Yini i-Prednisone: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Prednisone iyimithi eyenziwe ngamakhemikhali e-corticosteroid elingisa i-cortisol, i-hormone umzimba wakho owenza ngokwemvelo ezinqeni ze-adrenal. Lo muthi onamandla olwa nokuvuvukala usiza ukunciphisa ukuvuvukala, ukuthulisa amasosha omzimba asebenza ngokweqile, nokuphatha izimo ezihlukahlukene zempilo kusukela ekungezwani komzimba kuya ezifweni ze-autoimmune.

Udokotela wakho angase akubhalele i-prednisone uma umzimba wakho udinga usizo olwengeziwe ekulawuleni ukuvuvukala noma uma amasosha akho omzimba ehlasela izicubu ezinempilo. Ngenkathi iyimithi esebenza kahle kakhulu, ukuqonda ukuthi isebenza kanjani nokuthi yini ongayilindela kungakusiza ukuyisebenzisa ngokuphepha nangokuzethemba.

Isetshenziselwani i-Prednisone?

I-Prednisone iphatha izinhlobo eziningi zezimo lapho ukuvuvukala noma impendulo yamasosha omzimba asebenza ngokweqile kubangela izinkinga. Udokotela wakho uyayibhala ukuze anciphise ngokushesha ukuvuvukala futhi athulise amasosha omzimba wakho uma esebenza kanzima kakhulu noma ehlasela izinto ezingalungile.

Lo muthi uvame ukusetshenziselwa izinhlobo eziningana zezimo zempilo. Nawa amaphuzu amakhulu lapho i-prednisone ibonakala isiza kakhulu:

• Ukungezwani komzimba: Ukungezwani komzimba okukhulu, ukugcwala komoya we-asthma, nezimo zesikhumba ezibangelwa ukungezwani komzimba
• Izimo ze-Autoimmune: I-rheumatoid arthritis, i-lupus, nesifo samathumbu esivuvukalayo
• Izinkinga zesikhumba: I-Eczema, i-psoriasis, ne-dermatitis enkulu
• Izinkinga zokuphefumula: Isifo esingamahlalakhona sokuvinjelwa kwamaphaphu (COPD) ne-asthma enkulu
• Izifo zegazi: Izinhlobo ezithile ze-anemia kanye nokubala kwamaplatelet okuphansi
• Ukwelashwa komdlavuza: Ukuphatha imiphumela emibi nokwelapha imidlavuza ethile yegazi

Umhlinzeki wakho wezempilo uzonquma umthamo ofanele nobude besikhathi ngokuya ngesimo sakho esithile nokuthi umzimba wakho usabela kanjani ekwelashweni. Umgomo uhlala ukusebenzisa umthamo ophansi osebenzayo isikhathi esifushane ngangokunokwenzeka.

Isebenza kanjani i-Prednisone?

I-Prednisone isebenza ngokulingisa izenzo ze-cortisol, i-hormone ezenziwa amaglandla akho e-adrenal nsuku zonke. Uma uthatha i-prednisone, ihamba ngegazi lakho bese ibopha kuma-receptors akhethekile emzimbeni wakho wonke, itshela amasosha akho omzimba ukuthi azole futhi anciphise ukuvuvukala.

Cabanga ngokuvuvukala njengesistimu ye-alamu yomzimba wakho ekhala. Ngezinye izikhathi le alamu iyasiza, njengoba nje une-infection. Kodwa kwezinye izikhathi, i-alamu iyaqhubeka nokukhala ngisho nalapho kungekho ngozi yangempela, okubangela ubuhlungu, ukuvuvukala, nokulimala kwezicubu.

I-Prednisone ngokuyisisekelo ivala ivolumu kulesi simiso se-alamu. Inciphisa ukukhiqizwa kwamakhemikhali avuvukalisayo futhi ivimbela amaseli omzimba ukuthi angahlangani ezindaweni lapho abangela khona izinkinga. Yingakho ungase uqaphele ubuhlungu obuncane, ukuvuvukala, nobubomvu kungakapheli amahora noma izinsuku uqale umuthi.

Njenge-corticosteroid enamandla aphakathi nendawo, i-prednisone inamandla kune-hydrocortisone kodwa ayinamandla kangako kunemithi efana ne-dexamethasone. Lokhu kuyenza ibe yindlela enhle ephakathi nendawo yezimo eziningi.

