Yini i-Perindopril: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Perindopril iyimithi kadokotela esiza ukwehlisa umfutho wegazi nokuvikela inhliziyo yakho. Ingaphansi kweqembu lemithi ebizwa ngokuthi ama-ACE inhibitors, asebenza ngokukhulula imithambo yakho yegazi ukuze igazi ligeleze kalula. Le ndlela enobumnene kodwa esebenzayo iyenza ibe yindlela ethenjwayo yokuphatha umfutho wegazi ophezulu nezifo zenhliziyo.

Yini i-Perindopril?

I-Perindopril iyimithi ye-ACE inhibitor udokotela wakho ayinikezayo ukusiza ukuphatha umfutho wegazi nempilo yenhliziyo. I-ACE imele i-angiotensin-converting enzyme, okuyinto emzimbeni wakho engenza imithambo yegazi iqine.

Cabanga nge-perindopril njengomsizi onobumnene otshela imithambo yakho yegazi ukuthi iphumule futhi yande. Uma imithambo yakho yegazi iphumule kakhulu, inhliziyo yakho akudingeki isebenze kanzima ukuze ipompe igazi emzimbeni wakho wonke. Lokhu kwenza kube lula ukuthi inhliziyo yakho yenze umsebenzi wayo futhi kusiza ukugcina umfutho wegazi lakho ebangeni elinempilo.

Umuthi uza ngesimo samaphilisi futhi uthathwa ngomlomo, ngokuvamile kanye ngosuku. Isetshenziswe ngokuphepha yizigidi zabantu emhlabeni wonke iminyaka eminingi, okuyenza ibe yindlela yokwelapha esungulwe kahle ethenjwa odokotela.

Isetshenziselwani i-Perindopril?

I-Perindopril ikakhulukazi inikezwa ukwelapha umfutho wegazi ophezulu, owaziwa nangokuthi i-hypertension. Umfutho wegazi ophezulu uthinta abantu abadala abaningi futhi ngokuvamile awunawo amasignali, yingakho ngezinye izikhathi ubizwa ngokuthi “umbulali othule.”

Udokotela wakho angase futhi anikeze i-perindopril uma unenhliziyo ehlulekayo, isimo lapho inhliziyo yakho ilwela ukumpompa igazi ngempumelelo. Umuthi usiza ukunciphisa umsebenzi wenhliziyo yakho, okwenza kube lula ukuthi leli lungu elibalulekile lisebenze kahle.

Ngaphezu kwalokho, i-perindopril ingasetshenziswa ukusiza ekuvikeleni ukuhlaselwa yinhliziyo nokushaywa unhlangothi kubantu abanezifo zemithambo yenhliziyo noma ezinye izimo zenhliziyo. Ilusizo ikakhulukazi kubantu abanesifo sikashukela, njengoba ingavikela izinso ekulimaleni okungenzeka kubangelwe umfutho wegazi ophezulu ngokuhamba kwesikhathi.

Abanye odokotela banikeza i-perindopril ngemuva kokuhlaselwa yinhliziyo ukusiza ukuvikela imisipha yenhliziyo nokuthuthukisa imiphumela yesikhathi eside. Umuthi usekela impilo yonke yohlelo lwakho lwe-cardiovascular futhi usiza ekuvikeleni izinkinga zesikhathi esizayo.

Isebenza Kanjani I-Perindopril?

I-Perindopril isebenza ngokuvimba i-enzyme emzimbeni wakho ebizwa nge-ACE, evame ukusiza ekukhiqizeni into eyenza imithambo yegazi inciphe. Ngokuvimba le enzyme, i-perindopril ivimbela imithambo yakho yegazi ukuthi ingaqini ngokungadingekile.

Lapho imithambo yakho yegazi ihlala iphumule futhi ivulekile, igazi lingahamba ngokushelela emzimbeni wakho wonke. Lokhu kunciphisa ingcindezi odongeni lwemithambo yakho, okuyilokho esikulinganisela njengomfutho wegazi. Cabanga ngakho njengokwandisa ipayipi lengadi - inani elifanayo lamanzi lihamba kalula lapho ipayipi libanzi.

I-Perindopril ithathwa njenge-inhibitor ye-ACE enamandla aphakathi nendawo, okusho ukuthi iyasebenza kodwa ivame ukubekezelelwa kahle ngabantu abaningi. Iqala ukusebenza kungakapheli amahora ambalwa ngemuva kokuyithatha, kodwa ungase ungazizwa izinzuzo ezigcwele amasonto ambalwa njengoba umzimba wakho ujwayela umuthi.

