Yini i-Sitagliptin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Sitagliptin iyimithi kadokotela esiza ukuphatha isifo sikashukela sohlobo 2 ngokugcina amazinga kashukela egazini lakho ebangeni elinempilo. Ingaphansi kweqembu lemithi ebizwa ngokuthi ama-DPP-4 inhibitors, asebenza ngobumnene nezinhlelo zomzimba wakho zemvelo ukuze kuthuthukiswe ukulawulwa kukashukela egazini ngaphandle kokubangela ukwehla okukhulu.

Le mithi isibe inketho ethenjwayo kubantu abaningi abanesifo sikashukela ngoba ivame ukubekezeleleka kahle futhi ingasetshenziswa yodwa noma kanye nezinye izindlela zokwelapha isifo sikashukela. Ukuqonda ukuthi i-sitagliptin isebenza kanjani nokuthi okulindelekile kungakusiza uzizwe uqiniseka kakhulu ngohlelo lwakho lokuphatha isifo sikashukela.

Yini i-Sitagliptin?

I-Sitagliptin iyimithi yomlomo yesifo sikashukela esiza umzimba wakho ukuthi uphathe kangcono amazinga kashukela egazini usuku lonke. Isebenza ngokuvimba i-enzyme ebizwa ngokuthi i-DPP-4, evumela umzimba wakho ukuthi ukhiqize i-insulin eningi uma uyidinga kanye ne-glucose encane uma ungayidingi.

Cabanga nge-sitagliptin njengomsizi olusizo olungisa kahle uhlelo lomzimba wakho lokulawula ushukela egazini. Ngokungafani neminye imithi yesifo sikashukela engabangela ukuthi ushukela wakho wegazi wehle kakhulu, i-sitagliptin yakhelwe ukuthi isebenze kuphela uma ushukela wakho wegazi uphakeme, okwenza kube inketho enobumnene kubantu abaningi.

Le mithi itholakala njengamaphilisi owathatha ngomlomo, ngokuvamile kanye ngosuku. Ivame ukunqunywa lapho ukudla nokuzivocavoca kuphela kunganele ukugcina amazinga kashukela egazini lapho kufanele abe khona, noma lapho eminye imithi yesifo sikashukela idinga ukwesekwa okwengeziwe.

Isetshenziselwani i-Sitagliptin?

I-Sitagliptin isetshenziswa ikakhulukazi ukwelapha isifo sikashukela sohlobo 2 kubantu abadala. Isiza ukwehlisa amazinga kashukela egazini uma ephakeme kakhulu, okungavimbela kokubili ukungakhululeki okusheshayo kanye nezinkinga zesikhathi eside zesifo sikashukela.

Udktela wakho angase ancome i-sitagliptin uma usanda kutholakala nesifo sikashukela sohlobo 2 futhi izinguquko zokuphila azikabi ngcono ekulawuleni ushukela wakho wegazi. Ivamise futhi ukwengezwa ezinhlelweni zokwelapha isifo sikashukela ezikhona lapho eminye imithi inganikezi ukulawula okwanele yodwa.

Lo muthi ungaba usizo ikakhulukazi kubantu abahlangabezana nokukhuphuka kukashukela wegazi ngemva kokudla. Njengoba i-sitagliptin isebenza ngokusabela komzimba wakho kwemvelo ku-insulin, ingasiza ekuthambiseni lokhu kukhuphuka kwe-glucose ngemva kokudla ngaphandle kokubangela izigameko eziyingozi zikashukela ophansi wegazi.

Kwezinye izimo, i-sitagliptin ingase inikezwe njengengxenye yokwelashwa okuhlanganisiwe kanye ne-metformin, sulfonylureas, noma i-insulin. Le ndlela ivumela ithimba lakho lokunakekelwa kwezempilo ukuthi lenze uhlelo lokwelapha olwenzelwe wena olubhekana nezidingo zakho ezithile kanye nephrofayili yezempilo.

Isebenza Kanjani I-Sitagliptin?

I-Sitagliptin isebenza ngokuvimba i-enzyme ebizwa nge-DPP-4 evame ukwephula amahomoni awusizo ohlelweni lwakho lokugaya ukudla. Lapho la mahomoni ehlala isikhathi eside, angasebenza kangcono ekuphatheni ushukela wakho wegazi.

