela umfutho wegazi lakho ukuthi ukhuphuke ngendlela eyingozi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Enalapril kanye ne-Hydrochlorothiazide?

Abantu abaningi badinga ukuthatha lo muthi isikhathi eside ukuze bagcine umfutho wegazi labo ulawulwa. Umfutho wegazi ophezulu ngokuvamile uyisimo esingapheli esidinga ukuphathwa okuqhubekayo kunokwelashwa kwesikhashana.

Udokotela wakho uzoqapha impendulo yakho emuthini ngokuhlola umfutho wegazi njalo kanye nokuhlolwa kwegazi. Lokhu kuqokwa kusiza ukunquma ukuthi umuthi usebenza ngempumelelo yini nokuthi ngabe kudingeka yini ukulungiswa komthamo. Abantu abaningi baqala ukubona ukuthuthuka komfutho wegazi phakathi kwama-2-4 amaviki ekuqaleni kokwelashwa.

Abanye abantu bangase bagcine behlisa umthamo wemithi yabo noma bashintshe ekwelashweni okuhlukile uma umfutho wabo wegazi ulawulwa kahle futhi benza izinguquko ezinkulu zokuphila. Kodwa-ke, lesi sinqumo kufanele senziwe ngaso sonke isikhathi ngesiqondiso sikadokotela wakho kanye nokubhekwa ngokucophelela.

Ungayeki ukuthatha lo muthi ngokuzumayo, ngisho noma ukufundwa komfutho wakho wegazi kuthuthukile. Ukuyeka kungazelelwe kungabangela umphumela oyingozi lapho umfutho wakho wegazi unyuka ngaphezu kwalokho obunjalo ngaphambi kokwelashwa. Uma udinga ukuyeka umuthi, udokotela wakho uzokwehlisa kancane umthamo wakho ngokuhamba kwesikhathi.

Yiziphi Imiphumela Eceleni ye-Enalapril ne-Hydrochlorothiazide?

Njengayo yonke imithi, le nhlanganisela ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle. Ukuqonda okulindelekile kungakusiza ukuthi uzizwe ulungiseleleke kakhulu futhi wazi ukuthi ungaxhumana nini nodokotela wakho.

Imiphumela emibi evame kakhulu ongase uyithole ngokuvamile imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi:

• Isiyezi noma ukukhathala, ikakhulukazi uma usukuma ngokushesha
• Ukukhwehlela okomile okungabonakali kuphela
• Ukunyuka kokuchama, ikakhulukazi emasontweni ambalwa okuqala
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile
• Ikhanda
• Isicanucanu noma isisu esibuhlungu
• Imisipha eqinile noma ubuthakathaka

Le miphumela emibi ejwayelekile ivame ukuba ngaphansi kokukhathaza njengoba umzimba wakho ujwayela umuthi. Uma ziqhubeka noma ziba nenkinga, khuluma nodokotela wakho mayelana nokulungiswa okungenzeka.

Imiphumela emibi engathi sína ayivamile kodwa idinga ukunakekelwa kwezempilo ngokushesha. Lokhu kungabandakanya:

• Ukunqika okukhulu noma ukuquleka
• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Ukuvuvukala kobuso bakho, izindebe, ulimi, noma umphimbo
• Ukuqubuka kwesikhumba okukhulu noma ukuluma
• Ukuphefumula kanzima noma ukugwinya
• Isicanucanu esikhulu, ukuhlanza, noma isifo sohudo
• Izimpawu zezinkinga zezinso njengokuncipha komchamo noma ukuvuvukala emilenzeni

Ngokuvamile, abanye abantu bangase babe nemiphumela engavamile efana nezinguquko ekunambithekeni, ukulahlekelwa izinwele, noma ukuzwela elangeni. Lokhu kuvame ukubuyiseka uma umuthi uyekiswa, kodwa kufanele uxoxe nganoma yiziphi izimpawu ezikhathazayo nodokotela wakho.

Ubani Ongafanele Athole i-Enalapril ne-Hydrochlorothiazide?

Lo muthi awulungelwe wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuwubhala. Izimo nezimo ezithile zenza le nhlanganisela ibe yingozi noma ingasebenzi kahle.

Akufanele uthathe lo muthi uma ukhulelwe noma uhlela ukukhulelwa. Zombili lezi zinto zingalimaza umntwana osakhula, ikakhulukazi ngesikhathi sesibili nesesithathu sokukhulelwa. Uma ukhulelwa ngenkathi uthatha lo muthi, xhumana nodokotela wakho ngokushesha ukuze uxoxe ngezindlela eziphephile.