Umuthi futhi usiza izinso zakho ukususa usawoti namanzi amaningi emzimbeni wakho, okusiza ngokuqhubekayo ukunciphisa umfutho wegazi. Lesi senzo esiphindwe kabili senza i-perindopril isebenze ikakhulukazi ekuphatheni impilo ye-cardiovascular.

Kufanele Ngiyithathe Kanjani I-Perindopril?

Thatha i-perindopril ngendlela udokotela wakho ayala ngayo, ngokuvamile kanye ngosuku ngesikhathi esifanayo nsuku zonke. Abantu abaningi bakuthola kulula ukuyithatha ekuseni ngesidlo sasekuseni, njengoba lokhu kusiza ukusungula umkhuba futhi kunciphisa ithuba lokukhohlwa umthamo.

Ungathatha i-perindopril ngaphandle kokudla noma ngemva kokudla, nakuba ukuyithatha ngokudla okulula kungasiza ekuvimbeleni noma yikuphi ukuphathwa yisisu. Gwinya ithebhulethi yonke ngamanzi - ungayichobozi, ungayihlafuni, noma ungayiqhekezi ithebhulethi ngoba lokhu kungathinta ukuthi imithi isebenza kanjani.

Uma uqala nje ukuthatha i-perindopril, udokotela wakho cishe uzoqala ngomthamo ophansi bese ewukhulisa kancane kancane emahoreni ambalwa. Le ndlela eqaphelayo isiza umzimba wakho ukuthi ujwayele imithi futhi inciphisa imiphumela engemihle engaba khona.

Zama ukuthatha umthamo wakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo emithi emzimbeni wakho. Ukusetha isikhumbuzi sefoni noma ukugcina ibhodlela lakho lemithi endaweni ebonakalayo kungakusiza ukuthi ukhumbule ukuyithatha njalo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Perindopril?

I-Perindopril ngokuvamile iyimithi yesikhathi eside okuzodingeka uyithathe izinyanga noma iminyaka ukuze ugcine izinzuzo zayo. Umfutho wegazi ophezulu nezimo zenhliziyo ziyizimo ezingapheli ezidinga ukuphathwa okuqhubekayo kunokwelashwa kwesikhashana.

Abantu abaningi baqhubeka nokuthatha i-perindopril unomphela, njengoba ukuyeka imithi ngokuvamile kubangela ukuthi umfutho wegazi ubuyele emazingeni angaphambilini ezinsukwini noma emasontweni. Udokotela wakho uzoqapha ukusabela kwakho emithini futhi angase alungise umthamo wakho ngokuhamba kwesikhathi ngokusekelwe ekufundweni komfutho wegazi lakho kanye nempilo yakho yonke.

Abanye abantu bangase bakwazi ukunciphisa umthamo wabo noma bayeke imithi uma benza izinguquko ezinkulu zokuphila njengokulahlekelwa isisindo, ukuzivocavoca njalo, nokulandela ukudla okunempilo enhliziyo. Nokho, lesi sinqumo kufanele senziwe ngaso sonke isikhathi ngesiqondiso sikadokotela wakho.

Ukuvakashelwa njalo nodokotela wakho kubalulekile ukuqinisekisa ukuthi imithi iyaqhubeka nokusebenza ngempumelelo nokubheka noma yimiphi imiphumela engemihle engaba khona. Ungayeki ukuthatha i-perindopril ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala, ngoba lokhu kungabangela ukuthi umfutho wegazi lakho ukhuphuke ngendlela eyingozi.

Yiziphi Imiphumela Engemihle Ye-Perindopril?

Njengazo zonke izidakamizwa, i-perindopril ingabangela imiphumela emibi, nakuba abantu abaningi bengabi nazinkinga eziningi. Imiphumela emibi evame kakhulu ngokuvamile ithambile futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nawa amanye emiphumela emibi ebikwa njalo ongase uyithole:

• Ukhwehlela olomile olungapheli
• Isiyezi noma ukukhathala, ikakhulukazi uma usukuma
• Ikhanda
• Ukukhathala noma ukuzizwa ukhathele ngokungavamile
• Isicanucanu noma isisu esibuhlungu
• Amajaqamba emisipha noma ubuthakathaka

Ukhwehlela olomile yiwona mthelela ohlukile kakhulu wama-ACE inhibitors afana ne-perindopril. Ithinta cishe u-10-15% wabantu abathatha umuthi futhi ngokuvamile ithuthuka emasontweni ambalwa okuqala okwelashwa.

