Yini i-Methsuximide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Methsuximide iyimithi elwa nokuthuthumela esiza ukulawula ukuthuthumela okungabikho, okwaziwa nangokuthi ukuthuthumela kwe-petit mal. Lokhu kuyizigameko ezimfushane lapho ungase ubonakale sengathi "uyazihlukanisa" noma ubuke ngamehlo abanzi imizuzwana embalwa. Le mithi ingeyeqembu elibizwa ngokuthi ama-succinimides, asebenza ngokuthulisa izimpawu zikagesi ezingaphezu kwamandla ebuchosheni bakho ezingabangela ukuthuthumela.

Yini i-Methsuximide?

I-Methsuximide iyimithi kadokotela eyenzelwe ngqo ukwelapha ukuthuthumela okungabikho kubantu abanesithuthwane. Yilokho odokotela abakubiza ngokuthi i-anticonvulsant noma i-anti-epileptic drug. Umuthi usebenza ngokugxila kumaseli athile obuchopho aba nokuthuthuka ngokweqile ngesikhathi sokuthuthumela.

Le mithi isisize abantu ukuthi balawule ukuthuthumela kwabo amashumi eminyaka. Ithathwa njengokwelashwa okukhethekile, okusho ukuthi udokotela wakho cishe uzozama eminye imithi kuqala ngaphambi kokukuyala i-methsuximide. Umuthi uza ngesimo samaphilisi futhi uthathwa ngomlomo.

Isetshenziselwani i-Methsuximide?

I-Methsuximide isetshenziswa ikakhulukazi ukulawula ukuthuthumela okungabikho kubantwana nakubantu abadala. Lokhu kuthuthumela kubangela ukuthi ulahlekelwe ngokuqwashisa okufushane lapho ungase ubonakale sengathi uyaphupha noma ubuka emkhathini. Ngesikhathi salezi zigameko, awuqapheli okukuzungezile futhi ngeke uphendule uma othile ezama ukuthola ukunakwa kwakho.

Udokotela wakho angase akuyalele i-methsuximide uma ezinye izindlela zokwelapha zokuqala zingasebenzi kahle kuwe. Ngezikhathi ezithile isetshenziswa kanye neminye imithi yokuthuthumela ukuhlinzeka ngokuqondisa okungcono. Umgomo uwukunciphisa imvamisa namandla okuthuthumela kwakho ukuze ukwazi ukuphila impilo yansuku zonke ejwayelekile.

Ezimweni ezingavamile, odokotela bangase bacabangele i-methsuximide kwezinye izinhlobo zokuthuthumela lapho ukwelashwa okujwayelekile kungasebenzi. Kodwa-ke, lokhu akuvamile futhi kungenzeka kuphela ngaphansi kokuqondiswa kwezokwelapha okucophelelayo.

Isebenza kanjani i-Methsuximide?

IMethsuximide isebenza ngokuvimba iziteshi ezithile ze-calcium emangqamuzaneni akho obuchopho. Cabanga ngalezi ziteshi njengeminyango emincane evumela amasignali kagesi ukuthi adlule. Uma le minyango iba matasa kakhulu, ingabangela ukuquleka.

Umuthi uqondise ngqo iziteshi ze-calcium ze-T-type, ezihileleke ikakhulukazi ekuqulekeni okungabikho. Ngokuvimba ingxenye yalezi ziteshi, i-methsuximide isiza ukuvimbela umsebenzi ongajwayelekile kagesi obangela ukuthi ubuchopho bakho bu "phuthelwe" ngesikhathi sokuquleka.

Lokhu kuthathwa njengomuthi wokulwa nokuquleka onamandla aphakathi nendawo. Awunamandla njengeminye imithi emisha yokulwa nokuquleka, kodwa ingasebenza kahle kakhulu ohlotsheni oluthile lokuquleka olwelapha. Umuthi udinga ukwakheka ohlelweni lwakho ngokuhamba kwesikhathi ukuze ufinyelele ekusebenzeni kwawo okuphelele.

Kufanele Ngiyithathe Kanjani I-Methsuximide?

Thatha i-methsuximide ngendlela eqondile udokotela wakho ayikuyala ngayo, ngokuvamile kanye noma kabili ngosuku. Ungayithatha nokudla noma ngaphandle kokudla, kodwa ukuyithatha nokudla kungasiza ukunciphisa isisu esibuhlungu. Gwinya amaphilisi wonke ngenkomishi yamanzi egcwele.

Zama ukuthatha umuthi wakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo egazini lakho. Lokhu kuvumelana kusiza umuthi ukuthi usebenze ngempumelelo. Uma uyithatha kabili ngosuku, hlukanisa imithamo ngamahora ayi-12.

Ungachobozi, uhlafune, noma uvule amaphilisi, ngoba lokhu kungathinta indlela umuthi omuncwa ngayo. Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho mayelana nezinketho ezingezinye. Ungayeki ukuthatha i-methsuximide ngokuzumayo, ngoba lokhu kungabangela ukuquleka okuyingozi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Methsuximide?

