Yini i-Milnacipran: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Milnacipran iyimithi kadokotela esiza ukuphatha izimo zobuhlungu ezingapheli, ikakhulukazi i-fibromyalgia. Ingaphansi kohlobo lwemithi ebizwa ngokuthi ama-serotonin-norepinephrine reuptake inhibitors (SNRIs), esebenza ngokulungisa amakhemikhali athile obuchopho athinta kokubili imizwa nokuqonda ubuhlungu. Ngenkathi ungase wazi ama-SNRI njengama-antidepressants, i-milnacipran ithole indawo yayo ekhethekile ekwelapheni izimo zobuhlungu zesikhathi eside ezingathinta kakhulu impilo yakho yansuku zonke.

Yini i-Milnacipran?

I-Milnacipran iyimithi esebenza kabili enyusa amazinga amakhemikhali amabili abalulekile obuchopho: i-serotonin ne-norepinephrine. Lawa ma-neurotransmitters adlala indima ebalulekile endleleni ubuchopho bakho obuqhuba ngayo izimpawu zobuhlungu futhi buphathe imizwa. Ngokungafani neminye imithi ekilasini layo, i-milnacipran inemiphumela elinganiselwe kuwo womabili amakhemikhali, okuyenza isebenze ikakhulukazi ezimweni ezithile zobuhlungu.

Umuthi uza ngesimo samaphilisi futhi uvame ukuthathwa kabili ngosuku. Yenzelwe ukuba ibe yindlela yokwelapha yesikhathi eside kunokulungisa okusheshayo, okusho ukuthi cishe uzodinga ukuyithatha njalo amasonto amaningana ngaphambi kokuzwa izinzuzo zayo eziphelele. Le ndlela enqekelezayo isiza umzimba wakho ukuthi ujwayele umuthi ngenkathi unciphisa imiphumela engaba khona.

Isetshenziselwani i-Milnacipran?

I-Milnacipran ikakhulukazi inikezwa i-fibromyalgia, isimo esingapheli esibonakala ngobuhlungu bemisipha obubanzi nokuba nobumnene. Uma uhlala ne-fibromyalgia, uyazi ukuthi ukuhlala ubuhlungu, ukuqina, nokukhathala kungayithinta kanjani yonke into empilweni yakho. Lo muthi ungasiza ukunciphisa lezi zimpawu futhi uthuthukise izinga lakho jikelele lempilo.

Ngaphandle kwe-fibromyalgia, odokotela ngezinye izikhathi banikeza i-milnacipran ezinye izimo zobuhlungu obungapheli. Lokhu kungabandakanya izinhlobo ezithile zobuhlungu bemizwa, ubuhlungu obungapheli emhlane, noma ezinye izifo zobuhlungu eziqhubekayo ezingaphendulanga kahle kwezinye izindlela zokwelapha. Kodwa-ke, i-fibromyalgia isahlala iyona esetshenziswa kakhulu futhi efundwe kahle.

Kufanelekile ukuqaphela ukuthi ngenkathi i-milnacipran ingasiza kakhulu ekuphatheni ubuhlungu, isebenza kahle kakhulu uma ihlanganiswe nezinye izindlela zokwelapha. Umhlinzeki wakho wezempilo angase ayincomise kanye ne-physical therapy, amasu okulawula ukucindezeleka, noma izinguquko zokuphila ukukunikeza imiphumela engcono kakhulu.

Isebenza Kanjani I-Milnacipran?

I-Milnacipran isebenza ngokuvimba ukuthathwa kabusha kwe-serotonin kanye ne-norepinephrine ebuchosheni bakho. Cabanga ngayo njengokugcina la makhemikhali awusizo etholakala isikhathi eside ezikhaleni eziphakathi kwamaseli emizwa. Lokhu kutholakala okwandisiwe kusiza ukuthuthukisa amasistimu obuchopho emvelo okunciphisa ubuhlungu, okungase kungasebenzi kahle ezimweni zobuhlungu obungapheli.

Lo muthi ubhekwa njengomkhulu ngokulinganisela ekilasini lawo. Inamandla kunezinye izidambisi zokucasuka ezingathengiswa ngaphandle kodokotela kodwa ithambile kunezinye izidambisi zokucasuka ezinamandla zokwelapha. Indlela yokusebenza kabili isho ukuthi ingabhekana nobuhlungu obungokomzimba kanye nezici ezingokomzwelo ezivame ukuhambisana nezimo zobuhlungu obungapheli.