Imiphumela emibi engavamile kodwa ebucayi idinga ukunakekelwa kwezempilo ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukwazi:

• Ukungezwani okukhulu komzimba nokuvuvukala kobuso, izindebe, ulimi, noma umphimbo
• Isiyezi esikhulu noma ukuquleka
• Ukushaya kwenhliziyo okungajwayelekile
• Ubuhlungu obukhulu besisu
• Ukuphuzi kwesikhumba noma amehlo
• Ukuphuma kwegazi okungavamile noma ukulimala

Uma uhlangabezana nanoma yimiphi yale miphumela emibi, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezempilo eziphuthumayo. Lezi zimpendulo azivamile kodwa zingaba zimbi uma zingelashwa ngokushesha.

Ubani Ongafanele Athole I-Perindopril?

Abantu abathile akufanele bathathe i-perindopril ngenxa yengozi eyengeziwe yezinkinga ezinkulu. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela lo muthi ukuze aqinisekise ukuthi uphephile kuwe.

Akufanele uthathe i-perindopril uma wake waba nokungezwani komzimba okukhulu kuma-ACE inhibitors. Lolu hlobo lokusabela, olubizwa ngokuthi i-angioedema, lungabangela ukuvuvukala okuyingozi kobuso, izindebe, ulimi, noma umphimbo futhi lungasongela impilo.

Abantu abanezimo ezithile zezinso kungenzeka bangakwazi ukuthatha i-perindopril ngokuphepha. Uma unesifo esibi sezinso noma use-dialysis, udokotela wakho uzodinga ukuhlola ngokucophelela ukuthi lo muthi ukufanele yini.

Abesifazane abakhulelwe akufanele bathathe i-perindopril, ikakhulukazi ngesikhathi sesibili nesesithathu sokukhulelwa, ngoba kungalimaza ingane esakhula. Uma uhlela ukukhulelwa noma uthola ukuthi ukhulelwe ngenkathi uthatha i-perindopril, xhumana nodokotela wakho ngokushesha ukuze nixoxe ngezindlela zokwelapha ezingezinye.

Abantu abanomfutho wegazi ophansi kakhulu noma labo abomile kungenzeka bangabi ngabantu abafanelekayo i-perindopril, njengoba umuthi unganciphisa umfutho wegazi ngaphezulu. Udokotela wakho uzohlola umfutho wegazi lakho kanye nesimo sempilo yakho yonke ngaphambi kokuqala ukwelashwa.

Amagama Omkhiqizo we-Perindopril

I-Perindopril itholakala ngaphansi kwamagama amaningi omkhiqizo, okujwayelekile kakhulu yi-Aceon e-United States. Amanye amagama omkhiqizo afaka i-Coversyl, esetshenziswa kakhulu emazweni amaningi emhlabeni jikelele.

Ifomu elivamile le-perindopril nalo liyatholakala futhi lisebenza ngendlela efanayo nenguqulo yegama lomkhiqizo. Imithi ejwayelekile iqukethe isithako esifanayo esisebenzayo futhi ihlangabezana namazinga afanayo ekhwalithi njengemithi yegama lomkhiqizo, ngokuvamile ngentengo ephansi.

Ikhemisi lakho lingase lithathe indawo yenguqulo ejwayelekile yegama lomkhiqizo ngaphandle uma udokotela wakho ecela ngokuqondile umuthi wegama lomkhiqizo. Zombili izinhlobo zisebenza ngendlela efanayo, ngakho-ke ungaqiniseka ukuthi usebenzisa noma iyiphi inguqulo udokotela wakho ayincomayo.

Uma unezinkinga ngokushintsha phakathi kwezinhlobo zomkhiqizo nezivamile, xoxa ngalokhu nodokotela wakho noma usokhemisi. Bangakusiza ukuthi uqonde izinketho futhi baqinisekise ukuthi uthola umuthi ofanele kakhulu izidingo zakho.

Ezinye izindlela ze-Perindopril

Uma i-perindopril ingakulungele noma ibangela imiphumela emibi, imithi eminingi ehlukile ingasiza ekuphatheni umfutho wegazi nezifo zenhliziyo. Udokotela wakho angakusiza ukuthi uthole inketho engcono kakhulu ngokusekelwe ezidingweni zakho zempilo.