Abantu abaningi abanesithuthwane badinga ukuthatha i-methsuximide izinyanga noma iminyaka ukuze bagcine ukulawulwa kokuquleka. Udokotela wakho uzoqapha inqubekela phambili yakho futhi angase ashintshe uhlelo lwakho lokwelashwa ngokuhamba kwesikhathi. Abanye abantu bangagcina banciphisa umthamo wabo noma bayeke umuthi, kodwa lokhu kumele kwenziwe kancane kancane ngaphansi kokuqondiswa kwezokwelapha.

Ubude bokwelashwa buxhomeke ezintweni eziningi, okuhlanganisa ukuthi umuthi uwalawula kahle kangakanani ukuquleka kwakho nokuthi ngabe unayo imiphumela emibi. Udokotela wakho uzohlola njalo amazinga egazi lakho nempilo yakho yonke ukuqinisekisa ukuthi umuthi usebenza ngokuphepha.

Izingane zingase zikwazi ukuyeka ukuthatha i-methsuximide njengoba zikhula, ikakhulukazi uma zikhula ngaphandle kwesifo sazo sokuquleka. Kodwa-ke, lesi sinqumo kufanele senziwe ngudokotela wakho kuphela ngemuva kokuhlolwa ngokucophelela kwephethini yakho yokuquleka nempilo yonke.

Yini Imiphumela Eceleni Ye-Methsuximide?

Njengayo yonke imithi, i-methsuximide ingabangela imiphumela emibi, yize kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nawa amanye imiphumela emibi ejwayelekile ongase uyithole:

• Isicanucanu nokuphazamiseka kwesisu
• Ukozela noma isiyezi
• Ikhanda
• Ukulahlekelwa isifiso sokudla
• Ukuthimula
• Ukubona okungacacile

Lezi zimpawu zivame ukuba ngaphansi kokuphazamisa ngemuva kwamasonto ambalwa njengoba umzimba wakho ujwayela umuthi.

Abanye abantu bangase babe nemiphumela emibi ekhathazayo edinga ukunakekelwa kwezempilo ngokushesha:

• Ukuqubuka kwesikhumba okukhulu noma imihuzuko
• Ukulimala noma ukopha okungavamile
• Umkhuhlane oqhubekayo noma umphimbo obuhlungu
• Isiyezi esikhulu noma ukuquleka
• Ushintsho lwemizwa noma ukucindezeleka
• Imicabango yokuzibulala

Xhumana nodokotela wakho ngokushesha uma uqaphela noma iyiphi yale miphumela emibi engathi sína.

Imiphumela emibi engavamile kodwa engathi sína ingabandakanya izifo zegazi nezinkinga zesibindi. Udokotela wakho uzokuqapha ngezivivinyo zegazi ezijwayelekile ukuze ubambe lezi zinkinga ekuqaleni. Ngenkathi lezi zinkinga zingavamile, yingakho ukulandela ezokwelapha njalo kubaluleke kangako.

Ubani Ongafanele Athatha I-Methsuximide?

I-Methsuximide ayiphephile kuwo wonke umuntu. Akufanele uthathe lo muthi uma unokungezwani komzimba ne-methsuximide noma eminye imithi ye-succinimide efana ne-ethosuximide.

Abantu abanezimo ezithile zezokwelapha badinga ukuqapha okwengeziwe noma kungenzeka bangakwazi ukuthatha i-methsuximide nakancane:

• Isifo esibi sezinso
• Isifo esibi sesibindi
• Izifo zegazi
• Umlando wokucindezeleka okukhulu noma imicabango yokuzibulala
• I-Porphyria (isifo segazi esingavamile)

Uma unesinye salezi zimo, udokotela wakho uzodinga ukulinganisa izinzuzo nezingozi ngokucophelela kakhulu.

Abesifazane abakhulelwe kufanele basebenzise i-methsuximide kuphela uma kuyimpoqo, njengoba ingalimaza ingane esakhula. Uma uhlela ukukhulelwa noma usuvele ukhulelwe, xoxa ngalokhu nodokotela wakho ngokushesha. Umuthi ungangena obisini lwebele, ngakho omama abancelisayo badinga isiqondiso sezokwelapha.

Amagama Omkhiqizo we-Methsuximide

I-Methsuximide itholakala ngaphansi kwegama lomkhiqizo elithi Celontin. Kodwa-ke, lo mkhiqizo awusatholakali kakhulu emazweni amaningi, okuhlanganisa ne-United States. Imithi eminingi namuhla igcwaliswa ngezinhlobo ezivamile zomuthi.

Ifomu elivamile liqukethe isithako esifanayo esisebenzayo futhi lisebenza ngempumelelo njengenguqulo yegama lomkhiqizo. Umuthi wakho wemithi ungakutshela ukuthi yimuphi umenzi okhiqiza inguqulo ejwayelekile oyitholayo.

Ezinye Izindlela ze-Methsuximide

Uma i-methsuximide ingasebenzi kahle kuwe noma ibangela imiphumela engemihle, udokotela wakho unezinye izinketho eziningana okufanele azicabangele. I-Ethosuximide ivame ukuba yinto yokuqala yokukhetha ekuhlaselweni okungabonakali futhi ihlobene eduze ne-methsuximide.