Nakhu okwenzekayo uma uthatha i-sitagliptin: ngemva kokudla, amathumbu akho akhipha amahomoni abizwa ngokuthi ama-incretins athumela isignali emzimbeni wakho ukuthi ukhiqize i-insulin futhi utshele isibindi sakho ukuthi siyeke ukukhiqiza i-glucose eyengeziwe. Ngokuvamile, i-enzyme ye-DPP-4 yephula ngokushesha la mahomoni awusizo, kodwa i-sitagliptin imisa lokhu kwephulwa.

Le ndlela yenza i-sitagliptin lokho odokotela abakubiza ngokuthi umuthi

I-Sitagliptin ithathwa njengomuthi wokwelapha isifo sikashukela onesilinganiso esiphakathi nendawo kunokuba omkhulu. Nakuba kungenzeka ingehlisi ushukela wegazi ngendlela emangalisayo njenge-insulin noma eminye imithi, isenzo sayo esithambile kanye nengozi ephansi yemiphumela emibi kuyenza ithuluzi elibalulekile kubantu abaningi abanesifo sikashukela sohlobo 2.

Kufanele Ngiyithathe Kanjani I-Sitagliptin?

I-Sitagliptin ivamise ukuthathwa kanye ngosuku, futhi ungayithatha nokudla noma ngaphandle kokudla. Abantu abaningi bakuthola kulula ukuyithatha ngesikhathi esifanayo nsuku zonke ukuze basize ukukhumbula nokugcina amazinga egazi emithi eqhubekayo.

Akudingeki ukhathazeke ngesikhathi sokuthatha i-sitagliptin nokudla ngoba ukudla akuthinti ngendlela ebonakalayo ukuthi umzimba wakho uyayithatha kanjani. Abanye abantu bakhetha ukuyithatha ngesidlo sasekuseni ukuze basungule umkhuba, kanti abanye bakuthola kulula ukuyithatha ngesidlo sakusihlwa noma ngesikhathi sokulala.

Ngaso sonke isikhathi gwinya ithebhulethi yonke ngamanzi. Ungayichobozi, uhlafune, noma uyiphule ithebhulethi, ngoba lokhu kungathinta ukuthi umuthi ukhululwa kanjani emzimbeni wakho. Uma unenkinga yokugwinya amaphilisi, khuluma nomphathi wakho wamaphilisi noma udokotela mayelana namaqhinga angasiza.

Umthamo ovamile wokuqala yi-100 mg kanye ngosuku, nakuba udokotela wakho engase alungise lokhu ngokusekelwe ekusebenzeni kwezinso zakho nakwezinye izinto zempilo. Uma unezinkinga zezinso, ungase uthole umthamo ophansi ukuze uqinisekise ukuthi umuthi ucutshungulwa ngokuphepha ngumzimba wakho.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Sitagliptin?

I-Sitagliptin ngokuvamile iyimithi yesikhathi eside ozoqhubeka uyithatha uma nje isiza ukuphatha isifo sakho sikashukela ngempumelelo. Uhlobo 2 lwesifo sikashukela yisimo esingapheli esidinga ukuphathwa okuqhubekayo, ngakho abantu abaningi bahlala emithini yabo yesifo sikashukela unomphela.

Udktela wakho uzoqapha ukuthi i-sitagliptin ikusebenzela kahle kangakanani ngokuhlolwa kwegazi njalo, ikakhulukazi amazinga akho e-A1C, abonisa ushukela wakho wegazi omaphakathi ezinyangeni ezi-2-3 ezedlule. Lokhu kuhlolwa kuvame ukwenzeka njalo ezinyangeni ezi-3-6 futhi kusiza ukunquma ukuthi uhlelo lwakho lwamanje lokwelashwa luyifeza yini imigomo yakho.

Abanye abantu bangase badinge ukwengeza eminye imithi ohlelweni lwabo ngokuhamba kwesikhathi, njengoba isifo sikashukela singaqhubeka futhi sidinge ukwesekwa okwengeziwe. Lokhu akusho ukuthi i-sitagliptin isiyekile ukusebenza, kodwa kunalokho izidingo zomzimba wakho zishintshile, okuyinto ejwayelekile ngokuphelele ngalesi simo.

Ungayeki ukuthatha i-sitagliptin ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Noma ngabe uzizwa kahle futhi ushukela wakho wegazi ubonakala uzinzile, ukuyeka imithi yesifo sikashukela kungazelelwe kungabangela amazinga kashukela wakho wegazi ukuthi anyuke ngokushesha, okungenzeka kuholele ezinkingeni ezinzima.