Abantu abanezimo ezithile zezokwelapha badinga ukugwema le nhlanganisela noma bayisebenzise ngokuqapha okukhulu:

• Isifo sezinso esibi noma ukuhluleka kwezinso
• Isifo sesibindi noma i-cirrhosis
• Umlando we-angioedema (ukuqubuka okukhulu kobuso, izindebe, noma umphimbo)
• Ukuhluleka kwenhliziyo okukhulu
• Isifo sikashukela esinokuhlushwa yizinso
• I-Lupus noma ezinye izimo ze-autoimmune
• I-Gout noma amazinga aphezulu e-uric acid

Udokotela wakho uzobheka neminye imithi oyithathayo, njengoba eminye ingasebenzisana ngendlela eyingozi nale nhlanganisela. Qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi kadokotela, imithi etholakala ngaphandle kwe-oda, kanye nezithasiselo ozisebenzisayo.

Uma unesifo sikashukela, isifo sezinso, noma izinkinga zenhliziyo, udokotela wakho angase akunikeze lo muthi kodwa uzokuhlola eduze ngemihlolokhono yegazi ejwayelekile nokuhlolwa.

Amagama Omkhiqizo we-Enalapril ne-Hydrochlorothiazide

Lo muthi ohlanganisiwe utholakala ngaphansi kwamagama amaningi omkhiqizo, i-Vaseretic iyona eyaziwa kakhulu. Amanye amagama omkhiqizo afaka i-Prinzide, nakuba ukutholakala kungahluka kuye ngendawo yakho nekhemisi.

Ungase futhi uthole izinguqulo ezivamile zalolu hlobo, eziqulathe izithako ezifanayo ezisebenzayo kodwa ngokuvamile zibiza kancane. Imithi ejwayelekile kumele ihlangabezane nezindinganiso ezifanayo zokuphepha nokusebenza njengemithi enegama lomkhiqizo, ngakho ithembeke ngokulinganayo ekwelapheni isimo sakho.

Lapho uthatha umuthi wakho, ungase uqaphele ukuthi amaphilisi abukeka ehlukile ngenyanga nenyanga uma ikhemisi lakho lishintsha phakathi kwabakhiqizi abahlukene. Lokhu kuvamile futhi akuthinti ukusebenza komuthi. Izithako ezisebenzayo zihlala zinjalo kungakhathaliseki ukuthi ngubani umkhiqizi.

Ezinye izindlela ze-Enalapril ne-Hydrochlorothiazide

Uma le nhlanganisela ingasebenzi kahle kuwe noma idala imiphumela engathandeki, ezinye izindlela ziyatholakala. Udokotela wakho angase asikisele izinhlanganisela ezihlukene noma akushintshele emakilasini ahlukene ngokuphelele emithini yokwehlisa umfutho wegazi.

Ezinye izinhlanganisela ze-ACE inhibitor zifaka i-lisinopril ene-hydrochlorothiazide noma i-benazepril ene-hydrochlorothiazide. Lezi zisebenza ngendlela efanayo kodwa zingase zibekezelelwe kangcono ngabanye abantu. Izinhlanganisela ze-ARB (angiotensin receptor blocker) njenge-losartan ene-hydrochlorothiazide zinikeza enye inketho enezinkinga ezimbalwa.

Abanye abantu benza kangcono ngama-calcium channel blockers ahlanganiswe nama-diuretics, njenge-amlodipine ene-hydrochlorothiazide. Ama-beta-blockers ahlanganiswe nama-diuretics amelela enye indlela yokulawula umfutho wegazi.

Kulabo bantu abangakwazi ukumelana nemithi yokukhipha amanzi emzimbeni, udokotela wakho angase akunikeze i-ACE inhibitor enesithiyo sesiteshi se-calcium esikhundleni salokho. Okubalulekile ukuthola inhlanganisela efanele elawula ngempumelelo umfutho wegazi lakho ngenkathi inciphisa imiphumela emibi.

Ingabe i-Enalapril ne-Hydrochlorothiazide Ingcono Kune-Lisinopril?

Kokubili i-enalapril/hydrochlorothiazide ne-lisinopril bangabeqembu elifanayo lemithi futhi basebenza ngendlela efanayo ukulawula umfutho wegazi. Ukukhetha phakathi kwabo kuvame ukuncika ezintweni zomuntu ngamunye njengokuthi ukumelana kahle kangakanani nomuthi ngamunye kanye nezidingo zakho zempilo ezithile.

I-Lisinopril yodwa ivame ukunqunywa njengokwelashwa kokuqala komfutho wegazi ophezulu, kuyilapho inhlanganisela ye-enalapril/hydrochlorothiazide ivame ukusetshenziswa lapho imithi eyodwa ingasebenzi ngokwanele. Le nhlanganisela ingase ifaneleke kakhulu uma udinga inzuzo eyengeziwe ye-diuretic.

Abanye abantu bathola ukuthi bayamelana ne-ACE inhibitor eyodwa kangcono kunenye, yize isebenza ngendlela efanayo. Isibonelo, uma i-lisinopril ibangela ukukhwehlela okuqhubekayo, udokotela wakho angase akuqhubekisele ku-enalapril, okungenzeka ukuthi akunakwenzeka ukuthi kubangele le miphumela emibi kwabanye abantu.

