Yini i-Pentazocine ne-Naloxone: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Pentazocine ne-naloxone kuyinhlanganisela yomuthi wokwelapha ubuhlungu osiza ekuphatheni ubuhlungu obumaphakathi nendawo obunzima lapho ezinye izindlela zokwelapha zingasebenzi kahle. Lo muthi oqoshwe ngudokotela uqukethe izithako ezimbili ezisebenzayo ezisebenza ndawonye - i-pentazocine inikeza ukukhululeka kobuhlungu, kuyilapho i-naloxone isiza ekuvikeleni ukusetshenziswa kabi komuthi.

Uma ubhekene nobuhlungu obuqhubekayo obuthinta impilo yakho yansuku zonke, udokotela wakho angase acabange lo muthi njengengxenye yohlelo lwakho lokwelapha. Kubalulekile ukuqonda ukuthi lo muthi usebenza kanjani nokuthi yini ongayilindela lapho uwuthatha.

Yini i-Pentazocine ne-Naloxone?

I-Pentazocine ne-naloxone ngumuthi oqoshwe ngudokotela ohlanganisa imithi emibili ehlukene ukudala isixazululo esisebenzayo sokuphatha ubuhlungu. I-Pentazocine ingeyeqembu lemithi ebizwa ngokuthi ama-opioid analgesics, asebenza ngokushintsha indlela ubuchopho bakho obuqonda ngayo izimpawu zobuhlungu.

Ingxenye ye-naloxone isebenza njengesici sokuphepha esakhelwe emuthini. Uma uthatha lo muthi ngomlomo njengoba uqoshiwe, i-naloxone ihlala ingasebenzi futhi ayiphazamisi ukukhululeka kobuhlungu. Kodwa-ke, uma othile ezama ukusebenzisa kabi umuthi ngokuwujova, i-naloxone iyasebenza futhi ivimbele imiphumela.

Le ndlela yokuhlanganisa isiza abahlinzeki bezempilo ukuthi banikeze ukukhululeka kobuhlungu okusebenzayo ngenkathi kunciphisa ingozi yokusetshenziswa kabi komuthi. Lo muthi uvame ukuqoshwa lapho ezinye izinketho zokuphatha ubuhlungu zingazange zinikeze ukukhululeka okwanele.

Isetshenziselwani i-Pentazocine ne-Naloxone?

Udokotela wakho angase aqoshe i-pentazocine ne-naloxone uma ubhekene nobuhlungu obumaphakathi nendawo obunzima obungazange busabele kahle eminye imithi yokwelapha ubuhlungu. Lo muthi ulusizo ikakhulukazi ezimweni zobuhlungu obungapheli obudinga ukuphathwa okuqhubekayo.

Izimo ezivamile lapho lo muthi kungenzeka ukuthi ubhalwe khona zihlanganisa ubuhlungu obuqhubekayo emhlane, ubuhlungu emalungeni obangelwa yi-arthritis, ubuhlungu ngemva kokuhlinzwa, noma ezinye izimo zobuhlungu besikhathi eside. Umhlinzeki wakho wezempilo uzohlola ngokucophelela isimo sakho esithile ukuze anqume ukuthi lo muthi ukufanele yini.

Umuthi usebenza kahle kakhulu njengengxenye yohlelo olubanzi lokuphatha ubuhlungu. Udokotela wakho angase futhi ancome ukwelashwa ngokomzimba, izinguquko zokuphila, noma ezinye izindlela zokwelapha kanye nalo muthi ukukusiza ukuthi uzuze ukukhululeka kobuhlungu okungcono kakhulu.

Isebenza Kanjani I-Pentazocine ne-Naloxone?

I-Pentazocine isebenza ngokunamathela kuma-receptors athile ebuchosheni bakho nasemgogodleni okuthiwa ama-opioid receptors. Uma inamathisela kula ma-receptors, iguqula indlela uhlelo lwakho lwezinzwa olucubungula ngayo izimpawu zobuhlungu, okusiza ukunciphisa ukuqina kobuhlungu obuzwayo.

Lo muthi ubhekwa njenge-partial opioid agonist, okusho ukuthi unikeza ukukhululeka kobuhlungu okusebenzayo ngenkathi unengozi ephansi yokucindezeleka kokuphefumula uma kuqhathaniswa neminye imithi ye-opioid. Isenzo se-partial agonist sidala lokho okuvame ukubizwa ngokuthi

Uma usebenzisa lo muthi njalo, zama ukuhlukanisa imithamo yakho ngokulinganayo usuku lonke. Lokhu kusiza ukugcina amazinga aqhubekayo omuthi emzimbeni wakho ukuze uthole ukukhululeka kobuhlungu okuqhubekayo.