Yiziphi Imiphumela Eceleni ye-Sitagliptin?

Abantu abaningi bayayibekezelela kahle i-sitagliptin, kodwa njengayo yonke imithi, ingabangela imiphumela emibi kwabanye abantu. Izindaba ezinhle ukuthi imiphumela emibi engathí sina ayivamile, futhi abantu abaningi ababi nayo imiphumela emibi nhlobo.

Ake siqale ngemiphumela emibi ejwayelekile ongase uyithole, evame ukuthinta abantu abangaphansi koyedwa kwabayi-10 abathatha umuthi:

• Ukutheleleka kwepheshana eliphezulu lokuphefumula njengomkhuhlane noma ukutheleleka kwemigudu yamathambo
• Ikhanda elivame ukuba lincane futhi lesikhashana
• Ikhala eligcwele noma eligelezayo
• Umphimbo obuhlungu
• Ukuphazamiseka kwesisu noma isicanucanu

Le miphumela emibi ejwayelekile ivame ukuba mncane futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi. Abantu abaningi bathola ukuthi bangaqhubeka nokuthatha i-sitagliptin ngaphandle kokungakhululeki okukhulu.

Kukhona nemiphumela emibi engavamile kodwa engathi sína edinga ukunakekelwa kwezokwelapha ngokushesha. Ngenkathi lokhu kwenzeka ngezikhathi ezithile, kubalulekile ukwazi ukuthi yini okufanele uyibheke:

• Ubuhlungu obukhulu besisu obungase bubonise i-pancreatitis (ukuqubuka kwamanyikwe)
• Isicanucanu esiqhubekayo nokuhlanza
• Ukuphendula okukhulu komzimba okuhlanganisa ukuqubuka, ukuluma, ukuvuvukala, noma ubunzima bokuphefumula
• Ubuhlungu obukhulu emalungeni noma obungathuthuki
• Ukusabela kwesikhumba okungavamile noma ukuqhekeka

Uma uhlangabezana nanoma yiziphi zalezi zimpawu ezinzima, xhumana nomhlinzeki wakho wezempilo ngokushesha noma funa ukunakekelwa kwezempilo okuphuthumayo.

Ngokungavamile kakhulu, i-sitagliptin iye yahlotshaniswa nesimo esibizwa ngokuthi i-bullous pemphigoid, esibangela ukuqhekeka kwesikhumba. Lesi simo sesikhumba esibi sidinga ukunakekelwa kwezempilo ngokushesha kodwa sithinta abantu abangaphansi kuka-1 kwabangu-10,000 abathatha umuthi.

Ubani Ongafanele Athole I-Sitagliptin?

I-Sitagliptin ayifanele wonke umuntu onesifo sikashukela. Abantu abanesifo sikashukela sohlobo 1 noma i-diabetic ketoacidosis akufanele bathathe lo muthi, njengoba wenzelwe ngqo uhlobo 2 lwesifo sikashukela futhi ngeke unikeze ukwesekwa kwe-insulin okudingekayo kulezi zimo.

Kufanele utshele udokotela wakho nganoma yikuphi ukungezwani komzimba onakho ngaphambi kokuqala i-sitagliptin. Uma uke waba nokusabela komzimba ku-sitagliptin noma kunoma yimuphi umuthi we-DPP-4 inhibitor esikhathini esidlule, lo muthi cishe awuphephile kuwe.

Abantu abanezimo ezithile zezempilo badinga ukucatshangelwa okukhethekile ngaphambi kokuthatha i-sitagliptin. Udokotela wakho uzodinga ukwazi ukuthi ngabe unayo:

• Isifo sezinso noma ukusebenza kwezinso okuncishisiwe
• Umlando we-pancreatitis (ukuqubuka kwamanyikwe)
• Izinkinga zenhliziyo noma ukuhluleka kwenhliziyo
• Amathambo e-gallstones noma isifo se-gallbladder
• Umlando wobuhlungu obukhulu emalungeni noma i-arthritis

Lezi zimo aziwuvimbeli ngokuzenzakalelayo ukuthatha i-sitagliptin, kodwa zingase zidinge ukulungiswa komthamo noma ukuqapha okuseduze ukuze kuqinisekiswe ukuphepha kwakho.

Uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa, xoxa lokhu nomhlinzeki wakho wezempilo. Ngenkathi i-sitagliptin ingakabonakali ibanga ingozi ngesikhathi sokukhulelwa, udokotela wakho angase ancome ezinye izindlela zokuphatha isifo sikashukela ngalesi sikhathi.