Kufanele Ngiyithathe Kanjani I-Prednisone?

Thatha i-prednisone ngendlela eqondile udokotela wakho ayichazayo, ngokuvamile kanye ngosuku ekuseni ngokudla noma ubisi. Ukuyithatha ekuseni kusiza ukufanisa isigqi somzimba wakho esivamile se-cortisol futhi kunganciphisa izinkinga zokulala ezinye izikhathi ezenzeka ngalo muthi.

Ukudla noma ubisi kusiza ukuvikela umugqa wesisu sakho ekucasukeni. Uma uthatha imithamo eminingi ngosuku, yihlukanise ngokulinganayo futhi ngaso sonke isikhathi uyithathe ngento esiswini sakho. Isnakhi esilula noma ingilazi yobisi isebenza kahle uma ungakalungeli ukudla okugcwele.

Gwinya amaphilisi wonke ngamanzi amaningi. Uma unenkinga yokugwinya amaphilisi, buza usokhemisi wakho mayelana namafomu olwelo noma ukuthi kuphephile yini ukuchoboza amaphilisi akho athile. Ezinye izindlela zingahlukaniswa, kodwa ezinye zinezendlalelo ezikhethekile ezingafanele ziphule.

Ungayeki ukuthatha i-prednisone ngokuzumayo, ikakhulukazi uma ubuthatha isikhathi esingaphezu kwamasonto ambalwa. Udokotela wakho uzokwenza uhlelo lokunciphisa kancane kancane umthamo wakho, enikeza amagciwane akho e-adrenal isikhathi sokuqala ukwenza i-cortisol futhi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Prednisone?

Ubude bokwelashwa nge-prednisone buhlukahluka kakhulu kuye ngesimo sakho nokuthi usabela kanjani emuthini. Ukusetshenziswa kwesikhashana kungase kuthatha izinsuku ezimbalwa nje kuya emavikini, kuyilapho izimo ezingapheli zingase zidinge izikhathi zokwelashwa ezinde ngokugadwa ngokucophelela.

Ezimweni ezinzima njengokungezwani komzimba okukhulu noma ukuqubuka kwe-asthma, ungase uthathe i-prednisone izinsuku eziyi-3-10. Udokotela wakho uvame ukunquma umthamo ophezulu ekuqaleni, bese ewunciphisa kancane kancane njengoba izimpawu zakho zithuthuka.

Izimo ezingapheli njenge-rheumatoid arthritis noma isifo samathumbu esivuvukalayo zingase zidinge izikhathi zokwelashwa ezinde. Kulezi zimo, udokotela wakho uzosebenza ukuthola umthamo ophansi ogcina izimpawu zakho zilawulwa ngenkathi kuncishiswa imiphumela emibi.

Umhlinzeki wakho wokunakekelwa kwezempilo uzohlola njalo isidingo sakho se-prednisone futhi alungise uhlelo lwakho lokwelashwa ngokufanele. Bazocabangela izinto ezinjengokuthi isimo sakho silawulwa kahle kangakanani, noma yimiphi imiphumela emibi oyitholayo, nokuthi ngabe ezinye izindlela zokwelapha zingase zisebenze kangcono ekuphathweni kwesikhathi eside.

Yini Imiphumela Emibi Ye-Prednisone?

I-Prednisone ingabangela imiphumela emibi ehlukahlukene, nakuba kungathi akubona bonke abayitholayo. Amathuba nobukhulu bemiphumela emibi avame ukuncika kumthamo nokuthi uthatha isikhathi esingakanani umuthi. Imiphumela eminingi emibi yesikhashana iyaphathwa futhi iyabuyiseka.

Imiphumela emibi evamile ongase uyibone ihlanganisa ukwanda kwesifiso sokudla, ukukhuluphala, izinguquko zemizwa, nobunzima bokulala. Le miphumela yenzeka ngoba i-prednisone ithinta izinhlelo eziningi emzimbeni wakho, hhayi nje impendulo evuvukalayo ozama ukuyelapha.

