He aha te Desmopressin Sublingual: Ngā Whakamahinga, te Inenga, Ngā Pānga Taha me Ētahi Atu

Ko te Desmopressin sublingual he rongoā taiaki waihanga ka whakatakotoria e koe ki raro i tō arero hei rongoā i ngā āhuatanga kāore e nui te hanga o te antidiuretic hormone (ADH) e tō tinana. Ka rewa wawe tēnei papa iti, ā, ka āwhina i ō tākihi ki te pupuri wai kia whai hua ake, e whakaiti ana i te mimi nui me te matewai.

Ko te ara sublingual te tikanga ka ngongo tika te rongoā mā ngā kiko i raro i tō arero ki roto i ō toto. He tere ake tēnei tikanga i te horomia i ngā pire, ā, he tino whai hua pea ina hiahia koe ki te āwhina tere mai i ngā tohumate, kei te raru rānei koe ki te pupuri i ngā rongoā waha.

He aha te Desmopressin?

Ko te Desmopressin he putanga i hangaia e te tangata o te vasopressin, he homoni e hangaia ana e tō roro hei āwhina i te whakahaere i te taurite wai i tō tinana. Ina iti, kāore rānei e mahi tika ana ngā taumata homoni tūturu o tō tinana, ka uru mai te desmopressin ki te mahi i taua mahi.

Whakaarohia te vasopressin hei kaiwhakahaere tiaki wai o tō tinana. E kī ana ki ō tākihi me pupuri wai i te wā, me tuku atu i te wā hei mimi. Ki te kore e nui tēnei homoni, ka tuku rawa ō tākihi i te wai, ka waiho koe i te matewai tonu me te oma ki te wharepaku.

E whakahere ana te puka sublingual i tētahi huarahi pai kē atu i ngā rehu ihu, i ngā werohanga rānei. He maha ngā tāngata e kite ana he māmā ake te whakamahi me te pono ake, ina koa kei a rātou te pūhihu ihu, ētahi atu raru rānei ka raru pea i te ngongo ihu.

He aha te Desmopressin e whakamahia ana?

Ko te Desmopressin sublingual te mea nui e rongoā ana i te diabetes insipidus, he āhuatanga kāore e taea e tō tinana te whakahaere tika i te taurite wai. Kāore i rite ki te diabetes mellitus (te momo noa ake), kāore he pānga o te diabetes insipidus ki ngā taumata huka toto.

Ka āwhina hoki te rongoā ki te whakahaere i te mimi i te moenga i ngā tamariki me ngā pakeke i te wā kāore anō ētahi atu rongoā i whai hua. Ka whakaiti i te hanga mimi i te wā e moe ana, e whai wāhi ana te pūpū ki te pupuri i te wai nui ake i te pō.

Ka tohua pea e tō tākuta te desmopressin mō ētahi āhuatanga motuhake, e hiahia ana ia ki te aroturuki tupato:

• Te mate huka insipidus matua, i te wā kāore anō tō roro i te hanga i te vasopressin nui
• Nocturnal enuresis (mimi i te moenga) i ngā tamariki neke atu i te 6 tau te pakeke
• Nocturia, e pā ana ki te mimi auau i te pō i ngā pakeke
• Te mate huka insipidus rangitahi i muri i te pokanga roro, i te wharanga roro rānei
• Ētahi mate toto e āwhina ana ki te tuku i ngā mea whakaheke toto

E hiahia ana ia āhuatanga ki ngā huarahi rerekē mō te horopeta me te aroturuki. Mā tō kaiwhakarato hauora e whakatau te whakamahi tino tika i runga i ō tohu motuhake me te hītori hauora.

Me pēhea te mahi a Desmopressin?

Ka mahi a Desmopressin mā te whai i te homoni antidiuretic tūturu o tō tinana, ka herea ki ngā kaiwhakawhiwhi motuhake i ō tākihi. E kī ana tēnei mahi ki ō tākihi kia hoki mai te wai nui ake i tō mimi, ka whakakaha i te wai, ka whakaiti i te nui katoa e hangaia ana e koe.