Ezinye izindlela zokuhlaselwa okungabonakali zihlanganisa:

• I-Valproic acid (Depakote)
• I-Lamotrigine (Lamictal)
• I-Levetiracetam (Keppra)
• I-Topiramate (Topamax)

Udokotela wakho uzokhetha enye indlela engcono kakhulu ngokusekelwe ohlotsheni lwakho oluthile lokuhlaselwa, ubudala, ezinye izimo zempilo, nokuthi usabele kanjani ekwelashweni kwangaphambilini.

Ingabe i-Methsuximide ingcono kune-Ethosuximide?

I-Ethosuximide ngokuvamile ithathwa njengokwelashwa kokuqala kwe-absence seizures, kuyilapho i-methsuximide ivame ukusetshenziswa uma i-ethosuximide ingasebenzi noma ibangela imiphumela engamukeleki. Yomibili imithi isebenza ngendlela efanayo, kodwa i-ethosuximide ifundwe kabanzi.

I-Ethosuximide ivame ukubangela imiphumela emincane futhi inerekhodi elide lokuphepha. Kodwa-ke, abanye abantu basabela kangcono ku-methsuximide, ikakhulukazi uma bengaphumelelanga nge-ethosuximide.

Udokotela wakho uzocabangela isimo sakho ngasinye, okuhlanganisa iphethini yakho yokuhlaselwa, iminyaka, eminye imithi, kanye nezimpendulo zokwelashwa zangaphambilini lapho ekhetha phakathi kwalezi zinketho. Akukho emithini engcono ngokujwayelekile - kuncike kulokho okusebenza kahle kakhulu esimweni sakho esithile.

Imibuzo Evame Ukubuzwa Mayelana ne-Methsuximide

Ingabe i-Methsuximide iphephile ezinganeni?

Yebo, i-methsuximide ingasetshenziswa ngokuphepha ezinganeni uma inikezwe futhi iqashwe yi-neurologist yezingane noma uchwepheshe we-epilepsy. Izingane zivame ukudinga imithamo ehlukile kunabadala, futhi ukusabela kwazo emuthini kungase kwehluke.

Abazali kufanele baqaphele noma yiziphi izinguquko ekuziphatheni kwengane yabo, imizwa, noma ukusebenza kahle emfundweni ngenkathi bethatha i-methsuximide. Ukuqokwa okuvamile kokulandela ngemuva kubalulekile ukuqinisekisa ukuthi umuthi usebenza kahle futhi awubangeli imiphumela emibi.

Ngingenzani uma ngiphuzile i-Methsuximide eningi ngengozi?

Uma uphuza i-methsuximide eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Izimpawu zokweqisa zingase zihlanganise ukozela okukhulu, ukudideka, ubunzima bokuphefumula, noma ukulahlekelwa ukwazi.

Ungalindi ukubona ukuthi izimpawu ziyavela yini - funa ukunakekelwa kwezempilo ngokushesha. Gcina ibhodlela lomuthi nawe ukuze abahlinzeki bezempilo bakwazi ukubona kahle ukuthi yini nokuthi ungakanani okuthathile.

Ngingenzani uma ngiphuthelwa umthamo we-Methsuximide?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Uma kunjalo, weqa umthamo ophuthelwe bese uqhubeka nesheduli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungandisa ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi ukukusiza ukuthi uhlale emgwaqeni.

Ngingayeka nini ukuthatha i-Methsuximide?

Ungalokothi uyeke ukuthatha i-methsuximide ngokuzumayo noma ngaphandle kwesiqondiso sikadokotela wakho. Ukuyeka imithi yokulwa nokuthuthumela ngokuphazima kweso kungabangela ukuthuthumela okuyingozi, ngisho noma ungakaze ube nokuthuthumela isikhathi eside.

Udokotela wakho uzonciphisa kancane kancane umthamo wakho emasontweni amaningana noma izinyanga uma enquma ukuthi kuphephile ukuyeka imithi. Le nqubo ibizwa ngokuthi ukunciphisa, futhi ivumela ubuchopho bakho ukuthi buvumelane ngokuphepha emazingeni aphansi emithi.

Ngingashayela ngesikhathi ngithatha i-Methsuximide?

Ukushayela ngenkathi uthatha i-methsuximide kuncike ekutheni ukuthuthumela kwakho kulawulwa kahle kangakanani nokuthi imithi ikwenza yini ukozela. Abantu abaningi bangashayela ngokuphepha uma ukuthuthumela kwabo kulawulwa kahle futhi sebeqhelile emithini.

Noma kunjalo, kufanele ugweme ukushayela uma uzwa isiyezi, ukozela, noma umbono ongacacile ngenxa yemithi. Xhumana nodokotela wakho mayelana nokuthi kuphephile nini ukuqhubeka nokushayela, futhi uqaphele imithetho yakho yendawo mayelana nokushayela ngesithuthumela.