Nawa imiphumela emibi ebikwa kaningi:

• Ukwanda kwesifiso sokudla nokukhuluphala: Ikakhulukazi ebusweni, entanyeni, nasemkhatsini womzimba
• Ushintsho lwemizwa: Ukuzizwa unamandla kakhulu, ukhathazekile, noma uthukuthele kunokujwayelekile
• Izinkinga zokulala: Ukuhluleka ukulala noma ukuhlala ulele
• Izinkinga zokugaya ukudla: Ukuphathwa yisisu, isicanucanu, noma ukwanda kwe-asidi esiswini
• Ukugcinwa kwamanzi: Ukuvuvukala ezandleni, ezinyaweni, noma ebusweni
• Ukwanda koshukela wegazi: Kubaluleke kakhulu uma unesifo sikashukela

Ukusetshenziswa kwesikhathi eside kungaholela emiphumeleni emibi kakhulu, yingakho odokotela bekhetha ukusebenzisa i-prednisone isikhathi esifushane ngangokunokwenzeka. Lokhu kungabandakanya ukuncipha kwamathambo, ukwanda kwengozi yokutheleleka, umfutho wegazi ophezulu, kanye noshintsho ekusabalalisweni kwamafutha.

Imiphumela emibi engavamile kodwa ebucayi kakhulu ihlanganisa izinguquko ezinzima zemizwa, izinkinga zombono, ubuhlungu obukhulu besisu, noma izimpawu zokutheleleka njengomkhuhlane nokukhwehlela okuqhubekayo. Xhumana nodokotela wakho ngokushesha uma uhlangabezana nanoma yiziphi zalezi zimpawu.

Ubani Ongafanele Athathwe I-Prednisone?

Abantu abathile badinga ukugwema i-prednisone noma bayisebenzise ngokuqapha okwengeziwe ngenxa yezingozi ezengeziwe. Udokotela wakho uzohlola ngokucophelela izinzuzo ngokumelene nezinkinga ezingaba khona ngaphambi kokunquma lo muthi.

Abantu abanezifo ezisebenzayo ngokuvamile kufanele bagweme i-prednisone ngoba icindezela amasosha omzimba, okwenza kube nzima ukuthi umzimba wakho ulwe namagciwane, amagciwane, noma amakhowe. Kodwa-ke, kwezinye izimo, odokotela bangase bayinikeze kanye nama-antibiotics ezimweni ezithile.

Izimo eziningana zezempilo zidinga ukucatshangelwa okukhethekile ngaphambi kokuqala i-prednisone:

• Isifo sikashukela: I-Prednisone ingakhuphula amazinga kashukela egazini kakhulu
• Umfutho wegazi ophezulu: Umuthi ungenza umfutho wegazi ophezulu ube mubi kakhulu
• I-Osteoporosis: Ukusetshenziswa kwesikhathi eside kungaqhubeka nokwenza amathambo abuthakele
• Izilonda zesisu: I-Prednisone ingathukuthelisa ulwelwesi lwesisu
• Izimo zempilo yengqondo: Kungase kwenze ukucindezeleka, ukukhathazeka, noma i-psychosis kube kubi kakhulu
• Isifo sesibindi noma sezinso: Lezi zitho zicubungula futhi ziqede umuthi
• Isifo senhliziyo: Ukugcinwa kwamanzi kanye nezinguquko zomfutho wegazi kungayiqeda inhliziyo

Uma ukhulelwe noma uncelisa, xoxa ngezingozi nezinzuzo nodokotela wakho. Ngenkathi i-prednisone ingasetshenziswa ngesikhathi sokukhulelwa uma kudingeka, idinga ukuqapha ngokucophelela kokubili umama nomntwana.

Amagama Omkhiqizo we-Prednisone

I-Prednisone itholakala ngaphansi kwamagama amaningi omkhiqizo, nakuba inguqulo ejwayelekile isebenza ngempumelelo. Amagama omkhiqizo ajwayelekile afaka i-Rayos, i-Prednisone Intensol, kanye nezinguqulo ezihlukahlukene eziqondene nomkhiqizi.

I-Rayos iyindlela yokukhishwa okubambezelekile eyenzelwe ukukhulula umuthi kamuva emini, okungaba usizo ezimweni ezinjenge-rheumatoid arthritis lapho ukuqina kwasekuseni kuyinkinga. I-Prednisone Intensol iyindlela ewuketshezi egxilile okulula ukuyilinganisa ukuze kutholakale umthamo oqondile.