E whakaarohia ana te rongoā he kaha ngawari, he tino whai hua mō ōna whakamahinga. I te wā e mahi tika ana, ka taea e ia te whakaiti i te whakaputa mimi mā te 50-90% i roto i ētahi haora i muri i te tango.

Ka rewa ngā papa sublingual i raro i tō arero i roto i te 2-3 meneti, me te pānga e tīmata ana i roto i te 15-30 meneti. Ko te tino whai huatanga ka puta i roto i te 1-2 haora, ā, ka taea te roa 8-12 haora, i runga i tō urupare takitahi me te horopeta.

Kāore i rite ki ētahi rongoā e mahi ana puta noa i tō tinana katoa, ko te desmopressin te mea matua e whai ana i ō tākihi me ngā oko toto. E āwhina ana tēnei mahi arotahi ki te whakaiti i ngā pānga taha i te wā e whakanui ana i ngā painga rongoā mō te whakahaere wai.

Me pēhea taku tango i te Desmopressin?

Me tango ngā papa desmopressin sublingual mā te whakatakoto i raro i tō arero, kia rewa katoa. Kaua e ngaungau, e kuru, e horomia rānei ngā papa katoa, nā te mea ka whakaiti i tō rātou whai huatanga.

Me tango koe i te rongoā i runga i te puku kau, i te iti rawa 1 haora i mua i te kai, i te 2 haora rānei i muri i te kai. Ka taea e te kai te whakararu i te urunga mai i roto i ngā kiko i raro i tō arero, ka kore e whai hua te rongoā.

Anei me pēhea te tango tika i tō desmopressin sublingual:

1. Horoi tino pai ō ringaringa i mua i te hapai i te papa
2. Tangohia te papa i tōna pōkai i mua tonu i te whakamahi
3. Whakatakotoria te papa i raro i tō arero, ki muri
4. Kia katia tō waha, me te karo i te kōrero i te wā e rewa ana
5. Kaua e kai, e inu, e horoi rānei i tō waha mō te 15 meneti i muri i te tango
6. Kaua e paowa, e whakamahi rānei i ngā hua tupeka i te wā e tango ana koe

He mea nui te wā o ō horopeta. Ko te nuinga o te tangata e tango ana i te desmopressin i te ahiahi mō te mōmiti i te moenga, i ngā raruraru mimi i te pō, i te wā e hiahia ana te hunga e mate huka insipidus i ngā horopeta maha i te rā.

Kia Pēhea te Roa e Tango Ana ahau i te Desmopressin?

Ko te roa o te maimoatanga desmopressin e whakawhirinaki ana ki tō āhuatanga o raro, me te pai o tō urupare ki te rongoā. E hiahia ana ētahi tāngata mō ētahi marama, i te wā e hiahia ana ētahi atu ki te maimoatanga wā roa.

Mō te mōmiti i te moenga, te maimoatanga te tikanga ka roa 3-6 marama i te tīmatanga, me ngā wā okioki kia kite ai mehemea kua ngaro noa te raruraru. He maha ngā tamariki e tipu ana i te mōmiti i te moenga, nō reira ka pai ngā tākuta ki te arotake i ngā wā katoa, kaua ki te haere tonu mō ake tonu atu.

Ko te hunga e mate huka insipidus tūturu, ka hiahia pea ki te maimoatanga mō te oranga katoa, engari kāore tēnei e kī ana i te horopeta kotahi mō ake tonu atu. Ka whakatika tō tākuta i tō horopeta i runga i ō tohumate, ngā hua taiwhanga, me ētahi huringa i tō āhua hauora.

Ka whakarite tō tākuta hauora i ngā tūponotanga whai muri hei aroturuki i tō urupare me te mātakitaki i ngā raruraru. Kaua rawa e mutu ohorere te tango desmopressin me te kore tohutohu hauora, nā te mea ka hoki wawe mai ō tohu, ā, ka kaha rawa atu.

