Yini i-Lubiprostone: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Lubiprostone iyimithi kadokotela esiza ukwelapha ukuqunjelwa okungamahlalakhona kanye nezifo ezithile zamathumbu ngokwandisa uketshezi emathunjini akho. Cabanga ngayo njengomsizi omnene okwenza kube lula emzimbeni wakho ukuba abe nokuhamba kwamathumbu okuvamile, okunethezekile lapho izinqubo zemvelo zingasebenzi njengoba kufanele.

Le mithi ingeyodwa ekilasini elibizwa ngokuthi ama-chloride channel activators, asebenza ngendlela ehlukile kunama-laxatives ajwayelekile. Esikhundleni sokucindezela amathumbu akho ukuba aqhubeke, i-lubiprostone isiza amathumbu akho ukuthi akhiqize uketshezi olwengeziwe ngokwemvelo, okwenza indle ithambe futhi ibe lula ukudlula.

Yini i-Lubiprostone Esetshenziselwa Yona?

I-Lubiprostone iphatha ukuqunjelwa okungamahlalakhona okungaziwa, okusho ukuqunjelwa kwesikhathi eside ngaphandle kwembangela ecacile. Udokotela wakho angase akubhalele lokhu uma ubulokhu ulwa nokuhamba kwamathumbu okungavamile noma okunzima amasonto noma izinyanga.

Lo muthi futhi usiza abantu abanesifo samathumbu esicasulayo esinokuqunjelwa (IBS-C), isimo lapho ukuqunjelwa kuza nobuhlungu besisu nokuqumba. Ngaphezu kwalokho, ingelapha ukuqunjelwa okubangelwa yi-opioid kubantu abadala abanezinhlungu ezingamahlalakhona ezingezona umdlavuza abathatha imithi ye-opioid.

Ngemva kokusho lokho, i-lubiprostone ayihloselwe ukuqunjelwa okwenzeka ngezikhathi ezithile wonke umuntu akuzwayo ngezikhathi ezithile. Umhlinzeki wakho wokunakekelwa kwezempilo uzoqonda ukuthi izimpawu zakho zifanele yini le ndlela ethile yokwelapha.

Isebenza Kanjani i-Lubiprostone?

I-Lubiprostone isebenza ngokwenza imisele ye-chloride emangqamuzaneni akho amathumbu, okwandisa inani loketshezi emathunjini akho. Lokhu ketshezi olwengeziwe lusiza ukuthambisa indle futhi kuyenze ihambe kalula ngohlelo lwakho lokugaya ukudla.

Lokhu kuthathwa njengomuthi onamandla aphakathi nendawo onikeza ukukhululeka okuqhubekayo, okuqhubekayo kunemiphumela esheshayo. Ngokungafani nama-laxatives akhuthazayo angabangela ukuqaqamba, i-lubiprostone isebenza ngobumnene ngokusekela izinqubo zemvelo zokugaya ukudla zomzimba wakho.

Umuthi ngokuvamile uqala ukusebenza kungakapheli amahora angama-24, nakuba abanye abantu bengase baqaphele ukuthuthuka ngokushesha. Wenzelwe ukuhlinzeka ngosizo oluqhubekayo kunokulungisa okusheshayo ukuqunjelwa okwenzeka ngezikhathi ezithile.

Kufanele Ngiyithathe Kanjani I-Lubiprostone?

Thatha i-lubiprostone ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile kabili ngosuku ngokudla namanzi. Ukuyithatha ngokudla kusiza ukunciphisa ithuba lesicanucanu, okuyisimo esivamile esivela njengomphumela.

Gwinya amaphilisi wonke ngaphandle kokuwachoboza, ukuwahlafuna, noma ukuwavula. Umuthi wenzelwe ukuthi ukhululwe kancane ohlelweni lwakho lokugaya ukudla, ngakho ukuqhekeza iphilisi kungathinta indlela osebenza ngayo.

Uma ukhohlwa umthamo, wuthatha ngokushesha lapho ukhumbula, kodwa ungaphindi uma sekuseduze isikhathi somthamo wakho olandelayo. Ukuqina kubaluleke kakhulu kunokulungisa imithamo ephuthelwe, ngakho zama ukuyithatha ngezikhathi ezifanayo nsuku zonke.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Lubiprostone?

Ubude bokwelashwa buyahluka kuye ngesimo sakho esithile nokuthi usabela kahle kangakanani emuthini. Abanye abantu bayayidinga amasonto ambalwa, kanti abanye bangayithatha izinyanga noma isikhathi eside.

Udokotela wakho uzoqapha inqubekela phambili yakho futhi alungise uhlelo lokwelashwa njengoba kudingeka. Ezimweni ezingamahlalakhona njenge-IBS-C, ungase udinge ukwelashwa kwesikhathi eside ukuze ugcine ukusebenza kwamathumbu okunethezekile.