Imiphumela ayenzeki ngokushesha. Abantu abaningi baqala ukuqaphela ukuthuthuka emazingeni abo obuhlungu ngemuva kwamasonto angu-2-4 okusetshenziswa okuqhubekayo. Abanye bangase bathole izinzuzo ngokushesha, kanti abanye bangase badinge amasonto angu-8-12 ukuze bazwe imiphumela ephelele. Lokhu kuqala kancane kuyasiza ngempela, njengoba kuvumela umzimba wakho ukuthi uzivumelanise kancane kancane futhi kunciphisa amathuba okuba nemiphumela emibi.

Kufanele Ngiyithathe Kanjani I-Milnacipran?

Thatha i-milnacipran ngendlela eqondiswe ngayo ngudokotela wakho, ngokuvamile kabili ngosuku ngaphandle kokudla noma ngaphandle kokudla. Abantu abaningi bakuthola kulula ukukhumbula uma beyithatha ngezikhathi ezifanayo nsuku zonke, njengasekuseni nakusihlwa. Ungayithatha ngokudla uma ibangela ukuquleka kwesisu, nakuba lokhu kungadingeki ngaso sonke isikhathi.

Gwinya amaphilisi wonke ngengilazi yamanzi egcwele. Ungawachobozi, uwahlafune, noma uwaqhekeze, ngoba lokhu kungathinta indlela umuthi omuncwa ngayo emzimbeni wakho. Uma unenkinga yokugwinya amaphilisi, khuluma nomkhemisi wakho mayelana namasu angasiza, kodwa ungawashintshi amaphilisi ngokwawo.

Udkt wakho cishe uzoqala ngomthamo ophansi bese uwukhulisa kancane kancane ngesonto lokuqala noma amabili. Le ndlela yokunyuka isiza umzimba wakho ukuba ujwayele umuthi futhi inciphisa imiphumela emibi. Ishejuli ejwayelekile yokuqala ingaqala ngo-12.5 mg kanye ngosuku ngosuku lokuqala, bese kuba ngu-12.5 mg kabili ngosuku izinsuku ezimbili, bese kuba ngu-25 mg kabili ngosuku izinsuku ezine, ngaphambi kokufinyelela umthamo oqondiwe ongu-50 mg kabili ngosuku.

Zama ukuthatha imithamo yakho cishe ngamahora angu-12 ngaphandle ukuze uthole umphumela oqhubekayo kakhulu. Uma uyithatha kabili ngosuku, ekuseni nakusihlwa kusebenza kahle kubantu abaningi. Ungakhathazeki uma ungaqondile amahora angu-12 ngaphandle nsuku zonke - vele zama ukugcina ishejuli ejwayelekile esebenza ngendlela yakho yokuphila.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Milnacipran?

I-Milnacipran ngokuvamile iyindlela yokwelapha yesikhathi eside, okusho ukuthi cishe uzoyithatha izinyanga noma iminyaka. Abantu abaningi abane-fibromyalgia badinga ukwelashwa okuqhubekayo ukuze bagcine ukukhululeka kwabo ezimpawini. Udkt wakho uzosebenza nawe ukunquma ubude obufanele ngokuya ngokuthi usabela kahle kangakanani emuthini nokuthi isimo sakho siqhubeka kanjani.

Abantu abaningi baqhubeka nokuthatha i-milnacipran okungenani izinyanga eziyi-6-12 ngemuva kokuthi izimpawu zabo zithuthuke kakhulu. Lokhu kusiza ukuqinisekisa ukuthi izinzuzo ziyaqhubeka futhi kunciphisa ingozi yokuthi izimpawu zibuye. Abanye abantu bangase badinge ukuyithatha unomphela, kanti abanye bangase bakwazi ukunciphisa kancane kancane umthamo wabo noma bayeke imithi ngaphansi kokuqondiswa kwezokwelapha.

Umhlinzeki wakho wezempilo uzobukeza njalo ukwelashwa kwakho ukuze ahlulele ukuthi kufanele uqhubeke yini, ulungise umthamo, noma ucabange ezinye izinketho. Ungayeki ukuthatha i-milnacipran ngokuzumayo, ngisho noma uzizwa ungcono. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa futhi kungaholela ekubuyeni kobuhlungu bakho. Njalo xoxa nganoma yiziphi izinguquko nodokotela wakho kuqala.

Yiziphi Imiphumela Eceleni ye-Milnacipran?

