He aha te Desmopressin: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

Ko te Desmopressin he rongoā taiaki waihanga e āwhina ana i tō tinana ki te whakahaere i te tauritenga wai me te whakahaere i te hanga mimi. Whakaarohia he whakakapinga whai hua mō te taiaki tūturu e kīia nei ko te vasopressin (e mōhiotia ana hoki ko te taiaki antidiuretic, ADH rānei) tē pea e nui ana te hanga e tō tinana.

E mahi ana tēnei rongoā mā te kī atu ki ō tākihi kia mau tonu te wai, kaua e tuku kia puta mā te mimi. He mea whakahau pinepine mō ngā āhuatanga pēnei i te mate huka insipidus, te mōmiti i ngā tamariki, me ētahi mate toto e hiahia ana tō tinana i te āwhina anō ki te whakahaere i ngā wai, i te pūmua toto rānei.

He aha te Desmopressin e whakamahia ana mō?

E rongoā ana te Desmopressin i ētahi āhuatanga e pā ana ki te kore tauritenga taiaki me te whakahaere wai i tō tinana. Ko te whakamahinga tino noa mō te mate huka insipidus, he āhuatanga kāore e nui te hanga o te taiaki antidiuretic tūturu e tō tinana, e hua ai te mimi nui me te tino matewai.

Tērā pea ka whakahau tō tākuta i te desmopressin mēnā kei te raru koe i te mōmiti i te pō (nocturnal enuresis), inā rā i ngā tamariki neke atu i te 6 tau te pakeke. Ka taea e ia te whakaiti i te maha o ngā pō mākū mā te āwhina i ngā tākihi ki te whakakoi i te mimi i te wā e moe ana.

Mō ngā tāngata e pā ana ki ētahi mate toto pēnei i te hemophilia A ngawari, i te mate von Willebrand rānei, ka taea e te desmopressin te āwhina i te whakapai ake i te pūmua toto i mua i ngā pokanga, i ngā mahi niho rānei. E mahi ana mā te whakanui i ngā taumata o ngā mea pūmua toto i roto i tō toto.

I te nuinga o te wā, ka whakahau ngā tākuta i te desmopressin mō te whakahaere i te mimi nui i te pō i ngā pakeke (nocturia) i te wā kāore anō ētahi atu rongoā i pai te mahi. Ka taea e tēnei te whai hua mō ngā tāngata e raruraru ana te moe i ngā haerenga ki te wharepaku.

Me pēhea te mahi a te Desmopressin?

Ka mahi a Desmopressin mā te whai i te homoni antidiuretic tūturu o tō tinana, he rite te mahi ki te karere e kōrero ana ki ō tākihi he aha te mahi ki te wai. Ka tango koe i tēnei rongoā, ka herea ki ngā kaiwhakawhiwhi motuhake i ō tākihi, ka kōrero ki a rātou kia hoki anō te wai ki roto i ō toto, kaua e waiho hei mimi.

Na tēnei tukanga ka kaha ake tō mimi, ka whakaiti i te nui katoa e whakaputaina ana e koe. E kiia ana he rongoā kaha ngawari nā te mea e pā tika ana ki ngā ara homoni e whakahaere ana i ngā mahi nui o te tinana pēnei i te taurite wai.

Ka mahi hoki te rongoā ki ngā oko toto, ā, ka taea te whakanui i ētahi mea whakaheke toto i roto i ō toto. Na tēnei mahi rua ka whai hua mō ngā raruraru whakahaere wai me ngā mate whakaheke toto ngawari.

Kāore i rite ki ētahi rongoā e mahi ana puta noa i tō tinana katoa, ka aro a desmopressin ki ngā kaiwhakawhiwhi motuhake, e āwhina ana ki te whakaiti i ngā pānga e kore e hiahiatia ki ētahi atu pūnaha tinana. Ko te tikanga ka roa ngā pānga mō te 8-12 haora i runga i te horopeta me tō urupare takitahi.

Me pēhea taku tango i te Desmopressin?

Tangohia te desmopressin kia rite ki te tohutohu a tō tākuta, te tikanga kotahi, e rua rānei i te rā i runga i tō āhua. Ka taea te tango i ngā papa waha me te kore kai, engari ko te tango i ngā wā kotahi i ia rā ka āwhina i te pupuri i ngā taumata pūmau i roto i tō pūnaha.