Ungayeki ukuthatha i-lubiprostone ngokuzumayo ngaphandle kokukhuluma nomhlinzeki wakho wezempilo kuqala. Bangase bafune ukunciphisa umthamo wakho kancane kancane noma bakushintshele kwenye indlela yokwelapha.

Yiziphi Imiphumela Eceleni Ye-Lubiprostone?

Imiphumela emibi evame kakhulu ngokuvamile imnene futhi ivame ukuthuthuka njengoba umzimba wakho uzivumela emuthini. Ukuqonda okulindelekile kungakusiza ukuthi uzizwe uqiniseka ngokuphathwa kwakho.

Imiphumela emibi ongase uyithole ihlanganisa:

• Isicanucanu (ukuthatha ngokudla kuyasiza ukunciphisa lokhu)
• Ukuphuma kwendle noma izitulo ezixekile
• Ubuhlungu besisu noma ukuqunjelwa
• Igesi noma i-flatulence
• Ikhanda elibuhlungu
• Isiyezi

Lezi zimpawu zivame ukuncipha ngemva kwezinsuku ezimbalwa zokuqala zokwelashwa. Uma isicanucanu siqhubeka, ukudla ukudla okulula ngaphambi kokuthatha imithi yakho kungasiza.

Imiphumela engavamile kodwa ebucayi edinga ukunakekelwa kwezempilo ngokushesha. Lokhu kufaka phakathi ubuhlungu obukhulu besisu, ubunzima bokuphefumula, ukuqina kwesifuba, noma izimpawu zokungezwani komzimba njengokuqubuka noma ukuvuvukala.

Abanye abantu bahlangabezana nalokho okubizwa ngokuthi "i-dyspnea," okuyisifutho sokuphefumula esingenzeka kungakapheli ihora ngemva kokuthatha imithi. Uma lokhu kwenzeka, xhumana nodokotela wakho ngokushesha.

Ubani Ongafanele Athatha I-Lubiprostone?

Abantu abathile kufanele bagweme i-lubiprostone ngenxa yokukhathazeka ngokuphepha. Udokotela wakho uzobuyekeza umlando wakho wezokwelapha ngokucophelela ngaphambi kokukuchazela le mithi.

Akufanele uthathe i-lubiprostone uma wazi ukuthi unokuvaleka kwamathumbu noma isifo sohudo esibi. Imithi yandisa uketshezi emathunjini akho, okungase kwenze lezi zimo zibe zimbi.

Abantu abanezinkinga ezinkulu zesibindi bangase badinge ukulungiswa komthamo noma ukwelashwa okuhlukile. Ngaphezu kwalokho, uma unokungezwani komzimba ku-lubiprostone noma kunoma yiziphi izithako zayo, uzodinga omunye umuthi.

Abesifazane abakhulelwe kufanele baxoxe ngezingozi nezinzuzo nomhlinzeki wabo wezempilo, njengoba imithi ingase ingafaneleki ngesikhathi sokukhulelwa. Omama abancelisa ngamabele nabo badinga isiqondiso sezokwelapha ngaphambi kokuqala ukwelashwa.

Amagama Omkhiqizo we-Lubiprostone

I-Lubiprostone itholakala ngaphansi kwegama lomkhiqizo elithi Amitiza e-United States. Lolu uhlobo oluvame kakhulu oluchazwayo lwemithi.

Izinhlobo ezivamile zingase zitholakale, kodwa ziqukethe isithako esifanayo esisebenzayo futhi zisebenza ngendlela efanayo. Umuthi wakho wemithi angachaza noma iyiphi imininingwane ehlukile phakathi kwezinketho zomkhiqizo nezivamile.

Hlala njalo uxhumana nomhlinzeki wakho wezempilo ngaphambi kokushintsha phakathi kwezinhlobo ezahlukene ze-lubiprostone ukuqinisekisa ukuthi uthola umthamo ofanele kanye nokwakheka okudingayo.

Ezinye izindlela zokwelapha i-Lubiprostone

Eminye imithi eminingi ingelapha ukuqunjelwa okungapheli kanye ne-IBS-C uma i-lubiprostone ingakulungele. Udokotela wakho angasiza ekutholeni ukuthi iyiphi inketho engasebenza kahle esimweni sakho esithile.

Ezinye izinketho zokubhala imithi zihlanganisa i-linaclotide (Linzess), i-plecanatide (Trulance), kanye ne-tegaserod (Zelnorm). Ngayinye isebenza ngendlela ehlukile futhi ingase ilungele izinhlobo ezithile zokuqunjelwa.