He aha ngā pānga taha o te Desmopressin?

He pai te whakamanawanui a te nuinga o te tangata ki te desmopressin, engari pērā i ngā rongoā katoa, ka pānga taha mai i te ngawari ki te kaha. Ko ngā pānga taha e tino kitea ana, he mea whakahaere noa, ā, he maha ngā wā ka pai ake i te wā e urutau ana tō tinana ki te rongoā.

Ngā pānga taha noa e pā ana ki te nuinga o te tangata:

• Te ānini, te whanoke rānei
• Te whakapairuaki, te mamae puku rānei
• Te pōrearea ihu, te ihu wai rānei
• Te whero o te kiri, te whero o te kanohi rānei
• Te ngenge ngawari, te moe rānei
• Te waha maroke, te reka rerekē rānei

Ko ēnei pānga taha o ia rā, ka ngaro i roto i ngā rā, i ngā wiki rānei i te wā e urutau ana tō tinana ki te rongoā. Mā te noho wai, me te tango i te rongoā i te ara i tohutohutia, ka āwhina i te whakaiti i ēnei pānga.

Ko ngā pānga taha kaha ake, me tono wawe te āwhina hauora, tae atu ki te paitini wai, e pā ana ki te wā e pupuri ana tō tinana i te nui rawa o te wai:

• Te ānini kaha me te raruraru, te rerekē rānei o te hinengaro
• Ngā pākia, ngā kōpiko uaua rānei
• Te whakapairuaki kaha me te ruaki
• Te pikinga tere o te taumaha mai i te pupuri wai
• Te pūhi i ngā ringa, ngā waewae, te kanohi rānei
• Te uaua ki te hā, te pōkae rānei o te uma

Ko te paitini wai te raruraru tino mōrearea, ahakoa he mea onge i te wā e whakamahia tika ana te rongoā. E pā ana tēnei i te wā e mahi pai rawa ana te desmopressin, e pā ana ki tō tinana ki te pupuri i te nui rawa o te wai.

Ko wai kāore e tika ana kia tango Desmopressin?

Me karo ētahi tāngata i te desmopressin nā te mea ka kino ake pea ō rātou āhuatanga hauora o nāianei, ka pā rānei ki ētahi atu rongoā. Ka āta arotake tō tākuta i tō hītori hauora i mua i te whakahau i tēnei rongoā.

Kaua koe e tango desmopressin mēnā he mate tākihi tō, he ngoikore te ngākau, he hītori rānei o te iti o te konutai i roto i ō toto. Ka piki ake ēnei āhuatanga i tō tūponotanga ki te pupuri wai me te kore taurite o te hiko.

He maha ngā āhuatanga hauora ka kore pea e haumaru te desmopressin:

• Te mate ngākau nui, te pēhanga toto tiketike rānei kāore i te whakahaerehia
• Te mate tākihi, te iti rānei o te mahi tākihi
• He hītori o te hopu, o ngā mate roro rānei
• Psychogenic polydipsia (te inu wai kaha)
• Te maroke nui, te kore taurite rānei o te hiko
• Ētahi momo mate pūkahukahu

He mea nui hoki ngā whakaaro e pā ana ki te pakeke. He nui ake te tūponotanga o ngā kaumātua ki ngā raruraru, ina koa te pupuri wai me te iti o te konutai, nō reira me āta aroturuki, ā, he iti ake te horopeta.

Me whai whakaaro motuhake ngā wahine hapū me te whāngai u, ahakoa ka whakamahia i ētahi wā te desmopressin i te wā e hapū ana mō te mate huka insipidus. Ka whakataurite tō tākuta i ngā painga ki ngā tūponotanga pea mō te whaea me te pēpi.

Ngā Ingoa Waitohu Desmopressin

Ko te ingoa waitohu tino noa mō te desmopressin sublingual ko Nocdurna, e whakaaetia ana mō te mimi i te pō i roto i ngā pakeke. I hangaia tēnei whakahāteanga kia mahi i te pō, kia mutu i te ata.