Njengayo yonke imithi, i-milnacipran ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi imild kuya esimweni esiphakathi nendawo futhi ivame ukuthuthuka njengoba umzimba wakho uzivumela emithini emasontweni ambalwa okuqala.

Imiphumela emibi evame kakhulu ongase uyithole ihlanganisa isicanucanu, ikhanda, isiyezi, nokuqunjelwa. Lokhu kuvamile ukwenzeka ekuqaleni kokwelashwa futhi kuvame ukuba ngaphansi kokukhathaza njengoba uqhubeka nokuthatha imithi.

Nansi imiphumela emibi evame kakhulu okufanele uyazi:

• Isicanucanu nokucasuka kwesisu
• Ikhanda
• Isiyezi noma ukukhathala
• Ukuqunjelwa
• Umlomo owomile
• Ukujuluka okungaphezu kokujwayelekile
• Ubunzima bokulala
• Ukukhathala
• Ukulahlekelwa isifiso sokudla
• Ukushisa okushisayo

Le miphumela emibi ejwayelekile ivame ukulawuleka ngamasu alula njengokuthatha imithi nokudla, ukuhlala unamanzi, nokubekezela njengoba umzimba wakho uzivumela.

Imiphumela emibi engavamile kodwa engathi sína ingenzeka, nakuba ithinta abantu abambalwa. Lokhu kungase kuhlanganise izinguquko ezinkulu ekucindezelweni kwegazi, ukungahambi kahle kwenhliziyo, noma izinguquko ezinzima zemizwa. Nakuba kungavamile, lokhu kudinga ukunakekelwa kwezokwelapha ngokushesha.

Abanye abantu bangase babe nemiphumela emibi engavamile kodwa ebucayi edinga ukunakekelwa kwezempilo ngokushesha:

• Ukungezwani okukhulu komzimba okunezinduna, ukuvuvukala, noma ubunzima bokuphefumula
• Ukwanda okukhulu kwengcindezi yegazi noma izinga lokushaya kwenhliziyo
• Ukuphuma kwegazi okungavamile noma ukuqina
• Ushintsho olukhulu lwemizwa, okuhlanganisa imicabango yokuzilimaza
• Ukushaywa yisithuthwane
• Izinkinga ezinkulu zesibindi (ukuphuzi kwesikhumba noma amehlo)
• I-Angle-closure glaucoma (ubuhlungu emehlweni, izinguquko embonweni)

Uma uhlangabezana nanoma yimiphi yale miphumela emibi, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezimo eziphuthumayo. Khumbula ukuthi udokotela wakho unikeze lo muthi ngoba ukholelwa ukuthi izinzuzo zidlula izingozi esimweni sakho esithile.

Ubani Ongafanele Athathe i-Milnacipran?

I-Milnacipran ayifanele wonke umuntu, futhi izimo ezithile zezokwelapha noma imithi ingenza ingaphephile. Udokotela wakho uzobuyekeza umlando wakho wezokwelapha kanye nemithi yakho yamanje ngaphambi kokuyinikeza ukuze aqinisekise ukuthi iphephile kuwe.

Akufanele uthathe i-milnacipran uma njengamanje uthatha noma usanda kuthatha ama-antidepressants athile abizwa ngokuthi ama-MAOIs (monoamine oxidase inhibitors). Le mithi ingasebenzisana ngendlela eyingozi ne-milnacipran, okungenzeka ibangele isimo esibucayi esibizwa ngokuthi i-serotonin syndrome. Kuzodingeka ulinde okungenani izinsuku eziyi-14 ngemva kokuyeka i-MAOI ngaphambi kokuqala i-milnacipran.

Izimo eziningana zezempilo zidinga ukucatshangelwa okukhethekile ngaphambi kokuqala i-milnacipran:

• Isifo esibi sezinso
• Umfutho wegazi ophezulu ongagadiwe
• Umlando wezinkinga zenhliziyo noma ukushaya kwenhliziyo okungajwayelekile
• Isifo sesibindi
• I-Glaucoma noma ukwanda kwengcindezi yamehlo
• Umlando wokushaywa yisithuthwane
• I-Bipolar disorder noma ezinye izifo zemizwa
• Izifo zokuphuma kwegazi
• Izinkinga zokugcinwa komchamo

Uma unezinye zalezi zimo, udokotela wakho uzohlola ngokucophelela izinzuzo nezingozi ngaphambi kokukuyalela ukuthi usebenzise i-milnacipran. Bangase bakhethe ukukuqapha eduze noma balungise umthamo wakho ngokufanele.