Amagama Omkhiqizo we-Sitagliptin

I-Sitagliptin itholakala ngaphansi kwegama lomkhiqizo elithi Januvia, okuyilona fomu elivame kakhulu ukunconywa lolu lwazi. I-Januvia iqukethe i-sitagliptin njengesithako sayo esisebenzayo futhi yenziwa yi-Merck & Co.

Ungase futhi uhlangane nemithi ehlanganisiwe ehlanganisa i-sitagliptin kanye neminye imithi yesifo sikashukela. I-Janumet ihlanganisa i-sitagliptin ne-metformin, kuyilapho i-Janumet XR iyinguqulo ekhishwe isikhathi eside yale nhlanganisela ethathwa kaningi.

Izinhlobo ze-generic ze-sitagliptin ziye zatholakala emazweni amaningi, okwenza imithi ibe ngcono. Lezi zinhlobo ze-generic ziqukethe isithako esifanayo esisebenzayo futhi zisebenza ngempumelelo njengenguqulo yegama lomkhiqizo.

Noma ngabe uthola i-sitagliptin yegama lomkhiqizo noma i-generic ngokuvamile kuncike ekuhlinzekweni kwakho komshwalense kanye nezintandokazi zekhemisi. Zombili izinhlobo zisebenza ngokulinganayo, ngakho-ke ungezwa uqiniseka ngohlobo olunjalo udokotela wakho alubhala.

Ezinye izindlela ze-Sitagliptin

Uma i-sitagliptin ingafaneleki kuwe, eminye imithi yesifo sikashukela ingahlinzeka ngezinzuzo ezifanayo. Ezinye izithiyo ze-DPP-4 ezifana ne-linagliptin (Tradjenta), i-saxagliptin (Onglyza), kanye ne-alogliptin (Nesina) zisebenza ngendlela efanayo ne-sitagliptin.

Ama-GLP-1 receptor agonists amelela enye ikilasi lemithi yesifo sikashukela esebenza nezinhlelo zakho ze-hormone zemvelo. Lokhu kufaka phakathi imithi efana ne-liraglutide (Victoza), i-semaglutide (Ozempic), kanye ne-dulaglutide (Trulicity), yize lezi zivame ukunikezwa ngemijovo kunemithi yomlomo.

Kubantu abathanda imithi yomlomo, izithiyo ze-SGLT-2 ezifana ne-empagliflozin (Jardiance) kanye ne-canagliflozin (Invokana) zinikeza indlela ehlukile ngokusiza izinso zakho ukususa i-glucose eyeqile ngomchamo. Le mithi ingase futhi inikeze izinzuzo zokuvikela inhliziyo nezinso.

Imithi yesintu yesifo sikashukela efana ne-metformin, i-sulfonylureas, kanye ne-insulin ihlala iyizinketho ezibalulekile zokwelapha kuye ngezidingo zakho ezithile kanye nephrofayili yezempilo. Umhlinzeki wakho wezempilo angasiza ekunqumeni ukuthi imuphi umuthi noma inhlanganisela yemithi ezosebenza kahle esimweni sakho.

Ingabe i-Sitagliptin Ingcono Kune-Metformin?

I-Sitagliptin ne-metformin zisebenza ngendlela ehlukile futhi zivame ukusetshenziswa ndawonye kunokuba zibe ezinye izindlela zokuncintisana. I-Metformin ngokuvamile iyindlela yokuqala yokwelapha uhlobo 2 lwesifo sikashukela ngoba isetshenziswe ngokuphepha amashumi eminyaka futhi inezinzuzo eziqinisekisiwe zempilo yenhliziyo nokuphatha isisindo.

I-Metformin isebenza ikakhulukazi ngokunciphisa inani le-glucose isibindi sakho esikhiqizayo nokuthuthukisa ukuzwela komzimba wakho ku-insulin. Ngokuvamile isebenza kahle ekwehliseni amazinga kashukela egazini kune-sitagliptin yodwa, yingakho ivame ukuba yisisekelo sokwelashwa kwesifo sikashukela.

Nokho, i-sitagliptin inezinzuzo ezithile phezu kwe-metformin kwabanye abantu. Akungenzeki ukuthi ibangele isisu esibuhlungu noma izinkinga zokugaya ukudla, okungaba yizinkinga ezibalulekile nge-metformin. I-Sitagliptin nayo ngokuvamile ayibangeli ukukhuluphala futhi inengozi ephansi kakhulu yokubangela izigameko zikashukela ophansi.