Ezinye izithiyo ze-ACE ezifana ne-lisinopril, enalapril, noma i-ramipril zisebenza ngendlela efanayo ne-perindopril futhi zingase zibekezelelwe kangcono ngabanye abantu. Le mithi inendlela efanayo yokusebenza kodwa ingase ibe nemiphumela emibi ehlukile.

Ama-ARBs (ama-angiotensin receptor blockers) afana ne-losartan noma i-valsartan anikeza enye inketho kubantu abangakwazi ukubekezelela izithiyo ze-ACE. Ama-ARBs asebenza ngendlela efanayo nezithiyo ze-ACE kodwa maningi amathuba okuthi abangele ukukhwehlela okomile okuqhubekayo abanye abantu ababa nakho nge-perindopril.

Kwabanye abantu, ama-calcium channel blockers afana ne-amlodipine noma ama-beta-blockers afana ne-metoprolol angase abe ezinye izindlela ezifanele. Le mithi isebenza ngezindlela ezihlukene zokwehlisa umfutho wegazi nokuvikela inhliziyo.

Udokotela wakho uzocabangela impilo yakho yonke, eminye imithi oyithathayo, nezidingo zakho ezithile zenhliziyo nemithambo yegazi lapho encoma ezinye izindlela. Ungalokothi ushintshe imithi ngokwakho - njalo sebenzisana nomhlinzeki wakho wezempilo ukuze uthole uhlelo olungcono kakhulu lokwelapha.

Ingabe i-Perindopril Ingcono Kune-Lisinopril?

Kokubili i-perindopril ne-lisinopril ziyizithiyo ze-ACE ezisebenzayo ezisebenza kahle ekuphatheni umfutho wegazi nezifo zenhliziyo. Akukho mithi enye engcono kunenye - ukukhetha okungcono kakhulu kuncike ezidingweni zakho zempilo kanye nendlela ozosabela ngayo emithini ngayinye.

I-Perindopril ivame ukuba nesikhathi eside sokusebenza, okusho ukuthi ingase inikeze ukulawulwa komfutho wegazi okuqhubekayo usuku lonke. Ezinye izifundo zikhomba ukuthi ingase ibe ngcono kancane ekuvikeleni inhliziyo nezinso, nakuba yomibili imithi inikeza izinzuzo ezinkulu zenhliziyo nemithambo yegazi.

I-Lisinopril isetshenziswe iminyaka eminingi futhi inocwaningo oluningi olusekela ukusebenza kwayo nokuphepha kwayo. Ivame ukukhethwa njengokwelashwa kokuqala ngoba ifundwe kahle futhi ivame ukubekezelelwa abantu abaningi.

Amaphrofayili emiphumela emibi yomibili imithi iyafana, nakuba abantu ngabanye bengase bakwazi ukubekezelela enye kangcono kunenye. Abanye abantu bathola ukuthi i-perindopril ibangela ukukhwehlela okuncane, kanti abanye benza kangcono nge-lisinopril.

Udokotela wakho uzocabangela izinto ezifana nokusebenza kwezinso zakho, ezinye izimo zempilo, nokuthi usabele kanjani emithini yangaphambilini lapho ekhetha phakathi kwalezi zinketho. Umuthi “ongcono” ngumuthi olawula ngempumelelo umfutho wegazi lakho ngemiphumela emibi embalwa kuwe uqobo.

Imibuzo Evame Ukubuzwa Mayelana ne-Perindopril

Ingabe i-Perindopril iphephile kubantu abanesifo sikashukela?

Yebo, i-perindopril ngokuvamile iphephile futhi ivame ukuzuzisa abantu abanesifo sikashukela. Eqinisweni, ama-ACE inhibitors afana ne-perindopril avame ukunconywa ezigulini ezinomdlavuza ngoba angasiza ukuvikela izinso ekulimaleni okubangelwa amazinga kashukela aphezulu egazini.

Abantu abanesifo sikashukela basengozini enkulu yezinkinga zenhliziyo nezinso, futhi i-perindopril ingasiza ukunciphisa lezi zingozi. Umuthi ngokuvamile awuthinti ngokuqondile amazinga kashukela egazini, ngakho ngeke uphazamise ukuphathwa kwesifo sakho sikashukela.