Ezinye izindlela zokwelapha ezingathengiswa ngaphandle kwemvume kadokotela njenge-polyethylene glycol (MiraLAX) noma izithasiselo ze-fiber zingase zifanelekele amacala alula. Kodwa-ke, ukuqunjelwa okungapheli kuvame ukudinga ukwelashwa ngemithi kadokotela ukuze kulawulwe isikhathi eside ngempumelelo.

Ingabe i-Lubiprostone ingcono kune-Linzess?

Kokubili i-lubiprostone ne-Linzess (linaclotide) ziyizindlela zokwelapha ezisebenzayo zokuqunjelwa okungapheli kanye ne-IBS-C, kodwa zisebenza ngezindlela ezahlukene. Ukukhetha okuthi "kungcono" kuncike ezimpawini zakho ngazinye kanye nomlando wezokwelapha.

I-Lubiprostone ivame ukubangela ukuhuda okuncane kune-Linzess, okuyenza ibe yindlela enhle uma uthambekele ezitulweni ezixekile. Kodwa-ke, i-Linzess ingase isebenze kahle kubantu abahlupheka nobuhlungu obukhulu besisu.

Udokotela wakho uzocabangela izinto ezinjengeminye imithi yakho, ukusebenza kwezinso, nezimpawu ezithile lapho ekhetha phakathi kwalezi zinketho. Abanye abantu bangase badinge ukuzama zombili ukuze bathole okusebenza kahle emzimbeni wabo.

Imibuzo Evame Ukubuzwa Mayelana ne-Lubiprostone

Ingabe i-Lubiprostone iphephile kubantu abanezifo zenhliziyo?

I-Lubiprostone ngokuvamile ithathwa njengephephile kubantu abanezifo zenhliziyo, kodwa kufanele ngaso sonke isikhathi wazise udokotela wakho nganoma yiziphi izinkinga zenhliziyo ngaphambi kokuqala ukwelashwa. Umuthi ngokuvamile awuthinti izinga lenhliziyo noma umfutho wegazi ngendlela enkulu.

Noma kunjalo, ukuphefumula okuncane okuhlangenwe nakho ngabanye abantu kungase kukhathaze uma unezinkinga zenhliziyo noma yamaphaphu. Umhlinzeki wakho wezempilo uzohlola izinzuzo ngokumelene nanoma yiziphi izingozi ezingaba khona ngokusekelwe esimweni sakho esithile.

Kufanele ngenzeni uma ngithatha i-Lubiprostone eningi ngengozi?

Uma ngengozi uthatha i-lubiprostone eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela isifo sohudo esibi, ukushoda kwamanzi emzimbeni, nokungalingani kwama-electrolyte.

Ungazami ukuzenza uhlanze noma uthathe eminye imithi ukuze ulwe nokweqisa. Kunalokho, phuza amanzi amaningi futhi ufune ukunakekelwa kwezempilo ukuze uqinisekise ukuthi uhlala unamanzi kahle futhi ulinganiselwe.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Lubiprostone?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, kodwa kuphela uma kungasondeli isikhathi somthamo wakho olandelayo ohleliwe. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise okungaphuthelwanga.

Ukuphuthelwa umthamo ngezikhathi ezithile ngeke kukulimaze, kodwa zama ukugcina isimiso esiqhubekayo ukuze uthole imiphumela engcono kakhulu. Ukusetha izikhumbuzi zocingo noma ukugcina imithi yakho endaweni ebonakalayo kungakusiza ukuthi ukhumbule.

Ngingayeka nini ukuthatha i-Lubiprostone?

Yeka kuphela ukuthatha i-lubiprostone uma udokotela wakho ekutshela ukuthi kuphephile ukwenza kanjalo. Ukuyeka kungazelelwe kungase kubangele ukuthi izimpawu zakho zokuqunjelwa zibuye, ikakhulukazi uma unesimo esingamahlala-mandla.

Umhlinzeki wakho wezempilo uzokusiza ukuthi unqume ukuthi uzuze nini ukusebenza kahle kwamathumbu nokuthi ngabe udinga ukuqhubeka nokwelashwa. Bangase banciphise kancane kancane umthamo wakho noma bakusize ukuthi ushintshele kwamanye amaqhinga okuphatha.

Ngingayithatha i-Lubiprostone neminye imithi?

I-Lubiprostone ngokuvamile ingathathwa neminye imithi eminingi, kodwa ngaso sonke isikhathi yazisa udokotela wakho ngakho konke okuthathayo, okuhlanganisa imithi etholakala ngaphandle kwekhawunta kanye nezithasiselo.

Ezinye izidakamizwa zingase zihlangane ne-lubiprostone noma zithinte ukuthi isebenza kahle kangakanani. Umkhemisi wakho angahlola nokuthi kungenzeka yini ukuthi kuxhumane futhi aphendule imibuzo mayelana nesikhathi sokuthatha imithamo yakho usuku lonke.