Noma ngabe uthola i-prednisone yegama lomkhiqizo noma ejwayelekile akuthinti ukusebenza komuthi. Izinguqulo ezivamile zithatha ukuhlolwa okufanayo okuqinile futhi ziqukethe isithako esifanayo esisebenzayo njengezinguqulo zegama lomkhiqizo.

Ezinye izindlela ze-Prednisone

Kukhona ezinye izindlela ze-prednisone, kuye ngesimo sakho esithile kanye nemigomo yokwelashwa. Udokotela wakho angase acabangele lezi zinketho uma i-prednisone ingakulungele noma uma uhlangabezana nemiphumela emibi enezinkinga.

Ezinye izinhlobo zama-corticosteroids afana ne-methylprednisolone, i-hydrocortisone, noma i-dexamethasone zingase zisebenze kangcono ezimweni ezithile. Ngayinye inamazinga ahlukene wamandla nobude besikhathi sokusebenza, okuvumela odokotela ukuthi balungise ukwelashwa kwakho.

Ezinye izindlela ezingezona ze-steroidal zihlanganisa:

• Imithi yokulwa nezifo ze-rheumatic (DMARDs): Ezimweni ze-autoimmune
• Imithi ye-Biologic: Iqondise izingxenye ezithile zomzimba wokuzivikela komzimba
• Ukwelashwa kwendawo: Ezimweni zesikhumba, ukugwema imiphumela yesistimu
• Ama-immunosuppressants aqondiwe: Njenge-methotrexate ezimweni ezithile

Enye indlela engcono kakhulu incike ekuxilongweni kwakho okuthile, impilo yonke, nokuthi usabele kanjani ekwelashweni kwangaphambilini. Umhlinzeki wakho wezempilo uzosiza ekunqumeni ukuthi iyiphi inketho enikeza ibhalansi engcono kakhulu yokusebenza kahle nokuphepha esimweni sakho.

Ingabe i-Prednisone ingcono kune-Methylprednisolone?

I-Prednisone ne-methylprednisolone zombili ziyi-corticosteroids esebenzayo, kodwa zinezici ezihlukile ezenza ngamunye afaneleke kakhulu ezimweni ezithile. Akukho noyedwa othi “ungcono” kunomunye.

I-Methylprednisolone inamandla amancane kune-prednisone, okusho ukuthi udinga umthamo ophansi ukuze uzuze umphumela ofanayo wokulwa nokuvuvukala. Futhi inethonya elincane ekulinganiseni ama-electrolyte, okungasiza abantu abanezimo zenhliziyo noma izinso.

I-Prednisone ivame ukunqunywa ngomlomo futhi ivame ukukhethwa ekwelashweni kwesikhathi eside ngoba ifundwe kahle futhi ishibhile. I-Methylprednisolone ivame ukusetshenziswa ezindaweni zasemtholampilo, ikakhulukazi uma inikezwa ngemithambo.

Udokotela wakho uzokhetha phakathi kwale mithi ngokusekelwe esimweni sakho esithile, ubukhulu bezimpawu zakho, kanye nephrofayili yakho yezempilo yomuntu ngamunye. Zombili le mithi zisebenza ngezindlela ezifanayo futhi zinezinhlu zokusebenza ezingafani.

Imibuzo Evame Ukubuzwa Mayelana ne-Prednisone

Q1. Ingabe i-Prednisone iphephile kubantu abanesifo sikashukela?

I-Prednisone ingasetshenziswa kubantu abanesifo sikashukela, kodwa idinga ukuqapha ushukela wegazi ngokucophelela futhi ngokuvamile kudingeka ukulungiswa kwemithi. Lo muthi ungakhuphula kakhulu amazinga kashukela egazini, ngezinye izikhathi ngendlela emangalisayo, ngisho nakubantu abanesifo sikashukela esilawulwa kahle.

Udkt wakho cishe uzoncoma ukuthi uhlole ushukela wakho wegazi kaningi ngenkathi uthatha i-prednisone. Ungase udinge ukwanda okwesikhashana kwemithi yakho yesifo sikashukela noma imithamo ye-insulin ukuze ugcine ukulawulwa okuhle kwe-glucose.