Gcina umbhalo wokuthi umuthi usebenza kahle kangakanani ubuhlungu bakho. Uma uthola ukuthi umthamo wakho ovamile awunikezi ukukhululeka okwanele, khuluma nodokotela wakho esikhundleni sokwandisa umthamo ngokwakho.

Kufanele ngiwuthatha isikhathi esingakanani i-Pentazocine ne-Naloxone?

Ubude besikhathi ozothatha ngaso lo muthi busekelwe esimweni sakho esithile nokuthi umzimba wakho usabela kanjani ekwelashweni. Abanye abantu bangase bawudinge amasonto ambalwa ngemva kokuhlinzwa, kanti abanye abanezimo ezingapheli bangase bawuthathe isikhathi eside.

Udokotela wakho uzobuyekeza njalo amazinga obuhlungu bakho nokusabela okuphelele emuthini. Bazohlola ukuthi ngabe izinzuzo zisaqhubeka yini ukwedlula noma yiziphi izingozi ezingaba khona futhi balungise uhlelo lwakho lokwelashwa ngokufanele.

Uma ubuthathe lo muthi amasonto amaningi noma isikhathi eside, ungayeki ukuwuthatha kungazelelwe. Udokotela wakho cishe uzoncoma ukunciphisa kancane umthamo wakho ngokuhamba kwesikhathi ukuvimbela izimpawu zokuhoxiswa futhi uqinisekise ukunethezeka kwakho ngesikhathi sokushintsha.

Yiziphi Imiphumela Eceleni ye-Pentazocine ne-Naloxone?

Njengayo yonke imithi, i-pentazocine ne-naloxone ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi ulawule noma yimiphi imiphumela eyenzekayo futhi wazi ukuthi ungaxhumana nini nomhlinzeki wakho wezempilo.

Imiphumela emibi evame kakhulu ngokuvamile imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi:

• Isicanucanu noma isisu esibuhlungu
• Isiyezi noma ukuzwa ukukhanya ekhanda
• Ukozela noma ukuzizwa ukhathele
• Ukuqunjelwa
• Ikhanda
• Umlomo owomile

Le miphumela evamile ivame ukungabonakali ngemva kokuthi ubuthathe umuthi izinsuku ezimbalwa. Ukuphuza amanzi amaningi nokudla ukudla okunothile nge-fiber kungasiza ngokuqunjelwa.

Abanye abantu bangase babe nemiphumela emibi kakhulu edinga ukunakekelwa kwezempilo ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukwazi ukuthi yini okufanele uyibheke:

• Ubunzima bokuphefumula noma ukuphefumula kancane
• Ukudideka okukhulu noma ukulahlekelwa yisikhundla
• Ubuhlungu besifuba noma ukushaya kwenhliziyo okungajwayelekile
• Ukuphendula okukhulu komzimba ngokuqubuka, ukuvuvukala, noma ubunzima bokuphefumula
• Ukucabanga okungamanga noma ukubona izinto ezingekho
• Ukozela okukhulu okwenza kube nzima ukuvuka

Uma uhlangabezana nanoma yimiphi yale miphumela emibi, funa usizo lwezempilo ngokushesha. Ukuphepha kwakho yikho konke okubalulekile, futhi abahlinzeki bezempilo baqeqeshwe ukusiza ukuphatha lezi zimo.

Ubani Ongafanele Athathwe I-Pentazocine ne-Naloxone?

Abantu abathile kufanele bagweme lo muthi ngenxa yezingozi ezengeziwe noma izinkinga ezingaba khona. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela lo muthi ukuze aqinisekise ukuthi uphephile kuwe.

Akufanele uthathe lo muthi uma wazi ukuthi unokungezwani komzimba ne-pentazocine, naloxone, noma ezinye izinto zomuthi. Izimpawu zokuphendula komzimba zingabandakanya ukuqubuka, ukuluma, ukuvuvukala, noma ubunzima bokuphefumula.

Abantu abanezinkinga ezinkulu zokuphefumula, njenge-asthma enkulu noma ubunzima bokuphefumula, ngokuvamile kufanele bagweme lo muthi. Umuthi unganciphisa ukuphefumula, okungaba yingozi kumuntu osevele enobunzima bokuphefumula.

Lo muthi kungenzeka awufaneleki uma unezimo ezithile zenhliziyo, isifo sesibindi esibi, noma umlando wokulimala ekhanda. Udokotela wakho uzohlola lezi zici futhi anqume ukuthi izinzuzo zidlula izingozi esimweni sakho esithile.

Uma ukhulelwe noma uncelisa, xoxa ngezingozi nezinzuzo nomhlinzeki wakho wezempilo. Umuthi ungangena enganeni yakho futhi ungase ubangele izimpawu zokuhoxiswa ezinganeni ezisanda kuzalwa uma zisetshenziswa njalo ngesikhathi sokukhulelwa.