Ka taea e koe te tango i te rongoā me te wai, ā, kāore he take ki te karo i te miraka, i ētahi atu inu rānei, ki te kore tō tākuta e tohutohu motuhake ana. Heoi, he mea nui kia whai i ngā tohutohu a tō tākuta mō te inu wai, nā te mea ko te inu nui rawa atu i te wai i te wā e tango ana i te desmopressin ka hua te pupuri wai.

Mō te mimi i te moenga, te tikanga ka tūtohu ngā tākuta kia tangohia te horopeta tata ki te 1 haora i mua i te moe i runga i te puku kau. Mā tēnei wā ka āwhina te rongoā kia whai hua i ngā haora moe ina hiahia koe ki te kukume mimi nui.

Mēnā kei te tango koe i te desmopressin mō te mate huka insipidus, tērā pea ka hiahia koe ki te tango i te rongoā nei i ngā wā maha i te rā kia mau tonu ai te tauritenga wai. Ka tīmata pea tō tākuta ki te horopeta iti, ā, ka whakatika i runga i te pai o tō urupare me ngā pānga taha ka pā ki a koe.

Kia Pēhea te Roa e Tango Ana ahau i te Desmopressin?

He rerekē te roa o te maimoatanga desmopressin i runga i tō āhuatanga motuhake me te urupare takitahi. Mō te mate huka insipidus, tērā pea ka hiahia koe ki te maimoatanga wā-roa mai i te mea e hiahia ana tēnei āhuatanga ki te whakakapi hormone tonu kia mau tonu ai te tauritenga wai tika.

Mēnā kei te whakamahi koe i te desmopressin mō te mimi i te moenga, ko te maimoatanga te nuinga o te wā e 3-6 marama i te tīmatanga, me ngā okiokinga auau kia kite ai mehemea ka whakatau noa te raruraru. He maha ngā tamariki ka mutu pea te rongoā i te wā e pakeke ana rātou, ā, ka whakawhanake i te mana whakahaere pūpū i te pō.

Mō ngā mate toto, tērā pea ka hiahia koe ki te desmopressin mō te wā poto i mua i ngā mahi pokanga, i ngā mahi niho rānei. I ēnei keehi, tērā pea ka roa te maimoatanga i ngā rā torutoru i te wā o tō mahi.

Ka aroturuki auau tō tākuta i tō urupare, ā, ka tūtohu pea i ngā okiokinga wā-wā mai i te rongoā kia arotake ai mehemea kei te hiahia tonu koe. Kaua rawa e mutu te tango i te desmopressin ohorere ana me te kore tohutohu hauora, ina koa mēnā he mate huka insipidus tō, nā te mea ka puta tēnei ki te matewai kino.

He Aha ngā Pānga Taha o te Desmopressin?

Pērā i ngā rongoā katoa, ka taea e te desmopressin te pānga taha, ahakoa he maha ngā tāngata e pai ana ki te tango i te rongoā nei i te wā e tohua ana. Ko te pānga taha tino mōrearea ko te pupuri wai, ka puta ki te taumata konutai iti i roto i tō toto (hyponatremia) mēnā ka inu koe i te wai nui rawa i te wā e tango ana i te rongoā.

Ngā pānga taha noa ka pā ki a koe ko te ānini, te whakapairuaki, te mamae puku, me te whanoke ngawari. Ko ēnei tohu ka pai ake i te wā e urutau ana tō tinana ki te rongoā, te nuinga o te wā i roto i ngā wiki tuatahi o te maimoatanga.

Koinei nga paanga taha e tino kitea ana e tika ana kia mohio koe:

• Te ānini me te whanoke ngawari
• Te whakapairuaki, te puku ranei
• Te pupuhi i te ihu, te ihu ranei e rere ana
• Te whero, te mahana ranei o te kanohi
• Te ngenge ngawari, te ngoikore ranei

Ko enei paanga noa karekau e tika kia whakamutua te rongoa mena ka raru, ka whakararu ranei i o mahi o ia ra.