Ukukhetha

Noma kunjalo, isithako se-hydrochlorothiazide ngezinye izikhathi singathinta amazinga kashukela egazini, okungenzeka ukuthi awenze abe phezulu kancane. Udokotela wakho uzoqapha ushukela wakho wegazi eduze uma uqala lo muthi futhi kungase kudingeke alungise imithi yakho yesifo sikashukela ngokufanele.

Abantu abanesifo sikashukela kanye nesifo sezinso badinga ukuqashwa ngokucophelela, njengoba zombili lezi zimo zingathinta indlela umzimba wakho osebenzisa ngayo lo muthi. Ukuhlolwa kwegazi okujwayelekile kusiza ukuqinisekisa ukuthi umuthi usebenza ngokuphepha nangempumelelo.

Ngingenzani Uma Ngisebenzisa Ngengozi I-Enalapril ne-Hydrochlorothiazide Eningi Kakhulu?

Uma ngengozi uthatha ngaphezu komthamo wakho obekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela ukwehla okuyingozi komfutho wegazi, okuholela ekugqwaleni, ukuquleka, noma ezinye izinkinga ezingathi sína.

Izimpawu zokweqisa zingabandakanya isiyezi esikhulu, ukukhathala okukhulu, isicanucanu, ukuhlanza, noma ukuzizwa sengathi ungaquleka. Ungalindi ukubona ukuthi izimpawu ziyavela yini - thola usizo lwezokwelapha ngokushesha uma uthathe okuningi.

Ngesikhathi ulinde usizo lwezokwelapha, hlala phansi noma ulale phansi ukuze uvimbele ukuwa uma uzizwa unesiyezi. Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo ukuthi wenze kanjalo ngumhlinzeki wezempilo. Gcina ibhodlela lomuthi nawe ukuze ubonise abasebenzi bezokwelapha ukuthi uthathe ini nokuthi uthathe malini.

Ngingenzani Uma Ngiphuthelwa Umthamo We-Enalapril ne-Hydrochlorothiazide?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, ngaphandle kwalapho sekuyisikhathi esicishe sibe sesikhathini sakho esilandelayo esihleliwe. Kulokho, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe.

Ukuphuthelwa umthamo ngezikhathi ezithile ngeke kubangele ukulimala ngokushesha, kodwa zama ukuthatha imithi yakho ngokuqhubekayo ukuze uthole ukulawulwa okungcono komfutho wegazi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha i-alamu yefoni noma ukusebenzisa umhleli wamaphilisi ukukusiza ukuthi ukhumbule.

Uma uphuthelwa imithamo kaningi, khuluma nodokotela wakho ngamasu okuthuthukisa ukunamathela emithini. Kwesinye isikhathi ukushintshela esimisweni esihlukile sokulinganisa noma uhlobo lomuthi kungasiza ukwenza kube lula ukukhumbula.

Ngingayeka nini ukuthatha i-Enalapril ne-Hydrochlorothiazide?

Ungalokothi uyeke ukuthatha lo muthi ngaphandle kwesiqondiso sikadokotela wakho, ngisho noma uzizwa kahle noma ukufundwa kwengcindezi yakho yegazi kuthuthukile. Umfutho wegazi ophezulu ngokuvamile uyisimo sempilo yonke esidinga ukuphathwa okuqhubekayo.

Udokotela wakho angase acabange ukunciphisa umthamo wakho noma ashintshe imithi uma umfutho wegazi lakho ulawulwe kahle isikhathi eside futhi wenze izinguquko ezinkulu zokuphila. Kodwa-ke, lesi sinqumo sidinga ukuqapha ngokucophelela futhi akufanele senziwe wedwa.

Uma udinga ukuyeka umuthi ngenxa yemiphumela emibi noma ezinye izinkinga zempilo, udokotela wakho uzonciphisa kancane umthamo wakho ngokuhamba kwesikhathi. Lokhu kuvimbela ukukhuphuka okuyingozi komfutho wegazi okungenzeka uma uyeka kungazelelwe.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Enalapril ne-Hydrochlorothiazide?

Ungaphuza utshwala ngokulinganisela ngenkathi uthatha lo muthi, kodwa qaphela kakhulu imiphumela ehlanganisiwe. Kokubili utshwala kanye nalo muthi kunganciphisa umfutho wegazi, ngakho ukuphuza kungase kwandise ingozi yakho yokuba nesiyezi noma ukuquleka.

Qala ngezilinganiso ezincane zotshwala kunokujwayelekile ukuze ubone ukuthi umzimba wakho usabela kanjani. Ingxenye ye-diuretic nayo ingakhuphula ingozi yokuphelelwa amanzi emzimbeni, okungase kuqiniswe utshwala. Qiniseka ukuthi uphuza amanzi amaningi uma ukhetha ukuphuza utshwala.

Uma uqaphela ukwanda kwesiyezi, ukukhathala, noma ezinye izimpawu ezikhathazayo lapho uphuza, kungcono ukugwema utshwala noma uxoxe ngemikhawulo ephephile nodokotela wakho. Abanye abantu bathola ukuthi badinga ukugwema utshwala ngokuphelele ngenkathi bethatha lo muthi.