Ukukhulelwa nokuncelisa nako kudinga ukucatshangelwa okukhethekile. Ngenkathi i-milnacipran ingaziwa ngokuqinisekile ukuthi ibangela ingozi ngesikhathi sokukhulelwa, kubalulekile ukuxoxa ngezingozi nezinzuzo nodokotela wakho uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa.

Amagama Omkhiqizo we-Milnacipran

I-Milnacipran itholakala ngaphansi kwegama lomkhiqizo elithi Savella e-United States. Lolu uhlobo oluvame kakhulu ukuyalelwa lomuthi futhi luza ngamandla ahlukahlukene ukuze kuvunyelwe ukulungiswa komthamo okufanele.

Kwamanye amazwe, i-milnacipran ingase itholakale ngaphansi kwamanye amagama omkhiqizo noma amafomula. Uma uhamba noma uthutha, qiniseka ukuthi uxoxa nomkhemisi wakho mayelana nemithi elingana etholakala endaweni yakho entsha.

Izinhlobo ze-Generic ze-milnacipran zingase zitholakale ngokuhamba kwesikhathi, okunganikeza izinketho ezingabizi kakhulu. Njalo thintana nodokotela wakho noma umkhemisi ngaphambi kokushintsha phakathi kwamagama omkhiqizo nezinhlobo ze-generic ukuze uqinisekise ukuthi uthola izinzuzo ezifanayo zokwelapha.

Ezinye Izindlela Zokwelapha nge-Milnacipran

Uma i-milnacipran ingasebenzi kahle kuwe noma ibangela imiphumela engathandeki, imithi eminingi ehlukile ingasiza ekuphatheni i-fibromyalgia nobuhlungu obungapheli. Udokotela wakho angase acabangele ezinye izinhlobo ze-SNRIs, ezinye izinto ezilwa nokuvuvukala, noma ezinye izigaba zemithi ngokuya ngezidingo zakho ezithile.

Ezinye izinhlobo ze-SNRIs njenge-duloxetine (Cymbalta) zisebenza ngendlela efanayo ne-milnacipran kodwa zingase zibe nemiphumela ehlukile. Abanye abantu bayayibekezelela enye kangcono kunenye, ngakho ukushintsha ngaphakathi esigabeni esifanayo ngezinye izikhathi kungasiza.

Imithi elwa nokudlikiza njenge-pregabalin (Lyrica) kanye ne-gabapentin nazo zivame ukusetshenziselwa i-fibromyalgia. Lezi zisebenza ngendlela ehlukile kune-milnacipran ngokuthinta ngqo izimpawu zemizwa, futhi zingaba izinketho ezingcono uma unezinhlobo ezithile zobuhlungu bemizwa.

Izindlela ezingezona imithi nazo zingaba ezinye izindlela eziwusizo noma izithasiselo ohlelweni lwakho lokwelapha. Lokhu kungabandakanya ukwelashwa ngokomzimba, ukwelashwa kokuziphatha ngokuqonda, izindlela zokuphatha ukucindezeleka, izinhlelo zokuzivocavoca ezithambile, noma izindlela eziwusizo ezinjenge-acupuncture noma ukwelashwa ngomzimba.

Ingabe i-Milnacipran Ingcono Kune-Duloxetine?

Kokubili i-milnacipran ne-duloxetine zingama-SNRI asebenzayo asetshenziselwa i-fibromyalgia, kodwa zinezinye izinto ezibalulekile ezingafani. Akukho noyedwa ongcono ngokujwayelekile - ukukhetha okungcono kuncike ezidingweni zakho, umlando wakho wezokwelapha, nokuthi usabela kanjani emithini ngayinye.

I-Milnacipran inemiphumela elinganiselwe emazingeni e-serotonin kanye ne-norepinephrine, kuyilapho i-duloxetine ithinta i-serotonin ngaphezu kwe-norepinephrine. Lomehluko ungase wenze i-milnacipran isebenze kahle ezinhlotsheni ezithile zobuhlungu, kuyilapho i-duloxetine ingase ibe ngcono uma futhi unokucindezeleka okukhulu noma ukukhathazeka.