Amagama Omkhiqizo we-Pentazocine ne-Naloxone

Igama elivamile lomkhiqizo we-pentazocine kanye ne-naloxone ngumkhiqizo i-Talwin NX. Leli gama lomkhiqizo lisiza ukuhlukanisa kulawa ma-formulations e-pentazocine angenawo i-naloxone.

Amanye amakhemisi angase abe nezinhlobo ze-generic zalo muthi, oqukethe izithako ezifanayo ezisebenzayo kodwa zingase zibukeke zihluke kunenguqulo yegama lomkhiqizo. Imithi ye-Generic ihlolwa ngendlela efanayo eqinile yokuphepha nokusebenza njengemithi yegama lomkhiqizo.

Njalo hlola nomkhemisi wakho uma ubona ukuthi umuthi wakho ubukeka uhlukile kulokho oqhelelene nakho. Bangaqinisekisa ukuthi ngabe uthole umuthi ofanele futhi baphendule noma yimiphi imibuzo mayelana nezinhlobo ze-generic vs. brand name.

Ezinye izindlela ze-Pentazocine kanye ne-Naloxone

Uma i-pentazocine kanye ne-naloxone kungafaneleki kahle ezidingweni zakho zokuphatha ubuhlungu, izindlela zokwelapha eziningana ezingezinye zingase zicatshangelwe. Udokotela wakho uzosebenza nawe ukuthola inketho efanele kakhulu ngokuya ngesimo sakho esithile kanye nomlando wezokwelapha.

Eminye imithi yokwelapha ubuhlungu kadokotela ihlanganisa izinhlobo ezahlukene zama-opioids, njenge-tramadol, i-codeine, noma imithi esekwe ku-morphine. Ngamunye unohlu lwawo lwezinzuzo nemiphumela engaba khona, futhi udokotela wakho uzocabangela lezi zinto lapho enza izincomo.

Ezinye izindlela ezingezona i-opioid zingabandakanya imithi eqeda ukuvuvukala enamandla, ama-antidepressants athile asiza ngobuhlungu, noma imithi elwa nokuhlaselwa engasebenza ngobuhlungu bemizwa. Lezi zinketho zisebenza ngendlela ehlukile kuma-opioids kodwa zingahlinzeka ngokuqeda ubuhlungu obukhulu kubantu abaningi.

Udokotela wakho angase futhi ancome ukuhlanganisa imithi nokunye ukwelashwa okufana ne-physical therapy, i-cognitive behavioral therapy, noma izindlela zokwengeza ezifana ne-acupuncture noma i-massage therapy.

Ingabe i-Pentazocine kanye ne-Naloxone ingcono kunezinye izindlela zokwelapha ubuhlungu?

Noma i-pentazocine ne-naloxone ingcono kunezinye izidakamizwa zokwelapha ubuhlungu kuncike esimweni sakho somuntu ngamunye, uhlobo lobuhlungu obuzwayo, nokuthi umzimba wakho usabela kanjani ekwelashweni okuhlukahlukene. Akukho umuthi owodwa wokwelapha ubuhlungu osebenza kahle kuwo wonke umuntu.

Le nhlanganisela yemithi inikeza ezinye izinzuzo eziyingqayizivele, ikakhulukazi isici esakhelwe ngaphakathi sokuvimbela ukusetshenziswa kabi esivela engxenyeni ye-naloxone. Lokhu kuyenza ibe yinketho ebalulekile kubantu abadinga ukukhululeka kobuhlungu obusebenzayo kodwa abakhathazekile ngokusebenzisa kabi imithi.

Uma kuqhathaniswa neminye imithi ye-opioid, i-pentazocine ingase ibe nengozi ephansi yokucindezeleka kokuphefumula ngenxa yezakhiwo zayo ze-partial agonist. Kodwa-ke, lokhu akusho ukuthi iphephile ngokuzenzakalelayo kuwo wonke umuntu - udokotela wakho uzocabangela isithombe sakho esiphelele sezokwelapha.

Umuthi ongcono kakhulu wokwelapha ubuhlungu kuwe ngumuthi olawula ngempumelelo ubuhlungu bakho ngenkathi ubangela imiphumela emincane futhi ofanelana kahle nendlela yakho yokuphila nezinye izimo zempilo. Umhlinzeki wakho wezempilo ungumuntu ongcono kakhulu ongakusiza ukuthi wenze lesi sinqumo.

Imibuzo Evame Ukubuzwa Mayelana ne-Pentazocine ne-Naloxone

Ingabe i-Pentazocine ne-Naloxone Iphephile Kubantu Abanezifo Zenhliziyo?

Abantu abanezifo zenhliziyo badinga ukucatshangelwa okukhethekile lapho bethatha i-pentazocine ne-naloxone. Umuthi ungathinta izinga lokushaya kwenhliziyo nomfutho wegazi, okungase kukhathaze umuntu onezinkinga zenhliziyo ezikhona.