He iti noa nga paanga kino, engari me tere te rongoa. Ka puta te waipiro wai mena ka inu koe i te nui o te wai i te wa e tango ana koe i te desmopressin, ka puta nga tohu penei i te ānini nui, te rangirua, te hopu, te uaua ranei ki te manawa.

Kia mataara ki enei tohu whakatūpato e hiahia ana kia tere te rongoa:

• Te ānini nui me te rangirua, te kore ranei e mohio
• Te kōpiko uaua, te ngoikore ranei
• Te hopu, te wiri ranei
• Te uaua ki te manawa, te mamae ranei o te uma
• Te whakapairuaki nui me te ruaki
• Te pikinga tere o te taumaha, te pupuhi ranei

Mena ka pa ki a koe etahi o enei tohu kino, whakapā atu ki to kaiwhakarato hauora tonu, rapu ranei i te rongoa ohorere.

Ka pa pea etahi tangata i nga tauhohenga mate pāwera ki te desmopressin, ahakoa he onge tenei. Ko nga tohu ko te ponana kiri, te mānukanuka, te pupuhi o te kanohi, te korokoro ranei, te uaua ranei ki te manawa. Ko nga tauhohenga mate pāwera katoa e hiahia ana kia tere te rongoa.

Ko wai e kore e tango i te Desmopressin?

Me karo etahi tangata i te desmopressin na te nui o te tupono o nga raruraru nui. Kaua koe e tango i tenei rongoa mena he iti te konutai i roto i to toto (hyponatremia) mena he mate whatukuhu ranei e pa ana ki to kaha ki te tukatuka wai.

Ko nga tangata e mate ana i te ngakau, etahi atu ranei e pupuri ana i te wai me karo i te desmopressin, na te mea ka kino ake te pupuhi me te taumahatanga o te ngakau. Ka ata tirotirohia e to taakuta to hauora ngakau i mua i te whakahau i tenei rongoa.

Mēnā he toto tiketike kāore i te whakahaeretia e koe, tērā pea ka tūtohu tō tākuta kia kaua e whakamahi i te desmopressin nā te mea ka pā ki te mahi o ngā oko toto. Waihoki, ko ngā tāngata e pā ana ki ētahi momo mate pūhui toto, ki te hunga rānei e tango ana i ngā rongoā whakaheke toto, me whai whakaaro motuhake.

Me tūpato anō ngā kaumātua i te wā e tango ana i te desmopressin nā te mea he māmā ake te whanaketanga o te taumata konutai iti me te pupuri wai. Tērā pea ka tīmata tō tākuta ki ngā horopeta iti ake, ā, ka mātakitaki tata atu i a koe mēnā kei runga ake koe i te 65 tau.

Me kōrero ngā wāhine hapū me ngā wāhine e whāngai ana i ngā pēpi ki ngā tūponotanga me ngā painga ki tō rātou kaiwhakarato hauora, nā te mea ka taea e te rongoā te whakawhiti i te pūreirei me te uru ki te waiu u. Ahakoa i ētahi wā ka whakamahia i te wā e hapū ana, he mea nui te mātakitaki tupato.

Ngā Ingoa Waitohu o Desmopressin

E wātea ana te Desmopressin i raro i ētahi ingoa waitohu, ko DDAVP te mea e mōhiotia whānuitia ana. Ka whakamahia tēnei ingoa waitohu mō ngā papa waha me ngā pū rehu ihu o te rongoā.

Ko ētahi atu ingoa waitohu ko Minirin, e wātea ana i ētahi whenua, me Nocdurna, i hangaia motuhake mō te rongoā i te mimi i te pō i ngā pakeke. Tērā pea ka mau i tō whare rongoā ngā putanga whānui o te desmopressin, kei roto nei te whakauru kaha kotahi engari he iti ake te utu i ngā putanga ingoa waitohu.

Ko te waitohu motuhake, te putanga whānui rānei ka whiwhi koe, tērā pea ka rerekē i runga i te inihua e hipoki ana i a koe me ngā hiahia o te whare rongoā. Ko ngā putanga katoa o te desmopressin kua whakaaetia, he rite te mahi, engari tērā pea ka rerekē ngā whakauru kore kaha i waenga i ngā kaihanga.