Ko ētahi atu ingoa waitohu ko Minirin me DDAVP, ahakoa he nui ake te wātea o ēnei hei rehu ihu, hei papa rānei ka horomia e koe. He hou ake te puka sublingual, ā, he iti ake te wātea i ētahi atu whakahāteanga.

Kei te wātea ngā momo rongoā rāpoi o te desmopressin i raro i te arero, ā, ka taea te whakaiti i ngā utu. Heoi, me whakamahi tonu koe i te waitohu kotahi, i te momo rongoā rāpoi rānei, nā te mea he rerekē pea te tere o te ngongo o ngā momo rongoā.

Me hoatu e tō whare rongoā te waitohu kotahi ki a koe i ia wā, ki te kore koe e tono kia huri. Ki te hiahia koe ki te huri i ngā waitohu, tērā pea ka hiahia tō tākuta ki te mātakitaki i a koe kia mōhio ai kei te whai hua te momo rongoā hou.

Ngā Kōwhiringa kē mō te Desmopressin

He maha ngā kōwhiringa kē mō te desmopressin, i runga i tō āhuatanga motuhake me te take e hiahia ana koe ki te rongoā. Ko te kōwhiringa kē pai rawa atu kei runga i ō tohumate, te hītori hauora, me te pai o tō urupare ki ētahi atu rongoā.

Mō te mimi i te moenga, ko ngā kōwhiringa kē ko ngā pūoho mimi i te moenga, ngā mahi whakangungu pūpū, me ngā whakarerekētanga o te oranga pēnei i te whakaiti i te wai i te pō. He pai te rongoā antidepressant tricyclic pēnei i te imipramine mō ētahi tāngata, ahakoa he rerekē ngā pānga taha.

He iti noa iho ngā kōwhiringa kē mō ngā tāngata e mate huka insipidus, engari ko ngā kōwhiringa ko:

• Ngā rongoā diuretic thiazide, e āwhina ana i te pupuri wai i ētahi wā
• Chlorpropamide, he rongoā mate huka tawhito e taea te whakanui i te tairongo vasopressin
• Carbamazepine, he rongoā anti-seizure e āwhina ana i ētahi wā mō ngā keehi ngawari
• Te whakanui i te inu wai me ngā whakarerekētanga kai

Mō te mimi i te pō, ko ngā kōwhiringa kē ko te rongoā i ngā āhuatanga e huna ana pēnei i te moe apnea, te whakatika i ngā rongoā e whakanui ana i te hanga mimi, me te whakamahi i ngā tikanga whanonga pēnei i te whakawātea i te wā.

Ka whakaaro tō tākuta ki tō āhuatanga takitahi, tae atu ki ētahi atu rongoā e tango ana koe, tō tau, me tō āhua hauora whānui i te wā e tūtohu ana i ngā kōwhiringa kē.

He Pai Anei te Desmopressin i te DDAVP?

He rite tonu te rongoā a DDAVP me te desmopressin, he rerekē noa ngā āhua. Ko te DDAVP he ingoa waitohu e wātea ana hei rehu ihu, ā, ko te desmopressin sublingual ka puta mai i ngā papa e rewa ana i raro i tō arero.

He pai ake te āhua sublingual i te DDAVP ihu, mō te hunga e raru ana ki ngā rehu ihu. Ki te whai koe i te pōrearea ihu tonu, i ngā mate pāwera, i te makariri auau rānei, ka pai ake te mahi a ngā papa sublingual.