Sebenza eduze nethimba lakho lezempilo ukuze uthuthukise uhlelo lokuqapha. Abantu abaningi abanesifo sikashukela bangayisebenzisa ngokuphepha i-prednisone lapho izinzuzo zidlula izingozi, kodwa idinga ukuphathwa ngendlela eqhubekayo.

Q2. Kufanele ngenzeni uma ngiphuzile i-Prednisone eningi ngengozi?

Uma ngengozi uphuze i-prednisone eningi kunaleyo ebekiwe, ungangeni ekuqeqeshweni, kodwa xhumana nomhlinzeki wakho wezempilo noma usokhemisi ukuze uthole isiqondiso. Umthamo owodwa owengeziwe akunakwenzeka ukuthi ulimaze kakhulu, kodwa kubalulekile ukuthola iseluleko esivela ochwepheshe.

Ziqaphele izimpawu ezinjengokugula okukhulu, ukuhlanza, isiyezi, noma izinguquko ezingavamile zemizwa. Uma uhlangabezana nalezi zimpawu noma uphuze okuningi kakhulu kunokuba kubekiwe, funa ukwelashwa ngokushesha.

Ungazami ukukhokhela ngokweqa umthamo wakho olandelayo noma uphuze okuncane. Kunalokho, buyela esimisweni sakho esijwayelekile sokulinganisa njengoba uqondiswa ngumhlinzeki wakho wezempilo. Bangase bafune ukukuqapha eduze izinsuku ezimbalwa.

Q3. Kufanele ngenzeni uma ngiphuthelwe umthamo we-Prednisone?

Uma uphuthelwe umthamo we-prednisone, yiphuzeni ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Ungalokothi uphuze imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe. Lokhu kungakhuphula ingozi yakho yemiphumela emibi ngaphandle kokuhlinzeka ngezinzuzo ezengeziwe.

Uma ukhohlwa njalo imithamo, cabangela ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi. Ukuthatha imithi njalo kusiza ukugcina amazinga emithi ezinzile emzimbeni wakho futhi kunciphisa ingozi yokuthi izimpawu ziqale kabusha.

Q4. Ngingayeka nini ukuthatha i-Prednisone?

Kufanele uyeke ukuthatha i-prednisone ngaphansi kwesiqondiso sikadokotela wakho kuphela, ikakhulukazi uma ubuthatha isikhathi esingaphezu kwamasonto ambalwa. Ukuyeka ngokuphazima kungabangela izimpawu zokuhoxisa kanye nezinkinga eziyingozi.

Udkt wakho ngokuvamile uzokwenza isimiso sokunciphisa umthamo esinciphisa kancane umthamo wakho ezinsukwini noma emasontweni. Lokhu kunika amaglands akho e-adrenal isikhathi sokuthi aqale ukukhiqiza i-cortisol evamile.

Izimpawu zokuthi kungase kube yisikhathi sokuxoxa ngokuyeka zihlanganisa ukulawulwa okuhle kwezimpawu, imiphumela emibi ekhathazayo, noma ukutholakala kwezinye izindlela zokwelapha. Umhlinzeki wakho wezempilo uzohlola isimo sakho ngasinye futhi anqume indlela ephephe kakhulu.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Prednisone?

Ngokuvamile kungcono ukugwema noma ukukhawulela utshwala ngenkathi uthatha i-prednisone. Kokubili utshwala ne-prednisone kungathukuthelisa umugqa wesisu sakho, okwandisa ingozi yezilonda nezinkinga zokugaya ukudla uma kusetshenziswa ndawonye.

Utshwala bungase futhi lwenze kube kubi eminye yemiphumela emibi ye-prednisone, okuhlanganisa izinguquko zemizwa, izinkinga zokulala, nokuguquguquka koshukela wegazi. Uma unesifo sikashukela, le nhlanganisela ingenza ukulawulwa kukashukela wegazi kube yinselele.

Uma ukhetha ukuphuza ngezikhathi ezithile, yenza kanjalo ngokulinganisela futhi nokudla ukuze unciphise ukucasuka kwesisu. Xoxa ngokusebenzisa kwakho utshwala nodokotela wakho ukuze bakwazi ukukunikeza isiqondiso esiqondene nawe esisekelwe esimweni sakho sempilo kanye nohlelo lokwelapha.