Ngā Kōwhiringa kē mō Desmopressin

He maha ngā kōwhiringa kē mō te desmopressin i runga i tō āhuatanga motuhake me ngā whāinga maimoatanga. Mō te mate huka insipidus, ko ētahi atu kōwhiringa maimoatanga ko ngā thiazide diuretics, he rerekē te mahi mā te whakanui ake i te tairongo o ō tākihi ki te homoni tūturu e whakaputaina tonutia ana e koe.

Mō te mimi i te moenga i ngā tamariki, ko ngā huarahi whanonga pēnei i te whakangungu pūpū, ngā pūoho makuku, me ngā wā whakatā ki te wharepaku i whakaritea he huarahi kē e whai hua ana. E tūtohu ana ētahi tākuta kia whakamātau i ēnei tikanga i mua i te rongoā, i te taha rānei o te rongoā.

Mēnā kei te raru koe i te mimi i te pō, ko ngā whakarerekētanga o te oranga pēnei i te whakaiti i te inu wai i mua i te moe, te karo i te kawhe me te waipiro, me te rongoā i ngā mate moe e huna ana, ka āwhina pea ki te whakaiti i ngā tohu.

Mō ngā mate toto, ko ngā huarahi kē ko ētahi atu pūhui take whakaheke toto, rānei rongoā pēnei i te waikawa tranexamic, e āwhina ana ki te ārai i te pakaru o ngā toto. Ka taea e tō tākuta toto te kōrero mō te kōwhiringa e pai ana mō tō momo mate toto.

He Pai Anei te Desmopressin i te Vasopressin?

He maha ngā painga o te Desmopressin i te vasopressin tūturu mō te nuinga o ngā whakamahinga rongoā. Ka roa ake te noho i roto i tō pūnaha (8-12 haora i te whakataurite ki te 10-20 meneti o te vasopressin), ko te tikanga he iti ake ngā horopeta e hiahiatia ana e koe i te rā.

Kāore i rite ki te vasopressin, he iti noa iho ngā pānga o te desmopressin ki te pēhanga toto me te tere o te ngākau, e noho haumaru ana mō ngā tāngata e pā ana ki ngā mate ngākau. Ko tēnei mahi whiriwhiri ko te tikanga ka whiwhi koe i ngā painga o te whakapai ake i te pupuri wai me te kore ngā pānga i te toto e hiahiatia ana.

Ka tae mai hoki te desmopressin i roto i te puka papa waha e watea ana, i te mea me werohia te vasopressin. Mā tēnei ka māmā ake te whakamahi i te desmopressin mō te rongoā wā roa, ina koa mō ngā āhuatanga pēnei i te mate huka insipidus, te mimi i te moenga rānei.

Heoi anō, ka pai pea te vasopressin i ngā wā ohorere e hiahiatia ana te tīmatanga tere, pēnei i ētahi momo ohorere, te toto nui rānei. Ka whiriwhiria e tō tākuta te rongoā e tika ana i runga i ō hiahia rongoā me ō āhuatanga.

Ngā Pātai Auau mō te Desmopressin

He Haumaru te Desmopressin mō te Mate Huka?

Āe, he pai te desmopressin mō te hunga mate huka (diabetes mellitus), nā te mea kāore e pā ana ki ngā taumata huka toto. Heoi anō, he mea nui kia wehewehe i waenga i te diabetes mellitus me te diabetes insipidus, nā te mea he rerekē rawa ēnei āhuatanga ahakoa he ingoa rite ō rāua.

Mēnā he diabetes mellitus tō, ā, e hiahia ana koe ki te desmopressin mō te diabetes insipidus, mō tētahi atu āhuatanga rānei, ka āta tirotiro tō tākuta i a koe. Kāore ngā pānga o te desmopressin ki te pupuri wai e whakararu i ngā rongoā diabetes pērā i te insulin, i te metformin rānei.

Ko te hunga mate huka e tango ana i te desmopressin me pupuri i tā rātou mahinga tirotiro huka toto, me te pūrongo i ngā tohumate rerekē ki tō rātou kaiwhakarato hauora i te wā tonu.

Me Pēhea Taku Mahi Mēnā Ka Whakamahia E Au Te Nui Rawa O Te Desmopressin?