Nokho, kufanele uqaphele umfutho wegazi lakho nokusebenza kwezinso uma unesifo sikashukela. Udokotela wakho cishe uzo-oda ukuhlolwa kwegazi njalo ukuze aqinisekise ukuthi izinso zakho zisebenza kahle ngenkathi uthatha i-perindopril.

Ngingenzani uma ngiphuthelwa ngithatha i-Perindopril eningi kakhulu?

Uma ngengozi uthatha i-perindopril eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kakhulu kungabangela umfutho wegazi ophansi oyingozi, okungakwenza uzizwe unesiyezi, ubuthakathaka, noma kukubangele ukuba uquleke.

Ungalindi ukubona ukuthi uzizwa ulungile yini - funa usizo lwezokwelapha ngokushesha, ikakhulukazi uma uthathe okuningi kakhulu kunomthamo wakho ovamile. Abahlinzeki bezempilo bangakwazi ukuqapha umfutho wakho wegazi futhi banikeze ukwelashwa uma kudingeka.

Ngesikhathi ulinde usizo lwezokwelapha, lalela phansi futhi gwema ukunyakaza okungazelelwe. Vumela othile ahlale nawe uma kungenzeka, futhi ungaqhubi imoto noma usebenzise imishini kuze kube yilapho uhlolwe uchwepheshe wezempilo.

Kufanele Ngenzeni Uma Ngingaphuthelwa Umthamo We-Perindopril?

Uma uphuthelwa umthamo we-perindopril, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esijwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungabangela ukuthi umfutho wakho wegazi wehle kakhulu. Ukuthatha imithamo ephindwe kabili kungaba yingozi futhi kungase kubangele imiphumela emibi engathi sína.

Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi zocingo noma ukusebenzisa umhleli wamaphilisi ukukusiza ukuthi ukhumbule. Ukuthatha imithamo yansuku zonke ngokuqhubekayo kubalulekile ekulawuleni umfutho wegazi oqhubekayo.

Ngingayeka Nini Ukuthatha I-Perindopril?

Kufanele uyeke kuphela ukuthatha i-perindopril ngaphansi kokuqondisa kukadokotela wakho. Umfutho wegazi ophezulu nezimo zenhliziyo ngokuvamile zidinga ukwelashwa kwesikhathi eside, futhi ukuyeka imithi kungazelelwe kungabangela ukuthi umfutho wakho wegazi ukhuphuke ngendlela eyingozi.

Udokotela wakho angase acabangele ukunciphisa umthamo wakho noma ukuyeka imithi uma wenze izinguquko ezinkulu zokuphila eziye zathuthukisa impilo yakho yenhliziyo nemithambo yegazi. Kodwa-ke, lesi sinqumo sidinga ukuqapha ngokucophelela futhi akufanele senziwe ngaphandle kokuqondiswa kwezokwelapha.

Uma uhlangabezana nemiphumela emibi ekwenza ufune ukuyeka imithi, khuluma nodokotela wakho mayelana nezinye izindlela kunokuyeka ngokwakho. Kukhona imithi eminingi esebenzayo yomfutho wegazi etholakalayo, futhi udokotela wakho angakusiza ukuthi uthole eyodwa ekusebenzela kangcono.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Perindopril?

Ungaphuza utshwala ngokulinganisela ngenkathi uthatha i-perindopril, kodwa kufanele uqaphele njengoba utshwala bungathuthukisa imiphumela yokwehlisa umfutho wegazi yomuthi. Le nhlanganisela ingakwenza uzizwe unesiyezi noma unomuzwa wokukhathala kunokujwayelekile.

Qala ngezilinganiso ezincane zotshwala ukuze ubone ukuthi umzimba wakho usabela kanjani, futhi gwema ukuphuza amanani amakhulu. Uma uzizwa unesiyezi, ubuthakathaka, noma ungazizwa kahle ngemva kokuphuza ngenkathi use-perindopril, gwema utshwala noma unciphise ukuthatha kwakho ngokuqhubekayo.

Khumbula ukuthi ukusetshenziswa kotshwala ngokweqile kungakhuphula umfutho wegazi ngokuhamba kwesikhathi, okusebenza ngokumelene nezinzuzo zokuthatha i-perindopril. Ukuphuza utshwala ngokulinganisela ngokuvamile kuchazwa njengokungaphezu kwesisodwa ngosuku kwabesifazane kanye neziphuzo ezimbili ngosuku kwabesilisa.