Abantu abaningi bagcina bethatha yomibili imithi ndawonye ngoba bayazwana kahle. Inhlanganisela ye-metformin ne-sitagliptin (etholakala njenge-Janumet) inganikeza ukulawulwa okungcono kashukela egazini kunomuthi ngamunye uwedwa ngenkathi kugcinwa iphrofayili yemiphumela eseceleni ethambile.

Imibuzo Evame Ukubuzwa Mayelana ne-Sitagliptin

Ingabe i-Sitagliptin Iphephile Ngesifo Senhliziyo?

I-Sitagliptin ifundwe kabanzi kubantu abanezifo zenhliziyo futhi ngokuvamile ithathwa njengephephile kulaba bantu. Izivivinyo ezinkulu zomtholampilo zikhombisile ukuthi i-sitagliptin ayikhuphuli ingozi yokuhlaselwa yinhliziyo, ukushaywa unhlangothi, noma ukufa kwenhliziyo nemithambo uma kuqhathaniswa ne-placebo.

Eqinisweni, ukuphatha kahle isifo sakho sikashukela ngemithi efana ne-sitagliptin kungasiza ukuvikela inhliziyo yakho ngokuhamba kwesikhathi. Amazinga kashukela aphezulu egazini ngokuhamba kwesikhathi angalimaza imithambo yegazi futhi andise ingozi yenhliziyo nemithambo, ngakho-ke ukulawula isifo sakho sikashukela kungenye yezinto ezinhle ongazenzela impilo yenhliziyo yakho.

Uma unesifo senhliziyo, udokotela wakho uzocabangela isithombe sakho sempilo yonke lapho enquma imithi yesifo sikashukela. Bangase bakhethe i-sitagliptin ngenxa yemiphumela yayo yenhliziyo nemithambo engathathi hlangothi, noma bangase bakhethe eminye imithi yesifo sikashukela ekhonjiswe ukuthi inikeza ukuvikelwa okwengeziwe kwenhliziyo.

Kufanele Ngenzeni Uma Ngisebenzisa Ngengozi I-Sitagliptin Eningi Kakhulu?

Uma ngengozi uthatha i-sitagliptin eningi kunaleyo ebekiwe, ungesabi. Ngokungafani neminye imithi yesifo sikashukela, i-sitagliptin akunakwenzeka ukuthi ibangele amazinga kashukela aphansi egazini ayingozi ngisho noma uthatha eningi kakhulu, ngoba isebenza kuphela uma ushukela wakho wegazi uphakeme.

Noma kunjalo, kufanele usaxhumane nomhlinzeki wakho wezempilo noma usokhemisi ukuze ubike ukweqisa futhi uthole isiqondiso sokuthi wenzeni ngokulandelayo. Bangase bancomise ukuqapha ushukela wakho wegazi kaningi emahoreni angama-24 alandelayo noma ukubheka noma yiziphi izimpawu ezingavamile.

Uma uthathe i-sitagliptin eningi kakhulu noma uma uhlangabezana nezimpawu ezikhathazayo njengokucasuka okukhulu, ukuhlanza, noma ubuhlungu besisu, funa ukwelashwa ngokushesha. Ngenkathi imiphumela emibi yokweqisa ingavamile, ngaso sonke isikhathi kungcono ukwenza ngokuqapha.

Ukuvimbela ukweqisa imithamo ngengozi esikhathini esizayo, cabangela ukusebenzisa umhleli wamaphilisi noma ukusetha izikhumbuzi zocingo ukukusiza ukuthi ulandelele ukuthi uthathe nini imithi yakho. Lokhu kuyasiza ikakhulukazi uma uthatha imithi eminingi usuku lonke.

Kufanele Ngenzeni Uma Ngeqe Umthamo We-Sitagliptin?

Uma ugeqe umthamo we-sitagliptin, yithathe ngokushesha nje lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo ogeqiwe bese uqhubeka nohlelo lwakho olujwayelekile lokuthatha imithi.

Ungalokothi uthathe imithamo emibili ye-sitagliptin ngesikhathi esisodwa ukuze ulungise umthamo ogeqiwe. Lokhu ngeke kunikeze inzuzo eyengeziwe futhi kungandisa ingozi yakho yemiphumela emibi. Ukulawulwa kwakho ushukela wegazi ngeke kuthinteke kakhulu ngokuqeda umthamo owodwa.