Mēnā ka tango koe i te nui rawa o te desmopressin i te mea i whakaritea, whakapā atu ki tō tākuta, ki te pūtau whakahaere paitini rānei i te wā tonu. Ko te tango i te nui rawa ka arahi ki te pupuri wai mōrearea me ngā taumata konutai iti rawa i roto i tō toto.

Kaua e inu i te nui o te wai, i ētahi atu wai rānei mēnā kua tango koe i te nui rawa, nā te mea ka kino ake tēnei raruraru. Engari, whakawhāiti i tō inu wai, ā, rapua te āwhina hauora i te wā tonu.

Ngā tohu o te nui rawa o te rongoā ko te mamae nui o te upoko, te rangirua, te whakapairuaki, te ruaki, me te ngoikore o ngā uaua. Mēnā ka pā mai te hauhautanga, te uaua ki te manawa, te ngaro rānei o te māramatanga, waea atu ki ngā ratonga ohorere i te wā tonu.

Me Pēhea Taku Mahi Mēnā Ka Ngaro I Au Tētahi Inenga Desmopressin?

Mēnā ka ngaro i a koe tētahi inenga desmopressin, tangohia i te wā e mahara ana koe, ki te kore e tata ana te wā mō tō inenga e whai ake nei. I tērā take, waiho te inenga i ngaro, ā, haere tonu ki tāu mahinga inenga.

Kaua rawa e tango i ngā inenga e rua i te wā kotahi hei utu mō tētahi inenga i ngaro, nā te mea ka piki ake tō tūponotanga ki ngā pānga taha. Mēnā he maha ngā wā e wareware ana koe ki ngā inenga, whakaarohia te whakatakoto i ngā whakamaharatanga waea, te whakamahi rānei i tētahi kaiwhakarite pire hei āwhina i a koe kia noho i runga i te ara.

Mō te rongoā mō te mimi i te moenga, ki te ngaro koe i te horopeta i te ahiahi, ka taea e koe te tango i mua i te moenga i te mea kāore anō i te pōrohe. Heoi, kaua e tango i te mea kua moe kē koe, nā te mea ka raru pea tō wā moe.

Āhea ka taea e au te whakamutu i te tango Desmopressin?

Ko te whakatau ki te whakamutu i te desmopressin e whakawhirinaki ana ki tō āhuatanga o raro, me mahi tonu me te tohutohu a tō tākuta. Mō te mate huka insipidus, ka hiahia pea koe ki te rongoā mō te roanga o te ora, engari ko te mimi i te moenga ka ngaro noa iho i te wā e tipu ana ngā tamariki.

Ka hiahia pea tō tākuta ki te mahi i ngā whakamātau i waho o te rongoā i ia wā ki te kite mena kua pai ake, kua ngaro rānei tō āhuatanga. Ko ēnei "hararei rongoā" ka āwhina ki te whakatau mena kei te hiahia tonu koe ki te rongoā.

Kaua rawa e whakamutu i te tango desmopressin ohorere, me te kore e tirotirohia e te tākuta, ina koa kei a koe te mate huka insipidus, nā te mea ka puta te waiwai tere me ngā taurite hiko kino.

Ka taea e au te inu waipiro i te wā e tango ana i te Desmopressin?

Me whakawhāiti koe i te inu waipiro i te wā e tango ana i te desmopressin, nā te mea ka taea e te waipiro te whakararu i te whai huatanga o te rongoā me te whakanui i tō tūponotanga ki ngā pānga taha. Ka pā te waipiro ki te taurite hormone tūturu o tō tinana, ā, ka uaua ake te mahi a te desmopressin.

Ko te inu waipiro ka whakanui hoki i tō tūponotanga ki te waiwai, ki te kore rānei, ka nui ake te tūponotanga ki te inu i te wai nui, e rua nei ka raru i te wā e tango ana i te desmopressin.

Mēnā ka whiriwhiri koe ki te inu waipiro i ētahi wā, me mahi i roto i te āhua tika, me te tino tupato ki te aroturuki i tō inu wai. Kōrerohia tō inu waipiro ki tō tākuta kia mōhio ai e kore e whakararu i ō whāinga rongoā.