Amaphrofayili emiphumela emibi afana kodwa awafani. Abanye abantu bayayibekezelela enye ngcono kunenye. I-Duloxetine ingase ibangele ukozela okwengeziwe, kuyilapho i-milnacipran ingase ibangele isicanucanu esiningi ekuqaleni. Udokotela wakho angakusiza ukuthi uhlole lezi zinto ngokusekelwe esimweni sakho esithile.

Izindleko nazo zingaba yinto okufanele icatshangelwe, njengoba ukuhlinzekwa komshuwalense nokutholakala okujwayelekile kungase kuhluke phakathi kwemithi emibili. Xoxa kokubili izici zomtholampilo nezisebenzayo nomhlinzeki wakho wezempilo ukuze unqume ukuthi yini engasebenza kahle kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Milnacipran

Ingabe i-Milnacipran Iphephile Kubantu Abane-High Blood Pressure?

IMilnacipran ingakhuphula umfutho wegazi nesilinganiso senhliziyo kwabanye abantu, ngakho idinga ukuqashwa ngokucophelela uma unomfutho wegazi ophezulu. Udokotela wakho cishe uzohlola umfutho wakho wegazi ngaphambi kokuqala umuthi futhi njalo ngesikhathi sokwelashwa.

Uma unomfutho wegazi ophezulu olawulwa kahle, udokotela wakho angase akwazi ukukuyala i-milnacipran kodwa uzokuqapha eduze. Bangase balungise imithi yakho yomfutho wegazi noma umthamo we-milnacipran njengoba kudingeka. Kodwa-ke, uma umfutho wakho wegazi ungalawuleki, udokotela wakho cishe uzofuna ukuwuzinzisa ngaphambi kokucabangela i-milnacipran.

Kufanele Ngenzeni Uma Ngithatha I-Milnacipran Eningi Ngengozi?

Uma ngengozi uthatha i-milnacipran eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ungalindi ukubona ukuthi ngabe izimpawu ziyavela yini, njengoba ukweqisa kungaba kubi.

Izimpawu ze-milnacipran eningi zingabandakanya isicanucanu esibi, ukuhlanza, isiyezi, ukushaya kwenhliziyo okusheshayo, noma ukudideka. Uma uhlangabezana nanoma yiziphi lezi zimpawu ngemuva kokuthatha imithi eyengeziwe, funa ukunakekelwa kwezempilo okuphuthumayo ngokushesha. Gcina ibhodlela lomuthi nawe ukuze abahlinzeki bezempilo bazi kahle ukuthi uthathe ini nokuthi uthathe malini.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Milnacipran?

Uma uphuthelwa umthamo we-milnacipran, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo. Uma kungaphakathi kwamahora angu-4-6 omthamo wakho olandelayo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi ukukusiza ukuthi uhlale emgqeni neshejuli yakho yemithi.

Ngingayeka Nini Ukuthatha I-Milnacipran?

Kufanele uyeke kuphela ukuthatha i-milnacipran ngaphansi kokuqondisa kukadokotela wakho. Noma ngabe uzizwa ungcono kakhulu, ukuyeka kungazelelwe kungadala izimpawu zokuhoxisa futhi kungaholela ekubuyeni kobuhlungu bakho.

Uma sekuyisikhathi sokuyeka, udokotela wakho uzokwenza isimiso sokunciphisa kancane kancane, anciphise kancane umthamo wakho emasontweni amaningana noma izinyanga. Lokhu kusiza ekuvimbeleni izimpawu zokuhoxisa njengokugajezwa, isicanucanu, ikhanda elibuhlungu, noma izimpawu ezinjenge-flu. Inqubo yokunciphisa inika umzimba wakho isikhathi sokuzivumelanisa namazinga anciphisayo omuthi.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Milnacipran?

Kungcono ukukhawulela noma ukugwema utshwala ngenkathi uthatha i-milnacipran. Utshwala bungandisa ingozi yemiphumela emibi efana nokugajezwa, ukozela, nobunzima bokugxilisa ingqondo. Kungase futhi kwandise ingozi yezinkinga zesibindi.

Uma ukhetha ukuphuza utshwala ngezikhathi ezithile, yenza kanjalo ngokulinganisela futhi unake indlela ozizwa ngayo. Qala ngamanani amancane kunalokho ongawaphuzela ngokujwayelekile ukuze ubone ukuthi umzimba wakho usabela kanjani. Njalo xoxa ngokusebenzisa kwakho utshwala nodokotela wakho, njengoba bengakunikeza iseluleko somuntu siqu esisekelwe esimweni sakho sempilo esithile neminye imithi ongase uyithathe.