Mā te whakatairite i ngā tikanga tuku e rua ka kitea ngā rerekētanga nui:

• Ka nui ake te horopeta o ngā papa sublingual i ngā rehu ihu
• He tere ake te mahi a ngā rehu ihu engari ka pā mai te pōrearea
• He māmā ake te whakamahi i ngā papa sublingual mō te hunga e raru ana ki te mōhiotanga
• Ka nui ake te riri o te rohe me te pūhi ihu i ngā rehu ihu
• He pai ake pea ngā papa sublingual mō te haere

He rite tonu te whai hua i waenga i ngā āhua e rua ina whakamahia tika ana. Ko te whiriwhiri i waenga i a rāua e pā ana ki te hiahia whaiaro, ngā raruraru ihu e pā ana ki a koe, me te āhua e pai ake ana te inihua.

E kite ana ētahi tāngata he pai ake te urupare ki tētahi āhua i tētahi atu, ahakoa kei roto i a rāua te whakauru kaha kotahi. Ka taea e tō tākuta te āwhina i a koe ki te whakatau ko tēhea kōwhiringa e pai ana mō tō āhuatanga motuhake.

Ngā Pātai Auau mō te Desmopressin

He Haumaru te Desmopressin mō te Mate Ngākau?

Me tūpato te hunga e mate ngākau ana ina tango desmopressin nā te mea ka puta te pupuri wai me te pā ki te pēhanga toto. Me mahi tahi tō kaimātai ngākau me te tākuta whakahau kia whakatau mehemea he haumaru mōu.

Ki te whai koe i te mate ngākau ngawari, i te mate ngākau e whakahaerehia ana, ka taea pea e koe te whakamahi desmopressin me te aroturuki tupato. Heoi, ko te hunga e whai ana i te ngoikore ngākau nui, i ngā whakaeke ngākau tata nei, i te pēhanga toto tiketike kāore i te whakahaerehia, kāore rātou e whakamahi i tēnei rongoā.

Ka tīmata pea tō tākuta ki te horopeta iti ake, ā, ka mātakitaki pinepine i a koe mēnā he mate tō ngākau. Ka mātakitaki rātou i ngā tohu o te pupuri wai, ngā huringa o te pēhanga toto, me te pōraruraru o ngā tohu o tō ngākau.

Me Pēhea Taku Mahi Mēnā Ka Whakamahia E Au Te Nui Rawa O Te Desmopressin?

Mēnā ka inu koe i te nui rawa o te desmopressin, whakapā atu ki tō tākuta, ki te mana whakahaere paitini rānei i te wā tonu, ina koa i inu koe i te nui atu i te rua o tō horopeta. Kaua e tatari kia kite mēnā ka puta ngā tohu.

Ko ngā tohu o te horopeta nui ko te mamae nui o te upoko, te rangirua, te whakapairuaki, te ruaki, me te pikinga tere o te taumaha mai i te pupuri wai. I ngā wā tino nui, ka pā mai pea te hopu, te uaua rānei ki te manawa, e hiahia ana kia āwhina hauora ohorere.

I te wā e tatari ana koe mō te āwhina hauora, whakawhāitihia tō inu wai, me te mātakitaki i a koe anō mō te pōrarurahu o ngā tohu. Kaua e ngana ki te whakapairuaki i a koe anō, kua mimiti kē te rongoā mā roto i ngā kiko o tō waha.

Ko te ārai te mea nui, no reira me titiro tonu ki tō horopeta, me te pupuri i tō rongoā i roto i tōna ipu taketake me te tapanga mārama. Mēnā ka wareware pinepine koe mēnā kua inu koe i tō horopeta, whakaarohia te whakamahi i te kaiwhakarite pire, te whakatakoto rānei i ngā whakamaharatanga waea.

Me Pēhea Taku Mahi Mēnā Ka Ngaro I Ahau Tētahi Horopeta Desmopressin?

Mēnā ka ngaro i a koe tētahi horopeta desmopressin, inumia i te wā e mahara ana koe, ki te kore e tata ana te wā mō tō horopeta e whai ake nei. Kaua e inu i ngā horopeta e rua i te wā kotahi hei utu mō tētahi i ngaro.

Mō te mōmiti i te moenga, te mimi rānei i te pō, ko te ngaro i tētahi horopeta i te ahiahi ko te tikanga ka puta ngā tohu i taua pō, engari ka taea e koe te hoki ki tō hōtaka noa i te rā e whai ake nei. Kaua e inu i te rongoā atu hei utu.