Uma uvame ukukhohlwa ukuthatha imithi yakho, khuluma nomhlinzeki wakho wezempilo mayelana namaqhinga okukusiza ukuthi ukhumbule. Bangase batusa ukuyithatha ngesinye isikhathi sosuku oluhambisana kangcono nomsebenzi wakho wansuku zonke, noma batusa amathuluzi afana nezinhlelo zokusebenza ze-smartphone noma abahleli bamaphilisi.

Ukuqeda imithamo ngezikhathi ezithile akuyona ingozi, kodwa ukukhohlwa njalo ukuthatha imithi yakho yesifo sikashukela kungaholela ekulawulweni okubi kukashukela wegazi ngokuhamba kwesikhathi. Ukunamathela kahle emithini kubalulekile ekuvikeleni izinkinga zesifo sikashukela nokugcina impilo yakho yonke.

Ngingayeka Nini Ukuthatha I-Sitagliptin?

Kufanele uyeke kuphela ukuthatha i-sitagliptin ngaphansi kokuqondiswa ngumhlinzeki wakho wezempilo. Noma ngabe amazinga akho kashukela wegazi athuthuke kakhulu, lokhu kuvamile ukuthi kungenxa yokuthi imithi iyasebenza, hhayi ngoba awusayidingi.

Abanye abantu bayazibuza ukuthi bangayeka yini imithi yabo yesifo sikashukela ngemuva kokunciphisa umzimba noma ukwenza izinguquko ezinkulu zokuphila. Ngenkathi lezi zithuthukiso zinhle futhi zinganciphisa izidingo zakho zemithi, isinqumo sokuyeka noma ukunciphisa imithi yesifo sikashukela kufanele senziwe ngaso sonke isikhathi ngaphansi kokugadwa kwezokwelapha.

Udktora wakho uzocabangela izinto eziningi lapho enquma ukuthi ungakwazi yini ukunciphisa ngokuphepha noma ukuyeka i-sitagliptin, okuhlanganisa amazinga akho akamuva e-A1C, impilo yonke, eminye imithi oyithathayo, nokuthi sekuyisikhathi esingakanani unesifo sikashukela. Bangase batusa ukunciphisa kancane kancane esikhundleni sokuyeka ngokuphelele.

Uma unesithakazelo sokunciphisa imithi yakho yesifo sikashukela, gxila ekugcineni izinguquko zokuphila ezinempilo eziye zathuthukisa ukulawulwa kukashukela wakho wegazi. Qhubeka usebenza nethimba lakho lokunakekelwa kwezempilo ukuze uqaphele intuthuko yakho futhi wenze izinguquko zemithi ngokuphepha uma kufanelekile.

Ngingayithatha i-Sitagliptin neminye imithi?

I-Sitagliptin ngokuvamile isebenza kahle kakhulu neminye imithi, kodwa kubalulekile ukutshela umhlinzeki wakho wokunakekelwa kwezempilo ngakho konke okuthathayo, okuhlanganisa imithi kadokotela, imithi etholakala ngaphandle kwe-oda, amavithamini, kanye nezithasiselo zemithi yezitshalo.

Eminye imithi ingathinta ukuthi i-sitagliptin isebenza kahle kangakanani noma ikhulise ingozi yakho yemiphumela emibi. Isibonelo, ama-antibiotics athile kanye nemithi elwa nesikhunta ingashintsha indlela umzimba wakho oqhubula ngayo i-sitagliptin, nakuba lezi zinto ezihlangene zivame ukulawuleka ngokulungiswa komthamo.

Uma uthatha eminye imithi yesifo sikashukela kanye ne-sitagliptin, udokotela wakho uzokuqapha eduze ukuze uthole izigameko zikashukela ophansi. Ngenkathi i-sitagliptin yodwa ingavamile ukubangela i-hypoglycemia, ukuhlanganiswa neminye imithi yesifo sikashukela kungakhuphula le ngozi.

Njalo yazisa noma yibaphi abahlinzeki bezempilo abasha ukuthi uthatha i-sitagliptin, okuhlanganisa odokotela bamazinyo, ochwepheshe, kanye nodokotela begumbi eliphuthumayo. Lokhu kusiza ukuqinisekisa ukuthi bangakwazi ukunquma eminye imithi ngokuphepha futhi bagweme ukuxhumana okungase kuthinte ukuphathwa kwesifo sakho sikashukela.