Udokotela wakho wenhliziyo nodokotela wakho oyinhloko kufanele basebenzisane ukuze bahlole ukuthi lo muthi ulungele yini isimo sakho senhliziyo esithile. Bazocabangela izinto ezinjengobunzima besifo sakho senhliziyo, eminye imithi oyithathayo, nesimo sakho sempilo esiphelele.

Uma uthatha lo muthi ngesifo senhliziyo, cishe uzodinga ukuqapha kaningi ukuze uqinisekise ukuthi inhliziyo yakho ihlala izinzile. Ungalokothi uqale noma uyeke lo muthi ngaphandle kokuxoxa ngakho nodokotela wakho obhalayo nodokotela wakho wenhliziyo.

Kumele Ngenzeni Uma Ngithathe I-Pentazocine ne-Naloxone Engaphezu Kwemithi?

Uma uthathe ngaphezu komthamo okubhalelwe wona, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma uzizwa kahle. Ukuthatha umuthi omningi kakhulu kungaba yingozi futhi kungadinga ukwelashwa kwezokwelapha.

Izimpawu zokweqisa zingabandakanya ukozela okukhulu, ukuphefumula okuhamba kancane noma okunzima, ukudideka okukhulu, noma ukulahlekelwa ukwazi. Uma wena noma omunye umuntu enezimpawu ezinjalo, shayela izinsiza eziphuthumayo ngokushesha.

Gcina ibhodlela lomuthi unawo uma ufuna usizo lwezokwelapha, njengoba lolu lwazi luzosiza abahlinzeki bezempilo ukuthi banqume indlela engcono kakhulu yokwelapha. Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo ukuthi wenze kanjalo ngumhlinzeki wezempilo.

Kumele Ngenzeni Uma Ngiphuthelwa Umthamo We-Pentazocine ne-Naloxone?

Uma uthatha lo muthi ngeshejuli ejwayelekile futhi uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe. Lokhu kungakhuphula ingozi yakho yemiphumela emibi kanye nezinkinga eziyingozi.

Uma uthatha umuthi kuphela uma udinga ukwelashwa kobuhlungu, vele uthathe umthamo wakho olandelayo lapho uzwa ubuhlungu obudinga ukwelashwa. Gcina umkhondo wokuthi ngubani ngesikhathi sokugcina owathatha umuthi ukuze uqinisekise ukuthi awuthathi imithamo eseduze kakhulu.

Ngingayeka Nini Ukuthatha I-Pentazocine ne-Naloxone?

Isinqumo sokuyeka ukuthatha lo muthi kufanele senziwe ngaso sonke isikhathi ngokubonisana nomhlinzeki wakho wezempilo. Bazohlola amazinga akho obuhlungu, impilo yakho yonke, nokuthi usuthatha isikhathi esingakanani umuthi ukuze banqume indlela engcono kakhulu.

Uma ubelokhu usebenzisa umuthi njalo isikhathi esingaphezu kwamasonto ambalwa, udokotela wakho cishe uzoncoma ukunciphisa umthamo wakho kancane kancane kunokumisa kungazelelwe. Lokhu kusiza ekuvikeleni izimpawu zokuhoxisa futhi kuqinisekisa ukunethezeka kwakho ngesikhathi sokuguquka.

Udokotela wakho angase asikisele ukumisa umuthi uma ubuhlungu bakho buye ngcono kakhulu, uma uhlangabezana nemiphumela engathandeki, noma uma befuna ukuzama enye indlela yokwelapha. Bazosebenza nawe ukuthuthukisa uhlelo oluphephile lokuyeka umuthi.

Ngingashayela Ngenkathi Ngithatha i-Pentazocine ne-Naloxone?

Lo muthi ungabangela ukozela, isiyezi, nokucabanga okungahambisani kahle, ikakhulukazi uma uqala ukuwuthatha noma uma umthamo wakho ukhuphuka. Le miphumela ingenza ukushayela kube yingozi kuwe nakwabanye emgwaqeni.

Gwema ukushayela noma ukusebenzisa imishini kuze kube yilapho wazi ukuthi lo muthi ukuthinta kanjani. Abanye abantu bangase bakwazi ukushayela ngokuphepha ngemva kokuthatha umuthi isikhashana futhi umzimba wabo usuzivumelanise, kanti abanye bangase badinge ukugwema ukushayela ngokuphelele ngenkathi besalelashwa ngalo muthi.

Xoxa nodokotela wakho ngesimo sakho esithile nokuthi kungaba nini kuphephile ukuthi uqhubeke nokushayela. Bangakunikeza isiqondiso esiqondene nawe ngokusekelwe ekuphenduleni kwakho emuthini kanye nemisebenzi yakho yansuku zonke.