Mēnā he mate huka insipidus tōu, ka ngaro i a koe tētahi horopeta, ka kite pea koe i te nui haere o te matewai me te mimi tae noa ki tō horopeta e whai ake nei. Whakapā atu ki tō tākuta mēnā ka ngaro pinepine i a koe ngā horopeta, nā te mea ka tohu pea tēnei kei te hiahia koe i tētahi hōtaka horopeta rerekē.

Ka taea e te whakatakoto whakamaharatanga i runga i tō waea, te hono rānei i tō rongoā ki tētahi rāpoi o ia rā, te āwhina i te ārai i ngā horopeta kua ngaro. E kitea ana e ētahi tāngata he āwhina ki te tango i ā rātou rongoā i te wā kotahi i ia rā.

Āhea Ānei Ka Taea e Au te Kati te Tango Desmopressin?

Kaua rawa e mutu te tango desmopressin ohorere, me te kore e kōrero tuatahi ki tō tākuta. E whakawhirinaki ana te wā ki tō āhuatanga me te pai o tō urupare ki te rongoā.

Mō te mimi i te moenga, ka tohutohu pea tō tākuta ki te whakamutu i te rongoā i muri i te 3-6 marama kia kite mena kua whakatau noa te raruraru. He maha ngā tamariki e tipu ana i te mimi i te moenga, nō reira ka āwhina ngā okiokinga wā ki te whakatau mena e tika ana te rongoā tonu.

Ko ngā tāngata e whai ana i te mate huka insipidus tūturu te tikanga e hiahia ana ki te rongoā mō te ora katoa, engari ka taea e tō tākuta te whakatika i tō horopeta, te whakamātau rānei i ngā okiokinga rongoā i raro i te tirotiro āta. Ka taea e ētahi tāngata e whai ana i te mate huka insipidus rangitahi te whakamutu i te rongoā i te wā e whakatau ana tō rātou āhuatanga taketake.

Ka hiahia pea tō tākuta ki te aroturuki i a koe i te wā e whakamutu ana i te desmopressin, i te mea ka hoki tere mai ngā tohumate. Ka tohutohu pea rātou ki te whakaiti i tō horopeta i te wā haere, kaua ki te whakamutu ohorere, e whakawhirinaki ana ki tō āhuatanga motuhake.

Ka Taea e Au te Inu waipiro i te wā e Tango ana i te Desmopressin?

Me karo koe i te waipiro i te wā e tango ana i te desmopressin, i te mea ka taea e ia te whakanui i tō tūponotanga ki ngā pānga taha kino, ina koa te paitini wai me ngā taumata konutai iti. E pā ana te waipiro ki te āhua o te tukatuka o tō tinana i te rongoā me ngā wai.

Ka taea hoki e te waipiro te whakapōrearea i ētahi o ngā pānga taha o te desmopressin, tae atu ki te whanoke, te mamae o te upoko, me te whakapairuaki. Ka taea hoki e ia te whakararu i tō kounga moe, ka pā ki ngā āhuatanga pēnei i te mimi i te moenga.

Mēnā ka whiriwhiri koe ki te inu waipiro i ētahi wā, whakawhāitihia koe ki ngā rahinga iti me te whakanui i tō aroturuki mō ngā pānga taha. Kōrerohia te whakamahi waipiro ki tō tākuta, i te mea ka hiahia pea rātou ki te whakatika i tō hōtaka rongoā, ki te whakarato rānei i ētahi atu whakatūpato.

Kia mahara ka noho te waipiro ki roto i tō tinana mō ngā hāora maha, nā reira he mea nui te wā mēnā kei te tango koe i te desmopressin mō ngā tohumate o te pō. Ka taea e tō tākuta te whakarato i ngā tohutohu motuhake i runga i tō hōtaka inenga me tō hītori hauora.